Clinical Trials
500
Participants
Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-03-03
Completion:
2028-03-31
Conditions
Major Depressive Disorder (MDD)
Interventions
DRUG
No Results Yet
26
Participants
Automated Inhaler Monitoring for Asthma Medication Usage
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-31
Completion:
2026-03-31
Conditions
Asthma
Interventions
DEVICE
No Results Yet
130
Participants
A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-02-11
Completion:
2028-11-30
Conditions
Primary Open Angle Glaucoma
Interventions
DEVICE
No Results Yet
437
Participants
Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2026-07-17
Completion:
2032-07-15
Conditions
CIC-Rearranged Sarcoma
Metastatic Ewing Sarcoma
Metastatic High Grade Sarcoma
Metastatic Undifferentiated Round Cell Sarcoma
Metastatic Undifferentiated Sarcoma, Not Otherwise Specified
Round Cell Sarcoma With EWSR1-non-ETS Fusion
Sarcoma With BCOR Genetic Alterations
Interventions
PROCEDURE
DRUG
OTHER
RADIATION
No Results Yet
425
Participants
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-12
Completion:
2028-12-31
Conditions
Moderately to Severely Active Crohns Disease
Interventions
DRUG
No Results Yet
600
Participants
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-03-17
Completion:
2028-12-31
Conditions
Moderately to Severely Active Crohns Disease
Interventions
DRUG
No Results Yet
200
Participants
A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal Antibodies Given Intravenously in Adult Participants Without HIV
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-03-07
Completion:
2027-01-15
Conditions
HIV
Interventions
BIOLOGICAL
No Results Yet
854
Participants
iCanQuit Smoking Cessation Among Hispanic Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2026-01-01
Completion:
2029-07-01
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
DEVICE
DRUG
OTHER
No Results Yet
198
Participants
A Study of BBT001 in Healthy Volunteers (HVs) and in Adult Patients With Atopic Dermatitis (AD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-02-27
Completion:
2026-08-21
Conditions
Atopic Dermatitis
Interventions
DRUG
No Results Yet
400
Participants
A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-13
Completion:
2027-07-17
Conditions
Interstitial Lung Diseases
Systemic Autoimmune Rheumatic Diseases Associated Interstitial Lung Diseases
Interventions
DRUG
No Results Yet
50
Participants
Urine Methylation Markers in UTUC
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-07
Completion:
2026-06-30
Conditions
Upper Tract Urothelial Cancer
Interventions
DIAGNOSTIC_TEST
No Results Yet
124
Participants
A Study to Measure the Effects of Using Tradipitant on Nausea and Vomiting After GLP-1R Agonist Use
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-02-25
Completion:
2025-10-06
Conditions
Obesity
Interventions
DRUG
No Results Yet
240
Participants
Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients With Grade 1 and Grade 2 Advanced GEP-NET
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-30
Completion:
2030-09-27
Conditions
Somatostatin Receptor Positive (SSTR+)
Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET)
Interventions
RADIATION
DRUG
No Results Yet
200
Participants
A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-06-05
Completion:
2026-11-18
Conditions
Multiple Sclerosis Spasticity
Interventions
DRUG
No Results Yet
432
Participants
Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-02-27
Completion:
2028-06-27
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
520
Participants
Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-24
Completion:
2027-05-31
Conditions
Respiratory Distress Syndrome
Pre-term Infants
Interventions
COMBINATION_PRODUCT
OTHER
No Results Yet
61
Participants
Acalabrutinib for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-27
Completion:
2026-12-31
Conditions
Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Interventions
DRUG
PROCEDURE
No Results Yet
30
Participants
Pilot Testing a Novel Approach to Pediatric Obesity Treatment
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-01
Completion:
2025-12-31
Conditions
Overweight Adolescents
Obese Adolescents
Interventions
BEHAVIORAL
OTHER
No Results Yet
40
Participants
Belumosudil for Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-09-11
Completion:
2027-12-31
Conditions
Rejection Chronic Renal
Interventions
DRUG
No Results Yet
55
Participants
BZLF1 Peptide Vaccine (OSU-2131) With QS-21 for the Prevention of Epstein-Barr Virus Related Cancer in Patients Awaiting Solid Organ Transplants
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-12-01
Completion:
2026-12-31
Conditions
Chronic Kidney Disease, Stage 4
Chronic Kidney Disease, Stage 5
EBV-Related Lymphoproliferative Disorder
EBV-Related Malignant Neoplasm
Post-Transplant Lymphoproliferative Disorder
Interventions
PROCEDURE
DRUG
BIOLOGICAL
No Results Yet
30
Participants
Humanity Neurotech Device Clinical Trial in Adults With Long COVID Cognitive Dysfunction
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-12-19
Completion:
2025-12-31
Conditions
Post-Acute COVID-19 Syndrome
Cognitive Dysfunction
