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Clinical Trials

Showing trials with last updates posted in 2025.

NCT04948866 | COMPLETED | NA
884 Participants

Palliative Care for Persons With Late-stage Alzheimer's and Related Dementias and Their Caregivers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-07-26
Completion: 2025-02-01
Conditions
Dementia Dementia, Vascular Dementia With Lewy Bodies Dementia Frontal Dementia, Mixed Dementia Alzheimers Alzheimer Disease Dementia Severe
Interventions
BEHAVIORAL
Results Available
NCT04908735 | RECRUITING | PHASE2
40 Participants

Ruxolitinib for Early Lung Dysfunction After Hematopoietic Stem Cell Transplant

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-11-12
Completion: 2028-11-30
Conditions
Hematopoietic Stem Cell Transplant (HSCT) Bronchiolitis Obliterans (BO)
Interventions
DRUG
No Results Yet
NCT04858009 | RECRUITING | PHASE2
40 Participants

Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-02-15
Completion: 2029-07-31
Conditions
Metastatic Pancreatic Carcinoma Stage IV Pancreatic Cancer AJCC v8 Metastatic Malignant Neoplasm in the Peritoneum
Interventions
DRUG PROCEDURE
No Results Yet
NCT04799860 | COMPLETED | NA
12000 Participants

Act in Time -Implementation of Health Promotive Work-way in Primary Care Setting (AcTi)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-03-30
Completion: 2024-12-31
Conditions
Health Knowledge, Attitudes, Practice
Interventions
BEHAVIORAL
No Results Yet
NCT04779216 | COMPLETED | PHASE3
30 Participants

Effects of Romosozumab on Bone Density in Women With Anorexia Nervosa

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-09-20
Completion: 2024-10-24
Conditions
Bone Density, Low Bone Loss Anorexia Nervosa Eating Disorders
Interventions
DRUG
Results Available
NCT04765709 | TERMINATED | PHASE2
10 Participants

Durvalumab and Chemotherapy Induction Followed by Durvalumab and Radiotherapy in Large Volume Stage III NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-09-24
Completion: 2025-01-30
Conditions
Non-small Cell Lung Cancer Stage III
Interventions
COMBINATION_PRODUCT BIOLOGICAL
No Results Yet
NCT04763317 | RECRUITING
3000 Participants

Precision Medicine in the Prostate Cancer Care Pathway

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2019-02-14
Completion: 2029-12-31
Conditions
Prostate Cancer Genetic Predisposition
Interventions
GENETIC
No Results Yet
NCT04745949 | RECRUITING | PHASE2
31 Participants

PACIFIC: Primary Mediastinal Large B-cell Lymphoma Treated With Antibody Therapy, Checkpoint Inhibitor in Frontline With ImmunoChemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-05-10
Completion: 2027-08-03
Conditions
Ann Arbor Stage I Primary Mediastinal (Thymic) Large B-Cell Lymphoma Ann Arbor Stage II Primary Mediastinal (Thymic) Large B-Cell Lymphoma Ann Arbor Stage III Primary Mediastinal (Thymic) Large B-Cell Lymphoma Ann Arbor Stage IV Primary Mediastinal (Thymic) Large B-Cell Lymphoma
Interventions
DRUG BIOLOGICAL OTHER
No Results Yet
NCT04731519 | RECRUITING | NA
57 Participants

Development of a Recovery Oriented Treatment for Post-Acute Suicidal Episode (PASE) Veterans

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2022-02-22
Completion: 2025-12-25
Conditions
Suicide
Interventions
BEHAVIORAL
No Results Yet
NCT04725630 | COMPLETED | NA
597 Participants

Healthy Food Prescription Incentive Program

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-05-29
Completion: 2024-02-28
Conditions
Diet, Healthy Diabetes Mellitus, Type 2 Diabetes Complications
Interventions
BEHAVIORAL
No Results Yet
NCT04722341 | RECRUITING | NA
175 Participants

Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and Moderators

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2022-01-01
Completion: 2026-06-30
Conditions
Colorectal Cancer Breast Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT04707937 | COMPLETED | NA
150 Participants

Evaluation of a Brachytherapy Discharge Education Program to Improve Patient Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-08-19
Completion: 2025-12-05
Conditions
Gynecologic Cancer
Interventions
OTHER
No Results Yet
NCT04702802 | COMPLETED | NA
36 Participants

