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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06079281 | ACTIVE_NOT_RECRUITING | PHASE3
124 Participants

Phase 3 Study of ALXN1850 Versus Placebo in Adolescent and Adult Participants With HPP Who Have Not Previously Been Treated With Asfotase Alfa

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-01-03
Completion: 2025-07-09
Conditions
Hypophosphatasia
Interventions
DRUG
No Results Yet
NCT06077864 | ACTIVE_NOT_RECRUITING | PHASE3
5533 Participants

A Study to Test the Effect of Survodutide (BI 456906) on Cardiovascular Safety in People With Overweight or Obesity (SYNCHRONIZE™ - CVOT)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-11-20
Completion: 2026-04-06
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT06066528 | ACTIVE_NOT_RECRUITING | PHASE3
755 Participants

A Study to Test Whether Survodutide (BI 456906) Helps People Living With Overweight or Obesity Who Also Have Diabetes to Lose Weight

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-11-27
Completion: 2025-12-12
Conditions
Obesity Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT06063161 | COMPLETED | NA
30 Participants

Music Therapy to Prevent Hospital-acquired Delirium in Parkinson's Disease and Dementia With Lewy Bodies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-04-01
Completion: 2025-07-01
Conditions
Parkinson Disease Dementia, Lewy Body Delirium
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06055894 | RECRUITING | NA
200 Participants

A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-09-20
Completion: 2026-09-30
Conditions
Multiple Myeloma, Smoldering Multiple Myeloma Monoclonal Gammopathy of Undetermined Significance
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT06054555 | RECRUITING | PHASE3
620 Participants

A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-11-02
Completion: 2028-01-25
Conditions
Melanoma
Interventions
DRUG
No Results Yet
NCT06054113 | ACTIVE_NOT_RECRUITING | PHASE2
18 Participants

Study of Blinatumomab Administration in Chinese Pediatric Participants With Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia (R/R B-ALL)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-07-23
Completion: 2025-12-26
Conditions
B Precursor Acute Lymphoblastic Leukemia Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia
Interventions
DRUG
No Results Yet
NCT06052943 | RECRUITING | NA
175 Participants

Health Without Barriers/Salud Sin Barreras

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-09-21
Completion: 2027-06-30
Conditions
Mental Health Wellness Family Research Lifestyle Risk Reduction
Interventions
BEHAVIORAL
No Results Yet
NCT06051617 | RECRUITING | PHASE3
318 Participants

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-09-07
Completion: 2030-08-31
Conditions
Primary Biliary Cholangitis
Interventions
DRUG
No Results Yet
NCT06051058 | RECRUITING | NA
798 Participants

Care Transitions App for Patients With Multiple Chronic Conditions

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-10-08
Completion: 2026-06-30
Conditions
Heart Failure Congestive Heart Failure Diabetes Diabetes Mellitus Chronic Kidney Diseases
Interventions
BEHAVIORAL
No Results Yet
NCT06033365 | COMPLETED | NA
192 Participants

Beginning Early and Assertive Treatment for Methamphetamine Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-04-11
Completion: 2024-12-31
Conditions
Methamphetamine Use Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06020014 | COMPLETED | PHASE2
339 Participants

Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-Severe Asthma Uncontrolled on Medium-High Dose ICS-LABA

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-11-16
Completion: 2025-10-28
Conditions
Asthma
Interventions
DRUG OTHER
No Results Yet
NCT06015737 | RECRUITING | PHASE3
302 Participants

A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-06-29
Completion: 2026-11-15
Conditions
Cutaneous Lupus Erythematosus
Interventions
COMBINATION_PRODUCT OTHER
No Results Yet
NCT06008756 | ACTIVE_NOT_RECRUITING | PHASE3
14550 Participants

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-10-09
Completion: 2029-11-29
Conditions
Arteriosclerosis Hypercholesterolaemia
Interventions
DRUG
No Results Yet
NCT06006078 | COMPLETED | NA
57 Participants

