Clinical Trials

Showing trials with last updates posted in 2025.

NCT07109739 | RECRUITING | NA
144 Participants

Dose-Response Effects of Inspiratory Muscle Strength Training on Blood Pressure and Vascular Function

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-10-24
Completion: 2027-03-31
Conditions
Systolic Hypertension Brachial Artery Flow-mediated Dilation
Interventions
DEVICE
No Results Yet
NCT07089784 | RECRUITING | PHASE1
64 Participants

Multiple Dose Study of MK-2828 in Participants With Type 2 Diabetes (MK-2828-003)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-09-22
Completion: 2026-01-12
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT07088068 | RECRUITING | PHASE3
723 Participants

A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-08-06
Completion: 2028-06-06
Conditions
Type 1 Diabetes Mellitus
Interventions
DRUG OTHER
No Results Yet
NCT07082998 | RECRUITING | NA
120 Participants

Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-09-12
Completion: 2027-07-31
Conditions
Depression Disorders Depression - Major Depressive Disorder Depression Disorder Depression Chronic Depression Depression in Adults
Interventions
BEHAVIORAL
No Results Yet
NCT07080515 | RECRUITING
50 Participants

Developing Screening Clinical Breast Examination Implementation Strategies in Nigeria

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2025-09-01
Completion: 2026-04-01
Conditions
Breast Cancer Detection
No Results Yet
NCT07068074 | NOT_YET_RECRUITING | PHASE3
428 Participants

A Randomized Phase III Study of Management of Treatment Naive Primary Melanoma in Elderly Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-12-12
Completion: 2031-01-01
Conditions
Cutaneous Melanoma
Interventions
PROCEDURE
No Results Yet
NCT07063420 | RECRUITING | NA
18 Participants

Patient Centered Multi-Agent Decision Support System (PCM-DSS) for Healthcare Providers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-10-28
Completion: 2026-07-31
Conditions
Type 2 Diabetes Treated With Insulin
Interventions
OTHER
No Results Yet
NCT07060807 | RECRUITING | PHASE3
1000 Participants

A Clinical Study of Patritumab Deruxtecan to Treat Breast Cancer (MK-1022-016)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-07-21
Completion: 2033-07-14
Conditions
Breast Neoplasms
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT07060495 | RECRUITING | PHASE3
134 Participants

RADA16 for Adult Tonsillectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-09-12
Completion: 2026-09-01
Conditions
Postoperative Pain
Interventions
DEVICE
No Results Yet
NCT07059845 | RECRUITING | PHASE2
320 Participants

A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-10-07
Completion: 2029-01-31
Conditions
Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT07054385 | RECRUITING | NA
60 Participants

I-CARE Rural Pilot: Intervention for Rural-Dwelling Dementia Caregivers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-07-01
Completion: 2026-05-31
Conditions
Caregiver Burden Alzheimer Disease
Interventions
BEHAVIORAL
No Results Yet
NCT07052903 | RECRUITING | PHASE3
1250 Participants

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-07-02
Completion: 2030-05-28
Conditions
Transthyretin Amyloidosis With Cardiomyopathy
Interventions
DRUG
No Results Yet
NCT07047690 | NOT_YET_RECRUITING | PHASE2
162 Participants

A Study of Nemolizumab for the Treatment of Adults With Systemic Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-12-15
Completion: 2026-08-07
Conditions
Systemic Sclerosis
Interventions
DRUG
No Results Yet
NCT07043738 | NOT_YET_RECRUITING | NA
160 Participants

Imaging- vs. Scalp-Targeted Accelerated TMS for Depression: The Number Needed to Scan Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2026-01-31
Completion: 2030-10-31
Conditions
Major Depressive Disorder (MDD)
Interventions
PROCEDURE
No Results Yet
NCT07037459 | RECRUITING | PHASE3
5056 Participants

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-06-25
Completion: 2028-06-30
Conditions
Heart Failure With Preserved Ejection Fraction Heart Failure With Mildly Reduced Ejection Fraction Obesity
Interventions
DRUG
No Results Yet
NCT07037433 | RECRUITING | PHASE3
12800 Participants

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-07-25
Completion: 2028-06-30
Conditions
Atherosclerotic Cardiovascular Disease Overweight Obesity
Interventions
DRUG
No Results Yet
NCT07036523 | NOT_YET_RECRUITING | PHASE2
71 Participants

A Study to Find Out Whether BI 765423 Has an Effect on Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) With or Without Standard Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-11-15
Completion: 2027-04-28
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
DRUG
No Results Yet
NCT07033494 | RECRUITING | PHASE2
340 Participants

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-07-16
Completion: 2029-04-30
Conditions
Early Alzheimer's Disease
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT07015697 | RECRUITING | PHASE1
76 Participants

A Study of Subcutaneous Trastuzumab Deruxtecan in Participants With Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-07-17
Completion: 2028-12-31
Conditions
Recurrent or Metastatic Solid Tumors
Interventions
DRUG
No Results Yet
NCT07011732 | RECRUITING | PHASE3
352 Participants

A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-07-10
Completion: 2028-11-24
Conditions
Alzheimer Disease
Interventions
DRUG
No Results Yet
NCT07005362 | RECRUITING
36 Participants

