Clinical Trials
Showing trials with last updates posted in 2025.
245
Participants
Ipilimumab With or Without Sargramostim in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2010-12-28
Completion:
2013-02-15
Conditions
Advanced Melanoma
Metastatic Melanoma
Recurrent Melanoma
Stage III Cutaneous Melanoma AJCC v7
Stage IIIA Cutaneous Melanoma AJCC v7
Stage IIIB Cutaneous Melanoma AJCC v7
Stage IIIC Cutaneous Melanoma AJCC v7
Stage IV Cutaneous Melanoma AJCC v6 and v7
Unresectable Melanoma
Interventions
BIOLOGICAL
18
Participants
Positron Emission Tomography in Women With Advanced HER2-Positive Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2011-03-16
Completion:
2018-10-23
Conditions
Breast Cancer
Stage IV Breast Cancer
Interventions
PROCEDURE
RADIATION
OTHER
GENETIC
20
Participants
Fetal Endotracheal Occlusion (FETO) in Severe and Extremely Severe Congenital Diaphragmatic Hernia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2012-02-21
Completion:
2023-04-11
Conditions
Congenital Diaphragmatic Hernia
Interventions
DEVICE
No Results Yet
60
Participants
Effectiveness of Atomoxetine in Treating ADHD Symptoms in Children and Adolescents With Autism
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-14
Start Date:
2007-07-31
Completion:
2015-10-31
Conditions
Autism
Interventions
DRUG
1000
Participants
A Natural History Study of Bone and Mineral Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-14
Start Date:
2001-11-19
Conditions
Tumor Induced Osteomalcia
Osteomalacia
Familial Tumoral Calcinosis
No Results Yet
30
Participants
Open-Label Extension Protocol to SNK01-AD01 Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-06-30
Completion:
2028-04-30
Conditions
Alzheimer Disease
Interventions
BIOLOGICAL
No Results Yet
746
Participants
Pharmacy-led Intervention to Increase the Adoption of Fixed-dose Single Pill Blood Pressure Lowering Medications: A Pragmatic RCT
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2026-01-15
Completion:
2026-08-01
Conditions
Hypertension
Primary Care
Interventions
BEHAVIORAL
No Results Yet
182
Participants
Giving Asthmatics Intramuscular Steroids for Preventing Return to the Emergency Department
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2026-01-30
Completion:
2026-06-30
Conditions
Asthma
Interventions
DRUG
No Results Yet
75
Participants
ESP Blocks for Posterior Spinal Fusion
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2026-01-31
Completion:
2028-01-31
Conditions
Postoperative Pain
Interventions
DRUG
No Results Yet
160
Participants
Use of fenoTRACK Device for Monitoring Changes of Fractional Exhaled Nitric Oxide (FeNO) in Uncontrolled Asthma Subjects and Controlled Asthma Subjects
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2025-09-17
Completion:
2026-09-30
Conditions
Asthma
Interventions
DEVICE
No Results Yet
87
Participants
Examining Effects of Active Plant Engagement on College Student Well-Being and Performance
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-08-22
Completion:
2025-12-12
Conditions
Perceived Stress
State Anxiety
Intrinsic Goal Orientation
Study Habits
Mood
Sleep Quality
Connectedness to Nature
Extrinsic Goal Orientation
Interventions
BEHAVIORAL
No Results Yet
820
Participants
Bundled Cancer Screening and Genetic Services Navigation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2026-05-01
Completion:
2029-10-31
Conditions
Breast Cancer Screening
Colon Cancer Screening
Genetics Predisposition
Interventions
BEHAVIORAL
No Results Yet
100
Participants
Cognitive Rehabilitation for Treatment of Anger in Veterans With TBI and PTSD
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2026-01-01
Completion:
2028-12-31
Conditions
Traumatic Brain Injury (TBI)
Posttraumatic Stress Disorder (PTSD)
Interventions
OTHER
No Results Yet
1269
Participants
Empower EI: Comparing Early Intervention Approaches to Improve Communication in Toddlers With Developmental Delays
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2026-03-31
Completion:
2030-03-31
Conditions
Developmental Delays
Interventions
BEHAVIORAL
No Results Yet
800
Participants
PROMIS and Mobility Evaluation in Sarcoma Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2025-07-01
Completion:
2030-06-30
Conditions
Sarcoma
Giant Cell Tumor of Bone
Interventions
PROCEDURE
No Results Yet
970
Participants
Sustaining Quality Physical Education for Healthy Kids
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-09-08
Completion:
2025-12-19
Conditions
Smart-Quality Physical Education
Interventions
BEHAVIORAL
No Results Yet
16
Participants
Clofutriben Pharmacokinetics in Patients With Impaired Renal Function
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-11-30
Completion:
2026-04-30
Conditions
Moderate Renal Impairment
Interventions
DRUG
No Results Yet
83
Participants
NeuroGuard: Psilocybin Trial for Preventing Chemo-induced Neuropathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2026-05-04
Completion:
2029-01-31
Conditions
Psilocybin
Neuropathy
Interventions
DRUG
OTHER
No Results Yet
100
Participants
Real-World Study of Foslevodopa/Foscarbidopa to Assess Quality of Life Outcomes in Adult Participants Earlier Within Advanced Parkinson Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2025-11-24
Completion:
2027-10-31
Conditions
Parkinson's Disease
