Clinical Trials Updated in 2025

NCT06977568 | TERMINATED | PHASE2

1 Participants

A Study to Evaluate an Intra-Articular Injection of ZILRETTA Versus Triamcinolone Acetonide, Immediate Release in Subjects With Osteoarthritis of the Hip

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-07-25

Completion: 2025-10-16

Conditions

Osteoarthritis of Hip

Interventions

DRUG

No Results Yet

NCT06975878 | RECRUITING | PHASE3

1080 Participants

Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From Approximately 2 Months of Age

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-05-22

Completion: 2027-08-18

Conditions

Pneumococcal Immunization Healthy Volunteers

Interventions

BIOLOGICAL

No Results Yet

NCT06971744 | RECRUITING | PHASE2

38 Participants

Autophagy Maintenance (AUTOMAIN)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-12-18

Completion: 2028-06-18

Conditions

Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT06968715 | COMPLETED | NA

40 Participants

Hydrogen-Rich Water and Metabolic Health in Adults: A 12-Week Randomized Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-04-01

Completion: 2025-10-30

Conditions

Metabolic Syndrome

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06967506 | ACTIVE_NOT_RECRUITING | NA

50 Participants

Evaluation of Blowing Exercises Utilizing a Breathing Exercise Device in Otitis Media With Effusion

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-09-25

Completion: 2025-12-12

Conditions

Otitis Media With Effusion (OME) Otitis Media With Effusion in Children Breathing Exercise

Interventions

DEVICE

No Results Yet

NCT06965374 | RECRUITING

270 Participants

Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants With Advanced Parkinson Disease

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-04

Completion: 2027-06-30

Conditions

Parkinson Disease

No Results Yet

NCT06963021 | RECRUITING | PHASE3

200 Participants

NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-05-30

Completion: 2027-07-31

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT06962137 | RECRUITING | PHASE2

100 Participants

Phase II RAINSPOT: Zolbetuximab-Paclitaxel-Ramucirumab for CLDN18.2 Positive Gastro-esophageal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-12-11

Completion: 2029-12-31

Conditions

Gastric Cancer Adenocarcinoma Metastatic Gastric Adenocarcinoma and Gastroesophageal Junction Adenocarcinoma

Interventions

DRUG OTHER

No Results Yet

NCT06958796 | RECRUITING | PHASE4

80 Participants

Strategic Help With Immunoglobulin to Enhance Protect Against Late Disease (CMV)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-11-27

Completion: 2027-12-30

Conditions

Cytomegalovirus Organ Transplant Kidney Transplant; Complications Liver Transplant Complications Simultaneous Liver-Kidney Transplantation; Complications

Interventions

DRUG

No Results Yet

NCT06954090 | ENROLLING_BY_INVITATION | PHASE4

50 Participants

Urinary Proteomics to Guide Early Intervention to Prevent Complications in Type 2 Diabetes - a Feasibility Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-11-20

Completion: 2026-11-30

Conditions

Type 2 DM Type 2 DM /Diabetic Nephropathy Albuminuria

Interventions

DRUG

No Results Yet

NCT06952907 | RECRUITING | NA

340 Participants

Femoral Versus Radial Invasive Arterial Pressure Monitoring in Cardiac Surgery Patients

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-15

Completion: 2027-07-01

Conditions

Vasoplegia Syndrome Vasoplegia Cardiac Surgical Procedures Arterial Pressure Hypotension During Surgery Hypotension Postprocedural Norepinephrine

Interventions

OTHER

No Results Yet

NCT06952738 | RECRUITING

200 Participants

Investigating Periprosthetic Fracture Cultures in Arthroplasty

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2025-10-01

Completion: 2027-04-30

Conditions

Periprosthetic Fracture Around Prosthetic Joint Implant

Interventions

OTHER

No Results Yet

NCT06949553 | RECRUITING

250 Participants

An Observational Study to Learn More About Vasomotor Symptoms Burden and Treatment Patterns in Menopausal Women Before and After Participating in OASIS Studies

