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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06054555 | RECRUITING | PHASE3
620 Participants

A Study to Evaluate ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Unresectable or Metastatic Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-11-02
Completion: 2028-01-25
Conditions
Melanoma
Interventions
DRUG
No Results Yet
NCT06054113 | ACTIVE_NOT_RECRUITING | PHASE2
18 Participants

Study of Blinatumomab Administration in Chinese Pediatric Participants With Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia (R/R B-ALL)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-07-23
Completion: 2025-12-26
Conditions
B Precursor Acute Lymphoblastic Leukemia Relapsed/Refractory B Precursor Acute Lymphoblastic Leukemia
Interventions
DRUG
No Results Yet
NCT06052943 | RECRUITING | NA
175 Participants

Health Without Barriers/Salud Sin Barreras

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2022-09-21
Completion: 2027-06-30
Conditions
Mental Health Wellness Family Research Lifestyle Risk Reduction
Interventions
BEHAVIORAL
No Results Yet
NCT06051617 | RECRUITING | PHASE3
318 Participants

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-09-07
Completion: 2030-08-31
Conditions
Primary Biliary Cholangitis
Interventions
DRUG
No Results Yet
NCT06051058 | RECRUITING | NA
798 Participants

Care Transitions App for Patients With Multiple Chronic Conditions

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-10-08
Completion: 2026-06-30
Conditions
Heart Failure Congestive Heart Failure Diabetes Diabetes Mellitus Chronic Kidney Diseases
Interventions
BEHAVIORAL
No Results Yet
NCT06033365 | COMPLETED | NA
192 Participants

Beginning Early and Assertive Treatment for Methamphetamine Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-04-11
Completion: 2024-12-31
Conditions
Methamphetamine Use Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06020014 | COMPLETED | PHASE2
339 Participants

Phase 2a Study to Assess the Efficacy and Safety of AZD4604 in Adult Patients With Moderate-to-Severe Asthma Uncontrolled on Medium-High Dose ICS-LABA

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-11-16
Completion: 2025-10-28
Conditions
Asthma
Interventions
DRUG OTHER
No Results Yet
NCT06015737 | RECRUITING | PHASE3
302 Participants

A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-06-29
Completion: 2026-11-15
Conditions
Cutaneous Lupus Erythematosus
Interventions
COMBINATION_PRODUCT OTHER
No Results Yet
NCT06008756 | ACTIVE_NOT_RECRUITING | PHASE3
14550 Participants

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-10-09
Completion: 2029-11-29
Conditions
Arteriosclerosis Hypercholesterolaemia
Interventions
DRUG
No Results Yet
NCT06006078 | COMPLETED | NA
57 Participants

Aerosolization During Upper Endoscopy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2021-08-31
Completion: 2021-10-15
Conditions
Infectious Gastro-Intestinal Disorder Safety Issues
Interventions
DEVICE
Results Available
NCT06004440 | RECRUITING
3000 Participants

Real World Registry for Use of the Ion Endoluminal System

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2023-09-21
Completion: 2029-08-31
Conditions
Lung Cancer Multiple Pulmonary Nodules Lung Neoplasms Respiratory Tract Neoplasms Thoracic Neoplasms Neoplasms by Site Neoplasms Lung Diseases Respiratory Tract Diseases
Interventions
DEVICE
No Results Yet
NCT06004232 | ACTIVE_NOT_RECRUITING | NA
62 Participants

Prenatal Yoga to Prevent Postpartum Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-02-26
Completion: 2026-03-31
Conditions
Postpartum Depression
Interventions
BEHAVIORAL
No Results Yet
NCT06002828 | RECRUITING
2000 Participants

Evaluating the Impact of Social and Genetic Factors on Outcomes in Adolescent and Young Adult Cancer Survivors

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2023-10-13
Completion: 2030-02-01
Conditions
Hodgkin Lymphoma Non-Hodgkin Lymphoma
Interventions
PROCEDURE OTHER
No Results Yet
NCT05997017 | RECRUITING | PHASE2
29 Participants

