Clinical Trials Updated in 2025

NCT06147037 | RECRUITING | PHASE1

70 Participants

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-07-31

Completion: 2028-05-12

Conditions

Advanced Solid Tumor Metastatic Colorectal Carcinoma Head and Neck Squamous Cell Carcinoma Non-small Cell Lung Cancer Pancreatic Ductal Adenocarcinoma Gastric Cancer Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT06115811 | NOT_YET_RECRUITING | NA

20 Participants

Radiation Treatment Plan Evaluation Learning Tool Pilot Project

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2026-01-15

Completion: 2026-11-01

Conditions

Radiation Oncology

Interventions

BEHAVIORAL

No Results Yet

NCT06113237 | RECRUITING

50 Participants

Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy

Study Type: OBSERVATIONAL

Last Updated: 2025-11-13

Start Date: 2025-08-05

Completion: 2033-08-31

Conditions

Maternal Complications Pregnancy Complication Birth Outcomes, Adverse Pregnancy

Interventions

DRUG

No Results Yet

NCT06112613 | RECRUITING | NA

410 Participants

Mobile Health for Adherence in Breast Cancer Patients

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-01-26

Completion: 2027-07-31

Conditions

Anatomic Stage IV Breast Cancer AJCC v8 Breast Carcinoma HER2-Negative Breast Carcinoma Hormone Receptor-Positive Breast Carcinoma

Interventions

OTHER PROCEDURE BEHAVIORAL

No Results Yet

NCT06096844 | RECRUITING | PHASE3

304 Participants

Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-07-19

Completion: 2026-06-01

Conditions

Advanced Lung Non-Small Cell Carcinoma Stage IIIB Lung Cancer AJCC v8 Stage IIIC Lung Cancer AJCC v8 Stage IV Lung Cancer AJCC v8

Interventions

DRUG PROCEDURE BIOLOGICAL OTHER

No Results Yet

NCT06094088 | RECRUITING | NA

120 Participants

Researching Heat and Yoga for Mood Enhancement

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-07-01

Completion: 2026-09-01

Conditions

Depression

Interventions

BEHAVIORAL

No Results Yet

NCT06090097 | RECRUITING | NA

60 Participants

Knee Biofeedback Rehabilitation Through Game Therapy

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-09-04

Completion: 2025-11-30

Conditions

Knee Osteoarthritis

Interventions

DEVICE OTHER

No Results Yet

NCT06085625 | RECRUITING | PHASE2

224 Participants

A Randomized Control Trial for Patient Reported Outcomes and Safety in Outpatient Thyroid Lobectomy

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-11-26

Completion: 2027-11-01

Conditions

Thyroid Lobectomy

Interventions

BEHAVIORAL

No Results Yet

NCT06079372 | ACTIVE_NOT_RECRUITING | PHASE3

43 Participants

Phase 3 Study of ALXN1850 in Pediatric Participants With HPP Previously Treated With Asfotase Alfa

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-04-02

Completion: 2025-07-23

Conditions

Hypophosphatasia

Interventions

DRUG

No Results Yet

NCT06079281 | ACTIVE_NOT_RECRUITING | PHASE3

124 Participants

Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-01-03

Completion: 2025-07-09

Conditions

Hypophosphatasia

Interventions

DRUG

No Results Yet

NCT06077864 | ACTIVE_NOT_RECRUITING | PHASE3

5533 Participants

A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-11-20

Completion: 2026-04-06

Conditions

Obesity

Interventions

DRUG

No Results Yet

NCT06066528 | ACTIVE_NOT_RECRUITING | PHASE3

755 Participants

A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-11-27

Completion: 2025-12-12

Conditions

Obesity Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT06063161 | COMPLETED | NA

30 Participants

Music Therapy to Prevent Hospital-acquired Delirium in Parkinson's Disease and Dementia With Lewy Bodies