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2025-04-30

Completion: 2028-05-15

Conditions

Vasomotor Symptoms (VMS) Associated With Menopause

Interventions

OTHER

No Results Yet

NCT06947993 | RECRUITING | PHASE2

224 Participants

Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-05-16

Completion: 2028-11-27

Conditions

Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT06935656 | COMPLETED | NA

192 Participants

Effectiveness of Three Executive Function Interventions on Direct and Far Transfer in Chilean School Children

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-05-05

Completion: 2025-11-26

Conditions

Executive Functions

Interventions

OTHER

No Results Yet

NCT06934538 | RECRUITING | PHASE1/PHASE2

90 Participants

First-in-human Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-17

Completion: 2028-06-30

Conditions

Unresectable Metastatic Colorectal Cancer Unresectable Locally Advanced Colorectal Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06925321 | RECRUITING | PHASE3

219 Participants

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-08-26

Completion: 2028-02-29

Conditions

Invasive Mold Infections

Interventions

DRUG

No Results Yet

NCT06923527 | RECRUITING | PHASE2

50 Participants

Circulating Tumor DNA

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-09-30

Completion: 2027-09-30

Conditions

ER+ Breast Cancer

Interventions

DRUG

No Results Yet

NCT06920680 | RECRUITING

1834 Participants

ColoReg: A Register for Gastrointestinal Endoscopy Reports and Examination Videos

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2024-10-01

Completion: 2026-10-31

Conditions

Colorectal Cancer Colonoscopy Polypectomy

No Results Yet

NCT06919666 | RECRUITING | PHASE1/PHASE2

29 Participants

NT219 Combined With Standard of Care Biologic Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-12

Completion: 2030-02-28

Conditions

Head and Neck Cancer Head and Neck Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT06917690 | RECRUITING | PHASE3

6 Participants

A Study to Learn About the Safety and Efficacy of the Drug Oleogel-S10 in Japanese Patients With Epidermolysis Bullosa

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-04-18

Completion: 2026-03-31

Conditions

Epidermolysis Bullosa Junctional Epidermolysis Bullosa Epidermolysis Bullosa, Dystrophic Epidermolysis Bullosa, Junctional Skin Abnormalities Connective Tissue Disease Collagen Diseases Skin Diseases Genetic Diseases, Inborn Congenital Abnormalities

Interventions

DRUG

No Results Yet

NCT06914609 | RECRUITING | PHASE3

158 Participants

REVEAL: A Phase 3 Study of ION582 in Angelman Syndrome

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-10

Completion: 2027-08-31

Conditions

Angelman Syndrome

Interventions

DRUG

No Results Yet

NCT06910540 | RECRUITING | NA

144 Participants

ACU-TENS on Pain and Stress Reduction Before and During TUGOR

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-09-01

Completion: 2027-12-31

Conditions

Oocyte Retrieival and Post Operative Pain Control Acupuncture

Interventions

OTHER

No Results Yet

NCT06909669 | NOT_YET_RECRUITING | NA

184 Participants

Ultra-brief Psychological Treatments for Emotional Symptoms and Disorders

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2026-02-28

Completion: 2028-06-30

Conditions

Depression - Major Depressive Disorder Generalized Anxiety Disorder Generalized Anxiety Anxiety Somatoform Disorders Somatic Symptom Disorder (DSM-5) Somatization Emotional Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT06907537 | COMPLETED | NA

44 Participants

A Study to Verify the Sleep-improving Effects of the Test Food Consumption

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-04-03

Completion: 2025-12-15

Conditions

Healthy Japanese

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06907147 | RECRUITING | NA

175 Participants

SPYRAL GEMINI Pilot Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-05-01

Completion: 2029-12-22

Conditions

Cardiovascular Diseases Chronic Kidney Diseases Diabetes Mellitus Hypertension Vascular Diseases

