Clinical Trials Updated in 2025

NCT06422884 | RECRUITING | PHASE2

200 Participants

A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-11-15

Completion: 2026-10-31

Conditions

Idiopathic Pulmonary Fibrosis Progressive Fibrosing Interstitial Lung Disease

Interventions

DRUG

No Results Yet

NCT06419439 | RECRUITING | PHASE2

44 Participants

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-12-03

Completion: 2028-12-01

Conditions

Chronic Low Back Pain Depression

Interventions

DRUG BEHAVIORAL

No Results Yet

NCT06415357 | ACTIVE_NOT_RECRUITING | NA

164 Participants

Zambia Healthy Choices Project for Emerging Adults Living With HIV

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-04-20

Completion: 2026-03-31

Conditions

Pre-Exposure Prophylaxis

Interventions

BEHAVIORAL

No Results Yet

NCT06412757 | RECRUITING | PHASE3

278 Participants

Silexan in the Treatment Of Posttraumatic Stress Disorder Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-08-26

Completion: 2027-05-31

Conditions

Post Traumatic Stress Disorder

Interventions

DRUG OTHER

No Results Yet

NCT06411691 | RECRUITING | PHASE1

54 Participants

KRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal Cancer and Pancreatic Ductal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-06-24

Completion: 2028-03-01

Conditions

Colorectal Cancer Pancreatic Cancer

Interventions

DRUG

No Results Yet

NCT06410807 | COMPLETED

23 Participants

Development of Web-Based Mind-Body Trainings for Adults With Subjective Concerns

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2024-11-01

Completion: 2025-05-02

Conditions

Aging Focus Groups

Interventions

OTHER

No Results Yet

NCT06407934 | ACTIVE_NOT_RECRUITING | PHASE3

1541 Participants

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-05-08

Completion: 2026-06-29

Conditions

Dermatitis Atopic

Interventions

DRUG

No Results Yet

NCT06404333 | COMPLETED | PHASE2

13 Participants

Evaluating Pediatric Ivermectin in Children Under 15 kg (EPIC-15)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-02-25

Completion: 2025-11-30

Conditions

Scabies

Interventions

DRUG

No Results Yet

NCT06403137 | COMPLETED | NA

51 Participants

Plant Protein Blend and Milk Protein Supplements in Older Individuals

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-06-26

Completion: 2025-12-05

Conditions

Sarcopenia Skeletal Muscle Atrophy Protein Malnutrition

Interventions

DIETARY_SUPPLEMENT BEHAVIORAL

No Results Yet

NCT06386172 | COMPLETED | NA

65 Participants

Electronic Decision-support System to Improve Detection and Care of Patients With Chronic Kidney Disease in Stockholm

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2023-09-09

Completion: 2025-09-30

Conditions

Chronic Kidney Diseases

Interventions

OTHER

No Results Yet

NCT06384170 | SUSPENDED

12 Participants

Closed Loop Spinal Cord Stimulation for Neuromodulation of Upper Motor Neuron Lesion Spasticity

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2024-12-03

Completion: 2026-01-31

Conditions

Chronic Pain Spasticity as Sequela of Stroke Upper Motor Neuron Lesion

Interventions

DEVICE

No Results Yet

NCT06372860 | COMPLETED | NA

43 Participants

DPP Feasibility Study of Breastfeeding - eMOMS 2.0

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-04-30

Completion: 2025-08-31

Conditions

Overweight or Obesity Pregnancy

Interventions

BEHAVIORAL

No Results Yet

NCT06369948 | COMPLETED | NA

60 Participants

Quality Of Recovery After Pericapsular Nerve Group (PENG) Block For Hip Hemiarthroplasty Under Spinal Anesthesia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-03-01

Completion: 2024-09-01

Conditions

Hip Hemiarthroplasty

Interventions

PROCEDURE DRUG

No Results Yet

NCT06366750 | ACTIVE_NOT_RECRUITING | PHASE2

140 Participants

A Study of Barzolvolimab in Patients With Prurigo Nodularis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-04-12

