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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06833281 | TERMINATED | PHASE2
12 Participants

Extension Study of Participants From SPG302-ALZ-101

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-03-25
Completion: 2025-07-30
Conditions
Alzheimer's Disease
Interventions
DRUG
No Results Yet
NCT06832618 | RECRUITING | PHASE3
240 Participants

A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-06-17
Completion: 2026-07-13
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
NCT06827860 | RECRUITING | PHASE2
23 Participants

Subcutaneous Talquetamab in Elderly Patients With Multiple Myeloma in Early Relapse

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-11-18
Completion: 2027-01-31
Conditions
Multiple Myeloma in Relapse
Interventions
DRUG
No Results Yet
NCT06826768 | RECRUITING | PHASE1
60 Participants

A Ph Ib Study of REGN5678 Plus Cemiplimab in Patients With mCRPC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-07-09
Completion: 2027-05-01
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06825494 | RECRUITING | PHASE1/PHASE2
194 Participants

Clinical Studies for the Treatment of Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-04-08
Completion: 2026-03-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT06823388 | COMPLETED | NA
30 Participants

Assessment of Acupuncture on Eye Fatigue

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-08-01
Completion: 2024-12-30
Conditions
Acupuncture Eye Fatigue Accomodation
Interventions
DEVICE
No Results Yet
NCT06822530 | ENROLLING_BY_INVITATION | NA
682 Participants

A Multilevel Intervention to Increase Colorectal Cancer Screening Tests in Patients With Abnormal Fecal Immunochemical Test Results, PROACT Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-12-16
Completion: 2028-06-30
Conditions
Colorectal Carcinoma
Interventions
OTHER
No Results Yet
NCT06821126 | RECRUITING | PHASE1/PHASE2
238 Participants

Study Comparing Safety and Immunogenicity of Intranasal COVID-19 Vaccine and mRNA Booster in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-05-09
Completion: 2026-10-31
Conditions
Healthy
Interventions
BIOLOGICAL
No Results Yet
NCT06817421 | NOT_YET_RECRUITING | PHASE4
214 Participants

Opportunistic Pneumococcal Immunisation Trial in MALnutrition

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-01-31
Completion: 2028-03-31
Conditions
Severe Acute Malnutrition in Childhood Pneumococcal Disease Pneumococcal Vaccines Pneumococcal Infection Pneumonia in Children
Interventions
BIOLOGICAL
No Results Yet
NCT06812325 | ACTIVE_NOT_RECRUITING | PHASE3
321 Participants

A Safety and Tolerability Study of VRDN-003 in Participants With Thyroid Eye Disease (TED)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-02-03
Completion: 2026-04-30
Conditions
Thyroid Eye Disease (TED)
Interventions
DRUG
No Results Yet
NCT06809998 | RECRUITING | PHASE1/PHASE2
60 Participants

COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-24
Completion: 2026-04-30
Conditions
Total Knee Anthroplasty Osteoarthritis(Primary) Osteoarthritis (OA) of the Knee Bilateral Knee Osteoarthritis
Interventions
DRUG OTHER
No Results Yet
NCT06807359 | RECRUITING | PHASE1/PHASE2
43 Participants

Photodynamic Therapy of Primary Localized Prostate Cancer With the SpectraCure P18 System

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-06
Completion: 2028-01-31
Conditions
Prostate Cancer
Interventions
DEVICE DRUG
No Results Yet
NCT06799702 | NOT_YET_RECRUITING | NA
50 Participants

Trauma-informed, Resilience-based Telehealth Intervention for Improving HIV Prevention and HCV Care for Persons Who Inject Drugs in the Deep South (Pilot Testing: Aim3)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-08-01
Completion: 2028-03-31
Conditions
HIV Pre-exposure Prophylaxis HEPATITIS C (HCV) Opioid Use Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06797817 | NOT_YET_RECRUITING | PHASE3
156 Participants

Tributyrin Treatment in Mild Alzheimer Disease: Assessment of Butyrate Effects Via the Gut-Brain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-06-01
Completion: 2026-09-01
Conditions
Alzheimer Disease (AD)
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT06797336 | RECRUITING | PHASE1
115 Participants

