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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06576440 | COMPLETED | NA
24 Participants

Effects of Ghrelin Administration on Motivation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-02
Completion: 2024-12-20
Conditions
Major Depressive Disorder
Interventions
DRUG
No Results Yet
NCT06572228 | RECRUITING | PHASE4
250 Participants

Efficacy of Dupilumab Added to Medium Dose Inhaled Corticosteroid/Long-acting Beta-agonist (ICS/LABA) in Comparison to ICS Dose Escalation to High Dose ICS/LABA in Adolescent and Adult Patients With Uncontrolled Asthma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-08-26
Completion: 2026-12-31
Conditions
Asthma
Interventions
DRUG
No Results Yet
NCT06571994 | COMPLETED | NA
60 Participants

The Plastic Exposure Reduction Transforms Health Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-05
Completion: 2025-07-03
Conditions
Endocrine Disruptors Inflammation Cardiometabolic Risk Factors
Interventions
BEHAVIORAL
No Results Yet
NCT06568939 | RECRUITING | PHASE2
150 Participants

A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-01-20
Completion: 2028-02-29
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06568237 | RECRUITING | PHASE2
200 Participants

A Study to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy (MSA): A Safety and Efficacy Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-02
Completion: 2027-05-20
Conditions
Multiple System Atrophy
Interventions
DRUG
No Results Yet
NCT06540326 | RECRUITING | PHASE2
100 Participants

Clinical Study of Second-line Treatment in Advanced Colorectal Cancer With Chemotherapy With Bevacizumab or Cetuximab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-11-12
Completion: 2026-04-15
Conditions
Colorectal Cancer Metastatic
Interventions
DRUG
No Results Yet
NCT06538038 | RECRUITING
538 Participants

Prospective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-17
Completion: 2028-08-31
Conditions
Non Small Cell Lung Cancer Epidermal Growth Factor Receptor Gene Mutation Stage III Lung Cancer Stage IV Lung Cancer
Interventions
DRUG
No Results Yet
NCT06534892 | ACTIVE_NOT_RECRUITING | PHASE3
10212 Participants

An Extension and Crossover Vaccination Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus Given to Adults 60 Years of Age and Above Who Participated in RSV OA=ADJ-006 Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-08-01
Completion: 2026-09-30
Conditions
Respiratory Syncytial Virus Infections
Interventions
BIOLOGICAL
No Results Yet
NCT06531824 | RECRUITING | PHASE3
11000 Participants

EASi-KIDNEY™ (The Studies of Heart & Kidney Protection With BI 690517 in Combination With Empagliflozin)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-08-13
Completion: 2028-08-30
Conditions
Kidney Disease, Chronic
Interventions
DRUG
No Results Yet
NCT06525623 | RECRUITING | NA
50 Participants

Initial Resuscitation for Acute Kidney Injury in Cirrhosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-12
Completion: 2026-09-30
Conditions
Cirrhosis, Liver Acute Kidney Injury Hepatorenal Syndrome
Interventions
OTHER
No Results Yet
NCT06523608 | RECRUITING
600 Participants

Prediction of Decompensation and HCC Development in Advanced Chronic Liver Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-01
Completion: 2027-09-30
Conditions
Liver Diseases Hepatocellular Carcinoma Hepatocarcinoma Advanced Chronic Liver Disease
Interventions
OTHER
No Results Yet
NCT06522204 | COMPLETED | NA
60 Participants

Comparing the Gastric Emptying Times of Underweight and Healthy-weight School-aged Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-07-30
Completion: 2025-12-15
Conditions
Preoperative Fasting
Interventions
DRUG
No Results Yet
NCT06520865 | COMPLETED
560 Participants

TIDE Project: Biomarker Discovery for Chronic Tinnitus Diagnosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-08-01
Completion: 2025-11-30
Conditions
Tinnitus
Interventions
OTHER
No Results Yet
NCT06513962 | RECRUITING | PHASE3
60 Participants

Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-02-27
Completion: 2029-10-30
Conditions
Hematopoietic and Lymphatic System Neoplasm Malignant Solid Neoplasm
Interventions
OTHER PROCEDURE DRUG
No Results Yet
NCT06513208 | RECRUITING | PHASE4
140 Participants

