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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06414330 | COMPLETED | PHASE3
124 Participants

Ringer Acetate Based Modified Del Nido Cardioplegia Solution Versus HTK Solution Cardioplegia Solution in Cardiac Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-06-01
Completion: 2025-11-12
Conditions
Cardiac Ischemia
Interventions
BIOLOGICAL
No Results Yet
NCT06412666 | RECRUITING | PHASE2/PHASE3
55 Participants

A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-05-29
Completion: 2030-01-31
Conditions
Pediatric Symptomatic Obstructive Hypertrophic Cardiomyopathy
Interventions
DRUG
No Results Yet
NCT06408506 | COMPLETED | NA
20 Participants

In-patient Comparison of Immediately Loaded and Non-loaded Submerged and Transgingival Healed Implants Within 4 Months

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2017-09-28
Completion: 2025-10-29
Conditions
Jaw, Edentulous
Interventions
PROCEDURE
No Results Yet
NCT06389656 | COMPLETED | NA
17 Participants

Addressing Weight Bias Internalization to Improve Adolescent Weight Management Outcomes: Open Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-04-08
Completion: 2025-02-15
Conditions
Body Weight Weight Bias Weight Stigma Weight
Interventions
BEHAVIORAL
No Results Yet
NCT06377215 | RECRUITING | NA
121 Participants

Understanding Aided Speech Perception in Noise

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-11-16
Completion: 2028-03-01
Conditions
Hearing Impairment, Sensorineural Spatial Perception Aging Hearing Aids
Interventions
DEVICE
No Results Yet
NCT06375681 | RECRUITING | NA
1600 Participants

Effectiveness of Cognitive Training in Older and Younger Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-01
Completion: 2028-01-31
Conditions
Cognitive Change
Interventions
BEHAVIORAL
No Results Yet
NCT06368817 | RECRUITING | PHASE2
240 Participants

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-22
Completion: 2033-11-04
Conditions
Basal Ganglia Germinoma Central Nervous System Germinoma Diabetes Insipidus Pineal Region Germinoma Suprasellar Germinoma Thalamic Germinoma
Interventions
RADIATION PROCEDURE DRUG OTHER
No Results Yet
NCT06368622 | RECRUITING
500 Participants

Evolve China PMCF Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-04-24
Completion: 2027-11-30
Conditions
Intracranial Aneurysm
Interventions
DEVICE
No Results Yet
NCT06368427 | COMPLETED
10 Participants

Change in Patient-repOrted Outcomes in COPD Patients Newly Initiated on TRIXEO AEROSPHERE in Real worlD

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-04-30
Completion: 2025-11-17
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
DRUG
No Results Yet
NCT06349512 | RECRUITING | NA
60 Participants

68Ga-FAPI-46 PET/CT for Predicting Histological Response in Triple-negative Breast Cancer (FAP-IT)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-14
Completion: 2032-11-30
Conditions
Triple Negative Breast Cancer
Interventions
PROCEDURE
No Results Yet
NCT06349057 | RECRUITING | PHASE4
120 Participants

The Effect of the Anticholinergic Burden Following Elective Coronary Artery Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-01-01
Completion: 2025-10-01
Conditions
Postoperative Recovery Length of Hospital Stay Postoperative Complications
Interventions
DRUG
No Results Yet
NCT06346392 | RECRUITING | PHASE3
572 Participants

AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-03-04
Completion: 2026-05-14
Conditions
Gastric Cancer Gastroesophageal Junction Cancer
Interventions
DRUG
No Results Yet
NCT06344104 | ACTIVE_NOT_RECRUITING | PHASE3
326 Participants

A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-04-08
Completion: 2025-11-24
Conditions
Uncontrolled Hypertension Resistant Hypertension
Interventions
DRUG
No Results Yet
NCT06342908 | RECRUITING | PHASE1
6 Participants

A Vaccine (Neoantigen-Targeted ppDC) for the Treatment of H3 G34-mutant Diffuse Hemispheric Glioma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-06-14
Completion: 2027-03-08
Conditions
Diffuse Hemispheric Glioma, H3 G34-Mutant
Interventions
PROCEDURE BIOLOGICAL DRUG
No Results Yet
NCT06341452 | RECRUITING | NA
130 Participants

Comparison of Individualized Sodium Management Versus Standard Treatment in Hemodialysis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-12-16
Completion: 2026-12-31
Conditions
End Stage Renal Disease
Interventions
DEVICE
No Results Yet
NCT06332144 | COMPLETED | NA
41 Participants

Predicting Language and Literacy Growth in Children With ASD Using Statistical Learning

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-01-13
Completion: 2025-08-31
Conditions
Autism Spectrum Disorder Language Development Literacy
Interventions
BEHAVIORAL
No Results Yet
NCT06331312 | RECRUITING | PHASE3
288 Participants

Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-06-28
Completion: 2028-08-22
Conditions
Polymyalgia Rheumatica
Interventions
BIOLOGICAL
No Results Yet
NCT06330064 | RECRUITING | PHASE2
520 Participants

A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-04-10
Completion: 2028-07-25
Conditions
Recurrent or Metastatic Solid Tumors
Interventions
DRUG
No Results Yet
NCT06329375 | RECRUITING | NA
160 Participants

Food Insecurity Reduction & Strategy Team

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-10-07
Completion: 2026-03-31
Conditions
Diabetes Mellitus, Type 2 Food Insecurity Diabetes Mellitus, Type 1
Interventions
OTHER
No Results Yet
NCT06327074 | ACTIVE_NOT_RECRUITING | NA
40 Participants

Testing the Engaged Approach to Lung Cancer Screening

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-03-11
Completion: 2024-10-30
Conditions
Lung Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06324357 | RECRUITING | PHASE1/PHASE2
768 Participants

