Clinical Trials
Showing trials with last updates posted in 2025.
5000
Participants
TRIO CTO (Taiwan Research Initiative on Coronary Total Occlusion)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2017-01-01
Completion:
2034-12-31
Conditions
Chronic Total Occlusion (CTO)
Interventions
PROCEDURE
No Results Yet
309
Participants
A Study of MACI in Patients Aged 17 to 65 Years With Symptomatic Chondral or Osteochondral Defects of the Ankle
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-31
Completion:
2030-07-31
Conditions
Chondral Defect
Articular Cartilage Defect
Interventions
BIOLOGICAL
PROCEDURE
No Results Yet
15
Participants
FIT-COACH: Fitbit Intervention With Coordinated Health Coaching and PCP Support
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-03-18
Completion:
2025-09-30
Conditions
GLP - 1
Diabetes
Obesity and Obesity-related Medical Conditions
Cardiovascular Diseases
Interventions
BEHAVIORAL
No Results Yet
72
Participants
Real-time Experiences, Physical Activity and Biological Outcomes in Personal Recovery Residents (EMPOWER-RES)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-15
Completion:
2027-12-31
Conditions
Severe Mental Disorder
Severe Mental Illness
Interventions
BEHAVIORAL
No Results Yet
1
Participants
A Study of STRO4 in Patients Amyotrophic Lateral Sclerosis (ALS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-08-12
Completion:
2025-12-16
Conditions
Amyotrophic Lateral Sclerosis
Interventions
BIOLOGICAL
No Results Yet
100
Participants
AQT90 FLEX NTproBNP2 Test Kit Matrix Comparison and Sample Stability Verification Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-05-15
Completion:
2025-12-31
Conditions
Diagnostic Tests
No Results Yet
61
Participants
Ontegimod and Gemcitabine/Nab-paclitaxel as Second Line Therapy for Metastatic Pancreatic Ductal Adenocarcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-30
Completion:
2028-07-31
Conditions
Metastatic Pancreatic Ductal Adenocarcinoma
Interventions
DRUG
No Results Yet
3000
Participants
Optimizing Health Related Quality of Life Measurement in Adolescent and Young Adult Oncology
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-31
Completion:
2028-01-31
Conditions
Malignant Solid Neoplasm
Hematopoietic Neoplasms
Lymphatic System Neoplasm
Interventions
OTHER
No Results Yet
100
Participants
Five PLus Year EffIcacy of Endoscopic Sleeve Gastroplasty (ESG) for Sustained WeigHT Loss
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-31
Completion:
2026-10-31
Conditions
Obesity and Obesity-related Medical Conditions
Weight Loss
Interventions
OTHER
No Results Yet
140
Participants
STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable Hepatocellular Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-10-21
Completion:
2028-01-31
Conditions
Hepatocellular Carcinoma
Interventions
DRUG
No Results Yet
132
Participants
Omnipod® SmartAdjust 2.0 System Compared to the Omnipod® 5 System in Individuals With Type 1 or Type 2 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-03-26
Completion:
2025-11-10
Conditions
Diabetes Mellitus, Type 1, Type 2
Interventions
DEVICE
No Results Yet
120
Participants
Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-04-11
Completion:
2027-12-31
Conditions
Psoriatic Arthritis
Interventions
DRUG
No Results Yet
100
Participants
Continuous Glucose Monitoring in Patients Undergoing Cardiopulmonary Bypass
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-31
Completion:
2026-10-31
Conditions
Glucose Metabolism Disorders (Including Diabetes Mellitus)
Interventions
DEVICE
No Results Yet
1180
Participants
Surgical vs Transcatheter Aortic Valve Replacement in Young Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-05-15
Completion:
2027-11-30
Conditions
Symptomatic Severe Aortic Stenosis
Interventions
DEVICE
No Results Yet
110
Participants
Investigating Postural Parameters in Different Hip Pathologies
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-10-02
Completion:
2025-11-10
Conditions
Hip Injuries and Disorders
No Results Yet
74
Participants
Evaluation of Bioflex Crowns Using the Hall Technique in Primary Molars
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2024-08-20
Completion:
2025-08-20
Conditions
BioFlex Crowns Using Hall Technique
Interventions
OTHER
No Results Yet
20
Participants
EORTC Quality of Life Measurement Strategies in Progressive Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-08-13
Completion:
2026-03-31
Conditions
Cancer
No Results Yet
250
Participants
Bronchoscopic Lung Ablation of Small Thoracic Tumors: the Blastt Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-02-19
Completion:
2034-12-31
Conditions
Thoracic Tumors
No Results Yet
70
Participants
The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Disorder Seen In Primary Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-03-24
Completion:
2026-03-21
Conditions
Opioid Dependence
Substance Abuse Disorders
Complex Medical Patients
Primary Care Patients With Chronic Conditions
Interventions
BEHAVIORAL
No Results Yet
12
Participants
Extension Study of Participants From SPG302-ALZ-101
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-03-25
Completion:
2025-07-30
Conditions
Alzheimer's Disease
Interventions
DRUG
No Results Yet
240
Participants
A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-06-17