Aerosolization During Upper Endoscopy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2021-08-31
Completion: 2021-10-15
Conditions
Infectious Gastro-Intestinal Disorder Safety Issues
Interventions
DEVICE
Results Available
NCT06004440 | RECRUITING
3000 Participants

Real World Registry for Use of the Ion Endoluminal System

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2023-09-21
Completion: 2029-08-31
Conditions
Lung Cancer Multiple Pulmonary Nodules Lung Neoplasms Respiratory Tract Neoplasms Thoracic Neoplasms Neoplasms by Site Neoplasms Lung Diseases Respiratory Tract Diseases
Interventions
DEVICE
No Results Yet
NCT06004232 | ACTIVE_NOT_RECRUITING | NA
62 Participants

Prenatal Yoga to Prevent Postpartum Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-02-26
Completion: 2026-03-31
Conditions
Postpartum Depression
Interventions
BEHAVIORAL
No Results Yet
NCT06002828 | RECRUITING
2000 Participants

Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2023-10-13
Completion: 2030-02-01
Conditions
Hodgkin Lymphoma Non-Hodgkin Lymphoma
Interventions
PROCEDURE OTHER
No Results Yet
NCT05997017 | RECRUITING | PHASE2
29 Participants

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-12-28
Completion: 2026-12-31
Conditions
Endometrial Cancer Endometrioid Tumor Cancer Tumor Recurrent Endometrial Carcinoma Endometrioid Endometrial Cancer
Interventions
DRUG
No Results Yet
NCT05993611 | SUSPENDED | PHASE1
27 Participants

Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-02-19
Completion: 2028-05-21
Conditions
Chronic Graft Versus Host Disease Hematologic and Lymphocytic Disorder Steroid Refractory Graft Versus Host Disease
Interventions
PROCEDURE BIOLOGICAL OTHER
No Results Yet
NCT05987241 | RECRUITING | PHASE2/PHASE3
992 Participants

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-02-02
Completion: 2030-09-02
Conditions
Muscle Invasive Bladder Urothelial Carcinoma Muscle Invasive Renal Pelvis Urothelial Carcinoma Muscle Invasive Ureter Urothelial Carcinoma Muscle Invasive Urethral Urothelial Carcinoma Stage II Bladder Urothelial Carcinoma AJCC v6 and v7 Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 Stage IV Bladder Urothelial Carcinoma AJCC v7
Interventions
PROCEDURE OTHER BIOLOGICAL
No Results Yet
NCT05972551 | RECRUITING | PHASE3
106 Participants

Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-04-22
Completion: 2027-06-01
Conditions
Osteogenesis Imperfecta
Interventions
DRUG
No Results Yet
NCT05968742 | RECRUITING | NA
80 Participants

Variation in Gingival Inflammatory Responses

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-06-30
Completion: 2026-10-01
Conditions
Gingivitis
Interventions
BEHAVIORAL
No Results Yet
NCT05966805 | COMPLETED | NA
21 Participants

Impact of Exercise Intervention on Well-being in Shift-working Acute Care Nurses

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-09-13
Completion: 2025-05-13
Conditions
Psychological Wellness
Interventions
BEHAVIORAL
No Results Yet
NCT05954871 | COMPLETED | PHASE1
10 Participants

Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-01-08
Completion: 2025-09-16
Conditions
Colorectal Cancer Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT05949177 | RECRUITING | NA
50 Participants

Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-10-30
Completion: 2026-07-31
Conditions
Anterior Cruciate Ligament Injuries
Interventions
BEHAVIORAL
No Results Yet
NCT05936580 | RECRUITING | PHASE4
28 Participants

Nuwiq Dosing and Outcomes In the ManagEment of Women/Girls With Haemophilia A Needing FVIII Treatment for Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-12-31
Completion: 2027-02-28
Conditions
Hemophilia A
Interventions
DRUG
No Results Yet
NCT05933174 | RECRUITING | NA
220 Participants

