Clinical Trials

Showing trials with last updates posted in 2025.

NCT04260802 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
73 Participants

A Study to Evaluate the Safety and Pharmacokinetics of OC-001 in Patients With Locally Advanced or Metastatic Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-09-24
Completion: 2026-03-31
Conditions
Cancer Neoplasms Metastatic Cancer Triple Negative Breast Cancer Gastric Cancer Cervical Cancer Ovarian Cancer Hepatocellular Carcinoma Squamous Cell Carcinoma of Head and Neck Urothelial Carcinoma Urothelial Neoplasm Non Small Cell Lung Cancer Renal Cell Carcinoma Locally Advanced Solid Tumor Locally Advanced Malignant Neoplasm Squamous Cell Carcinoma Sarcoma Merkel Cell Carcinoma Bladder Cancer
Interventions
DRUG
No Results Yet
NCT04246086 | RECRUITING | PHASE1/PHASE2
237 Participants

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Mosunetuzumab + Lenalidomide (+Len), and the Safety, Tolerability, and Pharmacokinetics of SC Versus IV Mosunetuzumab + Len in Participants With Follicular Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-08-12
Completion: 2030-10-15
Conditions
Follicular Lymphoma
Interventions
DRUG
No Results Yet
NCT04245397 | RECRUITING | PHASE1
151 Participants

Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-06-30
Completion: 2028-03-31
Conditions
Myelodysplastic Syndromes
Interventions
DRUG
No Results Yet
NCT04199143 | COMPLETED | NA
30 Participants

Brain Reactivity to Nitrous Oxyde in Depression : an MRI and Ultrasound Study (PROTOBRAIN Pilote)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-02-20
Completion: 2021-06-10
Conditions
Treatment Resistant Depression Nitrous Oxyde
Interventions
DRUG DEVICE
No Results Yet
NCT04195607 | COMPLETED
298 Participants

Epidemiological Profile of Children With Early Caries.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2019-11-19
Completion: 2023-12-14
Conditions
Dental Caries
No Results Yet
NCT04195347 | RECRUITING | PHASE1/PHASE2
42 Participants

Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-09-04
Completion: 2027-01-31
Conditions
Acute Pancreatitis
Interventions
DRUG
No Results Yet
NCT04179708 | COMPLETED | NA
88 Participants

Effectiveness of Pain Neuroscience Education Compared to a Conventional Education for Patients With Chronic Low Back Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-01-06
Completion: 2024-02-10
Conditions
Chronic Low-back Pain
Interventions
OTHER
No Results Yet
NCT04179695 | RECRUITING | NA
120 Participants

Evaluation of a New Communication Aid Tool to Favor Global Patient Centered Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-07-21
Completion: 2026-12-31
Conditions
Parkinson's Disease
Interventions
OTHER
No Results Yet
NCT04164212 | RECRUITING | PHASE4
25 Participants

Live Attenuated Influenza Vaccine as a Nasal Model for Influenza Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-09-01
Completion: 2026-01-31
Conditions
Influenza
Interventions
DRUG
No Results Yet
NCT04154943 | COMPLETED | PHASE2
79 Participants

Study of Cemiplimab in Patients With Type of Skin Cancer Stage II to IV Cutaneous Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-03-10
Completion: 2021-12-01
Conditions
Cutaneous Squamous Cell Carcinoma
Interventions
DRUG
NCT04147884 | ACTIVE_NOT_RECRUITING | NA
4 Participants

A Feasibility Study of the Millipede Transcatheter Annuloplasty Ring System in Patients With Functional Mitral Regurgitation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-11-13
Completion: 2021-12-17
Conditions
Mitral Regurgitation Functional Mitral Valve Disease Cardiovascular Diseases
Interventions
DEVICE
No Results Yet
NCT04146870 | RECRUITING
200 Participants

Nutritional Status of Patients After Hematopoietic Stem Cell Transplantation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2018-10-01
Completion: 2025-12-30
Conditions
Nutrition Hematopoietic Stem Cell Transplantation
Interventions
OTHER
No Results Yet
NCT04116437 | ACTIVE_NOT_RECRUITING | PHASE2
90 Participants

