Capella Scientia Development Study

NCT ID: NCT06987474

Last Updated: 2025-11-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-07-30

Study Completion Date

2027-05-31

Brief Summary

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This study involves collecting biometry and aberration data using the next generation biometer, Unity DX.

Detailed Description

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In this prospective, noninterventional, single-arm, unmasked, multicenter study, 4 different subject cohorts will be enrolled simultaneously to collect biometry and aberrometry data using Unity DX. This study will be conducted in India, Spain, and the Philippines.

Conditions

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Cataract

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Group 1

Subjects/eyes previously implanted with an Alcon monofocal or multifocal presbyopia correcting IOL. Measurements will be taken with Unity DX and SMARTCataract DX (SCDX) Biometer and either the IOLMaster 700 Biometer or the Argos with Alcon Image Guidance Biometer depending on which device is used at site.

Unity DX and SMARTCataract DX (SCDX) Biometer

Intervention Type DEVICE

Unity DX is a CE-marked, noninvasive, noncontact instrument that generates a 3D model of the eye using hyper parallel optical coherence tomography (HP OCT), aberrometry, and topography. The current version of SCDX software will be used in this study.

IOLMaster 700 Biometer

Intervention Type DEVICE

The IOLMaster 700 Biometer is a CE-marked, noninvasive, noncontact instrument that captures optical biometry. Data will be collected using standard clinical assessments.

Argos with Alcon Image Guidance Biometer

Intervention Type DEVICE

The Argos with Alcon Image Guidance biometer is a CE-marked, noninvasive, noncontact instrument that will capture optical biometry. Data will be collected using standard clinical assessments.

Group 2

Subjects/eyes with planned implantation of an Alcon monofocal or monofocal toric IOL. Measurements will be taken with Unity DX and SMARTCataract DX (SCDX) Biometer and either the IOLMaster 700 Biometer or the Argos with Alcon Image Guidance Biometer depending on which device is used at site.

Unity DX and SMARTCataract DX (SCDX) Biometer

Intervention Type DEVICE

Unity DX is a CE-marked, noninvasive, noncontact instrument that generates a 3D model of the eye using hyper parallel optical coherence tomography (HP OCT), aberrometry, and topography. The current version of SCDX software will be used in this study.

IOLMaster 700 Biometer

Intervention Type DEVICE

The IOLMaster 700 Biometer is a CE-marked, noninvasive, noncontact instrument that captures optical biometry. Data will be collected using standard clinical assessments.

Argos with Alcon Image Guidance Biometer

Intervention Type DEVICE

The Argos with Alcon Image Guidance biometer is a CE-marked, noninvasive, noncontact instrument that will capture optical biometry. Data will be collected using standard clinical assessments.

Group 3

Subjects/eyes with with prior refractive surgery such as LASIK or PRK and planned implantation of an Alcon monofocal or monofocal toric IOL. Measurements will be taken with Unity DX and SMARTCataract DX (SCDX) Biometer and either the IOLMaster 700 Biometer or the Argos with Alcon Image Guidance Biometer depending on which device is used at site.

Unity DX and SMARTCataract DX (SCDX) Biometer

Intervention Type DEVICE

Unity DX is a CE-marked, noninvasive, noncontact instrument that generates a 3D model of the eye using hyper parallel optical coherence tomography (HP OCT), aberrometry, and topography. The current version of SCDX software will be used in this study.

IOLMaster 700 Biometer

Intervention Type DEVICE

The IOLMaster 700 Biometer is a CE-marked, noninvasive, noncontact instrument that captures optical biometry. Data will be collected using standard clinical assessments.

Argos with Alcon Image Guidance Biometer

Intervention Type DEVICE

The Argos with Alcon Image Guidance biometer is a CE-marked, noninvasive, noncontact instrument that will capture optical biometry. Data will be collected using standard clinical assessments.

Group 4

Subjects/eyes with keratoconus, a progressive cornea disorder. Measurements will be taken with Unity DX and SMARTCataract DX (SCDX) Biometer and either the IOLMaster 700 Biometer or the Argos with Alcon Image Guidance Biometer depending on which device is used at site.

Unity DX and SMARTCataract DX (SCDX) Biometer

Intervention Type DEVICE

Unity DX is a CE-marked, noninvasive, noncontact instrument that generates a 3D model of the eye using hyper parallel optical coherence tomography (HP OCT), aberrometry, and topography. The current version of SCDX software will be used in this study.

IOLMaster 700 Biometer

Intervention Type DEVICE

The IOLMaster 700 Biometer is a CE-marked, noninvasive, noncontact instrument that captures optical biometry. Data will be collected using standard clinical assessments.

Argos with Alcon Image Guidance Biometer

Intervention Type DEVICE

The Argos with Alcon Image Guidance biometer is a CE-marked, noninvasive, noncontact instrument that will capture optical biometry. Data will be collected using standard clinical assessments.

Interventions

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Unity DX and SMARTCataract DX (SCDX) Biometer

Unity DX is a CE-marked, noninvasive, noncontact instrument that generates a 3D model of the eye using hyper parallel optical coherence tomography (HP OCT), aberrometry, and topography. The current version of SCDX software will be used in this study.

Intervention Type DEVICE

IOLMaster 700 Biometer

The IOLMaster 700 Biometer is a CE-marked, noninvasive, noncontact instrument that captures optical biometry. Data will be collected using standard clinical assessments.

Intervention Type DEVICE

Argos with Alcon Image Guidance Biometer

The Argos with Alcon Image Guidance biometer is a CE-marked, noninvasive, noncontact instrument that will capture optical biometry. Data will be collected using standard clinical assessments.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Able to understand and sign an IRB/IEC approved consent form;
* Willing and able to attend study visit(s) as required by the protocol;
* Consenting age at the jurisdiction of study site;

Exclusion Criteria

* Women of child-bearing potential;
* Unable to fixate due to nystagmus or other eye movement abnormality (e.g., significant strabismus);
* Unclear optical media preventing data capture from all devices in the study;
* Contraindicated for pupil dilation (e.g., narrow angles, allergies) per investigator's clinical judgment;
* Any ocular disease and/or condition that, in the investigator's clinical judgment, may put the subject at significant risk, may compromise study results, or may interfere significantly with the subject's participation in the study;
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alcon Research

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Principal II, Clinical Trial Operations, Vision Care

Role: STUDY_DIRECTOR

Alcon Research, LLC

Locations

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Fort Worth, Texas, United States

Site Status NOT_YET_RECRUITING

Narayana Nethralaya

Bangalore, , India

Site Status NOT_YET_RECRUITING

Asian Eye Institute

Makati City, , Philippines

Site Status RECRUITING

Clinica Novovision - Clinica Madrid

Madrid, , Spain

Site Status NOT_YET_RECRUITING

Clinica Rementeria

Madrid, , Spain

Site Status NOT_YET_RECRUITING

Countries

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United States India Philippines Spain

Central Contacts

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Alcon Call Center

Role: CONTACT

Phone: 1-888-451-3937

Email: [email protected]

Other Identifiers

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CTK378-E006

Identifier Type: -

Identifier Source: org_study_id