Clinical Trials Updated in 2025

NCT06919094 | RECRUITING | NA

50 Participants

A Virtual Life Story Club Intervention to Improve Loneliness and Apathy in Community-Dwelling Older Adults

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-08-15

Completion: 2026-08-31

Conditions

Apathy Loneliness Reminiscence Therapy

Interventions

BEHAVIORAL

No Results Yet

NCT06918990 | RECRUITING | PHASE2

100 Participants

Treatment of Antibody-Mediated Rejection (ABMR) With CarBel

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2026-01-15

Completion: 2027-06-30

Conditions

Kidney Transplant Rejection

Interventions

BIOLOGICAL

No Results Yet

NCT06912217 | COMPLETED | NA

30 Participants

Comparison of the Effects of Robotic Rehabilitation, Functional Electrical Stimulation and Occupational Therapy on Upper Extremity and Hand Functions in Tetraplegic Patients With Spinal Cord Injury

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-04-01

Completion: 2025-09-01

Conditions

Tetraplegia/Tetraparesis

Interventions

DEVICE OTHER

No Results Yet

NCT06907199 | NOT_YET_RECRUITING | PHASE1

104 Participants

Daily Nitrofurantoin Versus Bladder Fulguration Plus Daily Nitrofurantoin for Women With Recurrent Urinary Tract Infections

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2026-01-31

Completion: 2028-07-01

Conditions

Recurrent UTIs Cystitis Recurrent

Interventions

PROCEDURE DRUG

No Results Yet

NCT06899308 | RECRUITING

363 Participants

Health Surveillance at Constructor University Bremen (CUB) and Among HAW-Hamburg Employees

Study Type: OBSERVATIONAL

Last Updated: 2025-12-19

Start Date: 2025-03-17

Completion: 2026-06-30

Conditions

Social Isolation or Loneliness Anxiety Anxiety Depression (Mild or Not Persistent) Health Behavior Observational Study Stress, Psychological Emotional Stress Life Stress Psychological Stress Stress, Emotional Stress (Psychology) Substance Abuse Substance Addiction Substance Dependence Substance Use

No Results Yet

NCT06885697 | RECRUITING | PHASE1

100 Participants

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-07-08

Completion: 2034-06-01

Conditions

Mesothelioma Neoplasms Stomach Neoplasms Pancreatic Neoplasms Ovarian Neoplasms Lung Neoplasms Thymus Neoplasms Colonic Neoplasms

Interventions

DEVICE BIOLOGICAL DRUG

No Results Yet

NCT06885658 | COMPLETED | NA

358 Participants

Effectiveness of Visual Storytelling Intervention on Antibiotic Adherence in UTI Patients

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-06-03

Completion: 2025-08-30

Conditions

Uncomplicated Urinary Tract Infection Patient With Uncomplicated UTI

Interventions

BEHAVIORAL

No Results Yet

NCT06869434 | COMPLETED | NA

285 Participants

Thoraco Lumbar Vertebral Length and Bupivacaine Dosage in C-Section

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-05-20

Completion: 2025-12-01

Conditions

Obstetric Anesthesia Problems Bupivacaine Adverse Reaction

Interventions

PROCEDURE

No Results Yet

NCT06860763 | RECRUITING | NA

76 Participants

Acupuncture for ADHD: Acupoint Data Mining, Clinical Effectiveness, and Interviews to Explore Treatment Outcomes.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2024-10-15

Completion: 2026-04-15

Conditions

Acupuncture ADHD - Attention Deficit Disorder With Hyperactivity Children Interview Executive Functioning Quality of Life (QOL)

Interventions

DRUG DEVICE

No Results Yet

NCT06857253 | COMPLETED | PHASE1

82 Participants

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HRS-1301 in Healthy Subjects

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-03-18

Completion: 2025-08-11

Conditions

Hyperlipidemia

Interventions

DRUG

No Results Yet

NCT06855563 | ENROLLING_BY_INVITATION | NA

36000 Participants

Cities for Better Health Childhood Obesity Prevention Initiative

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-04-30

Completion: 2027-12-31

Conditions

Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT06845202 | RECRUITING | PHASE1/PHASE2

144 Participants

A Study to Evaluate ALN-4324 in Overweight to Obese Healthy Volunteers and in Overweight to Obese Patients With T2DM

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-03-03

Completion: 2027-08-31

Conditions

Obese or Overweight Healthy Volunteers Type 2 Diabetes Mellitus (T2DM)