Zanubrutinib (BGB-3111) in Participants With Previously Treated B-Cell Lymphoma Intolerant of Prior Bruton Tyrosine Kinase Inhibitor (BTKi) Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-10-15
Completion: 2025-12-31
Conditions
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Mantle Cell Lymphoma Marginal Zone Lymphoma Waldenstrom Macroglobulinemia
Interventions
DRUG
No Results Yet
NCT04093167 | RECRUITING | PHASE2/PHASE3
230 Participants

Study of CTDNA Response Adaptive Immuno-Chemotherapy in NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-05-26
Completion: 2026-12-31
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT04089358 | ACTIVE_NOT_RECRUITING | PHASE3
384 Participants

Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors, the StepByStep Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-12-07
Completion: 2025-12-31
Conditions
Hematopoietic and Lymphoid Cell Neoplasm Malignant Solid Neoplasm
Interventions
OTHER DEVICE BEHAVIORAL
No Results Yet
NCT04083976 | ACTIVE_NOT_RECRUITING | PHASE2
316 Participants

A Study of Erdafitinib in Participants With Advanced Solid Tumors and Fibroblast Growth Factor Receptor (FGFR) Gene Alterations

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-11-20
Completion: 2023-12-04
Conditions
Advanced Solid Tumor
Interventions
DRUG
NCT04081636 | COMPLETED | NA
840 Participants

Prostate Biopsy, Transrectal vs. Transperineal: Efficacy and Complications

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-09-02
Completion: 2024-12-31
Conditions
Prostate Cancer PSA Infection
Interventions
PROCEDURE
No Results Yet
NCT04075266 | ACTIVE_NOT_RECRUITING | PHASE2
23 Participants

A Study of Ocrelizumab in Children and Adolescents With Relapsing-Remitting Multiple Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2020-01-09
Completion: 2023-10-05
Conditions
Multiple Sclerosis
Interventions
DRUG
NCT04054167 | RECRUITING | PHASE2
80 Participants

Ultra Low Dose Radiation Delivered Before or After Chemotherapy-Free Targeted Therapy in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-06-14
Completion: 2027-12-31
Conditions
Recurrent Mantle Cell Lymphoma Refractory Mantle Cell Lymphoma
Interventions
DRUG
No Results Yet
NCT04018066 | COMPLETED | NA
34 Participants

The Effect of Concord Grape Polyphenol-soy Protein Isolate Complex (GP-SPI) on Gut Microbiota

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-06-28
Completion: 2019-12-20
Conditions
Mechanisms, Defense
Interventions
DIETARY_SUPPLEMENT
NCT04000477 | TERMINATED | NA
3 Participants

Comparison of 2 Types of Cervical Specimens in Patients With a Pathological Screening Smear

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-11-05
Completion: 2019-11-25
Conditions
Cervical Cancer Pathological Screening Smear
Interventions
DEVICE
No Results Yet
NCT03959007 | COMPLETED | NA
70 Participants

Impact of Supportive Care on the Experience of Hospitalization of Patients Staying in the Protected Area of the Department of Blood Diseases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-03-15
Completion: 2022-10-27
Conditions
Acute Leukemia Hematopoietic Stem Cell Transplantation (SCT) Aplasia
Interventions
OTHER
No Results Yet
NCT03944512 | TERMINATED | PHASE3
102 Participants

Pravastatin to Prevent Preeclampsia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-07-17
Completion: 2021-06-06
Conditions
Preeclampsia Obstetric Labor Complications Hypertension in Pregnancy
Interventions
DRUG OTHER
NCT03932903 | RECRUITING | NA
60 Participants

Mobile Health Intervention to Support Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-31
Completion: 2026-07-31
Conditions
Acute Lymphoblastic Leukemia Lymphoblastic Lymphoma
Interventions
BEHAVIORAL
No Results Yet
NCT03922269 | COMPLETED
200 Participants

Trans People Living With HIV Throughout Europe

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2019-10-11
Completion: 2025-12-17
Conditions
HIV Infections Gender Identity Human Immunodeficiency Virus
No Results Yet
NCT03919955 | COMPLETED | PHASE2
117 Participants

