Clinical Trials
Showing trials with last updates posted in 2025.
10
Participants
Shareholder-driven Co-design and Piloting of Spanish Educational Videos About High Yield Pediatric Oncology Topics
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-31
Completion:
2026-12-31
Conditions
Pediatric Cancer
Interventions
OTHER
No Results Yet
20
Participants
Hearing Loss and Genetic Risks for Alzheimer's Disease and Related Dementia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2027-07-01
Completion:
2030-06-30
Conditions
Hearing Loss, Adult-Onset
Dementia
Interventions
DEVICE
No Results Yet
5
Participants
Deep Brain Stimulation for Spinocerebellar Ataxia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-03-31
Completion:
2029-03-31
Conditions
Spinocerebellar Ataxia (SCA)
Spinocerebellar Ataxia Type 6
Interventions
DEVICE
No Results Yet
17
Participants
Opioid-Free Pain Management After NUSS Surgery in Adolescents
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2025-06-01
Completion:
2025-09-30
Conditions
Nerve Block
Interventions
PROCEDURE
No Results Yet
10
Participants
Effects of Vagus Nerve Stimulation on Temporomandibular Disorders.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-02-01
Completion:
2026-12-31
Conditions
TMD
Temporomandibular Disorders (TMDs)
Interventions
DEVICE
No Results Yet
540
Participants
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-31
Completion:
2028-06-30
Conditions
Pulmonary Hypertension Associated With HFpEF
Interventions
DRUG
No Results Yet
120
Participants
Evaluation of NBI-1117570 in Inpatient Adults With Schizophrenia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-31
Completion:
2027-08-31
Conditions
Schizophrenia
Interventions
DRUG
No Results Yet
150
Participants
An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-31
Completion:
2028-02-29
Conditions
Bipolar I Disorder
Mania
Interventions
DRUG
No Results Yet
42
Participants
Surgical Evacuation Versus Methotrexate Injection in Treatment of Caesarean Scar Pregnancy [Clinical Trial ]
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-20
Completion:
2027-01-20
Conditions
Caesarean Scar Pregnancy
Interventions
PROCEDURE
No Results Yet
214
Participants
PRImary Care Strategies for Weight Management (PRISM) Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-03-01
Completion:
2028-04-01
Conditions
Obesity
Interventions
BEHAVIORAL
No Results Yet
[Trial of device that is not approved or cleared by the U.S. FDA]
Last Updated:
2025-12-17
No Results Yet
375
Participants
Single-lumen Endotracheal Intubation in ENB-guided Localization and Resection of Pulmonary Nodules
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2023-08-01
Completion:
2024-12-12
Conditions
Lung Nodule
Interventions
PROCEDURE
No Results Yet
200
Participants
The Benefits of Wearable AI in Post-Discharge Management of AMI Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-30
Completion:
2026-06-30
Conditions
Acute Myocardial Infarction
Heart Failure
Interventions
COMBINATION_PRODUCT
No Results Yet
80
Participants
Transition to KPL-387 Monotherapy Dosing & Administration Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-31
Completion:
2027-12-31
Conditions
Recurrent Pericarditis
Heart Diseases
Pericarditis
Interventions
DRUG
No Results Yet
300
Participants
Phase 2b, Open Label, Multisite, Randomized Crossover Study of DPP Versus 2PR
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-03-15
Completion:
2028-03-15
Conditions
Pregnancy
HIV Infections
Interventions
DRUG
No Results Yet
200
Participants
MDMA-Assisted Massed Exposure Therapy for PTSD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-31
Completion:
2030-01-31
Conditions
Post Traumatic Stress Disorder
Interventions
DRUG
BEHAVIORAL
No Results Yet
35
Participants
DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-31
Completion:
2031-01-31
Conditions
Refractory Melanoma
Interventions
BIOLOGICAL
PROCEDURE
DRUG
No Results Yet
200
Participants
Reliability and Effectiveness of New Enova Preloaded Intaocular Lens and Cartridge System
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-06-10
Completion:
2026-01-15
Conditions
Cataract Surgery
Intraocular Lens
Interventions
DEVICE
No Results Yet
14
Participants
TIL Therapy in cSCC and MCC
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-31
Completion:
2028-09-29
Conditions
Cutaneous Squamous Cell Carcinoma
Merkel Cell Carcinoma
Metastatic Cutaneous Squamous Cell Carcinoma
Skin Cancer
Interventions
BIOLOGICAL
DRUG
No Results Yet
72
Participants
Virtual Reality as a Method for Pain and Anxiety Control During First Trimester Procedural Abortion
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-02-28
Completion:
2026-08-31
Conditions
Abortion, First Trimester
Pain Management
Pain After Surgery
Satisfaction
Satisfaction With Care
Anxiety After Surgery
Interventions
DEVICE
OTHER
No Results Yet
535
Participants
Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-09-21
Completion:
2028-09-22
Conditions
Lung Non-Small Cell Carcinoma
Stage IIIB Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
Interventions
DRUG
BIOLOGICAL
PROCEDURE
OTHER
BEHAVIORAL
No Results Yet
200
Participants
Topical Anesthesia During Catheter Insertion for Cervical Ripening (TOLERANCE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2024-02-05
Completion:
