Clinical Trials

Showing trials with last updates posted in 2025.

NCT07009886 | RECRUITING | NA
155 Participants

Development of an Educational Patient Decision Aid (Treatments in Advanced Cancer - Decision Aid, TA-DA) to Promote Shared Decision Making for Third-line or Beyond Palliative Systemic Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-10
Completion: 2028-07-31
Conditions
Advanced Cancer
Interventions
OTHER
No Results Yet
NCT07008963 | RECRUITING
50 Participants

Interview of Patients With HR+/HER2- Metastatic Breast Cancer Who Received Capivasertib + Fulvestrant

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-31
Completion: 2025-12-31
Conditions
Metastatic Breast Cancer
Interventions
OTHER
No Results Yet
NCT06996639 | RECRUITING | NA
400 Participants

Breaking Fasts Ahead of Cardiac Caths

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-13
Completion: 2026-06-30
Conditions
Stable Angina (SA) Unstable Angina (UA) NSTEMI - Non-ST Segment Elevation MI
Interventions
BEHAVIORAL
No Results Yet
NCT06995651 | RECRUITING | PHASE1
15 Participants

Dorzagliatin in Pancreatic Insufficient Cystic Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2027-07-31
Conditions
Pancreatic Insufficiency Cystic Fibrosis-related Diabetes
Interventions
DRUG
No Results Yet
NCT06991556 | RECRUITING | PHASE2
150 Participants

An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-07
Completion: 2032-04-19
Conditions
Metastatic Hormone-sensitive Prostate Cancer
Interventions
DRUG
No Results Yet
NCT06989437 | RECRUITING | PHASE2/PHASE3
982 Participants

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-03
Completion: 2028-01-30
Conditions
Cachexia Metastatic Pancreatic Ductal Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT06987318 | NOT_YET_RECRUITING | PHASE1
40 Participants

A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-02-15
Completion: 2027-08-29
Conditions
HIV-1-infection
Interventions
BIOLOGICAL
No Results Yet
NCT06979453 | RECRUITING | PHASE3
366 Participants

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-15
Completion: 2029-10-12
Conditions
Plaque Psoriasis
Interventions
DRUG OTHER
No Results Yet
NCT06977503 | NOT_YET_RECRUITING | NA
40 Participants

Alpha-Stim AIDยฎ Together With Life Coaching for the Support of Burnout Symptoms in Healthcare Workers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2026-12-15
Conditions
Psychiatric Disorder
Interventions
PROCEDURE OTHER BEHAVIORAL
No Results Yet
NCT06976476 | RECRUITING | PHASE2
100 Participants

Study of IgPro20 to Prevent Infection in People With Multiple Myeloma and Hypogammaglobulinemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-08
Completion: 2029-05-08
Conditions
Multiple Myeloma Hypogammaglobulinemia Hypogammaglobulinemia, Acquired
Interventions
DRUG
No Results Yet
NCT06976216 | RECRUITING | PHASE3
586 Participants

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-14
Completion: 2028-09-11
Conditions
Alzheimer's Disease
Interventions
DRUG OTHER
No Results Yet
NCT06976203 | RECRUITING | PHASE3
586 Participants

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-21
Completion: 2028-09-11
Conditions
Alzheimer's Disease
Interventions
DRUG OTHER
No Results Yet
NCT06975046 | NOT_YET_RECRUITING | NA
365 Participants

Aerodynamic Measurements in the Pediatric Population

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2030-12-31
Conditions
Normal Voice
Interventions
DEVICE
No Results Yet
NCT06973564 | RECRUITING | PHASE1/PHASE2
294 Participants

JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-29
Completion: 2027-11-30
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06972381 | RECRUITING | NA
68 Participants

Piloting a Patient Navigator Program for Weight Loss

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-15
Completion: 2027-02-15
Conditions
Obesity Overweight
Interventions
BEHAVIORAL
No Results Yet
NCT06966479 | RECRUITING | PHASE2
436 Participants

A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-21
Completion: 2027-09-30
Conditions
Severe Asthma
Interventions
DRUG
No Results Yet
NCT06965413 | ACTIVE_NOT_RECRUITING | PHASE2
285 Participants

A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-05
Completion: 2026-08-21
Conditions
Obesity Overweight Overweight With One Weight Related Comorbidity
Interventions
DRUG
No Results Yet
NCT06963827 | RECRUITING | PHASE3
347 Participants

A Study of Mezagitamab in Adults With Primary IgA Nephropathy Kidney Condition

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-15
Completion: 2028-09-07
Conditions
Kidney Disease
Interventions
DRUG
No Results Yet
NCT06961357 | RECRUITING | PHASE1/PHASE2
36 Participants

Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2029-05-31
Conditions
Melanoma
Interventions
DRUG
No Results Yet
NCT06954792 | ENROLLING_BY_INVITATION
140 Participants

Biventricular Remodeling in Transcatheter Tricuspid Valve Replacement - Acute Hemodynamic Instability Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-31
Completion: 2026-05-01
Conditions
Tricuspid Regurgitation Heart Failure Structural Heart Disease Interventional Cardiology
No Results Yet
NCT06933329 | RECRUITING | PHASE2
73 Participants

