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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06977568 | TERMINATED | PHASE2
1 Participants

A Study to Evaluate an Intra-Articular Injection of ZILRETTA Versus Triamcinolone Acetonide, Immediate Release in Subjects With Osteoarthritis of the Hip

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-07-25
Completion: 2025-10-16
Conditions
Osteoarthritis of Hip
Interventions
DRUG
No Results Yet
NCT06975878 | RECRUITING | PHASE3
1080 Participants

Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-05-22
Completion: 2027-08-18
Conditions
Pneumococcal Immunization Healthy Volunteers
Interventions
BIOLOGICAL
No Results Yet
NCT06971744 | RECRUITING | PHASE2
38 Participants

Autophagy Maintenance (AUTOMAIN)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-12-18
Completion: 2028-06-18
Conditions
Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT06968715 | COMPLETED | NA
40 Participants

Hydrogen-Rich Water and Metabolic Health in Adults: A 12-Week Randomized Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-04-01
Completion: 2025-10-30
Conditions
Metabolic Syndrome
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06967506 | ACTIVE_NOT_RECRUITING | NA
50 Participants

Evaluation of Blowing Exercises Utilizing a Breathing Exercise Device in Otitis Media With Effusion

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-25
Completion: 2025-12-12
Conditions
Otitis Media With Effusion (OME) Otitis Media With Effusion in Children Breathing Exercise
Interventions
DEVICE
No Results Yet
NCT06965374 | RECRUITING
270 Participants

Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants With Advanced Parkinson Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-04
Completion: 2027-06-30
Conditions
Parkinson Disease
No Results Yet
NCT06963021 | RECRUITING | PHASE3
200 Participants

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-05-30
Completion: 2027-07-31
Conditions
Major Depressive Disorder
Interventions
DRUG
No Results Yet
NCT06962137 | RECRUITING | PHASE2
100 Participants

Phase II RAINSPOT: Zolbetuximab-Paclitaxel-Ramucirumab for CLDN18.2 Positive Gastro-esophageal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-12-11
Completion: 2029-12-31
Conditions
Gastric Cancer Adenocarcinoma Metastatic Gastric Adenocarcinoma and Gastroesophageal Junction Adenocarcinoma
Interventions
DRUG OTHER
No Results Yet
NCT06958796 | RECRUITING | PHASE4
80 Participants

Strategic Help With Immunoglobulin to Enhance Protect Against Late Disease (CMV)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-11-27
Completion: 2027-12-30
Conditions
Cytomegalovirus Organ Transplant Kidney Transplant; Complications Liver Transplant Complications Simultaneous Liver-Kidney Transplantation; Complications
Interventions
DRUG
No Results Yet
NCT06954090 | ENROLLING_BY_INVITATION | PHASE4
50 Participants

Urinary Proteomics to Guide Early Intervention to Prevent Complications in Type 2 Diabetes - a Feasibility Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-11-20
Completion: 2026-11-30
Conditions
Type 2 DM Type 2 DM /Diabetic Nephropathy Albuminuria
Interventions
DRUG
No Results Yet
NCT06952907 | RECRUITING | NA
340 Participants

Femoral Versus Radial Invasive Arterial Pressure Monitoring in Cardiac Surgery Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-15
Completion: 2027-07-01
Conditions
Vasoplegia Syndrome Vasoplegia Cardiac Surgical Procedures Arterial Pressure Hypotension During Surgery Hypotension Postprocedural Norepinephrine
Interventions
OTHER
No Results Yet
NCT06952738 | RECRUITING
200 Participants

Investigating Periprosthetic Fracture Cultures in Arthroplasty

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2025-10-01
Completion: 2027-04-30
Conditions
Periprosthetic Fracture Around Prosthetic Joint Implant
Interventions
OTHER
No Results Yet
NCT06949553 | RECRUITING
250 Participants

An Observational Study to Learn More About Vasomotor Symptoms Burden and Treatment Patterns in Menopausal Women Before and After Participating in OASIS Studies

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2025-04-30
Completion: 2028-05-15
Conditions
Vasomotor Symptoms (VMS) Associated With Menopause
Interventions
OTHER
No Results Yet
NCT06947993 | RECRUITING | PHASE2
224 Participants

Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-05-16
Completion: 2028-11-27
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
NCT06935656 | COMPLETED | NA
192 Participants

Effectiveness of Three Executive Function Interventions on Direct and Far Transfer in Chilean School Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-05-05
Completion: 2025-11-26
Conditions
Executive Functions
Interventions
OTHER
No Results Yet
NCT06934538 | RECRUITING | PHASE1/PHASE2
90 Participants

First-in-human Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-17
Completion: 2028-06-30
Conditions
Unresectable Metastatic Colorectal Cancer Unresectable Locally Advanced Colorectal Cancer
Interventions
BIOLOGICAL
No Results Yet
NCT06925321 | RECRUITING | PHASE3
219 Participants

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-08-26
Completion: 2028-02-29
Conditions
Invasive Mold Infections
Interventions
DRUG
No Results Yet
NCT06923527 | RECRUITING | PHASE2
50 Participants

Circulating Tumor DNA

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-09-30
Completion: 2027-09-30
Conditions
ER+ Breast Cancer
Interventions
DRUG
No Results Yet
NCT06920680 | RECRUITING
1834 Participants

ColoReg: A Register for Gastrointestinal Endoscopy Reports and Examination Videos

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-01
Completion: 2026-10-31
Conditions
Colorectal Cancer Colonoscopy Polypectomy
No Results Yet
NCT06919666 | RECRUITING | PHASE1/PHASE2
29 Participants

NT219 Combined With Standard of Care Biologic Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-12
Completion: 2030-02-28
Conditions
Head and Neck Cancer Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT06917690 | RECRUITING | PHASE3
6 Participants