No Results Yet
24
Participants
Secretome Treatment for Facial Rejuvenation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-11-25
Completion:
2026-11-15
Conditions
Facial Aging
Rejuvenation
Stem Cell
Stem Cell Banking
Interventions
OTHER
No Results Yet
92
Participants
L19IL2/TNF in Patients With Basal Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-12-31
Completion:
2030-12-31
Conditions
Locally Advanced Basal Cell Carcinoma
Interventions
DRUG
No Results Yet
20
Participants
A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-11-30
Completion:
2028-04-03
Conditions
Epileptic Encephalopathy
Interventions
DRUG
No Results Yet
5
Participants
Mixed-Reality Visual Attention Task for Neglect Diagnosis and Rehabilitation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-12-31
Completion:
2026-12-31
Conditions
Neglect, Sensory
Neglect, Hemispatial
Neglect, Hemisensory
Interventions
DEVICE
No Results Yet
82
Participants
A Ph II Study of the TheraBionic P1 Device in Subjects With Hormone Positive Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2026-02-28
Completion:
2027-05-22
Conditions
HER2-negative Breast Cancer
Hormone Receptor Positive Tumor
Advanced Breast Cancer
Metastatic Breast Cancer
Interventions
DEVICE
No Results Yet
560
Participants
Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-12-31
Completion:
2029-07-31
Conditions
Schizophrenia
Interventions
DRUG
No Results Yet
116
Participants
Evaluation of the Safety and Performance of the Novel Medtronic Experimental Automated Insulin Delivery System (NMX8) in People Living With Diabetes (NEXUS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2026-06-15
Completion:
2027-03-17
Conditions
Diabetes (Insulin-requiring, Type 1 or Type 2)
Interventions
DEVICE
No Results Yet
35
Participants
Tongue-out Radiation Therapy (TORT) for the Mitigation of Radiotherapy-related Toxicities in Patients With Head and Neck Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-11-30
Completion:
2027-11-30
Conditions
Head and Neck Carcinoma
Interventions
RADIATION
No Results Yet
240
Participants
B-PaLMZ for TB Meningitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2026-02-15
Completion:
2030-08-31
Conditions
Tuberculous Meningitis
Interventions
DRUG
No Results Yet
30
Participants
The Association Between Gut Microbiota Diversity and Postpartum Depression
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2025-11-30
Completion:
2026-05-31
Conditions
Depression During Pregnancy
No Results Yet
40000
Participants
Effect of Vision Centers on Access to Eye Care and Eye Health Outcomes
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2026-03-01
Completion:
2028-06-01
Conditions
Cataract Surgery
Eye Care
Glasses
Primary Eye Care
Vision Center
Eyecare Visits
Interventions
OTHER
No Results Yet
150
Participants
A Comparison of Satiety Effects Two Commercially Available Snack Bars
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-02-27
Completion:
2026-03-31
Conditions
Satiety
Interventions
OTHER
No Results Yet
90
Participants
Evaluation of the Proximal Form of Precontoured Sectional Matrix in Complex Proximal Posterior Restorations
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-01-01
Completion:
2025-11-30
Conditions
Complex Caries
Interventions
DEVICE
No Results Yet
162
Participants
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional MR
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2017-10-23
Completion:
2019-03-14
Conditions
Mitral Regurgitation
Mitral Valve Regurgitation
Interventions
DEVICE
No Results Yet
10
Participants
Feasibility, Usability and Preliminary Efficacy of Home-based FES Fro Adhesive Capsulitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-12-01
Completion:
2026-12-01
Conditions
Shoulder Adhesive Capsulitis
Interventions
DEVICE
No Results Yet
284
Participants
A Study of Botensilimab and Balstilimab for Colorectal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-11-07
Completion:
2030-11-30
Conditions
Colorectal Cancer
Interventions
DRUG
OTHER
No Results Yet
100
Participants
Improving Information Sharing Between Family Caregivers and Home Care Aides
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-12-01
Completion:
2027-02-28
Conditions
Shared Care
Interventions
OTHER
No Results Yet
1000
Participants
Effects of UPF Warning Labels on Social Media Among Teens and Young Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-12-01
Completion:
2025-12-20
Conditions
Nutrition
Healthy Diet
Food Preferences
Interventions
BEHAVIORAL
No Results Yet
50
Participants
Utility of Mucosal Impedance Device in Chronic Esophageal Disorders:
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-13
Start Date:
2025-11-20
Completion:
2027-11-01
Conditions
Gerd
Eosinophilic Esophagitis
Interventions
DEVICE
No Results Yet
676
Participants
Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-11-05
Completion:
2028-12-31
Conditions
Post Traumatic Stress Disorder
Depression
Violence
Interventions
BEHAVIORAL
OTHER
No Results Yet
162
Participants
Methadone in THA for Post-op Pain and Opioid Reduction
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-13
Start Date:
2025-12-01
Completion:
2026-12-01
Conditions
Post Operative Pain
Total Hip Arthroplasty
Interventions
DRUG
No Results Yet
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