A Study of PT0253 in Participants With KRAS G12D Mutated Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-19
Completion: 2026-12-15
Conditions
Solid Tumor
Interventions
DRUG
No Results Yet
NCT06793215 | RECRUITING | PHASE3
600 Participants

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-10-24
Completion: 2028-11-30
Conditions
Non-Small Cell Lung Cancer KRAS G12C Lung Cancer
Interventions
DRUG
No Results Yet
NCT06786455 | COMPLETED | PHASE2
9 Participants

Pharmacokinetics, Pharmacodynamics, Safety, and Preliminary Efficacy of Subcutaneous Injection of SHR-1905 in Adolescent Asthmatic Subjects - an Open-label, Single-dose Phase II Clinical Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-23
Completion: 2025-12-03
Conditions
Adolescent Asthma
Interventions
DRUG
No Results Yet
NCT06785272 | RECRUITING | PHASE3
192 Participants

Magnesium Trial in Acute Asthma in Emergency Department

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-10-08
Completion: 2027-10-31
Conditions
Asthma
Interventions
DRUG
No Results Yet
NCT06775171 | COMPLETED | NA
270 Participants

Impact of Video-Based Pressure Injury Training on Caregivers' Knowledge, Attitudes, Behaviors & Reactions

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-01-14
Completion: 2024-12-14
Conditions
Pressure Injury
Interventions
BEHAVIORAL
No Results Yet
NCT06774027 | RECRUITING
100 Participants

Prospective Registry of ADC as First- and Second-line Treatment for Breast Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2025-10-08
Completion: 2030-12-31
Conditions
HER2-negative Breast Cancer HER2 Negative Breast Carcinoma Metastatic Breast Cancer HR+ HER2 Breast Cancer Metastatic Triple Negative Breast Cancers Metastatic Triple-Negative Breast Carcinoma
Interventions
PROCEDURE DRUG OTHER
No Results Yet
NCT06770491 | COMPLETED | PHASE1
20 Participants

A Phase 1 Study of Y-3 in US Healthy Volunteers.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-02-04
Completion: 2025-09-20
Conditions
Safety Tolerability Pharmacokinetic Study in Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT06768983 | COMPLETED | NA
5 Participants

Fatigue Reduction in Chronic Kidney Disease (CKD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-30
Completion: 2025-09-16
Conditions
Chronic Kidney Diseases Fatigue
Interventions
BEHAVIORAL
No Results Yet
NCT06761586 | RECRUITING | PHASE1
42 Participants

A Study of AUR104 in Patients With Relapsed/Refractory Lymphoid Malignancies (VIJAY-1)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-12
Completion: 2026-11-04
Conditions
Select Relapsed/Refractory Lymphoid Malignancies
Interventions
DRUG
No Results Yet
NCT06748898 | COMPLETED | NA
60 Participants

Effect of Transcutaneous Electrical Nerve Stimulation Based on Wrist-ankle Acupuncture Theory on EC50 of Remifentanil Inhibiting Responses to Tracheal Intubation Under General Anesthesia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-02-06
Completion: 2025-11-14
Conditions
Perioperative Analgesia General Anaesthesia
Interventions
OTHER
No Results Yet
NCT06741514 | ENROLLING_BY_INVITATION
100 Participants

A Study of Precice Intramedullary Limb Lengthening System (IMLL) Limb Lengthening Procedures

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2024-03-25
Completion: 2026-07-01
Conditions
Limb Length Discrepancy
Interventions
DEVICE
No Results Yet
NCT06739122 | RECRUITING | PHASE3
55 Participants

A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-10
Completion: 2026-06-30
Conditions
Type 2 Diabetes
Interventions
DRUG
No Results Yet
NCT06736613 | RECRUITING | PHASE2
50 Participants

A Study of Circulating Tumor DNA (ctDNA) Testing for People With B-Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-11
Completion: 2027-12-11
Conditions
Diffuse Large B Cell Lymphoma High-grade B-cell Lymphoma Stage III High Grade B-Cell Lymphoma Stage IV High Grade B-Cell Lymphoma DLBCL - Diffuse Large B Cell Lymphoma Intravascular Large B-Cell Lymphoma Diffuse Large B Cell Lymphoma of Breast Diffuse Large B Cell Lymphoma of Testis HIV-associated Diffuse Large B Cell Lymphoma Double Expressor DLBCL
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06736028 | RECRUITING | NA
20 Participants

