Clinical Trials
Showing trials with last updates posted in 2025.
42
Participants
A Phase II Study to Evaluate the Efficacy and Safety of Anti-HER2 Triple-targeted Drugs Combined With CDK4/6 Inhibitors in Neoadjuvant Therapy for ER-positive HER2-positive Breast Cancer Patients.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2027-10-31
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
120
Participants
Psychological State, Immunotherapy Response, and Multi-Omics Signatures in TNBC
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-01
Completion:
2027-06-30
Conditions
Breast Cancer Female NOS
General Anxiety Disorder
Depressive Disorder
No Results Yet
300
Participants
Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-03-01
Completion:
2028-03-28
Conditions
Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps
Interventions
COMBINATION_PRODUCT
PROCEDURE
No Results Yet
120
Participants
A Computer Game for Postpartum Mental Health After Emergency Cesarean Birth
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-13
Completion:
2026-05-31
Conditions
Post-traumatic Stress Disorder (PTSD)
Postpartum Mental Health
Interventions
BEHAVIORAL
No Results Yet
147
Participants
Mesh-Free Versus Mesh-Based Surgery for Female Stress Urinary Incontinence: A Prospective Comparison of Pubo-Urethral Ligament Plication and Transobturator Tape
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-01-13
Completion:
2026-06-30
Conditions
Stress Urinary Incontinence (SUI)
Interventions
PROCEDURE
No Results Yet
15
Participants
A First-in-Man Clinical Trial to Evaluate the Safety and Feasibility of ICS-Elpis in Patients With Iliac Artery Stenosis or Occlusion Lesions
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-08
Completion:
2027-12-01
Conditions
Iliac Artery Stenosis
Iliac Artery Occlusion
Interventions
DEVICE
No Results Yet
80
Participants
Effect of TECAR on Cervical Radiculopathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-01
Completion:
2026-03-05
Conditions
Cervical Radiculopathy
Interventions
DEVICE
No Results Yet
80
Participants
Circulating microRNAs and Response to Neoadjuvant Chemotherapy in Breast Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-15
Completion:
2026-08-31
Conditions
Breast Cancer
Neoadjuvant Therapy
Pathological Response
Invasive Breast Carcinoma
MicroRNAs
No Results Yet
100
Participants
Terazosin And Metabolic Engagement in Parkinson's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-09-01
Completion:
2030-09-01
Conditions
Parkinson's Disease
Interventions
DRUG
OTHER
No Results Yet
[Trial of device that is not approved or cleared by the U.S. FDA]
Last Updated:
2025-12-18
No Results Yet
33
Participants
The Effect of Mulligan and GMI on Distal Radius Proprioception
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-11-01
Completion:
2026-08-15
Conditions
Distal Radial Fracture
Rehabilitation
Mulligan Mobilization
Motor Imagery Training
Physical Therapy
Interventions
OTHER
No Results Yet
60
Participants
Parcel-guided rTMS for Major Depressive Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-15
Completion:
2028-06-01
Conditions
Treatment Resistant Depression (TRD)
Interventions
DEVICE
No Results Yet
92
Participants
Effect of Fluoride Varnish Formulation on the Management of Dentin Hypersensitivity
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-04
Completion:
2026-05-29
Conditions
Fluoride Varnishes
Hypersensitivity Dentin
Interventions
DEVICE
No Results Yet
24
Participants
A Study Of Effect Of Secretin For In Injection (Chirostim) On Pancreatic Fluid Composition In Healthy Subjects
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-31
Completion:
2027-01-31
Conditions
Exocrine Pancreatic Insufficiency
Chronic Pancreatitis
Interventions
DRUG
No Results Yet
230
Participants
Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-10
Completion:
2027-04-20
Conditions
Clostridioides Difficile Infection
Interventions
DRUG
OTHER
No Results Yet
1200
Participants
Efficacy and Safety of KAI-9531 Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2028-03-20
Conditions
Obesity
Interventions
DRUG
No Results Yet
1700
Participants
Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2028-03-27
Conditions
Obesity With Diabetes
Overweight With Diabetes
Interventions
DRUG
No Results Yet
1800
Participants
Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2028-02-28
Conditions
Obesity
Overweight
Interventions
DRUG
No Results Yet
700
Participants
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-02-16
Completion:
2028-12-29
Conditions
CRC (Colorectal Cancer)
Interventions
DRUG
No Results Yet
10
Participants
Safety and Usability of the Cionic Neural Sleeve for Parkinson's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2026-12-31
Conditions
Parkinson Disease (PD)
Interventions
DEVICE
No Results Yet
144
Participants
Multimodal Deep Learning for Postoperative Liver Cancer Risk Stratification and Intervention
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-10-26
Completion:
2027-06-30
Conditions
Hepotacellular Carcinoma
Interventions
OTHER
PROCEDURE
COMBINATION_PRODUCT
No Results Yet
213
Participants
Does Implementation of Feedback Informed Therapy (FIT) Improve Access to Psychotherapy in Psychiatry?
