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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06699953 | ENROLLING_BY_INVITATION
20 Participants

Characterizing the EEG Signature of Fentanyl and Its Association With Drug Liking

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2025-02-04
Completion: 2026-06-30
Conditions
Brain Activity Related to Opioid Administration Brain Activity Related to Drug Liking
Interventions
OTHER
No Results Yet
NCT06697184 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
56 Participants

A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-01-23
Completion: 2027-06-30
Conditions
Chronic Lymphocytic Leukemia CLL
Interventions
DRUG
No Results Yet
NCT06695637 | WITHDRAWN | EARLY_PHASE1
0 Participants

Individualized Neuromodulation of Craving Control for Meth Use Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-01
Completion: 2029-09-01
Conditions
Substance Use Disorders Methamphetamine Use Disorders
Interventions
RADIATION
No Results Yet
NCT06694805 | RECRUITING | PHASE3
332 Participants

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-12-02
Completion: 2026-12-17
Conditions
HIV Infections
Interventions
DRUG
No Results Yet
NCT06686615 | RECRUITING
2000 Participants

A Study of Bempedoic Acid in Combination With Ezetimibe and Either Rosuvastatin or Atorvastatin in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2025-02-12
Completion: 2027-07-31
Conditions
Primary Hypercholesterolemiia Mixed Dyslipidemia
Interventions
DRUG
No Results Yet
NCT06682572 | ACTIVE_NOT_RECRUITING | PHASE2
16 Participants

A Study of Avutometinib + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer in Japanese Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-10-30
Completion: 2025-12-31
Conditions
Low Grade Serous Ovarian Cancer Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT06682403 | COMPLETED | NA
49 Participants

Distribution and Randomization of Gun Safety Devices to Measure Uptake and Preferences

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-06-01
Completion: 2024-10-01
Conditions
Gun Violence Prevention
Interventions
BEHAVIORAL
Results Available
NCT06682013 | RECRUITING | NA
36 Participants

Virtual Agent Feasibility in Oncology Patients (NTT Data)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-31
Completion: 2026-02-28
Conditions
Lung Cancer
Interventions
DEVICE OTHER
No Results Yet
NCT06678620 | ACTIVE_NOT_RECRUITING | PHASE2
992 Participants

Phase II Clinical Trial of 24-valent Pneumococcal Polysaccharide Conjugate Vaccine

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-04-20
Completion: 2025-04-21
Conditions
Pneumococcal Infectious Disease
Interventions
BIOLOGICAL
No Results Yet
NCT06676033 | RECRUITING | PHASE1
30 Participants

Epcoritamab in Chronic Lymphocytic Leukemia and Richter Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-07-18
Completion: 2027-07-01
Conditions
Leukemia, Chronic Lymphocytic Richter Syndrome
Interventions
DRUG
No Results Yet
NCT06672978 | RECRUITING | PHASE2
66 Participants

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Meropenem-Vaborbactam in Children With Complicated Urinary Tract Infection, Including Acute Pyelonephritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-06-03
Completion: 2027-01-31
Conditions
Acute Pyelonephritis Complicated Urinary Tract Infection
Interventions
DRUG
No Results Yet
NCT06672510 | RECRUITING | NA
118 Participants

Safety and Effectiveness of the Akura Thrombectomy System for Use in the Removal of Emboli From the Pulmonary Arteries in Treating Acute Pulmonary Embolism (PE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-01-01
Completion: 2026-12-31
Conditions
Pulmonary Embolism Acute
Interventions
DEVICE
No Results Yet
NCT06664619 | RECRUITING | PHASE3
724 Participants

A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-12-12
Completion: 2026-05-31
Conditions
Asthma
Interventions
DRUG
No Results Yet
NCT06660225 | NOT_YET_RECRUITING | NA
10 Participants

Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-02-28
Completion: 2029-09-30
Conditions
Obsessive-Compulsive Disorder
Interventions
DEVICE
No Results Yet
NCT06648759 | RECRUITING | NA
60 Participants

