Clinical Trials
Showing trials with last updates posted in 2025.
84
Participants
Biomarker Effects of ALZ-801 in APOE4 Carriers With Early Alzheimer's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-09-30
Completion:
2023-06-20
Conditions
Early Alzheimer's Disease
Interventions
DRUG
No Results Yet
596
Participants
A Long-Term Safety and Tolerability Extension Study Evaluating Atogepant for the Prevention of Chronic or Episodic Migraine
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-02-19
Completion:
2025-10-20
Conditions
Episodic Migraine
Chronic Migraine
Interventions
DRUG
No Results Yet
72
Participants
To Assess the Safety and Tolerability of Tafasitamab Alone or in Combination With Other Drugs in Japanese Participants With Non-Hodgkins Lymphoma (NHL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-12-15
Completion:
2026-12-31
Conditions
Non Hodgkins Lymphoma
Diffuse Large B-cell Lymphoma
Interventions
DRUG
No Results Yet
31
Participants
Feasibility and Efficacy of Perioperative Nivolumab With or Without Relatlimab for Patients With Potentially Resectable Hepatocellular Carcinoma (HCC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-05-28
Completion:
2025-09-02
Conditions
Hepatocellular Carcinoma
Interventions
DRUG
No Results Yet
73
Participants
Controlling Faecal Incontinence With a Novel Anal Device: a Cost-effectiveness Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-06-06
Completion:
2024-08-01
Conditions
Faecal Incontinence
Interventions
DEVICE
OTHER
No Results Yet
250
Participants
Epidemiology of Young Lung Cancer - Survey
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2021-02-01
Completion:
2025-12-10
Conditions
NSCLC
Interventions
OTHER
No Results Yet
4
Participants
Cabozantinib in Patients With Metastatic Castrate Resistant Prostate Cancer (mCRPC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-03-03
Completion:
2025-05-12
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
48
Participants
Validation of Continuous Monitoring of Vital Signs in Children With a Connected Patch
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2025-02-02
Completion:
2026-10-01
Conditions
Vital Signs
Interventions
DEVICE
No Results Yet
52
Participants
Biliary Anastomosis Using Surgical Loupe Versus Microscope in Living Donor Liver Transplantation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-12-02
Completion:
2023-03-30
Conditions
Liver Failure
Liver Diseases
Liver Cancer
Liver Neoplasms
Liver Dysfunction
Interventions
OTHER
No Results Yet
155
Participants
Phase 1b Study of Dato-DXd in Combination With Immunotherapy With or Without Carboplatin in Advanced or Metastatic Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-02-02
Completion:
2026-04-30
Conditions
Advanced or Metastatic NSCLC
Interventions
DRUG
No Results Yet
866
Participants
Registry Study of Pregnancy and Breast Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2019-11-18
Completion:
2030-01-31
Conditions
Breast Cancer and Pregnancy
No Results Yet
750
Participants
Poly-omic Predictors of Symptom Duration and Recovery for Adolescent Concussion
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2021-01-18
Completion:
2025-11-01
Conditions
Concussion, Mild
No Results Yet
40
Participants
A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-05-20
Completion:
2027-10-31
Conditions
Solid Tumors
Lymphoma
Interventions
DRUG
No Results Yet
14
Participants
Evaluation of the Predictive Value of 18F-fluorodeoxyglucose Positron Emission Tomography and Brain Perfusion Computed Tomography for the Efficacy of Anti-angiogenic Therapy (Bevacizumab) in Recurrent Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-12-16
Completion:
2023-06-27
Conditions
Glioblastoma
Interventions
OTHER
No Results Yet
60
Participants
Hybrid Robot+FES Stroke Rehabilitation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-08-01
Completion:
2026-10-01
Conditions
Stroke
Interventions
COMBINATION_PRODUCT
No Results Yet
2701
Participants
Clinical Evaluation of Adults Undergoing Elective Surgery Utilizing Intraoperative Incisional Wound Irrigation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2023-08-02
Completion:
2025-09-30
Conditions
Surgical Site Infection
Interventions
PROCEDURE
No Results Yet
918
Participants
Efficacy of a Smoke-Free Homes Intervention
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-11-11
Completion:
2025-07-27
Conditions
Cessation, Smoking
Interventions
BEHAVIORAL
No Results Yet
50
Participants
Telehealth Visits to Discuss Advanced Directives for Patients Newly Diagnosed With High Grade Glioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-10-08
Completion:
2026-07-31
Conditions
Glioma
Interventions
BEHAVIORAL
No Results Yet
102
Participants
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-10-26
Completion:
2026-07-31
Conditions
Central Nervous System Neoplasms
Glioblastoma
Gliosarcoma, Adult
Anaplastic Oligodendroglioma
Anaplastic Astrocytoma
Pilocytic Astrocytoma
Oligodendroglioma
Gliomatosis Cerebri
Pleomorphic Xanthoastrocytoma
Anaplastic Pleomorphic Xanthoastrocytoma
Diffuse Midline Glioma, H3 K27M-Mutant
Ependymoma
Ependymoma, Anaplastic
Medulloblastoma
Teratoid Rhabdoid Tumor
Neuroectodermal Tumors, Primitive
Neuroectodermal Tumors
Anaplastic Meningioma
Atypical Meningioma
Choroid Plexus Neoplasms
Pineal Tumor
Diffuse Astrocytoma
Glial Tumor
Interventions
DRUG
No Results Yet
