Clinical Trials Updated in 2025

NCT06958211 | RECRUITING | PHASE3

450 Participants

Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-06-12

Completion: 2026-10-09

Conditions

Hidradenitis Suppurativa

Interventions

DRUG

No Results Yet

NCT06953583 | RECRUITING | PHASE3

255 Participants

A Study to Learn More About the Effects and Long-Term Safety of BIIB141 (Omaveloxolone) in Participants With Friedreich's Ataxia Aged 2 to 15 Years Old (BRAVE)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-06-09

Completion: 2027-11-16

Conditions

Friedreich Ataxia

Interventions

DRUG

No Results Yet

NCT06948318 | RECRUITING | PHASE3

150 Participants

A Continuation Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-08-14

Completion: 2029-07-29

Conditions

Immune Thrombocytopenic Purpura (ITP)

Interventions

DRUG

No Results Yet

NCT06946303 | COMPLETED

24 Participants

Identifying Key Attributes and Learning From a Local Falls Prevention Ambassador Programme

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2024-08-13

Completion: 2025-09-30

Conditions

Long Term Care

Interventions

OTHER

No Results Yet

NCT06942936 | ACTIVE_NOT_RECRUITING | PHASE1

51 Participants

A Study to Investigate the Impact of Multiple Doses of Itraconazole on AZD5004 in Healthy Participants and Multiple Doses of AZD5004 on Combined Oral Ethinyl Oestradiol and Levonorgestrel in Healthy Female Participants

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-05-28

Completion: 2026-01-28

Conditions

Healthy Participants

Interventions

DRUG

No Results Yet

NCT06942039 | RECRUITING | EARLY_PHASE1

15 Participants

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-09-23

Completion: 2030-12-31

Conditions

CNS Embryonal Tumor CNS, Medulloblastoma Atypical Teratoid Rhabdoid Tumor Medulloblastoma, Childhood Medulloblastoma, Group 3 Medulloblastoma, Group 4 Pineoblastoma Neuroblastoma Embryonal Tumor With Multilayered Rosettes Embryonal Tumor With Abundant Neuropil and True Rosettes Ependymoblastoma Medulloepithelioma CNS Embryonal Tumor With Rhabdoid Features CNS Embryonal Tumor, Nos

Interventions

DRUG

No Results Yet

NCT06941324 | RECRUITING | NA

60 Participants

Solution-Focused Brief Therapy for Support of Psychological Distress in Adolescent and Young Adult Cancer Survivors

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2026-01-01

Completion: 2028-07-01

Conditions

Hematopoietic and Lymphatic System Neoplasm Malignant Solid Neoplasm

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT06940713 | RECRUITING | NA

76 Participants

Prospective Study of the Feasibility of Brain Connectivity Imaging by Functional Ultrasound Imaging (fUS) in Newborn Infant

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-11-28

Completion: 2030-04-30

Conditions

Neonates and Preterm Infants Neonates or Premature Babies

Interventions

DEVICE

No Results Yet

NCT06938802 | COMPLETED | NA

40 Participants

Pilot Study of App-delivered Sleep Coaching Among Cancer Survivors and Their Partners

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-07-21

Completion: 2025-12-16

Conditions

Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06938607 | NOT_YET_RECRUITING

360 Participants

Post-operative Outcomes of Anterior Cervical Discectomy and Fusion Surgery With and Without Drain Placement

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2026-02-28

Completion: 2028-04-30

Conditions

ACDF Surgery

Interventions

DEVICE

No Results Yet

NCT06933095 | RECRUITING | NA

153 Participants

Optimizing CNS DHA Delivery in Elderly Adults at Risk for Dementia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-09-15

Completion: 2029-09-15

Conditions

Eldery People Cognitive Decline Memory Decline DHA CNS Delivery

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06931717 | RECRUITING | PHASE3

390 Participants

A Clinical Study to Assess the Efficacy of Adjuvant Immunotherapy With Cemiplimab in Patients With Surgically Removed Non-small Cell Lung Cancer Who Have Not Received Prior Chemotherapy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2026-01-31

Completion: 2029-03-31

Conditions

Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT06931665 | RECRUITING | NA

26 Participants

Neurological and Physiological Effects of Animal-assisted Therapy for Patients in a Minimally Conscious State

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-07-08

Completion: 2027-04-30

Conditions

Minimally Conscious State

Interventions

PROCEDURE

No Results Yet

NCT06927310 | RECRUITING | PHASE3

300 Participants

The Efficacy and Safety of Inpegsomatropin Injection in Children With Idiopathic Short Stature

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-04-28

Completion: 2026-03-31

Conditions

Idiopathic Short Stature

Interventions

DRUG

No Results Yet

NCT06925360 | RECRUITING | PHASE2

14 Participants

IVIG Trial for the Treatment of Bronchopulmonary Dysplasia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-04-12

