Clinical Trials
Showing trials with last updates posted in 2025.
80
Participants
Triggering Motor Memory Consolidation in PD: Complex Practice of Fine Motor Tasks and Brain Activity During Learning
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-05-03
Completion:
2023-05-16
Conditions
Parkinson Disease
Interventions
BEHAVIORAL
No Results Yet
292
Participants
First-in-Human Study of ICT01 in Patients With Advanced Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-03-05
Completion:
2026-10-31
Conditions
Solid Tumor, Adult
Hematopoietic/Lymphoid Cancer
Interventions
BIOLOGICAL
No Results Yet
32
Participants
Genotypic Influences on Network Progression in Parkinson's Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2020-02-24
Completion:
2025-12-31
Conditions
Parkinson's Disease
Interventions
GENETIC
RADIATION
OTHER
No Results Yet
90
Participants
Study of Stem Cell Transplant vs. Non-Transplant Therapies in High-Risk Myelofibrosis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2020-08-05
Completion:
2026-12-31
Conditions
Myelofibrosis
High-Risk Cancer
Bone Marrow Cancer
Interventions
BIOLOGICAL
DRUG
No Results Yet
200
Participants
Clinical Trial to Evaluate Papilocare® Gel Efficacy Into Repairment of Cervical Lesions Caused by HPV
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2018-08-07
Completion:
2022-11-30
Conditions
HPV Infection
Lesion Cervix
Interventions
DEVICE
No Results Yet
180
Participants
Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-01-22
Completion:
2023-05-08
Conditions
Premature Lungs
Respiratory Distress Syndrome
Surfactant Deficiency Syndrome Neonatal
Interventions
PROCEDURE
No Results Yet
296
Participants
Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-12-10
Completion:
2026-10-30
Conditions
Solid Tumor
Non-Small Cell Lung Cancer
Head and Neck Cancer
Melanoma
Gastric Cancer
Renal Cell Carcinoma
Urothelial Carcinoma
Interventions
DRUG
No Results Yet
55
Participants
WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-12-20
Completion:
2022-10-30
Conditions
Anaplastic Astrocytoma, IDH-Wildtype
Glioblastoma, IDH-Wildtype
Metastatic Lung Non-Small Cell Carcinoma
Metastatic Malignant Neoplasm in the Central Nervous System
Stage IV Lung Cancer AJCC v8
Interventions
PROCEDURE
DRUG
No Results Yet
100
Participants
Prostate Specific Membrane Antigen (PSMA) or (FACBC) PET/CT Site-Directed Therapy for Treatment of Prostate Cancer, Flu-BLAST-PC Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-09-30
Completion:
2028-07-01
Conditions
Prostate Adenocarcinoma
Interventions
PROCEDURE
RADIATION
DRUG
No Results Yet
308
Participants
Use of a Patient-Centered Electronic App to Increase ED Patient's Knowledge on HCV to Improve the HCV Care Continuum
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-03-24
Completion:
2026-07-31
Conditions
Hepatitis C
Interventions
OTHER
No Results Yet
110
Participants
Von Willebrand Factor in Pregnancy (VIP) Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2019-10-12
Completion:
2026-12-31
Conditions
Von Willebrand Diseases
Interventions
OTHER
DRUG
No Results Yet
170
Participants
Dose Escalation Study of a PD1-LAG3 Bispecific Antibody in Patients With Advanced and/or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-11-11
Completion:
2026-06-30
Conditions
Solid Tumors
Metastatic Melanoma
Non-small Cell Lung Cancer
Esophageal Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
200
Participants
Study Assessing MTD, Safety, Tolerability, PK and Anti-tumor Effects of LNS8801alone and With Pembrolizumab
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-10-21
Completion:
2026-12-31
Conditions
Solid Tumor, Adult
Interventions
DRUG
BIOLOGICAL
No Results Yet
82
Participants
Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-06-02
Completion:
2026-06-01
Conditions
Alcohol; Use, Problem
Posttraumatic Stress Disorder
Interventions
BEHAVIORAL
No Results Yet
76
Participants
Evaluation of ATRA Activity in Combination With Anastrozole in Pre-operative Phase of Operable Early Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-06-18
Completion:
2025-01-30
Conditions
Breast Neoplasm Female
Interventions
DRUG
No Results Yet
1686
Participants
SyncAV Post-Market Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-10-03
Completion:
2026-05-31
Conditions
Congestive Heart Failure
Interventions
DEVICE
No Results Yet
40
Participants
Total Body Irradiation and Astatine-211-Labeled BC8-B10 Monoclonal Antibody for the Treatment of Nonmalignant Diseases
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-06-16
Completion:
2028-01-09
Conditions
Non-Malignant Neoplasm
Interventions
BIOLOGICAL
DRUG
RADIATION
PROCEDURE
No Results Yet
231
Participants
A Study of REGN5093 in Adult Patients With Mesenchymal Epithelial Transition Factor (MET)-Altered Advanced Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-01-07
Completion:
2032-04-22
Conditions
NSCLC
Interventions
DRUG
No Results Yet
1655
Participants
ObseRvation After Acute Coronary Syndrome for deveLopment of trEatment Options
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2014-11-05
Completion:
2018-02-20
Conditions
Acute Coronary Syndrome
No Results Yet
250
Participants
Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-08-09
Completion:
2027-03-31
Conditions