Ketorolac Effects on Post-operative Pain and Lumbar Fusion

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2026-01-31
Completion: 2027-06-30
Conditions
Lumbar Spinal Fusion
Interventions
DRUG
No Results Yet
NCT06500273 | RECRUITING | PHASE2
250 Participants

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-06-18
Completion: 2027-08-24
Conditions
Large B-cell Lymphoma
Interventions
GENETIC DRUG DEVICE
No Results Yet
NCT06493604 | COMPLETED | PHASE3
116 Participants

A Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-06-24
Completion: 2025-02-27
Conditions
Dry Eye Disease
Interventions
DRUG
No Results Yet
NCT06487585 | RECRUITING | PHASE4
100 Participants

ANG-First Trial (Angiotensin II as First-Line Vasopressor Therapy in Cardiac Surgery)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-05-06
Completion: 2026-01-31
Conditions
Vasodilatory Hypotension During or After Cardiac Surgery
Interventions
DRUG
No Results Yet
NCT06470048 | RECRUITING | PHASE2
200 Participants

A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-09
Completion: 2027-07-06
Conditions
Diffuse Cutaneous Systemic Sclerosis
Interventions
DRUG
No Results Yet
NCT06468124 | RECRUITING
20 Participants

Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2025-05-27
Completion: 2026-06-30
Conditions
Breast Neoplasms
No Results Yet
NCT06465069 | RECRUITING | PHASE1
420 Participants

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-07-01
Completion: 2027-05-31
Conditions
Metastatic Solid Tumor Recurrent Solid Tumor Advanced Solid Tumor Urinary Bladder Neoplasm Triple Negative Breast Cancer Non-small Cell Lung Cancer Esophageal Cancer Pancreatic Cancer Ovarian Cancer Cervical Cancer Head and Neck Squamous Cell Carcinoma Prostate Cancer Renal Pelvis Cancer Bladder Cancer
Interventions
DRUG
No Results Yet
NCT06462391 | ACTIVE_NOT_RECRUITING | NA
50 Participants

Adapting and Piloting Acceptance and Commitment Therapy (ACT) for Severe Premenstrual Mood Symptoms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-12-01
Completion: 2026-06-30
Conditions
Premenstrual Dysphoric Disorder Premenstrual Exacerbation of Mood Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06459024 | RECRUITING
4000 Participants

Master Framework For Relapse or Refractory Acute Myeloid Leukemia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-06-28
Completion: 2032-07-31
Conditions
Acute Myeloid Leukemia, in Relapse Acute Myeloid Leukemia Refractory
Interventions
OTHER
No Results Yet
NCT06452277 | RECRUITING | PHASE3
278 Participants

A Study to Learn More About How Well Sevabertinib (BAY 2927088) Works and How Safe it is Compared With Standard Treatment, in Participants Who Have Advanced Non-small Cell Lung Cancer (NSCLC) With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-08-28
Completion: 2027-10-28
Conditions
Advanced Non-small Cell Lung Cancer HER2 Mutation
Interventions
DRUG
No Results Yet
NCT06445062 | RECRUITING | PHASE1/PHASE2
1130 Participants

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-05-24
Completion: 2027-05-15
Conditions
Colorectal Cancer CRC Pancreatic Ductal Adenocarcinoma PDAC Gastrointestinal Cancer Metastatic Pancreatic Ductal Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT06444087 | ACTIVE_NOT_RECRUITING
192 Participants

Patient's Perspective on the Evolution of Hidradenitis Suppurativa Burden After Secukinumab Initiation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-06-17
Completion: 2027-06-30
Conditions
Hidradenitis Suppurativa
Interventions
OTHER
No Results Yet
NCT06435468 | RECRUITING | NA
400 Participants

Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-02-26
Completion: 2035-02-27
Conditions
Systemic Lupus Autoimmune Diseases Autoinflammatory Disease Genetic Disease
Interventions
GENETIC OTHER
No Results Yet
NCT06430866 | RECRUITING | PHASE3
154 Participants

