Clinical Trials
Showing trials with last updates posted in 2025.
36
Participants
A Study to Evaluate the Safety and Efficacy of ExAblate Subthalomotomy for the Treatment of Parkinson's Disease Motor Features
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-02-27
Completion:
2020-06-15
Conditions
Parkinson Disease
Interventions
DEVICE
No Results Yet
120
Participants
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-07-11
Completion:
2023-07-19
Conditions
Psoriasis
Interventions
DRUG
8
Participants
Dynamic of Immunocompetent Populations in Patients Treated With Extracorporeal Photopheresis in Chronic Graft Versus Host Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-05-07
Completion:
2019-12-02
Conditions
Graft Versus Host Disease
Extracorporeal Photopheresis
Interventions
DIAGNOSTIC_TEST
No Results Yet
136
Participants
A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-03-02
Completion:
2021-08-31
Conditions
Prostatic Neoplasms, Castration-Resistant
Interventions
DRUG
478
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-01-26
Completion:
2019-02-07
Conditions
Chronic Plaque Psoriasis
Moderate to Severe Plaque Psoriasis
Interventions
DRUG
OTHER
435
Participants
A Study With a Initial Treatment Period Followed by a Randomized-withdrawal Period to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-02-05
Completion:
2018-12-28
Conditions
Chronic Plaque Psoriasis
Moderate to Severe Chronic Plaque Psoriasis
Psoriatic Arthritis
Interventions
DRUG
OTHER
43
Participants
Oleclumab (MEDI9447) Epidermal Growth Factor Receptor Mutant (EGFRm) Non-small Cell Lung Cancer (NSCLC) Novel Combination Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-05-08
Completion:
2021-05-24
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
BIOLOGICAL
DRUG
567
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to Placebo and an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-12-06
Completion:
2019-01-08
Conditions
Chronic Plaque Psoriasis
Moderate to Severe Chronic Plaque Psoriasis
Psoriatic Arthritis
Interventions
DRUG
OTHER
40
Participants
Development of an Epileptic Seizure Detection Algorithm by Continuous Analysis of the Electrocardiogram
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2017-12-13
Completion:
2019-12-12
Conditions
Seizures
Epilepsy
Electrocardiography
No Results Yet
13
Participants
Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-01-18
Completion:
2023-07-21
Conditions
Angiosarcoma
Epithelioid Hemangioendothelioma
Interventions
DRUG
500
Participants
Study of Seladelpar in Participants With Primary Biliary Cholangitis (PBC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-12-12
Completion:
2028-11-30
Conditions
Primary Biliary Cirrhosis
Interventions
DRUG
No Results Yet
390
Participants
A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-11-07
Completion:
2024-05-01
Conditions
Smoldering Multiple Myeloma
Interventions
DRUG
90
Participants
Paracetamol Metabolism Research in Postoperative Hepatic Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2016-11-20
Completion:
2018-04-30
Conditions
Paracetamol Causing Adverse Effects in Therapeutic Use
Hepatic Disease
Interventions
DRUG
PROCEDURE
No Results Yet
56
Participants
Description of the Functional Evolution of Diffuse Infiltrating Pneumonia Associated With Systemic Scleroderma.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2018-04-10
Completion:
2024-12-31
Conditions
Systemic Sclerosis
Interventions
OTHER
No Results Yet
105
Participants
Comprehensive Segmental Revision System
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2016-04-30
Completion:
2035-12-31
Conditions
Degenerative Disease
Oncology
Revision Surgery
Trauma
Rheumatoid Arthritis
Interventions
DEVICE
No Results Yet
258
Participants
Determinants of Patient Delay in Doctor Consultation in Oeso-gastric Cancers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-02-01
Completion:
2025-02-07
Conditions
Oesophageal Carcinoma
Gastric Adenocarcinoma
Interventions
OTHER
No Results Yet
24
Participants
Study of Pembrolizumab and Mifepristone in Patients With Advanced HER2-negative Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2018-02-12
Completion:
2025-09-30
Conditions
Triple Negative Breast Neoplasms
Breast Cancer
Interventions
DRUG
No Results Yet
402
Participants
Efficacy and Safety of Vedolizumab IV in Chinese Participants With Ulcerative Colitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-08-03
Completion:
2027-09-24
Conditions
Moderately to Severely Active Ulcerative Colitis
Interventions
DRUG
No Results Yet
51
Participants
Novel PET/CT and Treatment Strategies to Reduce PTS Following DVT
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-12-20
Completion:
2025-06-08
Conditions
Deep Venous Thrombosis
Post-thrombotic Syndrome
Interventions
DEVICE
No Results Yet
1645
Participants
The First 1,000 Days Program: Maternal-Child Obesity Prevention in Early Life
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2016-08-09
Completion:
2021-03-18
Conditions
Overweight and Obesity
Social Determinants of Health
Physical Activity
Sleep
Feeding Behavior