68
Participants
Nightmare Rescripting and Rehearsal
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-01-21
Completion:
2025-12-09
Conditions
Nightmare
Sleep
Interventions
BEHAVIORAL
No Results Yet
505
Participants
Depression Screening in Black Churches
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-08-01
Completion:
2025-04-12
Conditions
Depression
Interventions
BEHAVIORAL
No Results Yet
100
Participants
Examination of the Impact of CalmiGo's Stress Management Device on Vascular Heath and Cardiovascular Disease Risk.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-01-13
Completion:
2026-12-31
Conditions
Myocardial Infarction
Interventions
DEVICE
No Results Yet
284
Participants
A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIa AL Amyloidosis (CARES)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-11-03
Completion:
2025-04-08
Conditions
AL Amyloidosis
Interventions
DRUG
OTHER
No Results Yet
23
Participants
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-05-18
Completion:
2025-01-14
Conditions
Sjogren's Syndrome
Interventions
DRUG
OTHER
Compassionate Use Program to Access Trametinib and Dabrafenib for Patients With BRAF Mutation-positive Metastatic Melanoma
Study Type:
EXPANDED_ACCESS
Last Updated:
2025-12-18
Conditions
Melanoma
Interventions
DRUG
No Results Yet
8
Participants
Adjuvant Hypofractionated Whole Pelvis Radiation Therapy in Endometrial Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-02-04
Completion:
2025-01-30
Conditions
Endometrial Cancer
Interventions
RADIATION
No Results Yet
575
Participants
Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPC
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-10-19
Completion:
2024-04-19
Conditions
Metastatic Prostate Cancer
Prostate Adenocarcinoma
Interventions
DRUG
105
Participants
Study to Understand Risk and Resilience Opportunity for Newborns After Delivery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-01-26
Completion:
2026-03-01
Conditions
A. Longitudinal Cohort n=400
B. Lower Risk (n=45) and Higher Risk (n=105) Randomized 2:1 to PERCCS Intervention
Interventions
BEHAVIORAL
No Results Yet
880
Participants
ADAPT for Adolescents Adolescents
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-04-06
Completion:
2025-09-13
Conditions
HIV/AIDS
Interventions
BEHAVIORAL
No Results Yet
28
Participants
Study of Dietary Composition in Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-10-05
Completion:
2025-03-31
Conditions
Inflammatory Bowel Diseases
Crohn Disease
Interventions
OTHER
No Results Yet
1125
Participants
Effects of Systematic Cervical Exam Training on Labor and Delivery Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-07-23
Completion:
2026-06-30
Conditions
Delivery Problem
Cervix; Pregnancy
Pregnancy Related
Interventions
BEHAVIORAL
No Results Yet
168
Participants
Myo-Inositol for Infertility in PCOS
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-02-07
Completion:
2026-02-28
Conditions
Polycystic Ovary Syndrome
Interventions
DIETARY_SUPPLEMENT
No Results Yet
238
Participants
Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-08-20
Completion:
2026-12-31
Conditions
Diffuse Large B-cell Lymphoma
Interventions
DRUG
OTHER
No Results Yet
268
Participants
Robotic Versus Open Pancreaticoduodenectomy for Pancreatic and Periampullary Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-09-28
Completion:
2024-11-28
Conditions
Pancreatic Adenocarcinoma
Pancreatic Cysts
Pancreatic Endocrine Tumors
Chronic Pancreatitis
Cholangiocarcinoma, Extrahepatic
Ampullary Adenocarcinoma
Duodenal Adenocarcinoma
Interventions
PROCEDURE
No Results Yet
159
Participants
Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-09-01
Completion:
2023-01-13
Conditions
Gliosarcoma
MGMT-Unmethylated Glioblastoma
Interventions
PROCEDURE
BIOLOGICAL
DEVICE
OTHER
RADIATION
DRUG
1000
Participants
RASopathy Biorepository
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2017-06-27
Completion:
2065-12-31
Conditions
RAS Mutation
Neurofibromatosis 1
Noonan Syndrome
Noonan Syndrome With Multiple Lentigines
Noonan Neurofibromatosis Syndrome
Cardiofaciocutaneous Syndrome
Costello Syndrome
Legius Syndrome
Smith-Kingsmore Syndrome
MTOR Gene Mutation
GATOR-1 Gene Mutation
SYNGAP1-Related Intellectual Disability
DLG4
MAPK1 Gene Mutation
No Results Yet
120
Participants
Stroke Prevention in the Wisconsin Native American Population
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-04-14
Completion:
2025-10-01
Conditions
Stroke
Atherosclerosis
Interventions
OTHER
No Results Yet
18500
Participants
Health Information Technology to Reduce Disparities in Adolescent Health Outcomes: A Pragmatic Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2023-03-08
Completion:
2026-12-31
Conditions
Sexually Transmitted Diseases
Interventions
BEHAVIORAL
No Results Yet
24
Participants
Testing the Addition of Copanlisib to Eribulin in Metastatic Triple Negative Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-03-01
Completion:
2024-03-28
Conditions
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Triple-Negative Breast Carcinoma
Unresectable Triple-Negative Breast Carcinoma
Interventions
DRUG
PROCEDURE
240
Participants
Ivermectin Safety in Small Children
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2023-11-18
Completion:
2025-04-04
Conditions
Scabies
Interventions
DRUG
OTHER
No Results Yet
Showing 40 trials per page