Zelenectide Pevedotin in NECTIN4 Amplified Advanced or Metastatic Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-18
Completion: 2028-08-31
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06931626 | RECRUITING | PHASE1
10 Participants

Study of NMS-03305293 in Adult Patient With Relapsed Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-15
Completion: 2026-10-30
Conditions
Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06930755 | RECRUITING | PHASE1
24 Participants

Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-31
Completion: 2027-05-31
Conditions
Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT06929273 | RECRUITING | PHASE3
450 Participants

A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-18
Completion: 2028-06-13
Conditions
Bipolar Disorder Type I With Mania
Interventions
DRUG
No Results Yet
NCT06926660 | RECRUITING | PHASE2
416 Participants

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Chronic Kidney Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-07-18
Completion: 2027-01-08
Conditions
Chronic Kidney Disease
Interventions
DRUG
No Results Yet
NCT06921837 | RECRUITING | PHASE1/PHASE2
122 Participants

A First-in-Human Study Using BDC-4182 as a Single Agent in Advanced Gastric and Gastroesophageal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-26
Completion: 2027-05-31
Conditions
Gastric Cancer Adenocarcinoma Metastatic Gastroesophageal Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT06918067 | RECRUITING | NA
17 Participants

Comparison of Urinary Flow Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-06
Completion: 2026-12-31
Conditions
Urinary Retention
Interventions
DEVICE
No Results Yet
NCT06916221 | RECRUITING | NA
150 Participants

BID LTM Digital Intervention in Aging

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-08-20
Completion: 2027-12-31
Conditions
Long-Term Memory Inhibitory Control
Interventions
BEHAVIORAL
No Results Yet
NCT06911931 | RECRUITING | NA
84 Participants

Visual Perception in Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-11-03
Completion: 2027-01-31
Conditions
Schizophrenia Disorders Bipolar Disorder Schizo Affective Disorder
Interventions
OTHER
No Results Yet
NCT06906809 | COMPLETED | PHASE1
37 Participants

Effect of Phenytoin or Itraconazole on How BGB-16673 is Absorbed and Removed From the Body in Healthy Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-03
Completion: 2025-10-13
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT06906640 | RECRUITING | NA
1170 Participants

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (IRIS-CKD) (Program 2)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-28
Completion: 2027-04-01
Conditions
Chronic Kidney Disease(CKD) Type 2 DM Type 2 Diabetes Mellitus (T2DM)
Interventions
OTHER
No Results Yet
NCT06906627 | RECRUITING | NA
800 Participants

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-10-28
Completion: 2027-04-01
Conditions
Chronic Kidney Disease(CKD) Type 2 DM Type 2 Diabetes Mellitus (T2DM)
Interventions
OTHER
No Results Yet
NCT06900595 | RECRUITING | PHASE2
48 Participants

Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-07-19
Completion: 2029-06-02
Conditions
Locally Advanced Adrenal Cortical Carcinoma Metastatic Adrenal Cortical Carcinoma Recurrent Adrenal Cortical Carcinoma Stage III Adrenal Cortical Carcinoma AJCC v8 Stage IV Adrenal Cortical Carcinoma AJCC v8 Unresectable Adrenal Cortical Carcinoma
Interventions
PROCEDURE DRUG BIOLOGICAL
No Results Yet
NCT06894511 | RECRUITING | PHASE2
420 Participants

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI Versus AAA617 in PSMA Positive First-line mCRPC

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-09-11
Completion: 2029-04-09
Conditions
Metastatic Castration Resistant Prostate Cancer (mCRPC)
Interventions
DRUG
No Results Yet
NCT06892548 | RECRUITING | PHASE1/PHASE2
594 Participants

A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-02
Completion: 2027-08-31
Conditions
Advanced Lung Cancer
Interventions
BIOLOGICAL
No Results Yet
NCT06890884 | RECRUITING | PHASE2
594 Participants

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-11
Completion: 2027-12-13
Conditions
Lymphoma, Large B-Cell, Diffuse
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06887972 | ACTIVE_NOT_RECRUITING | PHASE4
100 Participants

A Single-Arm Study Evaluating the Effectiveness and Safety of Suzetrigine (SUZ) for Acute Pain After Aesthetic or Reconstructive Surgeries

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-03-21
Completion: 2025-10-24
Conditions
Acute Pain
Interventions
DRUG
No Results Yet
NCT06884449 | COMPLETED | NA
135 Participants

A Placebo-Controlled Study Evaluating the Effects of Arrabina P on Satiety in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-15
Completion: 2025-10-28
Conditions
Satiety Appetite Regulation Weight Control
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT06882785 | RECRUITING | PHASE3
250 Participants

A Study to Evaluate the Efficacy and Safety of KarXT in Acutely Psychotic Japanese Adult Participants With Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-06-10
Completion: 2028-09-23
Conditions
Schizophrenia
Interventions
DRUG OTHER
No Results Yet
NCT06881784 | RECRUITING | PHASE3
420 Participants

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-05-06
Completion: 2027-12-01
Conditions
NSCLC (Non-small Cell Lung Cancer) Non-Small Cell Lung Cancer NSCLC NSCLC (Non-small Cell Lung Carcinoma) NSCLC (Advanced Non-small Cell Lung Cancer)
Interventions
DRUG
No Results Yet
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