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Clinical Trials

Showing trials with last updates posted in 2025.

NCT05611242 | RECRUITING | PHASE3
404 Participants

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-05-08
Completion: 2026-03-08
Conditions
Acute Ischemic Stroke
Interventions
PROCEDURE
No Results Yet
NCT05603650 | RECRUITING | NA
200 Participants

Effects of Mouthrinse on the Microbiome of the Oral Cavity and GI Tract

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2021-09-01
Completion: 2027-12-31
Conditions
Oral Bacterial Infection Oral Infection Microbial Colonization Viral Infection
Interventions
OTHER
No Results Yet
NCT05603026 | RECRUITING | NA
90 Participants

MRI in Transcatheter Aortic Valve Replacement Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-11-21
Completion: 2026-12-30
Conditions
Aortic Valve Stenosis
Interventions
DEVICE
No Results Yet
NCT05594238 | RECRUITING | NA
400 Participants

Leveraging Virtual Care Strategies to Improve Access and Treatment for Individuals With Alcohol Use Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-08-07
Completion: 2027-02-28
Conditions
Alcohol Use Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT05593523 | ACTIVE_NOT_RECRUITING
100 Participants

Fluorescence-based Detection of Inflammation and Necrosis to Inform Surgical Decision-making and Enhance Outcomes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-09
Completion: 2027-03-31
Conditions
Burn Wound
Interventions
DRUG DEVICE
No Results Yet
NCT05592990 | ACTIVE_NOT_RECRUITING | PHASE2
45 Participants

A Study to Investigate the Safety, Tolerability and Preliminary Efficacy of NGI226 Microparticles in Patients With Achilles Tendinopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-14
Completion: 2026-01-27
Conditions
Achilles Tendinopathy
Interventions
DRUG
No Results Yet
NCT05569239 | ACTIVE_NOT_RECRUITING | PHASE2
2850 Participants

Efficacy, Immunogenicity and Safety of OVX836 Influenza Vaccine 480μg

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-08
Completion: 2026-05-29
Conditions
Influenza
Interventions
BIOLOGICAL
No Results Yet
NCT05566574 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
49 Participants

A Study of RP-3500 in Combination With Standard Radiation Therapy in People With Solid Tumor Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-09-30
Completion: 2026-09-30
Conditions
Solid Tumor Metastatic Cancer
Interventions
DRUG RADIATION
No Results Yet
NCT05560477 | RECRUITING | PHASE1/PHASE2
74 Participants

Study to Evaluate the Safety and Efficacy of AM3101 to Augment Meniscal Healing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-04-26
Completion: 2026-01-31
Conditions
Meniscus Tear
Interventions
DRUG
No Results Yet
NCT05550727 | ACTIVE_NOT_RECRUITING | NA
342 Participants

The PorchLight Project

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-09-23
Completion: 2026-10-30
Conditions
Memory Loss Alzheimer Disease Dementia
Interventions
OTHER
No Results Yet
NCT05549219 | COMPLETED | PHASE2
27 Participants

24-Week Study to Assess the PD, Safety, Tolerability, and PK of GLM101 in Participants With PMM2-CDG

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-11-29
Completion: 2025-11-04
Conditions
Pmm2-CDG Phosphomannomutase 2 Deficiency
Interventions
DRUG
No Results Yet
NCT05524051 | TERMINATED | PHASE2
98 Participants

A Multi-center Study to Evaluate the Safety, Tolerability and Efficacy of TIN816 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-03
Completion: 2025-03-26
Conditions
Acute Kidney Injury Following Cardiac Surgery
Interventions
DRUG OTHER
No Results Yet
NCT05520567 | RECRUITING | PHASE1/PHASE2
70 Participants

A Study of Gilteritinib, Venetoclax and Azacitidine as a Combined Treatment for People Newly Diagnosed With Acute Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-01-31
Completion: 2028-07-31
Conditions
Acute Myeloid Leukemia (AML) FLT3-mutated Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
NCT05507879 | RECRUITING
300 Participants

TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2022-09-26
Completion: 2026-09-01
Conditions
Breast Carcinoma Cardiomyopathy Congestive Heart Failure
Interventions
PROCEDURE OTHER
No Results Yet
NCT05496998 | RECRUITING | NA
400 Participants

Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-02-07
Completion: 2029-08-31
Conditions
Mitral Regurgitation
Interventions
DEVICE
No Results Yet
NCT05493605 | RECRUITING | NA
150 Participants

Cardiac Involvement in Wilson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-02
Completion: 2026-03-31
Conditions
Wilson's Disease
Interventions
PROCEDURE
No Results Yet
NCT05491915 | ACTIVE_NOT_RECRUITING | NA
50 Participants

The MONARCH Case Series Study: SPRINT® Peripheral Nerve Stimulation for the Treatment of Head Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-10-24
Completion: 2027-08-31
Conditions
Cervicogenic Headache Occipital Neuralgia
Interventions
DEVICE
No Results Yet
NCT05488431 | RECRUITING | PHASE2
121 Participants

Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-01
Completion: 2028-03-01
Conditions
Dyslipidemias Cardiovascular Diseases HIV Infections Atherosclerosis
Interventions
DRUG OTHER
No Results Yet
NCT05485155 | RECRUITING | PHASE2
15 Participants

Zemaira Eosinophilic Esophagitis Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-05-15
Completion: 2026-10-31
Conditions
Eosinophilic Esophagitis
Interventions
DRUG
No Results Yet
NCT05482958 | COMPLETED
210 Participants

DECIDE-CV Using AI

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2022-07-29
Completion: 2025-09-15
Conditions
Type 2 Diabetes
Interventions
DEVICE
No Results Yet
NCT05481879 | RECRUITING | PHASE1/PHASE2
116 Participants

Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-09-05
Completion: 2029-07-31
Conditions
Myotonic Dystrophy Type 1 (DM1)
Interventions
DRUG
No Results Yet
NCT05477082 | ACTIVE_NOT_RECRUITING
27 Participants

Blood Biomarkers in Pediatric Kidney Transplant Recipients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2023-08-21
Completion: 2025-11-16
Conditions
Rejection of Kidney Allograft
Interventions
OTHER
No Results Yet
NCT05472948 | RECRUITING | PHASE2
36 Participants

Surufatinib and Sintilimab in Combination With Capecitabine for Metastatic Adenocarcinoma of Small Intestine or Appendix Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-02-01
Completion: 2027-12-30
Conditions
Adenocarcinoma of Small Intestine Appendix Carcinoma Metastatic
Interventions
DRUG
No Results Yet
NCT05471856 | RECRUITING | PHASE1
66 Participants

A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-02-24
Completion: 2028-09-13
Conditions
Solid Tumors
Interventions
DRUG
No Results Yet
NCT05470699 | ACTIVE_NOT_RECRUITING | NA
34 Participants

RefleXion PET/CT Imaging Performance in Patients With Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-08-29
Completion: 2023-03-29
Conditions
Prostate Carcinoma
Interventions
PROCEDURE OTHER DEVICE
Results Available
NCT05470322 | WITHDRAWN | NA
0 Participants

Efficacy and Tolerability of a Fractional Ablative Erbium Laser for Axillary Scarring for Hidradenitis Suppurativa Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-31
Completion: 2027-07-31
Conditions
Hidradenitis Suppurativa Scarring
Interventions
DEVICE
No Results Yet
NCT05463887 | ACTIVE_NOT_RECRUITING | NA
660 Participants

Personalized Disease Prevention

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-08-05
Completion: 2026-01-31
Conditions
Primary Prevention Healthy Aging Quality of Life Decision Support Techniques
Interventions
BEHAVIORAL
No Results Yet
NCT05460676 | RECRUITING | NA
46 Participants

Reducing Tobacco Smoking: a Transcranial Direct Current Stimulation (TDCS) Telehealth Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-08-15
Completion: 2026-04-30
Conditions
Smoking Cessation
Interventions
DEVICE OTHER
No Results Yet
NCT05451589 | ACTIVE_NOT_RECRUITING | NA
456 Participants

A Trial of a Positive Psychology Intervention for Older Adults (RESET)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-01
Completion: 2026-06-30
Conditions
Depressive Symptoms Anxiety Chronic Pain Fatigue Loneliness Stress, Psychological
Interventions
BEHAVIORAL
No Results Yet
NCT05450965 | RECRUITING | PHASE2
37 Participants

Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-07-19
Completion: 2027-08-31
Conditions
Small-cell Lung Cancer Small Cell Lung Carcinoma
Interventions
DRUG
No Results Yet
NCT05444127 | RECRUITING
150 Participants

Oral Health and Wilson's Disease: SOMAWI

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2023-05-17
Completion: 2026-10-31
Conditions
Wilson Disease
Interventions
OTHER
No Results Yet
NCT05437575 | RECRUITING | PHASE3
994 Participants

Prehospital Analgesia INtervention Trial (PAIN)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-11-27
Completion: 2028-07-31
Conditions
Traumatic Injury
Interventions
DRUG
No Results Yet
NCT05427734 | COMPLETED | NA
127 Participants

Drivers of Suicide Mobile App Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-03-05
Completion: 2025-11-10
Conditions
Suicide Suicide, Attempted Suicidal Ideation Alcohol Use Disorder Alcoholism Alcohol Abuse Screening and Brief Interventions
Interventions
DEVICE
No Results Yet
NCT05421637 | COMPLETED
1506 Participants

Knowledge and Perception of Evidence-based Psychology in Latin American Psychologists

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2020-11-15
Completion: 2021-02-15
Conditions
Knowledge, Attitudes, Practice Evidence-based Psychology
No Results Yet
NCT05413551 | COMPLETED | PHASE1
73 Participants

Point-of-care Pharmacogenomic Testing to Optimize Isoniazid Dosing for Tuberculosis Prevention

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-23
Completion: 2025-04-23
Conditions
Tuberculosis Infection Isoniazid Adverse Reaction
Interventions
DRUG
No Results Yet
NCT05413135 | COMPLETED | PHASE2
418 Participants

Study of ARO-APOC3 in Adults With Dyslipidemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-07-07
Completion: 2025-09-18
Conditions
Dyslipidemias
Interventions
DRUG
No Results Yet
NCT05396222 | NOT_YET_RECRUITING | NA
18 Participants

A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar Spine

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2027-01-01
Completion: 2027-01-01
Conditions
Spinal Tumor
Interventions
DEVICE
No Results Yet
NCT05386563 | COMPLETED | NA
12 Participants

taVNS on Pupillary Response and Perceptual Learning

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-05-18
Completion: 2022-11-22
Conditions
Pupillary Response
Interventions
PROCEDURE
No Results Yet
NCT05384132 | RECRUITING | NA
76 Participants

Novel Dental Gel as an Adjunct to Scaling and Root Planing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-10-14
Completion: 2027-10-30
Conditions
Periodontal Diseases Gingival Diseases Gingival Pocket Gum Bleed Plaque, Dental
Interventions
OTHER
No Results Yet
NCT05370885 | TERMINATED | PHASE2
114 Participants

VE202 in Patients With Mild-to-Moderate Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-05-08
Completion: 2025-08-29
Conditions
Ulcerative Colitis Colitis, Ulcerative
Interventions
BIOLOGICAL DRUG OTHER
No Results Yet
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