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-04-01

Completion: 2025-07-01

Conditions

Parkinson Disease Dementia, Lewy Body Delirium

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT06055894 | RECRUITING | NA

200 Participants

A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-09-20

Completion: 2026-09-30

Conditions

Multiple Myeloma, Smoldering Multiple Myeloma Monoclonal Gammopathy of Undetermined Significance

Interventions

DIETARY_SUPPLEMENT OTHER

No Results Yet

NCT06054555 | RECRUITING | PHASE3

620 Participants

A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-11-02

Completion: 2028-01-25

Conditions

Melanoma

Interventions

DRUG

No Results Yet

NCT06054113 | ACTIVE_NOT_RECRUITING | PHASE2

18 Participants

Study of Blinatumomab Administration in Chinese Pediatric Participants With Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia (R/R B-ALL)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-07-23

Completion: 2025-12-26

Conditions

B Precursor Acute Lymphoblastic Leukemia Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia

Interventions

DRUG

No Results Yet

NCT06052943 | RECRUITING | NA

175 Participants

Health Without Barriers/Salud Sin Barreras

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2022-09-21

Completion: 2027-06-30

Conditions

Mental Health Wellness Family Research Lifestyle Risk Reduction

Interventions

BEHAVIORAL

No Results Yet

NCT06051617 | RECRUITING | PHASE3

318 Participants

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-09-07

Completion: 2030-08-31

Conditions

Primary Biliary Cholangitis

Interventions

DRUG

No Results Yet

NCT06051058 | RECRUITING | NA

798 Participants

Care Transitions App for Patients With Multiple Chronic Conditions

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-10-08

Completion: 2026-06-30

Conditions

Heart Failure Congestive Heart Failure Diabetes Diabetes Mellitus Chronic Kidney Diseases

Interventions

BEHAVIORAL

No Results Yet

NCT06033365 | COMPLETED | NA

192 Participants

Beginning Early and Assertive Treatment for Methamphetamine Use Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-04-11

Completion: 2024-12-31

Conditions

Methamphetamine Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06020014 | COMPLETED | PHASE2

339 Participants

Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-Severe Asthma Uncontrolled on Medium-High Dose ICS-LABA

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-11-16

Completion: 2025-10-28

Conditions

Asthma

Interventions

DRUG OTHER

No Results Yet

NCT06015737 | RECRUITING | PHASE3

302 Participants

A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-06-29

Completion: 2026-11-15

Conditions

Cutaneous Lupus Erythematosus

Interventions

COMBINATION_PRODUCT OTHER

No Results Yet

NCT06008756 | ACTIVE_NOT_RECRUITING | PHASE3

14550 Participants

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-10-09

Completion: 2029-11-29

Conditions

Arteriosclerosis Hypercholesterolaemia

Interventions

DRUG

No Results Yet

NCT06006078 | COMPLETED | NA

57 Participants

Aerosolization During Upper Endoscopy

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2021-08-31

Completion: 2021-10-15

Conditions

Infectious Gastro-Intestinal Disorder Safety Issues

Interventions

DEVICE

Results Available

NCT06004440 | RECRUITING

3000 Participants

Real World Registry for Use of the Ion Endoluminal System

Study Type: OBSERVATIONAL

Last Updated: 2025-11-13

Start Date: 2023-09-21

Completion: 2029-08-31

Conditions

Lung Cancer Multiple Pulmonary Nodules Lung Neoplasms Respiratory Tract Neoplasms Thoracic Neoplasms Neoplasms by Site Neoplasms Lung Diseases Respiratory Tract Diseases

Interventions

DEVICE

No Results Yet

NCT06004232 | ACTIVE_NOT_RECRUITING | NA

62 Participants

Prenatal Yoga to Prevent Postpartum Depression

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-02-26

Completion: 2026-03-31

Conditions

Postpartum Depression

Interventions

BEHAVIORAL

No Results Yet

NCT06002828 | RECRUITING

2000 Participants

Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

Study Type: OBSERVATIONAL

Last Updated: 2025-11-13

Start Date: 2023-10-13

Completion: 2030-02-01

Conditions

Hodgkin Lymphoma Non-Hodgkin Lymphoma

Interventions

PROCEDURE OTHER

No Results Yet

NCT05997017 | RECRUITING | PHASE2

29 Participants

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-12-28

Completion: 2026-12-31

Conditions

Endometrial Cancer Endometrioid Tumor Cancer Tumor Recurrent Endometrial Carcinoma Endometrioid Endometrial Cancer