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-12-28
Completion: 2026-12-31
Conditions
Endometrial Cancer Endometrioid Tumor Cancer Tumor Recurrent Endometrial Carcinoma Endometrioid Endometrial Cancer
Interventions
DRUG
No Results Yet
NCT05993611 | SUSPENDED | PHASE1
27 Participants

Allogeneic CD6 Chimeric Antigen Receptor T Regulatory Cells (CD6-CAR Tregs) for the Treatment of Patients With Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-02-19
Completion: 2028-05-21
Conditions
Chronic Graft Versus Host Disease Hematologic and Lymphocytic Disorder Steroid Refractory Graft Versus Host Disease
Interventions
PROCEDURE BIOLOGICAL OTHER
No Results Yet
NCT05972551 | RECRUITING | PHASE3
106 Participants

Study to Evaluate Efficacy and Safety of Romosozumab Compared With Bisphosphonates in Children and Adolescents With Osteogenesis Imperfecta

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-04-22
Completion: 2027-06-01
Conditions
Osteogenesis Imperfecta
Interventions
DRUG
No Results Yet
NCT05968742 | RECRUITING | NA
80 Participants

Variation in Gingival Inflammatory Responses

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-06-30
Completion: 2026-10-01
Conditions
Gingivitis
Interventions
BEHAVIORAL
No Results Yet
NCT05966805 | COMPLETED | NA
21 Participants

Impact of Exercise Intervention on Well-being in Shift-working Acute Care Nurses

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-09-13
Completion: 2025-05-13
Conditions
Psychological Wellness
Interventions
BEHAVIORAL
No Results Yet
NCT05954871 | COMPLETED | PHASE1
10 Participants

Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-01-08
Completion: 2025-09-16
Conditions
Colorectal Cancer Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT05949177 | RECRUITING | NA
50 Participants

Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-10-30
Completion: 2026-07-31
Conditions
Anterior Cruciate Ligament Injuries
Interventions
BEHAVIORAL
No Results Yet
NCT05936580 | RECRUITING | PHASE4
28 Participants

Nuwiq Dosing and Outcomes In the ManagEment of Women/Girls With Haemophilia A Needing FVIII Treatment for Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2025-12-31
Completion: 2027-02-28
Conditions
Hemophilia A
Interventions
DRUG
No Results Yet
NCT05933174 | RECRUITING | NA
220 Participants

Promoting Alternatives to Sulfonylureas to Improve Patient Safety in Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-10-01
Completion: 2026-06-30
Conditions
Type2diabetes
Interventions
OTHER
No Results Yet
NCT05931497 | RECRUITING | NA
21 Participants

Sauna for Long Covid

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2026-08-01
Completion: 2026-09-30
Conditions
Long COVID
Interventions
DEVICE
No Results Yet
NCT05920356 | RECRUITING | PHASE3
750 Participants

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-11-16
Completion: 2026-06-30
Conditions
Non-Small Cell Lung Cancer (NSCLC)
Interventions
DRUG
No Results Yet
NCT05912231 | ACTIVE_NOT_RECRUITING | NA
60 Participants

Ultrahypofractionation and Normal Tissue Toxicity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-08-15
Completion: 2026-12-31
Conditions
Breast Cancer Breast Cancer Female Breast Cancer Stage II Breast Cancer Stage III Myocardial Fibrosis
Interventions
RADIATION
No Results Yet
NCT05909761 | RECRUITING
60 Participants

Observational Safety Study in Women With Neuromyelitis Optica Spectrum Disorder (NMOSD) Exposed to UPLIZNA® During Pregnancy

Study Type: OBSERVATIONAL
Last Updated: 2025-11-13
Start Date: 2026-01-15
Completion: 2032-10-31
Conditions
Neuromyelitis Optica Spectrum Disorder Pregnancy Related
Interventions
DRUG
No Results Yet
NCT05907122 | COMPLETED | PHASE3
256 Participants

A Study to Evaluate Similarity of ABP 206 Compared With OPDIVO® (Nivolumab) in Subjects With Resected Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-07-26
Completion: 2025-10-31
Conditions
Melanoma
Interventions
DRUG
No Results Yet
NCT05904886 | ACTIVE_NOT_RECRUITING | PHASE3
687 Participants

