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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06729957 | RECRUITING | NA
360 Participants

Addressing Barriers to Care for Substance Use Disorder Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-16
Completion: 2026-08-21
Conditions
Drug Use Disorders Alcohol-Related Disorders Substance Use Disorder (SUD)
Interventions
BEHAVIORAL
No Results Yet
NCT06727812 | RECRUITING | PHASE1
206 Participants

Multicenter Phase I Study of HRS-6208 in Patients With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-17
Completion: 2027-08-31
Conditions
Solid Tumors
Interventions
DRUG
No Results Yet
NCT06724913 | ACTIVE_NOT_RECRUITING | NA
100 Participants

Efficacy and Tolerability of a Specialized Food Products for Dietary Therapeutic and Preventive Nutrition Based on Ice Cream (Ice Cream With Brazzein, Maltitol and Oligofructose; Ice Cream With Brazzein, Erythritol, Maltitol and Inulin) Compared to Standard (Sundae) Ice Cream

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-06-01
Completion: 2025-12-31
Conditions
Non-Alcoholic Steatohepatitis (NASH) Diabetes Mellitus Type 2 (T2DM)
Interventions
OTHER
No Results Yet
NCT06722378 | RECRUITING | NA
630 Participants

A Trial to Improve Family Clinical Note Access and Outcomes for Hospitalized Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-04-01
Completion: 2029-04-30
Conditions
Hospitalized Child Pediatric Patient Safety Medical Errors Parental Engagement in Care Inpatient Pediatric Care
Interventions
OTHER
No Results Yet
NCT06722235 | RECRUITING | PHASE3
171 Participants

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-02-27
Completion: 2027-12-28
Conditions
Immune Thrombocytopenic Purpura (ITP)
Interventions
DRUG
No Results Yet
NCT06720519 | COMPLETED
170 Participants

Molecular Panel Evaluation for Diagnosis of Infections of the Central Nervosous System

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2024-04-17
Completion: 2024-10-17
Conditions
Infections Nervous System
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06719921 | RECRUITING | NA
724 Participants

Catheter Ablation for Atrial Fibrillation in Non-Fluoroscopic Lab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-04-22
Completion: 2028-04-30
Conditions
Atrial Fibrillation (AF)
Interventions
PROCEDURE OTHER
No Results Yet
NCT06717867 | RECRUITING | PHASE2
200 Participants

Long-Term PEA Safety Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-22
Completion: 2027-06-30
Conditions
Safety Healthy
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT06715462 | WITHDRAWN | PHASE3
0 Participants

Efficacy and Safety of the N0750 Compared to Monotherapies in the Treatment of Painful Diabetic Peripheral Neuropathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-04-30
Completion: 2028-03-31
Conditions
Painful Diabetic Peripheral Neuropathy (PDPN)
Interventions
DRUG
No Results Yet
NCT06712719 | NOT_YET_RECRUITING | NA
14 Participants

Effects of Dietary Phosphorus on Phosphorus and Calcium Whole-Body Balance and Kinetics in Moderate CKD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-02-01
Completion: 2027-05-28
Conditions
CKD
Interventions
OTHER
No Results Yet
NCT06702631 | RECRUITING | EARLY_PHASE1
60 Participants

Nitrous Oxide Neuroimaging

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-13
Completion: 2026-06-01
Conditions
Anesthesia Pain Amnesia
Interventions
DRUG DEVICE
No Results Yet
NCT06696001 | RECRUITING | NA
45 Participants

Neuroscience of Psychotherapy for Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-04-11
Completion: 2026-06-01
Conditions
Depression
Interventions
BEHAVIORAL
No Results Yet
NCT06695845 | RECRUITING | PHASE2
200 Participants

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-14
Completion: 2026-12-31
Conditions
Breast Cancer Gastric Cancer Esophageal Cancer Gastroesophageal Cancer Colorectal Cancer Endometrial Cancer Non-small Cell Lung Cancer Ovarian Cancer Urothelial Carcinoma Salivary Gland Cancer Pancreatic Cancer HER-2 Protein Overexpression
Interventions
DRUG
No Results Yet
NCT06686576 | RECRUITING | PHASE3
363 Participants