A Study to Learn About the Safety and Efficacy of the Drug Oleogel-S10 in Japanese Patients With Epidermolysis Bullosa

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-04-18
Completion: 2026-03-31
Conditions
Epidermolysis Bullosa Junctional Epidermolysis Bullosa Epidermolysis Bullosa, Dystrophic Epidermolysis Bullosa, Junctional Skin Abnormalities Connective Tissue Disease Collagen Diseases Skin Diseases Genetic Diseases, Inborn Congenital Abnormalities
Interventions
DRUG
No Results Yet
NCT06914609 | RECRUITING | PHASE3
158 Participants

REVEAL: A Phase 3 Study of ION582 in Angelman Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-10
Completion: 2027-08-31
Conditions
Angelman Syndrome
Interventions
DRUG
No Results Yet
NCT06910540 | RECRUITING | NA
144 Participants

ACU-TENS on Pain and Stress Reduction Before and During TUGOR

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-09-01
Completion: 2027-12-31
Conditions
Oocyte Retrieival and Post Operative Pain Control Acupuncture
Interventions
OTHER
No Results Yet
NCT06909669 | NOT_YET_RECRUITING | NA
184 Participants

Ultra-brief Psychological Treatments for Emotional Symptoms and Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-02-28
Completion: 2028-06-30
Conditions
Depression - Major Depressive Disorder Generalized Anxiety Disorder Generalized Anxiety Anxiety Somatoform Disorders Somatic Symptom Disorder (DSM-5) Somatization Emotional Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT06907537 | COMPLETED | NA
44 Participants

A Study to Verify the Sleep-improving Effects of the Test Food Consumption

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-04-03
Completion: 2025-12-15
Conditions
Healthy Japanese
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06907147 | RECRUITING | NA
175 Participants

SPYRAL GEMINI Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-05-01
Completion: 2029-12-22
Conditions
Cardiovascular Diseases Chronic Kidney Diseases Diabetes Mellitus Hypertension Vascular Diseases
Interventions
DEVICE
No Results Yet
NCT06906939 | NOT_YET_RECRUITING | EARLY_PHASE1
30 Participants

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-02-01
Completion: 2029-06-30
Conditions
Knee Osteoarthritis Depression
Interventions
DEVICE
No Results Yet
NCT06906926 | RECRUITING | NA
80 Participants

Harmony TPV EMEA PMS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-07-30
Completion: 2027-07-31
Conditions
Severe Pulmonary Valve Regurgitation
Interventions
RADIATION
No Results Yet
NCT06894979 | RECRUITING | PHASE1
54 Participants

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-02-01
Completion: 2028-03-31
Conditions
Childhood Astrocytoma Childhood Diffuse Intrinsic Pontine Glioma Childhood Diffuse Midline Glioma Childhood Glioblastoma Childhood Malignant Glioma
Interventions
DRUG PROCEDURE RADIATION OTHER
No Results Yet
NCT06892522 | RECRUITING | PHASE1/PHASE2
440 Participants

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion Alone or in Combination With Oral, IV, Subcutaneous Daratumumab; Lenalidomide; Dexamethasone; Carfilzomib

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-30
Completion: 2036-02-29
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06892145 | RECRUITING | PHASE1
12 Participants

Clinical Trial of CD19 Targeted CAR-T Cell in Refractory Adult SLE

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-06-12
Completion: 2026-05-04
Conditions
Systemic Lupus Erythematosus (SLE) Refractory
Interventions
BIOLOGICAL
No Results Yet
NCT06888011 | RECRUITING | NA
1024 Participants

iAmHealthy Clinical Practice Guideline (CPG)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-09-06
Completion: 2028-11-30
Conditions
Pediatric Obesity Rural Health Clinical Practice Guideline
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06883448 | RECRUITING | NA
220 Participants

Implementation of Home Monitoring in Patients With Pulmonary Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-02
Completion: 2026-09-01
Conditions
Pulmonary Fibrosis Interstitial Lung Disease (ILD)
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT06874790 | RECRUITING | NA
700 Participants

RCT for Latina Mental Health Using Web-Based Apps

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-07-09
Completion: 2028-11-30
Conditions
Mental Health Anxiety Depression Well-Being, Psychological
Interventions
BEHAVIORAL
No Results Yet
NCT06868368 | COMPLETED | NA
53 Participants

Perceptions of Vaping Products

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-03
Completion: 2025-11-04
Conditions
Abuse Tobacco Exposure
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT06868290 | RECRUITING | PHASE2
126 Participants

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-13
Completion: 2029-06-07
Conditions
ANCA Associated Vasculitis (AAV)
Interventions
BIOLOGICAL OTHER DRUG
No Results Yet
NCT06868212 | RECRUITING | PHASE3
400 Participants

A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-07-11
Completion: 2027-02-22
Conditions
Chronic Spontaneous Urticaria (CSU)
Interventions
DRUG
No Results Yet
NCT06866418 | RECRUITING
600 Participants

Phagenyx® Registry Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2025-09-15
Completion: 2035-09-30
Conditions
Dysphagia
Interventions
DEVICE
No Results Yet
NCT06862193 | RECRUITING | NA
440 Participants

Effectiveness of Digital Intervention (HM4MH-app) on Perinatal Psychological Wellbeing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-03-10
Completion: 2027-12-31
Conditions
Perinatal Mental Health Mobile Application Behavior
Interventions
BEHAVIORAL
No Results Yet
NCT06844669 | RECRUITING | PHASE2
40 Participants

HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving HER2-directed Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-04-16
Completion: 2026-02-28
Conditions
HER2-positive Breast Cancer HER2+ Breast Cancer
Interventions
DRUG
No Results Yet
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