A Study Evaluating Atezolizumab and Bevacizumab, With or Without Tiragolumab, in Participants With Untreated Locally Advanced or Metastatic Hepatocellular Carcinoma (HCC) (IMbrave152)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-09-14
Completion: 2025-05-08
Conditions
Hepatocellular Carcinoma
Interventions
DRUG OTHER
No Results Yet
NCT05896254 | COMPLETED | PHASE1/PHASE2
55 Participants

Study of MAR001 in Adults With Metabolic Dysfunction

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-07-22
Completion: 2024-12-13
Conditions
Hypertriglyceridemia
Interventions
DRUG
No Results Yet
NCT05888441 | RECRUITING | NA
200 Participants

Obstacle Negotiation in Older People With and Without Vision Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-04-14
Completion: 2028-12-31
Conditions
Low Vision
Interventions
OTHER
No Results Yet
NCT05864846 | ACTIVE_NOT_RECRUITING | PHASE4
79 Participants

A Study to Investigate Behavioral and Other Co-Occurring Outcomes With Epidiolex as Add-On Therapy in Participants Aged 1 to 65 Years of Age With Tuberous Sclerosis Complex

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-06-29
Completion: 2026-03-26
Conditions
Tuberous Sclerosis Complex Associated Neuropsychiatric Disease
Interventions
DRUG
No Results Yet
NCT05863351 | RECRUITING | PHASE3
472 Participants

Focused Radiation Versus Systemic Therapy for Kidney Cancer Patients With Limited Metastasis, SOAR Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-09-07
Completion: 2030-12-01
Conditions
Metastatic Renal Cell Carcinoma Stage IV Renal Cell Cancer AJCC v8
Interventions
PROCEDURE OTHER
No Results Yet
NCT05863195 | RECRUITING | PHASE3
408 Participants

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-10-19
Completion: 2029-06-30
Conditions
Metastatic Colorectal Carcinoma Metastatic Malignant Neoplasm in the Liver Stage IV Colorectal Cancer AJCC v8 Unresectable Colorectal Carcinoma
Interventions
BIOLOGICAL PROCEDURE DRUG
No Results Yet
NCT05862727 | ACTIVE_NOT_RECRUITING | NA
46 Participants

Preschool Attention and Sleep Support (PASS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-07-24
Completion: 2026-01-31
Conditions
ADHD Psychiatric Health
Interventions
BEHAVIORAL
No Results Yet
NCT05839067 | RECRUITING | NA
100 Participants

Supporting Health in Veterans With Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-05-31
Completion: 2026-09-30
Conditions
Heart Failure
Interventions
BEHAVIORAL
No Results Yet
NCT05827081 | RECRUITING | PHASE3
1400 Participants

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2024-02-28
Completion: 2029-09-07
Conditions
Early Breast Cancer
Interventions
DRUG
No Results Yet
NCT05820477 | ACTIVE_NOT_RECRUITING | NA
280 Participants

FAMS-T1D Self-Regulation and Social Support for T1D

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-04-25
Completion: 2027-01-31
Conditions
Type 1 Diabetes
Interventions
BEHAVIORAL
No Results Yet
NCT05815160 | ACTIVE_NOT_RECRUITING | PHASE1
34 Participants

Debio 0123 in Combination With Carboplatin and Etoposide in Adult Participants With Small Cell Lung Cancer That Recurred or Progressed After Previous Standard Platinum-Based Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-05-02
Completion: 2026-01-31
Conditions
Small Cell Lung Cancer Recurrent
Interventions
DRUG
No Results Yet
NCT05805501 | ACTIVE_NOT_RECRUITING | PHASE2
199 Participants

A Study of Immune Checkpoint Inhibitor Combinations With Axitinib in Participants With Untreated Locally Advanced Unresectable or Metastatic Renal Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-04-21
Completion: 2026-07-31
Conditions
Renal Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT05804318 | RECRUITING | NA
132 Participants

Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-13
Start Date: 2023-04-13
Completion: 2026-07-31
Conditions
Prostate Cancer
Interventions
DEVICE
No Results Yet
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