Study to Evaluate the Safety of the Viscoelastic Substance PRO-149, Compared to Healon® EndoCoat.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-09-07
Completion: 2021-10-29
Conditions
Age-related Cataract Phacoemulsification
Interventions
DEVICE
Results Available
NCT04692818 | RECRUITING | NA
125 Participants

3D Ultrasound Breast Imaging

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-11-10
Completion: 2026-12-31
Conditions
Breast Tumor
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04692597 | TERMINATED | NA
83 Participants

Low Level Laser Therapy (LLLT) for the Treatment of Hand Osteoarthritis.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-03-02
Completion: 2025-12-09
Conditions
Low Level Laser Therapy Osteoarthritis Family Medicine Pain Management Integrative Medicine
Interventions
DEVICE
No Results Yet
NCT04686799 | ACTIVE_NOT_RECRUITING | PHASE1
25 Participants

Doxycycline for Elbow Tendinopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-12-03
Completion: 2026-01-31
Conditions
Lateral Epicondylitis Lateral Epicondylitis, Left Elbow Lateral Epicondylitis, Right Elbow Lateral Epicondylitis, Unspecified Elbow Lateral Epicondylitis (Tennis Elbow) Bilateral Medial Epicondylitis Medial Epicondylitis, Right Elbow Medial Epicondylitis, Left Elbow
Interventions
DRUG
No Results Yet
NCT04683848 | COMPLETED | PHASE2
72 Participants

Study to Assess the Efficacy and Safety of MT-3921 in Subjects With Acute Traumatic Cervical Spinal Cord Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-08-27
Completion: 2024-12-24
Conditions
Spinal Cord Injury
Interventions
BIOLOGICAL
No Results Yet
NCT04634812 | COMPLETED | PHASE1
7 Participants

Mass Balance Study of KBP-5074 in Healthy Male Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-12-03
Completion: 2020-12-23
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT04622150 | ACTIVE_NOT_RECRUITING | NA
190 Participants

Effectiveness RCT of Customized Adherence Enhancement

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2022-02-01
Completion: 2026-03-31
Conditions
Bipolar Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT04606537 | COMPLETED | PHASE1
24 Participants

Drug to Drug Interaction Study of KBP-5074 in Healthy Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-10-24
Completion: 2020-11-30
Conditions
Healthy Drug Drug Interaction
Interventions
DRUG
No Results Yet
NCT04594369 | COMPLETED | PHASE3
1767 Participants

A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-12-01
Completion: 2024-10-28
Conditions
Non-Cystic Fibrosis Bronchiectasis
Interventions
DRUG
Results Available
NCT04586023 | ACTIVE_NOT_RECRUITING | PHASE3
751 Participants

Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Teriflunomide in Relapsing Multiple Sclerosis (RMS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-03-24
Completion: 2025-09-05
Conditions
Relapsing Multiple Sclerosis
Interventions
DRUG
No Results Yet
NCT04577911 | RECRUITING
248 Participants

How is Social Connection Represented in the Brain?

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2021-04-01
Completion: 2026-11-30
Conditions
Loneliness
Interventions
OTHER
No Results Yet
NCT04575740 | COMPLETED | NA
209 Participants

Phenotyping Mechanistic Pathways for Adverse Health Outcomes in Sleep Apnea

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-09-10
Completion: 2025-06-30
Conditions
Sleep Apnea
Interventions
DEVICE
No Results Yet
NCT04565925 | RECRUITING | PHASE2
24 Participants

Sildenafil for Treatment of Urinary Incontinence in Patients With Spinal Cord Injuries

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-07-07
Completion: 2026-12-01
Conditions
Spinal Cord Injuries Urinary Incontinence
Interventions
DRUG
No Results Yet
NCT04534699 | COMPLETED | PHASE1
12 Participants

Pharmacokinetics of KBP-5074 in Patients With Moderate Hepatic Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-08-27
Completion: 2020-11-19
Conditions
Moderate Hepatic Impairment Healthy
Interventions
DRUG
No Results Yet
NCT04491045 | COMPLETED | NA
1382 Participants

Implementation Strategies for Task-Shifting Depression Care Depression Care in Vietnam

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2021-12-01
Completion: 2025-04-30
Conditions
Depression
Interventions
OTHER
No Results Yet
NCT04445064 | TERMINATED | PHASE2
17 Participants

