Clinical Trials

Showing trials with last updates posted in 2025.

NCT05669027 | RECRUITING | NA
150 Participants

Mobile Neurofeedback for Low Back Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-02
Completion: 2027-05-01
Conditions
Chronic Low Back Pain
Interventions
DEVICE
No Results Yet
NCT05668949 | WITHDRAWN | PHASE1/PHASE2
0 Participants

Phase I/II Open Label Study Evaluating the Safety and Efficacy of Combining STAT3 Inhibition (TTI-101) With Anti-PD-1 Therapy (Pembrolizumab) in Patients With Recurrent or Metastatic (RM) Head and Neck Squamous Cell Carcinoma (HNSCC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-23
Completion: 2025-09-23
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT05655520 | TERMINATED | PHASE3
153 Participants

A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Huntington's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-12-14
Completion: 2025-01-20
Conditions
Huntington's Disease
Interventions
DRUG
NCT05641155 | COMPLETED | NA
19 Participants

A Feasibility Study Evaluating the Performance of Focused Multipolar Stimulation and Sound Coding in Adults.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-02
Completion: 2025-02-06
Conditions
Hearing Impairment, Sensorineural
Interventions
DEVICE
No Results Yet
NCT05637762 | COMPLETED
13 Participants

Development of a Seizure Detection Algorithm Based on Heart Rate and Movement Analysis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-05
Completion: 2025-04-24
Conditions
Epilepsy
Interventions
OTHER
No Results Yet
NCT05635409 | ACTIVE_NOT_RECRUITING | PHASE1
8 Participants

A Trial to Determine the Safety and Tolerability of Transplanted Stem Cell Derived Dopamine Neurons to the Brains of Individuals With Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-11-30
Completion: 2027-01-31
Conditions
Parkinson Disease
Interventions
BIOLOGICAL
No Results Yet
NCT05635019 | COMPLETED | NA
105 Participants

FoodRx for Obesity Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-12-01
Completion: 2024-07-01
Conditions
Obesity Food Insecurity
Interventions
BEHAVIORAL
NCT05632627 | COMPLETED | PHASE2
43 Participants

Cannabinoids and Traumatic Brain Injury: A Randomized, Placebo Controlled Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-04-11
Completion: 2025-07-07
Conditions
Brain Injuries, Traumatic
Interventions
DRUG
No Results Yet
NCT05617326 | RECRUITING | NA
400 Participants

Screening for Abdominal Aortic Aneurysms in the General Practice by Ultraportable Ultrasound

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-02
Completion: 2027-09-01
Conditions
Abdominal Aortic Aneurysm
Interventions
OTHER
No Results Yet
NCT05612100 | RECRUITING
170 Participants

Endocrine Therapy-Induced Alopecia in Postmenopausal and Premenopausal Female Breast Cancer Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2022-07-06
Completion: 2028-06-30
Conditions
Breast Carcinoma
Interventions
OTHER
No Results Yet
NCT05611242 | RECRUITING | PHASE3
404 Participants

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-05-08
Completion: 2026-03-08
Conditions
Acute Ischemic Stroke
Interventions
PROCEDURE
No Results Yet
NCT05603650 | RECRUITING | NA
200 Participants

Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-09-01
Completion: 2027-12-31
Conditions
Oral Bacterial Infection Oral Infection Microbial Colonization Viral Infection
Interventions
OTHER
No Results Yet
NCT05603026 | RECRUITING | NA
90 Participants

MRI in Transcatheter Aortic Valve Replacement Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-11-21
Completion: 2026-12-30
Conditions
Aortic Valve Stenosis
Interventions
DEVICE
No Results Yet
NCT05594238 | RECRUITING | NA
400 Participants

Leveraging Virtual Care Strategies to Improve Access and Treatment for Individuals With Alcohol Use Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-08-07
Completion: 2027-02-28
Conditions
Alcohol Use Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT05593523 | ACTIVE_NOT_RECRUITING
100 Participants

Fluorescence-based Detection of Inflammation and Necrosis to Inform Surgical Decision-making and Enhance Outcomes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-09
Completion: 2027-03-31
Conditions
Burn Wound
Interventions
DRUG DEVICE
No Results Yet
NCT05592990 | ACTIVE_NOT_RECRUITING | PHASE2
45 Participants

A Study to Investigate the Safety, Tolerability and Preliminary Efficacy of NGI226 Microparticles in Patients With Achilles Tendinopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-14
Completion: 2026-01-27
Conditions
Achilles Tendinopathy
Interventions
DRUG
No Results Yet
NCT05569239 | ACTIVE_NOT_RECRUITING | PHASE2
2850 Participants

Efficacy, Immunogenicity and Safety of OVX836 Influenza Vaccine 480μg

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-08
Completion: 2026-05-29
Conditions
Influenza
Interventions
BIOLOGICAL
No Results Yet
NCT05566574 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
49 Participants

A Study of RP-3500 in Combination With Standard Radiation Therapy in People With Solid Tumor Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-09-30
Completion: 2026-09-30
Conditions
Solid Tumor Metastatic Cancer
Interventions
DRUG RADIATION
No Results Yet
NCT05560477 | RECRUITING | PHASE1/PHASE2
74 Participants

Study to Evaluate the Safety and Efficacy of AM3101 to Augment Meniscal Healing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-04-26
Completion: 2026-01-31
Conditions
Meniscus Tear
Interventions
DRUG
No Results Yet
NCT05550727 | ACTIVE_NOT_RECRUITING | NA
342 Participants

The PorchLight Project

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-09-23
Completion: 2026-10-30
Conditions
Memory Loss Alzheimer Disease Dementia
Interventions
OTHER
No Results Yet
NCT05549219 | COMPLETED | PHASE2
27 Participants