Haematological Malignancy
Acute Myeloid Leukemia
Non Hodgkin Lymphoma
Multiple Myeloma
Higher-risk Myelodysplastic Syndrome
Peripheral T Cell Lymphoma
Interventions
DRUG
No Results Yet
70
Participants
An Observational LTFU Study for Patients Previously Treated With Autologous ex Vivo Gene Therapy for ADA-SCID
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2019-09-26
Completion:
2040-08-31
Conditions
Adenosine Deaminase Deficiency
Severe Combined Immunodeficiency (SCID)
Interventions
BIOLOGICAL
No Results Yet
204
Participants
rTMS in Alleviating Pain and Co-Morbid Symptoms in Gulf War Veterans Illness (GWVI)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-10-01
Completion:
2025-06-30
Conditions
Gulf War Illness
Depression
Interventions
DEVICE
No Results Yet
320
Participants
Crystalloid Fluid Choice and Neurological Outcome in Patients After Subarachnoid Haemorrhage
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2022-05-24
Completion:
2025-12-31
Conditions
Subarachnoid Hemorrhage
Critical Illness
Infusion Fluid
Sodium Disorder
Interventions
DRUG
No Results Yet
133
Participants
Paracetamol Versus Ibuprofen in Premature Infants With Hemodynamically Significant Patent Ductus Arteriosus
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2017-07-07
Completion:
2024-12-18
Conditions
Patent Ductus Arteriosus After Premature Birth
Interventions
DRUG
No Results Yet
79
Participants
Study of Lenalidomide/Ixazomib/Dexamethasone/Daratumumab in Transplant-Ineligible Patients With Newly Diagnosed MM
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-10-21
Completion:
2026-12-31
Conditions
Myeloma, Multiple
Interventions
DRUG
No Results Yet
138
Participants
Impact of Patient Reported Outcomes for Pre-chemotherapy Medical Decision in Day Patients With Digestive Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-11-16
Completion:
2021-11-11
Conditions
Digestive Cancer
Interventions
OTHER
No Results Yet
261
Participants
Envarsus XR Compared to Immediate Release Tacrolimus
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-07-18
Completion:
2022-03-29
Conditions
Kidney Transplant Recipients
Interventions
DRUG
175
Participants
Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-12-04
Completion:
2027-11-19
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
6
Participants
A Feasibility Study on the Safety and Preliminary Efficacy of Bilateral Subthalamotomy Using MRgFUS for Treatment of PD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-06-18
Completion:
2023-11-07
Conditions
Parkinson Disease
Neurologic Manifestations
Interventions
DEVICE
No Results Yet
20
Participants
Ultrasound for the Detection of Oxaliplatin-Induced Peripheral Neuropathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-12-17
Completion:
2025-11-26
Conditions
Gastrointestinal Cancer
Colorectal Cancer
Interventions
DIAGNOSTIC_TEST
PROCEDURE
OTHER
No Results Yet
896
Participants
An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-09-05
Completion:
2029-06-19
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
80
Participants
Evaluating Different Low-level Laser Therapies to Treat Neck Pain in Air Force Pilots and Flight Crew
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-10-01
Completion:
2025-12-09
Conditions
Neck Pain
Interventions
PROCEDURE
No Results Yet
69
Participants
Is Periacetabular Osteotomy Superior to Progressive Resistance Training?
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-07-01
Completion:
2025-09-15
Conditions
Hip Dysplasia
Interventions
PROCEDURE
OTHER
No Results Yet
1700
Participants
Cycled Phototherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2020-07-16
Completion:
2025-11-04
Conditions
Hyper Bilirubinemia
Premature Infant
Interventions
DEVICE
No Results Yet
600
Participants
Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2018-09-15
Completion:
2026-12-30
Conditions
Opioid-use Disorder
Opioid Use, Unspecified
Buprenorphine Dependence
Interventions
DIAGNOSTIC_TEST
DRUG
No Results Yet
18
Participants
ASTX727 in Recurrent/Progressive Non-enhancing IDH Mutant Gliomas
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-07-12
Completion:
2027-01-01
Conditions
Neurological Cancer
Interventions
DRUG
No Results Yet
477
Participants
Prophylactic Reinforcement of Ventral Abdominal Incisions Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-12-12
Completion:
2029-12-31
Conditions
Open Midline Laparotomy
Interventions
DEVICE
No Results Yet
145
Participants
Robotic-Assisted da Vinci System Prophylactic Nipple-Sparing Mastectomy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2021-03-26
Completion:
2027-04-30
Conditions
Nipple Sparing Mastectomy
Interventions
DEVICE
No Results Yet
2000
Participants
The Johns Hopkins Heartburn Center Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-18
Start Date:
2019-04-27
Completion:
2026-12-31
Conditions
Gastroesophageal Reflux Disease
Barrett Esophagus
Laryngopharyngeal Reflux
Esophagitis
No Results Yet
160
Participants
Sex Differences in the Response to Abstinence From Alcohol.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-18
Start Date:
2019-04-10
Completion:
2026-08-31
Conditions
Alcohol Use Disorder
Interventions
BEHAVIORAL
DRUG
No Results Yet
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