Fitbit and AI Chatbot in Sedentary Primary Care Patients With T2D

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2025-09-03
Completion: 2026-04-30
Conditions
Type 2 Diabetes Type 2 Diabetes Mellitus (T2DM) T2DM (Type 2 Diabetes Mellitus) T2D T2DM Remote Patient Monitoring Artificial Intelegence
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT07001748 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
148 Participants

Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-08-19
Completion: 2030-05-30
Conditions
Gastric Adenocarcinoma Gastroesophageal Junction Adenocarcinoma Peritoneal Carcinomatosis
Interventions
DRUG PROCEDURE
No Results Yet
NCT06993610 | RECRUITING | PHASE2
180 Participants

Tibulizumab Skin Healing and Inflammation Evaluation for Lasting Defense

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-05-16
Completion: 2026-09-30
Conditions
Hidradenitis Suppurativa (HS)
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06993155 | RECRUITING | PHASE2
200 Participants

A Clinical Trial Evaluating the Efficacy and Safety of Leflutrozole on Testicular Function in Men With Hypogonadotropic Hypogonadism (Low Serum Testosterone)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-06-27
Completion: 2026-07-31
Conditions
Hypogonadotropic Hypogonadism
Interventions
DRUG
No Results Yet
NCT06988787 | RECRUITING | NA
136 Participants

Multifaceted Intervention to Restore Resilience and Overcome Risk

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-09-12
Completion: 2028-08-01
Conditions
Military Sexual Trauma Intimate Partner Violence Brain Injury Post Traumatic Stress Disorder
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06987474 | RECRUITING
400 Participants

Capella Scientia Development Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2025-07-30
Completion: 2027-05-31
Conditions
Cataract
Interventions
DEVICE
No Results Yet
NCT06962839 | RECRUITING | PHASE2
300 Participants

A Study to Test Whether BI 1815368 Helps People With an Eye Condition Called Diabetic Macular Edema

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-06-05
Completion: 2027-09-01
Conditions
Macular Edema
Interventions
DRUG
No Results Yet
NCT06961006 | RECRUITING | PHASE2
160 Participants

A Clinical Study of V940 and Pembrolizumab (MK-3475) in People With Melanoma (V940-012/INTerpath-012)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-05-29
Completion: 2028-07-22
Conditions
Malignant Melanoma
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06957028 | RECRUITING | NA
6000 Participants

CGM for the Early Detection and Management of Hyperglycemia in Pregnancy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-05-27
Completion: 2027-11-27
Conditions
Gestational Diabetes Mellitus in Pregnancy
Interventions
OTHER
No Results Yet
NCT06955169 | NOT_YET_RECRUITING | PHASE2
153 Participants

Comparing the Radiopharmaceutical Drug, [177Lu]Lu-DOTATATE, to Standard of Care Treatment for Patients With Meningioma That Has Come Back After Prior Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-11-30
Completion: 2029-08-31
Conditions
Intracranial Meningioma
Interventions
DRUG OTHER
No Results Yet
NCT06945120 | RECRUITING | NA
128 Participants

ACT Lung Health Intervention: Phase Two

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-11-04
Completion: 2026-09-30
Conditions
Smoking Cessation Smoking Behaviors Smoking, Tobacco Smoking, Cigarette Smoking (Tobacco) Addiction
Interventions
BEHAVIORAL
No Results Yet
NCT06935370 | RECRUITING | PHASE3
4200 Participants

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-05-20
Completion: 2029-02-04
Conditions
Heart Failure
Interventions
DRUG
No Results Yet
NCT06928311 | RECRUITING | NA
24 Participants

This Study Explores Whether Adding Natural Elements Like Plants and Sunlight to Indoor Gyms Makes Exercise Feel Easier, More Enjoyable, and Improves Performance. By Comparing Workouts in Nature-inspired and Plain Gym Settings, it Aims to Find Better Ways to Design Fitness Spaces in Cities.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-04-04
Completion: 2025-11-30
Conditions
Biophilic Environmental Design Traditional Exercise Design
Interventions
OTHER
No Results Yet
NCT06926868 | RECRUITING | PHASE2/PHASE3
500 Participants

A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-09-11
Completion: 2028-03-13
Conditions
Breast Neoplasms
Interventions
DRUG
No Results Yet
NCT06923995 | RECRUITING | NA
120 Participants

Expansion and Evaluation of AI-generated Clinical Assessment (AI-COA®) of Depression and Anxiety Severity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-09-01
Completion: 2026-02-28
Conditions
Depression Disorders Anxiety Disorders
Interventions
OTHER
No Results Yet
NCT06923527 | RECRUITING | PHASE2
50 Participants

Circulating Tumor DNA

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-09-30
Completion: 2027-09-30
Conditions
ER+ Breast Cancer
Interventions
DRUG
No Results Yet
NCT06919991 | COMPLETED | PHASE1
14 Participants

Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-05-02
Completion: 2025-10-18
Conditions
Healthy Participants
Interventions
DRUG
No Results Yet
NCT06915818 | RECRUITING | NA
65 Participants

Flexagon Plus OTOLoc Colon Anastomosis in Patients Undergoing Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-03-29
Completion: 2025-12-31
Conditions
Colon Anastomosis
Interventions
DEVICE
No Results Yet
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