Vagal Stimulator to Reduce Nasogastric Tube Use

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-12-04
Completion: 2026-09-30
Conditions
Nasogastric Tube Intubation
Interventions
DEVICE
No Results Yet
NCT06641089 | RECRUITING | PHASE3
600 Participants

Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-10-15
Completion: 2027-01-15
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
NCT06641076 | RECRUITING | PHASE3
960 Participants

Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis Naive to Biologic Disease-Modifying Antirheumatic Drug

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-10-15
Completion: 2027-01-15
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
NCT06639607 | NOT_YET_RECRUITING | PHASE1/PHASE2
68 Participants

PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-31
Completion: 2031-03-31
Conditions
Diffuse Midline Glioma Diffuse Midline High-grade Glioma Medulloblastoma Ependymoma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06638619 | NOT_YET_RECRUITING | NA
20 Participants

Comparative Efficacy of Saccadic and Biofeedback Training in Homonymous Hemianopia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-31
Completion: 2026-06-30
Conditions
Hemianopia, Homonymous
Interventions
BEHAVIORAL
No Results Yet
NCT06631482 | ACTIVE_NOT_RECRUITING | NA
100 Participants

Comparison Bewteen Intraoperative HPI vs. High Mean Arterial Pressure Threshold

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-09-16
Completion: 2025-10-14
Conditions
Hypotension During Surgery
Interventions
DEVICE DRUG
No Results Yet
NCT06627894 | RECRUITING | NA
300 Participants

Attenuating DEPression With Internet CBT to Slow Cognitive Decline in Older ICU Survivors(ADEPT-ICU)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-03-13
Completion: 2029-10-30
Conditions
Depression Cognitive Decline
Interventions
BEHAVIORAL
No Results Yet
NCT06625190 | RECRUITING | PHASE1/PHASE2
27 Participants

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-02-28
Completion: 2030-02-28
Conditions
Neuroblastoma Rhabdomyosarcoma Synovial Sarcoma Peripheral Nerve Sheath Tumors Clear Cell Sarcoma Alveolar Soft Part Sarcoma Desmoplastic Small Round Cell Tumor Chordoma Rhabdoid Tumor Epithelioid Sarcoma Myoepithelial Tumor Osteosarcoma Ewing Sarcoma
Interventions
DEVICE DRUG
No Results Yet
NCT06609005 | RECRUITING | PHASE1/PHASE2
84 Participants

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-01-23
Completion: 2026-04-17
Conditions
Advanced Metastatic Castration Resistant Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06608537 | RECRUITING | PHASE2
43 Participants

A Clinical Study Based on FAPI-PET/CT Technology to Predict Pathological Complete Response After Neoadjuvant Chemoradiotherapy for MSS Rectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-04-07
Completion: 2025-12-30
Conditions
Rectal Cancer
Interventions
DRUG
No Results Yet
NCT06608511 | RECRUITING
20 Participants

Liquid Biomarker Study in Melanoma and Non-Melanoma Skin Cancers

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2024-12-11
Completion: 2026-12-31
Conditions
Skin Cancer Melanoma (Skin Cancer) Basal Cell Carcinoma of Skin Basal Cell Carcinoma of Skin, Site Unspecified Cutaneous Squamous Cell Carcinoma (CSCC) Merkel Cell Carcinoma of Skin
Interventions
OTHER
No Results Yet
NCT06608498 | COMPLETED | NA
50 Participants

DMHI for At-Risk College Students

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-10-04
Completion: 2025-01-06
Conditions
Prodromal Symptoms Psychosis
Interventions
BEHAVIORAL
No Results Yet
NCT06604884 | NOT_YET_RECRUITING
118 Participants

NV PSR INSPIRE-A Pipelineâ„¢ Vantage Post Approval Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-31
Completion: 2029-08-31
Conditions
Intracranial Aneurysm
Interventions
DEVICE
No Results Yet
NCT06597396 | ACTIVE_NOT_RECRUITING | PHASE2
46 Participants