2026-02-28
Conditions
Labor, Induced
Interventions
DRUG
OTHER
No Results Yet
428
Participants
A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-15
Completion:
2029-06-30
Conditions
Locally Advanced or Metastatic Malignant Solid Tumors
Interventions
DRUG
No Results Yet
60
Participants
A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-19
Completion:
2029-05-28
Conditions
Spinal Muscular Atrophy (SMA)
Interventions
BIOLOGICAL
OTHER
No Results Yet
60
Participants
The Safety of Reusing Walking Boot Components for Patients Recovering From Acute Foot and Ankle Injuries
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2024-09-25
Completion:
2026-09-30
Conditions
Foot Injuries
Ankle Injuries
Interventions
DEVICE
No Results Yet
16
Participants
The Use of Adjunct Oxygen High-Level Laser Therapy on the Clinical and Microbiological Outcomes of Peri-implant Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2024-02-05
Completion:
2025-07-07
Conditions
Peri-Implantitis and Peri-implant Mucositis
Interventions
COMBINATION_PRODUCT
DEVICE
No Results Yet
13
Participants
A Study of YTS109 Cell in Subjects With Relapsed/Refractory Autoimmune Hemolytic Anemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-25
Completion:
2026-12-25
Conditions
Autoimmune Hemolytic Anemia
Interventions
DRUG
No Results Yet
1000
Participants
Prediction of Targeted Therapy Efficacy in EGFR-mutant Lung Cancer Patients Using AI-based Multimodal Data
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-25
Completion:
2027-07-31
Conditions
Lung Cancer (NSCLC)
EGFR Activating Mutation
Adenocarcinoma Lung
Postoperative Adjuvant Therapy
Interventions
DIAGNOSTIC_TEST
No Results Yet
825
Participants
Lost in the Labyrinth: Predicting Central Neurological Causes of Vertigo Dizziness and Unsteadiness in the Emergency Department. A Multicentre Cross-sectional Observational Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2024-01-26
Completion:
2027-02-26
Conditions
ED With Vertigo
Dizziness
Unsteadiness
Interventions
DIAGNOSTIC_TEST
No Results Yet
400
Participants
Study Title: Oncological and Functional Results After Total Laryngectomy and Pharyngolaryngectomy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2025-03-14
Completion:
2030-12-31
Conditions
Laryngeal and Hypopharyngeal Tumors
Interventions
PROCEDURE
No Results Yet
50
Participants
A Pilot Study to Examine the Effect of Egb761 on Plasma Biomarker Levels and on Cognitive Function in Patients With MCI
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2024-08-20
Completion:
2026-12-31
Conditions
Alzheimer Disease (AD)
Mild Cognitive Impairment (MCI)
Interventions
DIETARY_SUPPLEMENT
No Results Yet
45
Participants
Using a Steroid Mouthwash to Prevent Mouth Sores During Chemotherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-31
Completion:
2027-07-31
Conditions
Oral Mucositis Due to Chemotherapy
Interventions
DRUG
No Results Yet
40
Participants
Extracorporeal Therapy and Therapeutic Drug Monitoring
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-12
Completion:
2027-01-31
Conditions
ICU Patients With ECMO And-or RRT and With Gram Negative Infections Susceptible to BL-BLIs
No Results Yet
50
Participants
TRT as an Adjunctive ERAS Therapy in ESRD Patients Undergoing Kidney Transplantation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-07-01
Completion:
2026-06-30
Conditions
Hypogonadism, Male
End Stage Renal Disease (ESRD)
Kidney Transplant
Interventions
DRUG
No Results Yet
32
Participants
Comparative Study of Per-oral Endoscopic Myotomy (POEM) in Treatment - naïve Achalasia Patients Versus Patients With Previous Pneumatic Dilation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-15
Completion:
2027-04-15
Conditions
Achalasia, Esophageal
Interventions
PROCEDURE
No Results Yet
50
Participants
Evaluating a Deep Neural Noise-Reduction Algorithm for Hearing Aids
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-10-16
Completion:
2026-04-30
Conditions
Hearing Loss, Cochlear
Interventions
DEVICE
OTHER
No Results Yet
60
Participants
Comparison of Erector Spinae Plane Block and Serratus Posterior Superior Intercostal Plane Block in Postoperative Pain Management After Coronary Artery Bypass Grafting
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2025-11-01
Completion:
2026-03-01
Conditions
Postoperative Pain After Thoracic Surgery
Coronary Artery Bypass Graft (CABG)
No Results Yet
40
Participants
Pharmacokinetics, Safety, and Tolerability of GOPRELTO and NUMBRINO in Pediatric Nasal Procedures
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-06
Completion:
2026-06-30
Conditions
Nasal Procedures
Nasal Anesthesia
Nasal Mucosa Surgery
Interventions
DRUG
No Results Yet
22
Participants
Soft Tissue Response and IL-1β Levels Around CAD/CAM-Milled vs 3D-Printed PMMA Healing Abutments
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-11-23
Completion:
2025-12-23
Conditions
Peri-implant Soft Tissue Healing
Interventions
DEVICE
No Results Yet
60
Participants
Evaluation Of Laser Versus Conventional Pulpotomies In Mature Molar Teeth With Irreversible Pulpitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-11-07
Completion:
2026-05-31
Conditions
Irreversible Pulpitis (Toothache)
Interventions
DEVICE
OTHER
No Results Yet
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