Interventions

DEVICE

No Results Yet

NCT06906939 | NOT_YET_RECRUITING | EARLY_PHASE1

30 Participants

A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2026-02-01

Completion: 2029-06-30

Conditions

Knee Osteoarthritis Depression

Interventions

DEVICE

No Results Yet

NCT06906926 | RECRUITING | NA

80 Participants

Harmony TPV EMEA PMS

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-07-30

Completion: 2027-07-31

Conditions

Severe Pulmonary Valve Regurgitation

Interventions

RADIATION

No Results Yet

NCT06894979 | RECRUITING | PHASE1

54 Participants

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2026-02-01

Completion: 2028-03-31

Conditions

Childhood Astrocytoma Childhood Diffuse Intrinsic Pontine Glioma Childhood Diffuse Midline Glioma Childhood Glioblastoma Childhood Malignant Glioma

Interventions

DRUG PROCEDURE RADIATION OTHER

No Results Yet

NCT06892522 | RECRUITING | PHASE1/PHASE2

440 Participants

A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving Etentamig (ABBV-383) as an Intravenous (IV) Infusion Alone or in Combination With Oral, IV, Subcutaneous Daratumumab; Lenalidomide; Dexamethasone; Carfilzomib

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-30

Completion: 2036-02-29

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT06892145 | RECRUITING | PHASE1

12 Participants

Clinical Trial of CD19 Targeted CAR-T Cell in Refractory Adult SLE

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-06-12

Completion: 2026-05-04

Conditions

Systemic Lupus Erythematosus (SLE) Refractory

Interventions

BIOLOGICAL

No Results Yet

NCT06888011 | RECRUITING | NA

1024 Participants

iAmHealthy Clinical Practice Guideline (CPG)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-09-06

Completion: 2028-11-30

Conditions

Pediatric Obesity Rural Health Clinical Practice Guideline

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT06883448 | RECRUITING | NA

220 Participants

Implementation of Home Monitoring in Patients With Pulmonary Fibrosis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2024-10-02

Completion: 2026-09-01

Conditions

Pulmonary Fibrosis Interstitial Lung Disease (ILD)

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06874790 | RECRUITING | NA

700 Participants

RCT for Latina Mental Health Using Web-Based Apps

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-07-09

Completion: 2028-11-30

Conditions

Mental Health Anxiety Depression Well-Being, Psychological

Interventions

BEHAVIORAL

No Results Yet

NCT06868368 | COMPLETED | NA

53 Participants

Perceptions of Vaping Products

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-03-03

Completion: 2025-11-04

Conditions

Abuse Tobacco Exposure

Interventions

OTHER BEHAVIORAL

No Results Yet

NCT06868290 | RECRUITING | PHASE2

126 Participants

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-03-13

Completion: 2029-06-07

Conditions

ANCA Associated Vasculitis (AAV)

Interventions

BIOLOGICAL OTHER DRUG

No Results Yet

NCT06868212 | RECRUITING | PHASE3

400 Participants

A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-07-11

Completion: 2027-02-22

Conditions

Chronic Spontaneous Urticaria (CSU)

Interventions

DRUG

No Results Yet

NCT06866418 | RECRUITING

600 Participants

Phagenyx® Registry Study

Study Type: OBSERVATIONAL

Last Updated: 2025-12-22

Start Date: 2025-09-15

Completion: 2035-09-30

Conditions

Dysphagia

Interventions

DEVICE

No Results Yet

NCT06862193 | RECRUITING | NA

440 Participants

Effectiveness of Digital Intervention (HM4MH-app) on Perinatal Psychological Wellbeing

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-03-10

Completion: 2027-12-31

Conditions

Perinatal Mental Health Mobile Application Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT06844669 | RECRUITING | PHASE2

40 Participants

HER2HEART-US: Prevention of Cardiotoxicity in Breast Cancer Patients Receiving HER2-directed Therapy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-22

Start Date: 2025-04-16

Completion: 2026-02-28

Conditions

HER2-positive Breast Cancer HER2+ Breast Cancer

Interventions

DRUG

No Results Yet