Pharmacokinetic Similarity Between ABP 234 and Keytruda® (Pembrolizumab)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-12
Completion: 2026-12-14
Conditions
Early-stage Non-squamous Non-small Cell Lung Cancer (NSCLC)
Interventions
DRUG
No Results Yet
NCT06420349 | TERMINATED | PHASE1
7 Participants

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-05-31
Completion: 2025-08-12
Conditions
Advanced Cholangiocarcinoma Metastatic Cholangiocarcinoma Refractory Cholangiocarcinoma Stage III Hilar Cholangiocarcinoma AJCC v8 Stage III Intrahepatic Cholangiocarcinoma AJCC v8 Stage IV Hilar Cholangiocarcinoma AJCC v8 Stage IV Intrahepatic Cholangiocarcinoma AJCC v8
Interventions
PROCEDURE BIOLOGICAL
No Results Yet
NCT06417125 | COMPLETED | PHASE4
324 Participants

Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-05-22
Completion: 2025-09-22
Conditions
Behavior Problem
Interventions
DRUG
No Results Yet
NCT06414330 | COMPLETED | PHASE3
124 Participants

Ringer Acetate Based Modified Del Nido Cardioplegia Solution Versus HTK Solution Cardioplegia Solution in Cardiac Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-06-01
Completion: 2025-11-12
Conditions
Cardiac Ischemia
Interventions
BIOLOGICAL
No Results Yet
NCT06412666 | RECRUITING | PHASE2/PHASE3
55 Participants

A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-05-29
Completion: 2030-01-31
Conditions
Pediatric Symptomatic Obstructive Hypertrophic Cardiomyopathy
Interventions
DRUG
No Results Yet
NCT06408506 | COMPLETED | NA
20 Participants

In-patient Comparison of Immediately Loaded and Non-loaded Submerged and Transgingival Healed Implants Within 4 Months

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-09-28
Completion: 2025-10-29
Conditions
Jaw, Edentulous
Interventions
PROCEDURE
No Results Yet
NCT06389656 | COMPLETED | NA
17 Participants

Addressing Weight Bias Internalization to Improve Adolescent Weight Management Outcomes: Open Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-04-08
Completion: 2025-02-15
Conditions
Body Weight Weight Bias Weight Stigma Weight
Interventions
BEHAVIORAL
No Results Yet
NCT06377215 | RECRUITING | NA
121 Participants

Understanding Aided Speech Perception in Noise

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-11-16
Completion: 2028-03-01
Conditions
Hearing Impairment, Sensorineural Spatial Perception Aging Hearing Aids
Interventions
DEVICE
No Results Yet
NCT06375681 | RECRUITING | NA
1600 Participants

Effectiveness of Cognitive Training in Older and Younger Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-01
Completion: 2028-01-31
Conditions
Cognitive Change
Interventions
BEHAVIORAL
No Results Yet
NCT06368817 | RECRUITING | PHASE2
240 Participants

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-22
Completion: 2033-11-04
Conditions
Basal Ganglia Germinoma Central Nervous System Germinoma Diabetes Insipidus Pineal Region Germinoma Suprasellar Germinoma Thalamic Germinoma
Interventions
RADIATION PROCEDURE DRUG OTHER
No Results Yet
NCT06368622 | RECRUITING
500 Participants

Evolve China PMCF Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-04-24
Completion: 2027-11-30
Conditions
Intracranial Aneurysm
Interventions
DEVICE
No Results Yet
NCT06368427 | COMPLETED
10 Participants

Change in Patient-repOrted Outcomes in COPD Patients Newly Initiated on TRIXEO AEROSPHERE in Real worlD

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-04-30
Completion: 2025-11-17
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
DRUG
No Results Yet
NCT06349512 | RECRUITING | NA
60 Participants

68Ga-FAPI-46 PET/CT for Predicting Histological Response in Triple-negative Breast Cancer (FAP-IT)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-14
Completion: 2032-11-30
Conditions
Triple Negative Breast Cancer
Interventions
PROCEDURE
No Results Yet
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