24-Week Study to Assess the PD, Safety, Tolerability, and PK of GLM101 in Participants With PMM2-CDG

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-11-29
Completion: 2025-11-04
Conditions
Pmm2-CDG Phosphomannomutase 2 Deficiency
Interventions
DRUG
No Results Yet
NCT05524051 | TERMINATED | PHASE2
98 Participants

A Multi-center Study to Evaluate the Safety, Tolerability and Efficacy of TIN816 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-03
Completion: 2025-03-26
Conditions
Acute Kidney Injury Following Cardiac Surgery
Interventions
DRUG OTHER
No Results Yet
NCT05520567 | RECRUITING | PHASE1/PHASE2
70 Participants

A Study of Gilteritinib, Venetoclax and Azacitidine as a Combined Treatment for People Newly Diagnosed With Acute Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-01-31
Completion: 2028-07-31
Conditions
Acute Myeloid Leukemia (AML) FLT3-mutated Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
NCT05507879 | RECRUITING
300 Participants

TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2022-09-26
Completion: 2026-09-01
Conditions
Breast Carcinoma Cardiomyopathy Congestive Heart Failure
Interventions
PROCEDURE OTHER
No Results Yet
NCT05496998 | RECRUITING | NA
400 Participants

Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-02-07
Completion: 2029-08-31
Conditions
Mitral Regurgitation
Interventions
DEVICE
No Results Yet
NCT05493605 | RECRUITING | NA
150 Participants

Cardiac Involvement in Wilson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-02
Completion: 2026-03-31
Conditions
Wilson's Disease
Interventions
PROCEDURE
No Results Yet
NCT05491915 | ACTIVE_NOT_RECRUITING | NA
50 Participants

The MONARCH Case Series Study: SPRINT® Peripheral Nerve Stimulation for the Treatment of Head Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-10-24
Completion: 2027-08-31
Conditions
Cervicogenic Headache Occipital Neuralgia
Interventions
DEVICE
No Results Yet
NCT05488431 | RECRUITING | PHASE2
121 Participants

Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-01
Completion: 2028-03-01
Conditions
Dyslipidemias Cardiovascular Diseases HIV Infections Atherosclerosis
Interventions
DRUG OTHER
No Results Yet
NCT05485155 | RECRUITING | PHASE2
15 Participants

Zemaira Eosinophilic Esophagitis Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-05-15
Completion: 2026-10-31
Conditions
Eosinophilic Esophagitis
Interventions
DRUG
No Results Yet
NCT05482958 | COMPLETED
210 Participants

DECIDE-CV Using AI

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2022-07-29
Completion: 2025-09-15
Conditions
Type 2 Diabetes
Interventions
DEVICE
No Results Yet
NCT05481879 | RECRUITING | PHASE1/PHASE2
116 Participants

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-09-05
Completion: 2029-07-31
Conditions
Myotonic Dystrophy Type 1 (DM1)
Interventions
DRUG
No Results Yet
NCT05477082 | ACTIVE_NOT_RECRUITING
27 Participants

Blood Biomarkers in Pediatric Kidney Transplant Recipients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2023-08-21
Completion: 2025-11-16
Conditions
Rejection of Kidney Allograft
Interventions
OTHER
No Results Yet
NCT05472948 | RECRUITING | PHASE2
36 Participants

Surufatinib and Sintilimab in Combination With Capecitabine for Metastatic Adenocarcinoma of Small Intestine or Appendix Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-02-01
Completion: 2027-12-30
Conditions
Adenocarcinoma of Small Intestine Appendix Carcinoma Metastatic
Interventions
DRUG
No Results Yet
NCT05471856 | RECRUITING | PHASE1
66 Participants

A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-02-24
Completion: 2028-09-13
Conditions
Solid Tumors
Interventions
DRUG
No Results Yet
NCT05470699 | ACTIVE_NOT_RECRUITING | NA
34 Participants

RefleXion PET/CT Imaging Performance in Patients With Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-08-29
Completion: 2023-03-29
Conditions
Prostate Carcinoma
Interventions
PROCEDURE OTHER DEVICE
NCT05470322 | WITHDRAWN | NA
0 Participants

Efficacy and Tolerability of a Fractional Ablative Erbium Laser for Axillary Scarring for Hidradenitis Suppurativa Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-31
Completion: 2027-07-31
Conditions
Hidradenitis Suppurativa Scarring
Interventions
DEVICE
No Results Yet
NCT05463887 | ACTIVE_NOT_RECRUITING | NA
660 Participants

Personalized Disease Prevention

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-08-05
Completion: 2026-01-31
Conditions
Primary Prevention Healthy Aging Quality of Life Decision Support Techniques
Interventions
BEHAVIORAL
No Results Yet
NCT05460676 | RECRUITING | NA
46 Participants

Reducing Tobacco Smoking: a Transcranial Direct Current Stimulation (TDCS) Telehealth Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-08-15
Completion: 2026-04-30
Conditions
Smoking Cessation
Interventions
DEVICE OTHER
No Results Yet
NCT05451589 | ACTIVE_NOT_RECRUITING | NA
456 Participants

A Trial of a Positive Psychology Intervention for Older Adults (RESET)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-01
Completion: 2026-06-30
Conditions
Depressive Symptoms Anxiety Chronic Pain Fatigue Loneliness Stress, Psychological
Interventions
BEHAVIORAL
No Results Yet
NCT05450965 | RECRUITING | PHASE2
37 Participants

Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-07-19
Completion: 2027-08-31
Conditions
Small-cell Lung Cancer Small Cell Lung Carcinoma
Interventions
DRUG
No Results Yet
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