Completion: 2027-12-31

Conditions

Bronchopulmonary Dysplasia

Interventions

DRUG

No Results Yet

NCT06924801 | RECRUITING | NA

30 Participants

Integration of Real-Time Motion Tracking and Pediatric Rehabilitation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-10-15

Completion: 2026-09-30

Conditions

Rehabilitation

Interventions

BEHAVIORAL

No Results Yet

NCT06923813 | RECRUITING | NA

20 Participants

Assessment of Nutrient Absorption in Enterally Fed Post-intensive Care Unit Patients Using Bomb Calorimetry: do the Calories Stick

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2026-01-01

Completion: 2026-04-01

Conditions

Post-ICU Patients Fully Enterally Fed

Interventions

OTHER PROCEDURE

No Results Yet

NCT06922669 | RECRUITING | NA

232 Participants

Glucocorticoids for Acute Drug Induced Liver Injury With Hyperbilirubinemia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-06-24

Completion: 2027-03-31

Conditions

Drug Induced Liver Injury

Interventions

DRUG PROCEDURE

No Results Yet

NCT06919939 | RECRUITING | PHASE2

26 Participants

Epcoritamab in Combination With Loncastuximab Tesirine in Relapsed/Refractory Large B-cell Lymphoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2026-02-01

Completion: 2031-02-01

Conditions

Large B-cell Lymphoma Relapse

Interventions

DRUG

No Results Yet

NCT06919900 | RECRUITING | NA

64 Participants

Motor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple Sclerosis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2026-01-31

Completion: 2028-03-31

Conditions

Multiple Sclerosis (Relapsing Remitting)

Interventions

BEHAVIORAL

No Results Yet

NCT06917378 | RECRUITING

5000 Participants

TRIO CTO (Taiwan Research Initiative on Coronary Total Occlusion)

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2017-01-01

Completion: 2034-12-31

Conditions

Chronic Total Occlusion (CTO)

Interventions

PROCEDURE

No Results Yet

NCT06915233 | RECRUITING | PHASE3

309 Participants

A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-12-31

Completion: 2030-07-31

Conditions

Chondral Defect Articular Cartilage Defect

Interventions

BIOLOGICAL PROCEDURE

No Results Yet

NCT06915090 | COMPLETED | NA

15 Participants

FIT-COACH: Fitbit Intervention With Coordinated Health Coaching and PCP Support

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-03-18

Completion: 2025-09-30

Conditions

GLP - 1 Diabetes Obesity and Obesity-related Medical Conditions Cardiovascular Diseases

Interventions

BEHAVIORAL

No Results Yet

NCT06914622 | RECRUITING | NA

72 Participants

Real-time Experiences, Physical Activity and Biological Outcomes in Personal Recovery Residents (EMPOWER-RES)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2026-01-15

Completion: 2027-12-31

Conditions

Severe Mental Disorder Severe Mental Illness

Interventions

BEHAVIORAL

No Results Yet

NCT06910384 | TERMINATED | PHASE2

1 Participants

A Study of STRO4 in Patients Amyotrophic Lateral Sclerosis (ALS)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-08-12

Completion: 2025-12-16

Conditions

Amyotrophic Lateral Sclerosis

Interventions

BIOLOGICAL

No Results Yet

NCT06905392 | RECRUITING

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2025-10-02

Completion: 2025-11-10

Conditions

Hip Injuries and Disorders

No Results Yet

NCT06850051 | ACTIVE_NOT_RECRUITING | PHASE1

270 Participants

A Study on the Safety and Immunogenicity of Influenza, Respiratory Syncytial Virus, Human Metapneumovirus and Parainfluenza Vaccines in Adults 18 to 49 Years of Age.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-03-19

Completion: 2026-01-31

Conditions

Healthy Volunteers Influenza Vaccination Respiratory Syncytial Virus Vaccination Parainfluenza Vaccination Human Metapneumovirus Vaccination

Interventions

BIOLOGICAL

No Results Yet

NCT06847646 | COMPLETED | NA

74 Participants

Evaluation of Bioflex Crowns Using the Hall Technique in Primary Molars

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-08-20

Completion: 2025-08-20

Conditions

BioFlex Crowns Using Hall Technique

Interventions

OTHER

No Results Yet

NCT06842654 | RECRUITING

20 Participants

EORTC Quality of Life Measurement Strategies in Progressive Cancer

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2025-08-13

Completion: 2026-03-31

Conditions

Cancer

No Results Yet

NCT06840288 | RECRUITING

250 Participants

Bronchoscopic Lung Ablation of Small Thoracic Tumors: the Blastt Registry

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2025-02-19

Completion: 2034-12-31

Conditions

Thoracic Tumors

No Results Yet

NCT06837662 | RECRUITING | NA

70 Participants

The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Disorder Seen In Primary Care

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-03-24

Completion: 2026-03-21

Conditions

Opioid Dependence Substance Abuse Disorders Complex Medical Patients Primary Care Patients With Chronic Conditions

Interventions

BEHAVIORAL

No Results Yet