Ketogenic Diets for Weight Loss Maintenance: Impact on Energy Expenditure and Appetite in Individuals With Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-08-01
Completion: 2026-06-30
Conditions
Obesity
Interventions
BEHAVIORAL
No Results Yet
NCT06733675 | RECRUITING | PHASE1
46 Participants

Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-07
Completion: 2026-06-30
Conditions
Healthy Volunteer Pharmacokinetics Safety Drug-Drug Interaction (DDI) FDC
Interventions
DRUG
No Results Yet
NCT06729957 | RECRUITING | NA
360 Participants

Addressing Barriers to Care for Substance Use Disorder Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-16
Completion: 2026-08-21
Conditions
Drug Use Disorders Alcohol-Related Disorders Substance Use Disorder (SUD)
Interventions
BEHAVIORAL
No Results Yet
NCT06727812 | RECRUITING | PHASE1
206 Participants

Multicenter Phase I Study of HRS-6208 in Patients With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-17
Completion: 2027-08-31
Conditions
Solid Tumors
Interventions
DRUG
No Results Yet
NCT06724913 | ACTIVE_NOT_RECRUITING | NA
100 Participants

Efficacy and Tolerability of a Specialized Food Products for Dietary Therapeutic and Preventive Nutrition Based on Ice Cream (Ice Cream With Brazzein, Maltitol and Oligofructose; Ice Cream With Brazzein, Erythritol, Maltitol and Inulin) Compared to Standard (Sundae) Ice Cream

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-06-01
Completion: 2025-12-31
Conditions
Non-Alcoholic Steatohepatitis (NASH) Diabetes Mellitus Type 2 (T2DM)
Interventions
OTHER
No Results Yet
NCT06722378 | RECRUITING | NA
630 Participants

A Trial to Improve Family Clinical Note Access and Outcomes for Hospitalized Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-04-01
Completion: 2029-04-30
Conditions
Hospitalized Child Pediatric Patient Safety Medical Errors Parental Engagement in Care Inpatient Pediatric Care
Interventions
OTHER
No Results Yet
NCT06722235 | RECRUITING | PHASE3
171 Participants

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-02-27
Completion: 2027-12-28
Conditions
Immune Thrombocytopenic Purpura (ITP)
Interventions
DRUG
No Results Yet
NCT06720519 | COMPLETED
170 Participants

Molecular Panel Evaluation for Diagnosis of Infections of the Central Nervosous System

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2024-04-17
Completion: 2024-10-17
Conditions
Infections Nervous System
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06719921 | RECRUITING | NA
724 Participants

Catheter Ablation for Atrial Fibrillation in Non-Fluoroscopic Lab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-04-22
Completion: 2028-04-30
Conditions
Atrial Fibrillation (AF)
Interventions
PROCEDURE OTHER
No Results Yet
NCT06717867 | RECRUITING | PHASE2
200 Participants

Long-Term PEA Safety Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-22
Completion: 2027-06-30
Conditions
Safety Healthy
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT06715462 | WITHDRAWN | PHASE3
0 Participants

Efficacy and Safety of the N0750 Compared to Monotherapies in the Treatment of Painful Diabetic Peripheral Neuropathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-04-30
Completion: 2028-03-31
Conditions
Painful Diabetic Peripheral Neuropathy (PDPN)
Interventions
DRUG
No Results Yet
NCT06712719 | NOT_YET_RECRUITING | NA
14 Participants

Effects of Dietary Phosphorus on Phosphorus and Calcium Whole-Body Balance and Kinetics in Moderate CKD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-02-01
Completion: 2027-05-28
Conditions
CKD
Interventions
OTHER
No Results Yet
NCT06702631 | RECRUITING | EARLY_PHASE1
60 Participants

Nitrous Oxide Neuroimaging

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-13
Completion: 2026-06-01
Conditions
Anesthesia Pain Amnesia
Interventions
DRUG DEVICE
No Results Yet
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