Study to Investigate the Efficacy of Abrocitinib in Adult Participants With Severe Fatigue From Post COVID Condition/Long COVID

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-12-27
Completion: 2026-03-30
Conditions
Post-COVID Condition Fatigue Symptom
Interventions
DRUG
No Results Yet
NCT06595238 | COMPLETED | PHASE2
262 Participants

A Study in Participants With Obesity or Overweight With at Least One Weight-related Comorbidity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-10-01
Completion: 2025-08-08
Conditions
Obesity or Overweight
Interventions
DRUG
No Results Yet
NCT06579521 | COMPLETED | NA
92 Participants

Real-world Experiences of Alcohol and Cognitions Over Time

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-08-18
Completion: 2025-08-31
Conditions
Alcohol Intoxication
Interventions
OTHER
No Results Yet
NCT06579144 | RECRUITING | PHASE1
24 Participants

Pharmacokinetic Comparison of Efanesoctocog Alfa vs Other EHL-rFVIII Products in Participants With Severe Haemophilia A

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-02-24
Completion: 2026-04-30
Conditions
Hemophilia A
Interventions
DRUG
No Results Yet
NCT06579118 | COMPLETED | NA
120 Participants

The Impact of Laughter Yoga on Symptom Management and Quality of Life in Postmenopausal Women

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-08-25
Completion: 2023-12-15
Conditions
Menopause
Interventions
OTHER
No Results Yet
NCT06564519 | COMPLETED | NA
12 Participants

Resident Posture Biofeedback Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-09-26
Completion: 2025-11-02
Conditions
Postural; Strain Healthy
Interventions
DEVICE
No Results Yet
NCT06564142 | ACTIVE_NOT_RECRUITING | PHASE3
605 Participants

Evaluation of Efficacy of Povetacicept in Adults With Immunoglobulin A Nephropathy (IgAN)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-08-30
Completion: 2028-01-30
Conditions
Immunoglobulin A Nephropathy
Interventions
DRUG
No Results Yet
NCT06562803 | RECRUITING | NA
60 Participants

Efficacy and Safety of Cytokine Adsorption and Plasma Exchange in Patients With ACLF and Sepsis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-09-27
Completion: 2026-09-01
Conditions
Acute-On-Chronic Liver Failure Sepsis
Interventions
DEVICE OTHER
No Results Yet
NCT06561204 | COMPLETED | NA
94 Participants

Full-mouth Electronic Toothbrush vs. Conventional Electronic Toothbrush

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-12-30
Completion: 2025-10-10
Conditions
Toothbrush Gingivitis Plaque
Interventions
DEVICE
No Results Yet
NCT06550115 | RECRUITING | NA
50 Participants

Impact of Circulating and Tissue-specific Lipids on Vascular Function and Insulin Sensitivity in Chronic Night Shift Workers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-03-01
Completion: 2028-06-30
Conditions
Circadian Rhythm Sleep Disorder of Shift Work Type Metabolic Disease Insulin Sensitivity Blood Pressure
Interventions
BEHAVIORAL
No Results Yet
NCT06541249 | RECRUITING | PHASE2
54 Participants

MethoTRExATE in MyelOpRolifErative Neoplasms (TREATMORE) Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-10-02
Completion: 2027-06-30
Conditions
Polycythemia Vera (PV) Essential Thrombocythemia (ET) Myelofibrosis (MF)
Interventions
DRUG
No Results Yet
NCT06538116 | ACTIVE_NOT_RECRUITING | PHASE2
300 Participants

A Study of Mevidalen (LY3154207) in Participants With Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-08-26
Completion: 2026-05-31
Conditions
Alzheimer Disease
Interventions
DRUG
No Results Yet
NCT06532747 | RECRUITING | NA
32 Participants

Redefining BMI: The Body, Mind, and Inflammation Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-26
Completion: 2027-03-03
Conditions
Obesity Adiposity
Interventions
BEHAVIORAL
No Results Yet
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