Interventions

DRUG

No Results Yet

NCT05993611 | SUSPENDED | PHASE1

27 Participants

Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-02-19

Completion: 2028-05-21

Conditions

Chronic Graft Versus Host Disease Hematologic and Lymphocytic Disorder Steroid Refractory Graft Versus Host Disease

Interventions

PROCEDURE BIOLOGICAL OTHER

No Results Yet

NCT05987241 | RECRUITING | PHASE2/PHASE3

992 Participants

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-02-02

Completion: 2030-09-02

Conditions

Muscle Invasive Bladder Urothelial Carcinoma Muscle Invasive Renal Pelvis Urothelial Carcinoma Muscle Invasive Ureter Urothelial Carcinoma Muscle Invasive Urethral Urothelial Carcinoma Stage II Bladder Urothelial Carcinoma AJCC v6 and v7 Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 Stage IV Bladder Urothelial Carcinoma AJCC v7

Interventions

PROCEDURE OTHER BIOLOGICAL

No Results Yet

NCT05972551 | RECRUITING | PHASE3

106 Participants

Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-04-22

Completion: 2027-06-01

Conditions

Osteogenesis Imperfecta

Interventions

DRUG

No Results Yet

NCT05968742 | RECRUITING | NA

80 Participants

Variation in Gingival Inflammatory Responses

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-06-30

Completion: 2026-10-01

Conditions

Gingivitis

Interventions

BEHAVIORAL

No Results Yet

NCT05966805 | COMPLETED | NA

21 Participants

Impact of Exercise Intervention on Well-being in Shift-working Acute Care Nurses

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-09-13

Completion: 2025-05-13

Conditions

Psychological Wellness

Interventions

BEHAVIORAL

No Results Yet

NCT05954871 | COMPLETED | PHASE1

10 Participants

Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-01-08

Completion: 2025-09-16

Conditions

Colorectal Cancer Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT05949177 | RECRUITING | NA

50 Participants

Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2024-10-30

Completion: 2026-07-31

Conditions

Anterior Cruciate Ligament Injuries

Interventions

BEHAVIORAL

No Results Yet

NCT05936580 | RECRUITING | PHASE4

28 Participants

Nuwiq Dosing and Outcomes In the ManagEment of Women/Girls With Haemophilia A Needing FVIII Treatment for Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2025-12-31

Completion: 2027-02-28

Conditions

Hemophilia A

Interventions

DRUG

No Results Yet

NCT05933174 | RECRUITING | NA

220 Participants

Promoting Alternatives to Sulfonylureas to Improve Patient Safety in Type 2 Diabetes

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-10-01

Completion: 2026-06-30

Conditions

Type2diabetes

Interventions

OTHER

No Results Yet

NCT05931497 | RECRUITING | NA

21 Participants

Sauna for Long Covid

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2026-08-01

Completion: 2026-09-30

Conditions

Long COVID

Interventions

DEVICE

No Results Yet

NCT05920356 | RECRUITING | PHASE3

750 Participants

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-11-16

Completion: 2026-06-30

Conditions

Non-Small Cell Lung Cancer (NSCLC)

Interventions

DRUG

No Results Yet

NCT05912231 | ACTIVE_NOT_RECRUITING | NA

60 Participants

Ultrahypofractionation and Normal Tissue Toxicity

Study Type: INTERVENTIONAL

Last Updated: 2025-11-13

Start Date: 2023-08-15

Completion: 2026-12-31

Conditions

Breast Cancer Breast Cancer Female Breast Cancer Stage II Breast Cancer Stage III Myocardial Fibrosis

Interventions

RADIATION

No Results Yet