Interventions

DRUG

No Results Yet

NCT06842901 | COMPLETED | NA

10 Participants

Feasibility Study on PoRi Device

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-04-07

Completion: 2025-07-15

Conditions

Hand Spasticity

Interventions

DEVICE

No Results Yet

NCT06842888 | COMPLETED | NA

24 Participants

Comparing Mirror Therapy Rehabilitation Device to Conventional Mirror Therapy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-03-31

Completion: 2025-08-19

Conditions

Stroke Pain Impaired Motor Function

Interventions

DEVICE BEHAVIORAL

No Results Yet

NCT06837454 | RECRUITING

600 Participants

French Prospective Observational Study in Patients Eligible for Systemic Therapy for Atopic Dermatitis (AD)

Study Type: OBSERVATIONAL

Last Updated: 2025-12-19

Start Date: 2025-02-04

Completion: 2027-05-13

Conditions

Atopic Dermatitis

No Results Yet

NCT06833073 | RECRUITING | PHASE2

308 Participants

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-03-11

Completion: 2031-09-03

Conditions

Urinary Bladder Neoplasms Non-Muscle Invasive Bladder Neoplasms Carcinoma in Situ

Interventions

BIOLOGICAL

No Results Yet

NCT06831344 | COMPLETED | PHASE1

25 Participants

A Study to Evaluate Two Vonoprazan Orally Disintegrating Tablet Formulations Administered Without Water or Mixed With Water and Administered Via a Syringe Relative to the Vonoprazan Tablet in Healthy Participants

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-02-14

Completion: 2025-04-05

Conditions

Healthy Volunteers

Interventions

DRUG

Results Available

NCT06823089 | RECRUITING | NA

15 Participants

Early Feasibility Study of Cartilage Defect Repair

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-11-06

Completion: 2031-10-31

Conditions

Osteoarthritis, Hip Femoroacetabular Impingement Osteonecrosis Trauma Related Injuries Avascular Necrosis of Bone of Hip Avascular Necrosis of Bone

Interventions

DEVICE

No Results Yet

NCT06810570 | RECRUITING

874 Participants

The Effect of Mobile Devices on the Development and Health of Young Children

Study Type: OBSERVATIONAL

Last Updated: 2025-12-19

Start Date: 2025-01-13

Completion: 2027-01-31

Conditions

Development and Health Behavior and Behavior Mechanisms Cognition Physical Health Parent-Child Relations Education Technology Use

No Results Yet

NCT06801327 | RECRUITING | NA

40 Participants

Comparison Between Conventional Respiratory Physiotherapy and the Simeox Device in Patients With Bronchiectasis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2024-12-01

Completion: 2026-09-01

Conditions

Bronchiectasis Adult

Interventions

DEVICE

No Results Yet

NCT06800586 | RECRUITING

300 Participants

Tumors and Respiratory System Diseases Due to Air Pollution: New Biomarkers of Exposure and Effects

Study Type: OBSERVATIONAL

Last Updated: 2025-12-19

Start Date: 2025-09-15

Completion: 2026-07-31

Conditions

COPD Lung Cancer (NSCLC) Leukemia

No Results Yet

NCT06797973 | RECRUITING | PHASE4

1312 Participants

Efficacy and Safety of Intrathecal Morphine for Postoperative Pain Management Following Planned Caesarean Section

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-07-15

Completion: 2027-05-31

Conditions

Caesarean Section Postoperative Pain

Interventions

DRUG

No Results Yet

NCT06791265 | COMPLETED | NA

7 Participants

Computer-guided Versus Conventional Eminectomy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-02-10

Completion: 2025-12-12

Conditions

TMJ - Dislocation of Temporomandibular Joint

Interventions

DEVICE PROCEDURE

No Results Yet

NCT06788535 | ACTIVE_NOT_RECRUITING | PHASE3

200 Participants

Research With I-124 EVuzamitide to Elucidate Cardiac AmyLoidosis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-01-14

Completion: 2026-02-13

Conditions

Cardiac Amyloidosis

Interventions

DRUG

No Results Yet

NCT06770595 | NOT_YET_RECRUITING | NA

100 Participants

Breastfeeding Education Through Clinical Demonstration for Primiparous Women to Prevent Sore Nipples and Engorgement

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-12-26

Completion: 2026-03-15

Conditions

Nipple Infection Nipple Discharge Engorgement

Interventions

BEHAVIORAL

No Results Yet

NCT06769685 | ENROLLING_BY_INVITATION

100 Participants

TPO Combined With TPORA for Solid Tumors Effectiveness of cTit Above Degree II

Study Type: OBSERVATIONAL

Last Updated: 2025-12-19

Start Date: 2025-02-27

Completion: 2026-01-31

Conditions

CTIT-Chemotherapy Induced Thrombocytopenia

Interventions

DRUG

No Results Yet

NCT06765798 | COMPLETED | NA

60 Participants

Adding Neural Mobilization to Mulligan Technique for Treatment of Patients With Chronic Tennis Elbow