Promoting Alternatives to Sulfonylureas to Improve Patient Safety in Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-10-01
Completion: 2026-06-30
Conditions
Type2diabetes
Interventions
OTHER
No Results Yet
NCT05931497 | RECRUITING | NA
21 Participants

Sauna for Long Covid

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2026-08-01
Completion: 2026-09-30
Conditions
Long COVID
Interventions
DEVICE
No Results Yet
NCT05920356 | RECRUITING | PHASE3
750 Participants

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-11-16
Completion: 2026-06-30
Conditions
Non-Small Cell Lung Cancer (NSCLC)
Interventions
DRUG
No Results Yet
NCT05912231 | ACTIVE_NOT_RECRUITING | NA
60 Participants

Ultrahypofractionation and Normal Tissue Toxicity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-08-15
Completion: 2026-12-31
Conditions
Breast Cancer Breast Cancer Female Breast Cancer Stage II Breast Cancer Stage III Myocardial Fibrosis
Interventions
RADIATION
No Results Yet
NCT05909761 | RECRUITING
60 Participants

Observational Safety Study in Women With Neuromyelitis Optica Spectrum Disorder (NMOSD) Exposed to UPLIZNA® During Pregnancy

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2026-01-15
Completion: 2032-10-31
Conditions
Neuromyelitis Optica Spectrum Disorder Pregnancy Related
Interventions
DRUG
No Results Yet
NCT05907122 | COMPLETED | PHASE3
256 Participants

A Study to Evaluate Similarity of ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Resected Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-07-26
Completion: 2025-10-31
Conditions
Melanoma
Interventions
DRUG
No Results Yet
NCT05904886 | ACTIVE_NOT_RECRUITING | PHASE3
687 Participants

A Study Evaluating Atezolizumab and Bevacizumab, With or Without Tiragolumab, in Participants With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) (IMbrave152)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-09-14
Completion: 2025-05-08
Conditions
Hepatocellular Carcinoma
Interventions
DRUG OTHER
No Results Yet
NCT05896254 | COMPLETED | PHASE1/PHASE2
55 Participants

Study of MAR001 in Adults With Metabolic Dysfunction

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-07-22
Completion: 2024-12-13
Conditions
Hypertriglyceridemia
Interventions
DRUG
No Results Yet
NCT05888441 | RECRUITING | NA
200 Participants

Obstacle Negotiation in Older People With and Without Vision Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-04-14
Completion: 2028-12-31
Conditions
Low Vision
Interventions
OTHER
No Results Yet
NCT05864846 | ACTIVE_NOT_RECRUITING | PHASE4
79 Participants

A Study to Investigate Behavioral and Other Co-Occurring Outcomes With Epidiolex as Add-On Therapy in Participants Aged 1 to 65 Years of Age With Tuberous Sclerosis Complex

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-06-29
Completion: 2026-03-26
Conditions
Tuberous Sclerosis Complex Associated Neuropsychiatric Disease
Interventions
DRUG
No Results Yet
NCT05863351 | RECRUITING | PHASE3
472 Participants

Focused Radiation Versus Systemic Therapy for Kidney Cancer Patients With Limited Metastasis, SOAR Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-09-07
Completion: 2030-12-01
Conditions
Metastatic Renal Cell Carcinoma Stage IV Renal Cell Cancer AJCC v8
Interventions
PROCEDURE OTHER
No Results Yet
NCT05863195 | RECRUITING | PHASE3
408 Participants

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-10-19
Completion: 2029-06-30
Conditions
Metastatic Colorectal Carcinoma Metastatic Malignant Neoplasm in the Liver Stage IV Colorectal Cancer AJCC v8 Unresectable Colorectal Carcinoma
Interventions
BIOLOGICAL PROCEDURE DRUG
No Results Yet
NCT05862727 | ACTIVE_NOT_RECRUITING | NA
46 Participants

Preschool Attention and Sleep Support (PASS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-07-24
Completion: 2026-01-31
Conditions
ADHD Psychiatric Health
Interventions
BEHAVIORAL
No Results Yet
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