Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
150 participants
OBSERVATIONAL
2023-05-17
2026-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Cases
patients with hepatic form of Wilson disease and those with neurological form
Saliva samples
A saliva sample is added by research for all patients, as well as an oral quality of life questionnaire. For the witnesses, participation also entails the completion of the standardized oral examination (potentially longer than the assessment that would have been carried out as part of the treatment) and the administration of the oral quality of life questionnaire.
Questionnaire OHIP-14
A saliva sample is added by research for all patients, as well as an oral quality of life questionnaire. For the witnesses, participation also entails the completion of the standardized oral examination (potentially longer than the assessment that would have been carried out as part of the treatment) and the administration of the oral quality of life questionnaire.
Thorough dental examination
A saliva sample is added by research for all patients, as well as an oral quality of life questionnaire. For the witnesses, participation also entails the completion of the standardized oral examination (potentially longer than the assessment that would have been carried out as part of the treatment) and the administration of the oral quality of life questionnaire.
controls
control population consulting in routine dental with panoramic dental imaging, outside of an emergency context
Questionnaire OHIP-14
A saliva sample is added by research for all patients, as well as an oral quality of life questionnaire. For the witnesses, participation also entails the completion of the standardized oral examination (potentially longer than the assessment that would have been carried out as part of the treatment) and the administration of the oral quality of life questionnaire.
Thorough dental examination
A saliva sample is added by research for all patients, as well as an oral quality of life questionnaire. For the witnesses, participation also entails the completion of the standardized oral examination (potentially longer than the assessment that would have been carried out as part of the treatment) and the administration of the oral quality of life questionnaire.
Interventions
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Saliva samples
A saliva sample is added by research for all patients, as well as an oral quality of life questionnaire. For the witnesses, participation also entails the completion of the standardized oral examination (potentially longer than the assessment that would have been carried out as part of the treatment) and the administration of the oral quality of life questionnaire.
Questionnaire OHIP-14
A saliva sample is added by research for all patients, as well as an oral quality of life questionnaire. For the witnesses, participation also entails the completion of the standardized oral examination (potentially longer than the assessment that would have been carried out as part of the treatment) and the administration of the oral quality of life questionnaire.
Thorough dental examination
A saliva sample is added by research for all patients, as well as an oral quality of life questionnaire. For the witnesses, participation also entails the completion of the standardized oral examination (potentially longer than the assessment that would have been carried out as part of the treatment) and the administration of the oral quality of life questionnaire.
Eligibility Criteria
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Inclusion Criteria
* Member of or beneficiary of a social security scheme
* For cases: Affected by Wilson's disease
* For controls: Benefiting from a first routine dental consultation with dental panoramic imaging, outside of an emergency context or treatment follow-up/maintenance
Exclusion Criteria
* Pregnant or breastfeeding women
* Severe psychiatric disorders with behavioral disorders
* For cases:
* hepatic or neurological decompensation
* liver transplant patient
* For witnesses:
* Patient with hepatic or neurological disease
* Patient taking dietary supplements enriched with copper or zinc or zinc supplementation
* Patient wearing removable prostheses with zinc-enriched prosthetic adhesives (Fixodent ProPlus®)
18 Years
ALL
Yes
Sponsors
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Fondation Ophtalmologique Adolphe de Rothschild
NETWORK
Responsible Party
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Principal Investigators
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Marjolaine GOSSET
Role: STUDY_DIRECTOR
Hopital Charles Foix
Locations
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Hopital Charles Foix
Ivry-sur-Seine, , France
Hôpital Charles Foix
Ivry-sur-Seine, , France
Fondation Adolphe de Rothschild
Paris, , France
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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APS_2022_5
Identifier Type: -
Identifier Source: org_study_id