Completion: 2026-06-30

Conditions

Prurigo Nodularis

Interventions

BIOLOGICAL OTHER

No Results Yet

NCT06365853 | RECRUITING | PHASE2

100 Participants

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-07-29

Completion: 2026-06-30

Conditions

Recurrent Ovarian Cancer Folate Receptor-Alpha Positive

Interventions

DRUG

No Results Yet

NCT06364371 | RECRUITING

106 Participants

Dynamic Multi-omics Integration Model to Predict Neoadjuvant Therapy Response in Locally Advanced Rectal Cancer

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2024-06-01

Completion: 2027-06-01

Conditions

Predictive Cancer Model Pathologic Complete Response

Interventions

OTHER

No Results Yet

NCT06359379 | TERMINATED | PHASE2

30 Participants

Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-09-02

Completion: 2025-12-01

Conditions

Glioblastoma, IDH-wildtype

Interventions

DRUG

No Results Yet

NCT06355323 | COMPLETED | NA

46 Participants

Bronchiectasis Prevalence in Patients With Primary Humoral Immunodefiency in Champagne-Ardenne Region, France

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2022-11-28

Completion: 2024-03-11

Conditions

Primary Immunodeficiency Common Variable Immunodeficiency Igg Subclass Deficiency Selective IgM Deficiency

Interventions

OTHER

No Results Yet

NCT06351631 | RECRUITING | PHASE3

400 Participants

A Study to Evaluate Safety and Efficacy of Bomedemstat (MK-3543-017)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-05-23

Completion: 2034-12-04

Conditions

Thrombocythemia, Essential Primary Myelofibrosis Myelofibrosis Post-polycythemia Vera Myelofibrosis Post-essential Thrombocythemia Myelofibrosis Polycythemia Vera

Interventions

DRUG

No Results Yet

NCT06346873 | WITHDRAWN | NA

0 Participants

Demonstrating Efficacy of JOGO for the Treatment of Tremor

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2025-01-03

Completion: 2025-01-03

Conditions

Functional Neurological Disorder

Interventions

DEVICE

No Results Yet

NCT06344130 | RECRUITING | PHASE1

28 Participants

Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-10-01

Completion: 2027-12-31

Conditions

Astrocytoma Glioma Recurrent Glioblastoma

Interventions

RADIATION

No Results Yet

NCT06338553 | RECRUITING | EARLY_PHASE1

24 Participants

GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-06-12

Completion: 2027-03-31

Conditions

Type 1 Diabetes

Interventions

DRUG

No Results Yet

NCT06334107 | RECRUITING | NA

60 Participants

Mitochondrial DNA Signatures of Poor Aerobic Exercise Trainability in Young Adults Born Preterm

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-05-01

Completion: 2026-12-01

Conditions

Preterm Birth

Interventions

BEHAVIORAL

No Results Yet

NCT06309355 | COMPLETED | PHASE2

35 Participants

Topical YR001 Ointment in Adult With Mild to Moderate Atopic Dermatitis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-06-19

Completion: 2025-11-20

Conditions

Atopic Dermatitis

Interventions

DRUG OTHER

No Results Yet

NCT06307652 | RECRUITING | PHASE3

4800 Participants

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-04-12

Completion: 2027-06-11

Conditions

Heart Failure and Impaired Kidney Function

Interventions

DRUG

No Results Yet

NCT06297265 | RECRUITING | NA

50 Participants

Manual Lymphatic Drainage Breast Massage in Breast Cancer Patients After Breast Conserving Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-05-24

Completion: 2026-05-24

Conditions

Anatomic Stage 0 Breast Cancer AJCC v8 Anatomic Stage IA Breast Cancer AJCC v8 Localized Breast Carcinoma

Interventions

OTHER RADIATION

No Results Yet

NCT06296420 | RECRUITING

Study Type: OBSERVATIONAL

Last Updated: 2025-12-18

Start Date: 2022-03-09

Completion: 2036-10-04

Conditions

Leukocyte Adhesion Deficiency

No Results Yet

NCT06277479 | COMPLETED

Study Type: INTERVENTIONAL

Last Updated: 2025-12-18

Start Date: 2024-02-29

Completion: 2027-02-01

Conditions

Adolescent Behavior Adolescent - Emotional Problem Mental Health Issue Psychosocial Functioning Depression Anxiety

Interventions

BEHAVIORAL

No Results Yet