A Novel Pharmacological Therapy for Obstructive Sleep Apnea

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-09-03
Completion: 2023-09-07
Conditions
Sleep Apnea
Interventions
DRUG
NCT03888144 | COMPLETED | PHASE4
81 Participants

Study of Ketorolac Versus Opioid for Pain After Endoscopy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2017-10-13
Completion: 2021-08-01
Conditions
Kidney Calculi Ureteral Calculi
Interventions
DRUG
NCT03887936 | ACTIVE_NOT_RECRUITING | PHASE4
92 Participants

Testosterone Therapy and Bone Quality in Men With Diabetes and Hypogonadism

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-10-01
Completion: 2025-10-08
Conditions
Type 2 Diabetes Mellitus Hypogonadism
Interventions
DRUG
NCT03879447 | ACTIVE_NOT_RECRUITING
110 Participants

Effectiveness and Safety of Korean Medicine for Low Back Pain or Sciatica Due to Lumbar Stenosis/Spondylolisthesis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2019-06-24
Completion: 2022-03-03
Conditions
Lumbar Spinal Stenosis Lumbar Spondylolisthesis Low Back Pain Sciatica Neurogenic Claudication
Interventions
DRUG PROCEDURE
No Results Yet
NCT03878446 | ACTIVE_NOT_RECRUITING | PHASE2
62 Participants

A Research Study in Children Born Small and Who Stayed Small. Treatment is Somapacitan Once a Week Compared to Norditropin® Once a Day

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-07-04
Completion: 2021-05-05
Conditions
Short Stature Children Born Small for Gestational Age (SGA)
Interventions
DRUG
NCT03876262 | ACTIVE_NOT_RECRUITING | PHASE3
323 Participants

Safety and Efficacy of Annual or Biannual Doses of Moxidectin or Ivermectin for Onchocerciasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2021-05-03
Completion: 2024-07-31
Conditions
Onchocerciasis
Interventions
DRUG
No Results Yet
NCT03851237 | COMPLETED | PHASE1
69 Participants

CCR2 PET for Pancreatic Cancer Imaging and Prediction of Response to Standard and CCR2-Targeted Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-01-02
Completion: 2025-12-19
Conditions
Pancreatic Ductal Adenocarcinoma
Interventions
DRUG DEVICE
No Results Yet
NCT03836040 | ACTIVE_NOT_RECRUITING | PHASE3
457 Participants

Efficacy and Safety of Erenumab in Pediatric Participants With Episodic Migraine

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-07-19
Completion: 2025-11-19
Conditions
Migraine
Interventions
DRUG OTHER
No Results Yet
NCT03828344 | NOT_YET_RECRUITING | PHASE1
16 Participants

Safety and Tolerability of a Single Intravenous Infusion of BX-U001 in Refractory Rheumatoid Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2026-12-01
Completion: 2027-12-31
Conditions
Rheumatoid Arthritis
Interventions
BIOLOGICAL
No Results Yet
NCT03823833 | COMPLETED
82 Participants

Oocyte Freezing for Fertility Preservation in Benign Ovarian Tumors

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2021-07-28
Completion: 2025-04-04
Conditions
Endometriosis Dermoid Cyst Mucinous Cyst
No Results Yet
NCT03821636 | RECRUITING | NA
396 Participants

Impact of Long Alimentary Limb or Long Biliary Limb Roux-en-Y Gastric Bypass on Type 2 Diabetes Remission in Severely Obese Patients.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-06-16
Completion: 2026-06-30
Conditions
Diabetes Mellitus Type 2 in Obese
Interventions
PROCEDURE
No Results Yet
NCT03816189 | COMPLETED
70 Participants

Role of Eosinophil in Fibrogenesis of Systemic Sclerosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2018-10-03
Completion: 2022-04-05
Conditions
Systemic Sclerosis Systemic Scleroderma
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03810807 | COMPLETED | PHASE1
22 Participants

Study of Dacomitinib and Osimertinib for Patients With Advanced EGFR Mutant Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2019-01-17
Completion: 2025-12-15
Conditions
Metastatic Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
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