Interventions
DEVICE
No Results Yet
15
Participants
Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-06-09
Completion:
2029-03-07
Conditions
Acute Lymphoblastic Leukemia
Interventions
PROCEDURE
BIOLOGICAL
OTHER
No Results Yet
48
Participants
Subthreshold Vestibular Stimulation as a Strategy for Rehabilitation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2026-01-01
Completion:
2026-12-31
Conditions
Vestibular Hypofunction
Bilateral Vestibular Hypofunction
Presbyvestibulopathy
Healthy Controls
Interventions
BEHAVIORAL
OTHER
No Results Yet
60
Participants
A Study of Lorigerlimab in Participants With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-01
Completion:
2027-02-28
Conditions
Platinum-resistant Ovarian Cancer
Platinum-Resistant Fallopian Tube Carcinoma
Platinum-Resistant Primary Peritoneal Carcinoma
Clear Cell Adenocarcinoma of Ovary
Clear Cell Adenocarcinoma of Vulva
Clear Cell Adenocarcinoma of Vagina
Clear Cell Adenocarcinoma of Cervix
Clear Cell Adenocarcinoma of Uterus
Clear Cell Adenocarcinoma of Fallopian Tube
Clear Cell Adenocarcinoma of Peritoneum
Endometrial Cancer
Interventions
BIOLOGICAL
No Results Yet
129
Participants
The Role of Cerebral NIRS in Preventing Brain Injury of Very Low Birth Weight Preterm Infants
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2017-05-01
Completion:
2020-05-01
Conditions
Neonatal Cerebral Leukomalacia
Intracranial Nontraumatic Haemorrhage of Fetus and Newborn
Neonatal Mortality
Interventions
DEVICE
OTHER
No Results Yet
144
Participants
PS230005 Control-IQ 1.5 Post-Approval Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2025-01-30
Completion:
2026-08-11
Conditions
Type 1 Diabetes
Interventions
DEVICE
No Results Yet
1046
Participants
A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-01-27
Completion:
2029-07-02
Conditions
Diffuse Large B-Cell Lymphoma
Interventions
BIOLOGICAL
DRUG
No Results Yet
640
Participants
A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-07-11
Completion:
2029-10-01
Conditions
Oncology
Myeloid Leukemia, Acute
Cancer
Interventions
BEHAVIORAL
No Results Yet
740
Participants
Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-22
Completion:
2035-12-31
Conditions
Advanced Melanoma
Interventions
DRUG
No Results Yet
200
Participants
STOP-UC: De-escalation of Therapy in Patients With Ulcerative Colitis With Histological Remission
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-11-30
Completion:
2026-11-30
Conditions
Ulcerative Colitis (UC)
Interventions
OTHER
No Results Yet
60
Participants
The RECAP2 Study: Midazolam and Psilocybin
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-08-07
Completion:
2027-12-31
Conditions
Psilocybin
Interventions
DRUG
No Results Yet
60
Participants
A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti--IL-33 mAb) in Participants With Chronic Rhinosinusitis Without Nasal Polyps
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-12-16
Completion:
2026-08-07
Conditions
Chronic Rhinosinusitis Without Nasal Polyps
Interventions
DRUG
No Results Yet
214
Participants
A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-12-16
Completion:
2026-05-22
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
120
Participants
A Trial of Felzartamab in Kidney Transplant Recipients With Late Antibody-Mediated Rejection (AMR)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-12-03
Completion:
2026-12-01
Conditions
Antibody-mediated Rejection
Interventions
DRUG
No Results Yet
93
Participants
A Study Investigating BG-60366 in Adults With Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-11-26
Completion:
2028-04-30
Conditions
Non-Small Cell Lung Cancer
Lung Cancer
NSCLC
NSCLC (Non-small Cell Lung Carcinoma)
EGFR Activating Mutation
EGFR Mutation-Related Tumors
Interventions
DRUG
No Results Yet
110
Participants
A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-05-28
Completion:
2028-03-31
Conditions
Advanced High-Grade Epithelial Ovarian
Primary Peritoneal
Fallopian Tube Cancers
High Folate Receptor-Alpha Expression
Platinum Resistant
Interventions
DRUG
No Results Yet
150
Participants
A Phase 2 Study of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-01-17
Completion:
2026-09-30
Conditions
Parkinson Disease
Parkinson
Idiopathic Parkinson Disease
Early Parkinson Disease (Early PD)
Parkinson Disease, Idiopathic
Interventions
DRUG
OTHER
No Results Yet
30
Participants
Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living With HIV-1 on Suppressive Antiretroviral Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2025-04-01
Completion:
2027-04-30
Conditions
HIV-1
Interventions
BIOLOGICAL
OTHER
No Results Yet
2330
Participants
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-12-08
Completion:
2026-12-06
Conditions
COVID-19 SARS-CoV-2 Infection
Interventions
DRUG
No Results Yet
50
Participants
Development of a Novel Endoscopic Index and Patient-reported Outcome Measure for Clinical Trials in Participants With Permanent Ileostomy
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2024-06-19
Completion:
2026-06-30
Conditions
Crohns Disease
No Results Yet
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