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2024-09-01
Completion:
2025-11-30
Conditions
Psychiatric Diagnosis
Interventions
BEHAVIORAL
No Results Yet
25
Participants
Regenarative Treatment of Periocular Wrinkles With PDRN
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-11-30
Completion:
2026-03-30
Conditions
Skin Wrinklings
Interventions
PROCEDURE
No Results Yet
66
Participants
Duraplasty for Acute Traumatic Spinal Cord Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-31
Completion:
2029-06-30
Conditions
Spinal Cord Injury, Acute
Spinal Cord Injury (SCI), Initial Encounter
Spinal Cord Injury Cervical
Interventions
PROCEDURE
No Results Yet
40
Participants
Effects of Platelet and Leukocyte-rich Fibrin on Alveolar Ridge Maintenance Through Three-dimensional Analysis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2016-01-20
Completion:
2018-02-20
Conditions
Caries Active
Tooth Decay
Tooth Loss / Rehabilitation
Interventions
PROCEDURE
No Results Yet
60
Participants
Role of the Microbiota in Obesity: Effect After Bariatric Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-03-03
Completion:
2025-01-31
Conditions
Obese Patients With Bariatric Surgery
Interventions
PROCEDURE
No Results Yet
40
Participants
An Evaluation of the Omnipod® M System in Adults With Type 2 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-12
Completion:
2026-02-27
Conditions
Type 2 Diabetes Mellitus
Interventions
DEVICE
No Results Yet
128
Participants
The Effect of Nada Yoga Music and Stress Ball Use on Anxiety and Pain Levels
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-04-01
Completion:
2025-07-30
Conditions
Intervention Effectiveness
Interventions
OTHER
No Results Yet
320
Participants
A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-15
Completion:
2027-11-12
Conditions
Rheumatoid Arthritis
Interventions
DRUG
OTHER
No Results Yet
40
Participants
Early and Long-Term Efficacy and Immune Changes With Dupilumab in Prurigo Nodularis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-06-01
Completion:
2028-06-01
Conditions
Prurigo Nodularis (PN)
Interventions
DRUG
No Results Yet
22
Participants
Plasma Oxytocin Changes in Response to Music Modified by Sonic Augmentation Technology
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2026-08-31
Conditions
Sonic Augmentation Technology
Interventions
OTHER
No Results Yet
20
Participants
Multi-strain Probiotic Effects on Self-Reported Constipation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-10-03
Completion:
2026-04-30
Conditions
Constipation
Probiotic
Probiotic Intervention
Interventions
DIETARY_SUPPLEMENT
No Results Yet
18
Participants
A Study of CNCT19 in the Treatment of Relapsed or Refractory Neurological Autoimmune Diseases
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-15
Completion:
2027-06-01
Conditions
Neurological Autoimmune Diseases
Interventions
BIOLOGICAL
No Results Yet
3000
Participants
A Clinical Trial of Rabies Vaccine（Human Diploid Cell）for Human Use,Freeze-dried in a Population Aged 10 to 60 Years
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-18
Completion:
2026-02-18
Conditions
Rabies
Interventions
BIOLOGICAL
No Results Yet
192
Participants
DIROXIMEL FUMARATE TO REDUCE PERIHAEMATOMAL OEDEMA IN INTRACEREBRAL HAEMORRHAGE: DOUBLE BLIND RANDOMIZED CLINICAL TRIAL
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-02-01
Completion:
2029-03-31
Conditions
Stroke
Interventions
DRUG
No Results Yet
344
Participants
Effectiveness and Safety of Uptitration of Guideline Directed MEdical Therapy in Heart Failure With Reduced Ejection Fraction With Limited Kidney Function Assessments
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-04-01
Completion:
2030-01-01
Conditions
Heart Failure
Heart Failure and Reduced Ejection Fraction
Heart Failure and Mildly Reduced Ejection Fraction
Interventions
OTHER
No Results Yet
1000
Participants
Human Papillomavirus Self-sampling for Enhancing Cervical Screening During the War in Ukraine
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-04-01
Completion:
2026-08-31
Conditions
Cervical Cancer
Cervical Cancer Screening
Human Papillomavirus (HPV) Infection
Cervical Intraepithelial Neoplasia
Interventions
DEVICE
No Results Yet
100
Participants
Repeatable Evaluation of Functional Intra-procedural Signals for Effect in Pulsed Field Ablation REFINE-PFA
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-25
Completion:
2026-07-31
Conditions
Atrial Fibrillation
Interventions
DEVICE
No Results Yet
200
Participants
JMT106 Injection in the Treatment of Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-09-25
Completion:
2026-11-05
Conditions
Advanced Solid Tumor
Lung Squamous Cell Carcinoma
Hepatocellular Carcinoma
Interventions
DRUG
No Results Yet
80
Participants
Mindfulness-Based Stress Reduction for Adolescents: Effects on Game Addiction, Stress, and Sleep
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-11-03
Completion:
2025-11-10
Conditions
Adolescent Behaviour Disorder
Stress Reduction
Sleep Quality
Digital Addiction
Interventions
BEHAVIORAL
No Results Yet
Showing 40 trials per page