A Study of Neoadjuvant QL1706 in Participants With Untreated dMMR/MSI-H Resectable Colon Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-12
Completion: 2030-12-31
Conditions
Colon Cancer
Interventions
DRUG
No Results Yet
NCT06684470 | RECRUITING | EARLY_PHASE1
20 Participants

Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a Neuromodulator

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-19
Completion: 2026-12-19
Conditions
IBS - Irritable Bowel Syndrome Diarrhea
Interventions
DRUG OTHER
No Results Yet
NCT06680050 | RECRUITING | PHASE2
21 Participants

Phase II Study of Radiotherapy Followed by Durvalumab and Ceralasertib in Stage III NSCLC Patients With Thoracic Relapses +/- Oligometastases After PACIFIC Regimen

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-08-07
Completion: 2028-06-30
Conditions
Non Small Cell Lung Cancer NSCLC
Interventions
DRUG RADIATION
No Results Yet
NCT06678789 | RECRUITING | NA
50 Participants

Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-02-14
Completion: 2026-08-01
Conditions
Cigarette Smoking Nicotine Dependence Smoking Cessation
Interventions
BEHAVIORAL
No Results Yet
NCT06677970 | RECRUITING | PHASE3
176 Participants

Outcome in Patients Treated With Endovascular Thrombectomy - optIMAL Blood Pressure Control 2 (OPTIMAL-BP 2)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-01
Completion: 2029-12-03
Conditions
Acute Ischemic Stroke
Interventions
DRUG
No Results Yet
NCT06677060 | RECRUITING | PHASE3
11300 Participants

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-03-14
Completion: 2029-12-17
Conditions
Heart Failure
Interventions
DRUG OTHER
No Results Yet
NCT06672549 | RECRUITING | PHASE3
125 Participants

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-11-18
Completion: 2027-02-28
Conditions
Obesity Overweight
Interventions
DRUG
No Results Yet
NCT06672484 | ACTIVE_NOT_RECRUITING
100 Participants

Walking Fatigability and Brain Activity in People With Multiple Sclerosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2024-05-22
Completion: 2025-09-13
Conditions
Multiple Sclerosis Healthy
No Results Yet
NCT06671925 | NOT_YET_RECRUITING | NA
80 Participants

A Community Health Worker-Led Program for Chronic Pain and Loneliness in Older Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-12-31
Completion: 2026-06-30
Conditions
Chronic Pain
Interventions
BEHAVIORAL
No Results Yet
NCT06659705 | RECRUITING | PHASE2
35 Participants

Cutting Edge Imaging With PET-FAPI for Earlier Pancreatic Cancer Diagnosis (INDIGO-FAPI)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-12-02
Completion: 2029-08-04
Conditions
Pancreatic Ductal Adenocarcinoma (PDAC)
Interventions
DRUG
No Results Yet
NCT06657157 | RECRUITING
80 Participants

Peripheral Neuropathy in Patients Receiving Enfortumab Vedotin and Pembrolizumab as First Line Treatment for Metastatic or Locally Advanced Urothelial Carcinoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-22
Completion: 2026-12-31
Conditions
Urothelial Cancer
No Results Yet
NCT06654466 | RECRUITING | NA
100 Participants

Closing the GAPS: Guideline Adherence, Prevention and Surveillance in Hereditary Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-12-01
Completion: 2027-03-31
Conditions
Hereditary Cancer Syndromes Clinical Decision Support
Interventions
DEVICE
No Results Yet
NCT06651463 | NOT_YET_RECRUITING | NA
50 Participants

Evaluation of the Feasibility of Camera Measurement of Colorimetric Parameters of the Brain During Neurosurgery Operations: Tissue Oximetry and Endogenous or Induced Fluorescence

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-01-01
Completion: 2028-01-01
Conditions
Brain Diseases
Interventions
OTHER
No Results Yet
NCT06651177 | RECRUITING | PHASE2
310 Participants

Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-12-12
Completion: 2027-06-30
Conditions
Opioid Use Disorder Opioid Use Disorder, Moderate Opioid Use Disorder, Severe
Interventions
DRUG OTHER
No Results Yet
NCT06641921 | COMPLETED | NA
330 Participants

Strategy TO Prevent Decompensated Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-05-01
Completion: 2025-10-01
Conditions
Heart Failure Remote Monitoring
Interventions
DEVICE
No Results Yet
NCT06638671 | RECRUITING | PHASE4
20 Participants

Short-Term Metformin Use in Young, Healthy Adults: Impacts on Exercise Capacity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-31
Completion: 2026-04-01
Conditions
Exercise Capacity Metformin
Interventions
DRUG
No Results Yet
NCT06636279 | COMPLETED | NA
80 Participants

A Randomized Study of Gas Bubble Technique in Cataract Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-10
Completion: 2025-02-10
Conditions
Corneal Endothelial Damage Following the Hard Nuclear Cataract Surgery
Interventions
PROCEDURE
No Results Yet
NCT06634420 | ACTIVE_NOT_RECRUITING | PHASE3
60 Participants

HAELO: A Phase 3 Study to Evaluate NTLA-2002 in Participants With Hereditary Angioedema (HAE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-01-15
Completion: 2026-04-30
Conditions
Hereditary Angioedema
Interventions
BIOLOGICAL
No Results Yet
NCT06632756 | COMPLETED | NA
16 Participants

Positive Psychology for Smoking Cessation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-10
Completion: 2025-09-30
Conditions
Mental Illness Tobacco Dependence
Interventions
BEHAVIORAL
No Results Yet
NCT06629090 | RECRUITING | PHASE2
36 Participants

Brain Blood Vessel Responses to Changes in Blood Flow: Younger Cohort

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-12-17
Completion: 2026-12-31
Conditions
Magnetic Resonance Imaging Cerebrovascular Circulation
Interventions
DEVICE DRUG
No Results Yet
NCT06626035 | NOT_YET_RECRUITING | PHASE3
500 Participants

Evaluation of Analgesia for Cardiac Elective Surgery in Children

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-01-31
Completion: 2029-01-31
Conditions
Pediatric Cardiac Surgery
Interventions
DRUG
No Results Yet
NCT06625671 | RECRUITING | PHASE1/PHASE2
148 Participants

A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-04
Completion: 2026-03-23
Conditions
Systemic Lupus Erythematosus (SLE)
Interventions
DRUG
No Results Yet
NCT06623019 | COMPLETED
413 Participants

Study of the Validity and Reliability of Two Digital Dynamometers in Older People

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-16
Completion: 2025-03-31
Conditions
Sarcopenia Old Age; Debility Frailty
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06616857 | RECRUITING | NA
30 Participants

Personalized Mobile Health Platform to Promote Physical Activity in Adolescents and Young Adults With Cystic Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2025-02-18
Completion: 2026-07-31
Conditions
Cystic Fibrosis (CF)
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06614946 | NOT_YET_RECRUITING | NA
120 Participants

Improving Coping to Reduce Suicide Risk Following ED Discharge

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-02-28
Completion: 2027-02-28
Conditions
Suicidal Suicide, Attempted Suicidal Ideation
Interventions
BEHAVIORAL
No Results Yet
NCT06609889 | RECRUITING | PHASE1/PHASE2
10 Participants

A Safety and Efficacy of Intrathecally Administered ION283 in Patients With Lafora Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-12-03
Completion: 2027-10-31
Conditions
Lafora Disease
Interventions
GENETIC
No Results Yet
NCT06604949 | ACTIVE_NOT_RECRUITING | PHASE1
12 Participants

A Study of Single Dose of LP-003 in Healthy Adult Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2024-10-23
Completion: 2026-11-30
Conditions
Chronic Spontaneous Urticaria
Interventions
DRUG
No Results Yet
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