Activity and Safety of Peptide-based Immunotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-08-14
Completion: 2024-06-08
Conditions
Oropharynx Squamous Cell Carcinoma Larynx Squamous Cell Carcinoma Hypopharynx Squamous Cell Carcinoma Oral Cavity Squamous Cell Carcinoma
Interventions
BIOLOGICAL
No Results Yet
NCT04427293 | RECRUITING | PHASE1
12 Participants

Preoperative Lenvatinib Plus Pembrolizumab in Early-Stage Triple-Negative Breast Cancer (TNBC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-07-09
Completion: 2026-07-31
Conditions
Triple Negative Breast Cancer
Interventions
DRUG
No Results Yet
NCT04308928 | COMPLETED
332 Participants

Evaluation of New Biomarker-based Approaches for Improving the Diagnosis of Childhood Tuberculous Meningitis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2020-04-01
Completion: 2024-10-31
Conditions
Tuberculous Meningitis
No Results Yet
NCT04261686 | COMPLETED | NA
100 Participants

Post Approval Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-07-03
Completion: 2025-09-16
Conditions
Arteriovenous Fistula
Interventions
DEVICE
No Results Yet
NCT04247620 | COMPLETED | PHASE2
144 Participants

DiaBetter Together for Young Adults With Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-12-15
Completion: 2024-09-30
Conditions
Type 1 Diabetes
Interventions
BEHAVIORAL
Results Available
NCT04236908 | COMPLETED | NA
276 Participants

Accessible Acupuncture for the Warrior With Acute Low Back Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-08-25
Completion: 2025-12-09
Conditions
Acupuncture Low Back Pain
Interventions
DEVICE DRUG
No Results Yet
NCT04234139 | ENROLLING_BY_INVITATION
300 Participants

Cohort/Ethics Study of Patients With Severe Alcoholic Hepatitis Undergoing Early Liver Transplantation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2020-04-01
Completion: 2028-12-31
Conditions
Liver Diseases, Alcoholic Alcohol-Related Disorders Transplant; Failure, Liver Transplant; Complication, Rejection Liver Diseases Hepatitis, Alcoholic Alcohol-Induced Disorders
Interventions
PROCEDURE
No Results Yet
NCT04224493 | RECRUITING | PHASE3
612 Participants

A Study to Assess the Efficacy, Safety, Pharmacodynamics, and Pharmacokinetics of Tazemetostat in Combination With Lenalidomide Plus Rituximab Versus Placebo in Combination With Lenalidomide Plus Rituximab in Adult Patients at Least 18 Years of Age With Relapsed/Refractory Follicular Lymphoma.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-06-11
Completion: 2026-03-01
Conditions
Relapsed/Refractory Follicular Lymphoma Follicular Lymphoma Refractory Follicular Lymphoma
Interventions
DRUG COMBINATION_PRODUCT
No Results Yet
NCT04214119 | RECRUITING
2500 Participants

EsophaCap for the Detection of Early Esophageal Carcinoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2016-01-12
Completion: 2028-12-19
Conditions
Barrett Esophagus Esophageal Cancer Gastric Cancer
No Results Yet
NCT04207086 | ACTIVE_NOT_RECRUITING | PHASE2
21 Participants

A Phase II Study of Neoadjuvant Pembrolizumab & Lenvatinib for Resectable Stage III Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-11-11
Completion: 2023-01-31
Conditions
Melanoma Stage III
Interventions
DRUG
No Results Yet
NCT04193410 | COMPLETED
315 Participants

Healthy Childcare Centre of the Future

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2020-06-15
Completion: 2023-06-28
Conditions
Health and Wellbeing of Primary School-aged Children
Interventions
BEHAVIORAL
Results Available
NCT04191551 | RECRUITING
600 Participants

The GAstric Precancerous Conditions Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2018-07-30
Completion: 2028-06-30
Conditions
Gastric Cancer Intestinal Metaplasia of Gastric Mucosa Helicobacter Pylori Infection Atrophic Gastritis
No Results Yet
NCT04190680 | COMPLETED | NA
226 Participants

Kokkerelli Learning Street Effect Evaluation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2020-03-15
Completion: 2022-08-31
Conditions
Fruit and Vegetable Consumption in Children
Interventions
BEHAVIORAL
Results Available
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