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-06-03
Completion: 2029-01-08
Conditions
Metastatic Breast Cancer Metastatic Gastric Adenocarcinoma Gastroesophageal Junction Adenocarcinoma Esophageal Adenocarcinoma Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT06323109 | RECRUITING
80 Participants

US Imaging for the Assessment of LUTS

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2023-11-28
Completion: 2027-01-31
Conditions
Lower Urinary Tract Symptoms BPH
Interventions
DEVICE
No Results Yet
NCT06315556 | RECRUITING
200 Participants

An Observational Study to Collect Data on How Aflibercept (Eylea) Given Using a Paediatric Dosing Device is Used in Preterm Babies With Retinopathy of Prematurity in the United Kingdom (UK)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-03-05
Completion: 2027-03-31
Conditions
Retinopathy of Prematurity Preterm Infants
Interventions
DRUG
No Results Yet
NCT06310005 | COMPLETED | PHASE1
36 Participants

A Study in Healthy Japanese Men to Test How Well Different Doses of BI 3006337 Are Tolerated

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-04-19
Completion: 2024-10-31
Conditions
Healthy
Interventions
DRUG
Results Available
NCT06306586 | RECRUITING | NA
60 Participants

A Digital Treatment for Adolescents With Eating Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-03-11
Completion: 2027-01-01
Conditions
Eating Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT06302439 | RECRUITING
1000 Participants

PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2024-07-25
Completion: 2034-05-31
Conditions
Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 Deficiency ATP-Binding Cassette Subfamily C Member 6 Deficiency
Interventions
OTHER
No Results Yet
NCT06296641 | SUSPENDED | NA
60 Participants

Needs Navigation for Caregivers of AYAs

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-02-16
Completion: 2026-07-31
Conditions
Cancer in Adolescence
Interventions
BEHAVIORAL
No Results Yet
NCT06270602 | RECRUITING
15000 Participants

The ONCOCAMP Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-22
Start Date: 2023-07-14
Completion: 2026-05-31
Conditions
Oncology
Interventions
OTHER
No Results Yet
NCT06266338 | RECRUITING | PHASE2
30 Participants

Study of Pembrolizumab and Lenvatinib in Metastatic and Recurrent Cervix Cancer (LenPem Cervix)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-03-11
Completion: 2026-10-31
Conditions
Cervix Cancer Cervical Cancer
Interventions
DRUG
No Results Yet
NCT06255353 | COMPLETED | NA
118 Participants

Effect of Different Feeding Modes in Intracerebral Hemorrhage

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-02-28
Completion: 2025-10-19
Conditions
Intracerebral Hemorrhage
Interventions
DEVICE BEHAVIORAL
No Results Yet
NCT06249984 | RECRUITING | NA
80 Participants

Effects of Tobacco Cut and Nicotine Form on the Abuse Liability of Moist Snuff

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-12-20
Completion: 2027-03-01
Conditions
Tobacco-Related Carcinoma
Interventions
PROCEDURE BEHAVIORAL OTHER
No Results Yet
NCT06247189 | RECRUITING | NA
30 Participants

ICOPE Program Feasibility in the Management of Myeloma Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2025-12-03
Completion: 2026-12-03
Conditions
Frailty Multiple Myeloma
Interventions
OTHER
No Results Yet
NCT06246643 | ACTIVE_NOT_RECRUITING | PHASE2
13 Participants

A Study of Continued Treatment With Regorafenib in Participants With Solid Tumors Who Have Participated in Other Bayer Studies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-01-24
Completion: 2028-04-27
Conditions
Solid Malignant Tumors
Interventions
DRUG
No Results Yet
NCT06244212 | RECRUITING | NA
30 Participants

Topical Treatment for Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-09-19
Completion: 2026-07-31
Conditions
Atopic Dermatitis
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT06240208 | RECRUITING | NA
40 Participants

Physical Inactivity and Appetite Regulation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-03-01
Completion: 2026-02-01
Conditions
Overweight
Interventions
BEHAVIORAL
No Results Yet
NCT06239116 | RECRUITING | PHASE1/PHASE2
150 Participants

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-03-05
Completion: 2027-11-01
Conditions
Hypothalamic Obesity Prader-Willi Syndrome PWS
Interventions
DRUG
No Results Yet
NCT06236061 | ACTIVE_NOT_RECRUITING | PHASE3
718 Participants

Study of Efficacy and Safety of LCZ696/Amlodipine in Grade 1 and 2 Hypertension Patients Uncontrolled by LCZ696 Monotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-04-08
Completion: 2025-05-28
Conditions
Hypertension
Interventions
DRUG OTHER
No Results Yet
NCT06229366 | ACTIVE_NOT_RECRUITING | PHASE1
142 Participants

[Ac-225]-PSMA-62 Trial in Oligometastatic Hormone Sensitive and Metastatic Castration Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-04-03
Completion: 2027-09-30
Conditions
Prostate Cancer Metastatic Castration-resistant Prostate Cancer Oligometastatic Prostate Carcinoma Hormone Sensitive Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06228053 | RECRUITING | PHASE2
53 Participants

Study of SX-682 Plus Enzalutamide in Men With ARPI-Resistant Metastatic Castration Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2024-11-18
Completion: 2026-06-30
Conditions
Metastatic Castration-resistant Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06218511 | ACTIVE_NOT_RECRUITING | PHASE1
10 Participants

A Phase I Trial of IMA970A Plus Montanide in Combination With Durvalumab (Anti-PD-L1)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-22
Start Date: 2022-11-22
Completion: 2025-08-28
Conditions
Hepatocellular Carcinoma
Interventions
BIOLOGICAL COMBINATION_PRODUCT OTHER
No Results Yet
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