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-01-01

Completion: 2025-06-01

Conditions

Tennis Elbow

Interventions

OTHER

No Results Yet

NCT06756477 | COMPLETED | NA

114 Participants

The Effect of Mindfulness Training on Premenstrual Syndrome Symptoms and Quality of Life

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-05-03

Completion: 2025-07-03

Conditions

Mindfulness Premenstrual Syndrome-PMS Quality of Life

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT06752850 | ACTIVE_NOT_RECRUITING | PHASE4

37 Participants

A Study to Investigate the Course of Synovial Hypertrophy in Patients With Haemophilia A on Efanesoctocog Alfa Prophylaxis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2024-12-19

Completion: 2026-12-31

Conditions

Haemophilia A (Moderate or Severe) Hemophilia, Classic Haemophilia Hemophilia Classic Hemophilia Synovial Hypertrophy

Interventions

DRUG

No Results Yet

NCT06750289 | RECRUITING | PHASE3

400 Participants

Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-03-28

Completion: 2027-11-02

Conditions

Eosinophilic Asthma

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06747806 | RECRUITING

500 Participants

Biobank Cardiac Surgery

Study Type: OBSERVATIONAL

Last Updated: 2025-12-19

Start Date: 2023-12-18

Completion: 2028-12-31

Conditions

Cardiovascular Diseases

Interventions

PROCEDURE

No Results Yet

NCT06743321 | NOT_YET_RECRUITING | NA

234 Participants

Speech-to-speech Voice-cloning Care (SVCC) to Improve ICU-acquired Anxiety for Critically Ill Patients

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2026-01-01

Completion: 2026-10-31

Conditions

Critical Care Nursing

Interventions

BEHAVIORAL

No Results Yet

NCT06743256 | RECRUITING | NA

50 Participants

Study Designed to Assess the Safety and Feasibility of the Levita Magnetic Surgical System in Laparoscopic Gynecological Procedures

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2024-12-30

Completion: 2026-05-07

Conditions

Gynecological Laparoscopic Surgery

Interventions

DEVICE

No Results Yet

NCT06737406 | RECRUITING | NA

60 Participants

Topical 5-Fluorouracil (5FU) Plus Calcipotriol in Children With Palmoplantar Wart

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-05-30

Completion: 2026-07-01

Conditions

Common Warts

Interventions

DRUG

No Results Yet

NCT06735924 | RECRUITING | NA

28 Participants

Influence of Metabolic Syndrome on Endogenous Oxalate Synthesis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2023-04-26

Completion: 2026-12-31

Conditions

MASLD Metabolic Dysfunction-Associated Steatotic Liver Disease

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06729177 | COMPLETED | NA

4 Participants

Single Case Research Design: Teacher Outcomes

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2024-08-23

Completion: 2025-07-01

Conditions

Teacher Practice

Interventions

BEHAVIORAL

Results Available

NCT06724809 | ACTIVE_NOT_RECRUITING | PHASE3

21 Participants

Efficacy, Safety, PK, PD, and ADA of Eculizumab in Chinese Adults With NMOSD

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-01-16

Completion: 2026-12-07

Conditions

NMOSD Neuromyelitis Optica Spectrum Disorders

Interventions

DRUG

No Results Yet

NCT06714812 | ACTIVE_NOT_RECRUITING

100 Participants

Diarrheal Adverse Events in Caucasian Patients With Idiopathic Pulmonary Fibrosis Undergoing Treatment With Nintedanib

Study Type: OBSERVATIONAL

Last Updated: 2025-12-19

Start Date: 2023-08-20

Completion: 2023-12-31

Conditions

IPF

No Results Yet

NCT06711224 | RECRUITING | NA

60 Participants

Feasibility Trial of a Guided Internet-delivered Intervention for Adolescents With ADHD

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2024-11-18

Completion: 2027-01-01

Conditions

ADHD

Interventions

BEHAVIORAL

No Results Yet

NCT06710132 | RECRUITING | PHASE1/PHASE2

250 Participants

Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-19

Start Date: 2025-01-29

Completion: 2028-01-26

Conditions

Solid Tumors Gastric Cancer Non-Small Cell Lung Cancer (NSCLC) Pancreatic Cancer Pancreatic Ductal Adenocarcinoma (PDAC)

Interventions

DRUG

No Results Yet