Completion:
2026-07-13
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
23
Participants
Subcutaneous Talquetamab in Elderly Patients With Multiple Myeloma in Early Relapse
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-11-18
Completion:
2027-01-31
Conditions
Multiple Myeloma in Relapse
Interventions
DRUG
No Results Yet
60
Participants
A Ph Ib Study of REGN5678 Plus Cemiplimab in Patients With mCRPC
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-07-09
Completion:
2027-05-01
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
194
Participants
Clinical Studies for the Treatment of Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-04-08
Completion:
2026-03-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
30
Participants
Assessment of Acupuncture on Eye Fatigue
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2024-08-01
Completion:
2024-12-30
Conditions
Acupuncture
Eye Fatigue
Accomodation
Interventions
DEVICE
No Results Yet
682
Participants
A Multilevel Intervention to Increase Colorectal Cancer Screening Tests in Patients With Abnormal Fecal Immunochemical Test Results, PROACT Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-12-16
Completion:
2028-06-30
Conditions
Colorectal Carcinoma
Interventions
OTHER
No Results Yet
238
Participants
Study Comparing Safety and Immunogenicity of Intranasal COVID-19 Vaccine and mRNA Booster in Healthy Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-05-09
Completion:
2026-10-31
Conditions
Healthy
Interventions
BIOLOGICAL
No Results Yet
214
Participants
Opportunistic Pneumococcal Immunisation Trial in MALnutrition
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-01-31
Completion:
2028-03-31
Conditions
Severe Acute Malnutrition in Childhood
Pneumococcal Disease
Pneumococcal Vaccines
Pneumococcal Infection
Pneumonia in Children
Interventions
BIOLOGICAL
No Results Yet
321
Participants
A Safety and Tolerability Study of VRDN-003 in Participants With Thyroid Eye Disease (TED)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-02-03
Completion:
2026-04-30
Conditions
Thyroid Eye Disease (TED)
Interventions
DRUG
No Results Yet
60
Participants
COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-01-24
Completion:
2026-04-30
Conditions
Total Knee Anthroplasty
Osteoarthritis(Primary)
Osteoarthritis (OA) of the Knee
Bilateral Knee Osteoarthritis
Interventions
DRUG
OTHER
No Results Yet
43
Participants
Photodynamic Therapy of Primary Localized Prostate Cancer With the SpectraCure P18 System
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-01-06
Completion:
2028-01-31
Conditions
Prostate Cancer
Interventions
DEVICE
DRUG
No Results Yet
50
Participants
Trauma-informed, Resilience-based Telehealth Intervention for Improving HIV Prevention and HCV Care for Persons Who Inject Drugs in the Deep South (Pilot Testing: Aim3)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-08-01
Completion:
2028-03-31
Conditions
HIV Pre-exposure Prophylaxis
HEPATITIS C (HCV)
Opioid Use Disorder
Interventions
BEHAVIORAL
No Results Yet
156
Participants
Tributyrin Treatment in Mild Alzheimer Disease: Assessment of Butyrate Effects Via the Gut-Brain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2026-06-01
Completion:
2026-09-01
Conditions
Alzheimer Disease (AD)
Interventions
DIETARY_SUPPLEMENT
OTHER
No Results Yet
115
Participants
A Study of PT0253 in Participants With KRAS G12D Mutated Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2024-12-19
Completion:
2026-12-15
Conditions
Solid Tumor
Interventions
DRUG
No Results Yet
600
Participants
A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-10-24
Completion:
2028-11-30
Conditions
Non-Small Cell Lung Cancer
KRAS G12C Lung Cancer
Interventions
DRUG
No Results Yet
9
Participants
Pharmacokinetics, Pharmacodynamics, Safety, and Preliminary Efficacy of Subcutaneous Injection of SHR-1905 in Adolescent Asthmatic Subjects - an Open-label, Single-dose Phase II Clinical Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-01-23
Completion:
2025-12-03
Conditions
Adolescent Asthma
Interventions
DRUG
No Results Yet
192
Participants
Magnesium Trial in Acute Asthma in Emergency Department
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-10-08
Completion:
2027-10-31
Conditions
Asthma
Interventions
DRUG
No Results Yet
270
Participants
Impact of Video-Based Pressure Injury Training on Caregivers' Knowledge, Attitudes, Behaviors & Reactions
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2024-01-14
Completion:
2024-12-14
Conditions
Pressure Injury
Interventions
BEHAVIORAL
No Results Yet
100
Participants
Prospective Registry of ADC as First- and Second-line Treatment for Breast Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2025-10-08
Completion:
2030-12-31
Conditions
HER2-negative Breast Cancer
HER2 Negative Breast Carcinoma
Metastatic Breast Cancer
HR+ HER2 Breast Cancer
Metastatic Triple Negative Breast Cancers
Metastatic Triple-Negative Breast Carcinoma
Interventions
PROCEDURE
DRUG
OTHER
No Results Yet
20
Participants
A Phase 1 Study of Y-3 in US Healthy Volunteers.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-02-04
Completion:
2025-09-20
Conditions
Safety
Tolerability
Pharmacokinetic Study in Healthy Volunteers
Interventions
DRUG
No Results Yet
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