Diet Habit
Interventions
BEHAVIORAL
No Results Yet
77
Participants
SX-682 Treatment in Subjects With Metastatic Melanoma Concurrently Treated With Pembrolizumab
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2019-06-12
Completion:
2026-08-31
Conditions
Melanoma Stage III
Melanoma Stage IV
Interventions
DRUG
BIOLOGICAL
No Results Yet
50
Participants
Biomarkers of Antidepressant Resistance
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-06-16
Completion:
2021-01-12
Conditions
Depression
Interventions
OTHER
BIOLOGICAL
DEVICE
No Results Yet
159
Participants
A Study of Axicabtagene Ciloleucel in Participants With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-06-06
Completion:
2024-12-20
Conditions
Follicular Lymphoma
Marginal Zone Lymphoma
Indolent Non-Hodgkin Lymphoma
Interventions
BIOLOGICAL
DRUG
33
Participants
Oxygenation of Paravertebral Muscles During Exercise in Chronic Low Back Pain Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-01-11
Completion:
2024-12-10
Conditions
Low Back Pain
Rehabilitation Program
Muscular Weakness
Interventions
OTHER
No Results Yet
6
Participants
Surgical Resection Plus Chemotherapy Versus Chemotherapy Alone in Oligometastatic Stage IV Gastric Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2021-08-25
Completion:
2024-08-28
Conditions
Gastric Adenocarcinoma
Interventions
DRUG
PROCEDURE
No Results Yet
116
Participants
Study of MGL-3196 in Patients With Heterozygous Familial Hypercholesterolemia (HeFH)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-02-23
Completion:
2018-01-15
Conditions
Heterozygous Familial Hypercholesterolemia
Interventions
DRUG
77
Participants
Is Caffeine an Environmental Modifier in Huntington's Disease?
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2017-10-11
Completion:
2024-04-12
Conditions
Huntington Disease
No Results Yet
40
Participants
Metabolomics in Assessing the Quality of Kidney Transplants Retained on a LifePort® Perfusion Machine
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-03-15
Completion:
2019-09-15
Conditions
Renal Transplantation
Interventions
DEVICE
No Results Yet
154
Participants
Improving Outcomes Using Technology for Children Who Are DHH
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2016-10-31
Completion:
2025-12-31
Conditions
Hearing Loss
Language Development
Social Behavior
Interventions
BEHAVIORAL
No Results Yet
542
Participants
Identification of Epigenetic Risk Factors for Ischemic Complication During the TAVR Procedure in the Elderly
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2017-03-09
Completion:
2026-02-28
Conditions
Cognitive Decline
Stroke
No Results Yet
120
Participants
Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2016-11-17
Completion:
2026-05-31
Conditions
Endometriosis
Infertility
Interventions
PROCEDURE
No Results Yet
23
Participants
Home-Based, Online, Mindfulness and Cognitive Training for Soldiers and Veterans With TBI
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2017-03-31
Completion:
2020-08-30
Conditions
Mild Traumatic Brain Injury
Interventions
OTHER
No Results Yet
125
Participants
Phase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2016-10-18
Completion:
2017-10-25
Conditions
Non-alcoholic Steatohepatitis
Interventions
DRUG
72
Participants
Better Life by Nutrition During Adulthood
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2017-02-23
Completion:
2022-03-25
Conditions
Cardiovascular Risk Factor
No Results Yet
337
Participants
Tepotinib Phase II in NSCLC Harboring MET Alterations (VISION)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2016-09-13
Completion:
2022-05-16
Conditions
Advanced (Stage IIIB/IV) Non-small Cell Lung Cancer (NSCLC) With MET Exon 14 (METex14) Skipping Alterations or MET Amplification
Lung Adenocarcinoma Stage IIIB/IV
Interventions
DRUG
5000
Participants
Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2011-07-31
Completion:
2027-04-30
Conditions
Wolfram Syndrome
Diabetes Mellitus
Optic Nerve Atrophy
Deafness
Diabetes Insipidus
Ataxia
No Results Yet
304
Participants
Study of Pembrolizumab (MK-3475) vs. Brentuximab Vedotin in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (MK-3475-204/KEYNOTE-204)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-23
Start Date:
2016-05-23
Completion:
2025-12-10
Conditions
Hodgkin Lymphoma
Interventions
BIOLOGICAL
No Results Yet
61
Participants
Cancer DNA Detection in Blood and Urine
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2014-11-30
Completion:
2022-04-30
Conditions
Prostate Cancer
Interventions
PROCEDURE
No Results Yet
200
Participants
Fragility Fracture Liaison Service and Anti-osteoporosis Medication Monitoring Service Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2015-09-30
Completion:
2026-12-31
Conditions
Osteoporosis
Fracture
No Results Yet
2187
Participants
MRI Background Parenchymal Enhancement as a Risk Factor for Breast Cancer: The IMAGINg and Epidemiology (IMAGINE) Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-23
Start Date:
2014-11-30
Completion:
2026-11-30
Conditions
Breast Cancer
No Results Yet
Showing 40 trials per page