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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06422884 | RECRUITING | PHASE2
200 Participants

A Phase 2 Trial of ENV-101 in Patients With Lung Fibrosis (WHISTLE-PF Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-15
Completion: 2026-10-31
Conditions
Idiopathic Pulmonary Fibrosis Progressive Fibrosing Interstitial Lung Disease
Interventions
DRUG
No Results Yet
NCT06422806 | RECRUITING | PHASE3
365 Participants

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-11
Completion: 2026-06-30
Conditions
Metastatic Dedifferentiated Liposarcoma Metastatic Undifferentiated Pleomorphic Sarcoma Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 Unresectable Dedifferentiated Liposarcoma Unresectable Undifferentiated Pleomorphic Sarcoma
Interventions
PROCEDURE DRUG BIOLOGICAL
No Results Yet
NCT06421636 | RECRUITING | PHASE2
95 Participants

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-30
Completion: 2028-01-24
Conditions
Non-Transfusion Dependent Beta-Thalassemia (NTDT)
Interventions
DRUG
No Results Yet
NCT06418711 | TERMINATED | PHASE3
132 Participants

ICoN-1 Phase 3 Study of the Efficacy and Safety of Treatment With MNKD-101, Clofazimine Inhalation Suspension

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-11
Completion: 2025-11-10
Conditions
MAC Lung Disease Treatment Refractory MAC Lung Disease Mycobacterium Infections, Nontuberculous
Interventions
DRUG
No Results Yet
NCT06417775 | RECRUITING | PHASE3
496 Participants

Study of Oral Ubrogepant to Assess Adverse Events and Change in Disease Activity in Adult Participants With Menstrual Migraine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-10
Completion: 2027-06-30
Conditions
Migraine
Interventions
DRUG
No Results Yet
NCT06413498 | RECRUITING | PHASE3
450 Participants

A Study Comparing Anitocabtagene Autoleucel to Standard of Care Therapy in Participants With Relapsed/ Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-23
Completion: 2028-07-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06413173 | RECRUITING | NA
160 Participants

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-07-25
Completion: 2028-09-30
Conditions
Brain Concussion Brain Trauma Attention Concentration Difficulty Brain Injuries Brain Injuries, Traumatic Neurocognitive Dysfunction Attention Impaired Memory Impairment Mild Traumatic Brain Injury Mild Cognitive Impairment Post Concussive Symptoms
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT06412666 | RECRUITING | PHASE2/PHASE3
55 Participants

A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-05-29
Completion: 2030-01-31
Conditions
Pediatric Symptomatic Obstructive Hypertrophic Cardiomyopathy
Interventions
DRUG
No Results Yet
NCT06405347 | COMPLETED | NA
612 Participants

The M-Well Inpatient Whole Health Bundle

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-12
Completion: 2025-10-22
Conditions
Patient Satisfaction
Interventions
BEHAVIORAL
No Results Yet
NCT06395415 | RECRUITING | NA
46 Participants

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-25
Completion: 2026-02-28
Conditions
Electronic Nicotine Delivery Systems Tobacco Products Cigarette Smoking
Interventions
BEHAVIORAL
No Results Yet
NCT06386315 | RECRUITING | PHASE2
112 Participants

Reduced Dose Radiotherapy for the Treatment of Indolent Non-Hodgkin Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-05-15
Completion: 2026-05-30
Conditions
Indolent B-Cell Non-Hodgkin Lymphoma Recurrent Indolent B-Cell Non-Hodgkin Lymphoma Refractory Indolent B-Cell Non-Hodgkin Lymphoma Recurrent Indolent Non-Hodgkin Lymphoma Refractory Indolent Non-Hodgkin Lymphoma
Interventions
PROCEDURE RADIATION OTHER
No Results Yet
NCT06384573 | ACTIVE_NOT_RECRUITING | PHASE3
43 Participants

DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-10
Completion: 2030-06-30
Conditions
Alzheimer's Disease Dementia Alzheimer's Disease, Familial
Interventions
DRUG
No Results Yet
NCT06380322 | RECRUITING
650 Participants

Military Health and Nutrition Examination Study

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-24
Completion: 2026-12-01
Conditions
Hypertension Type 2 Diabetes Dyslipidemias Cardiovascular Diseases
No Results Yet
NCT06369285 | RECRUITING | PHASE2
150 Participants

A Study of Alisertib in Combination With Endocrine Therapy in Patients With HR-positive, HER2-negative Recurrent or Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-19
Completion: 2027-06-30
Conditions
Hormone Receptor Positive HER-2 Negative Breast Cancer Metastatic Breast Cancer Recurrent Breast Cancer
Interventions
DRUG
No Results Yet
NCT06366152 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated: 2025-11-12
No Results Yet
NCT06364514 | RECRUITING | NA
50 Participants

PICNIC Study - PatIent Centered aNtIbiotic Courses in Children With Medical Complexity

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-20
Completion: 2026-06-01
Conditions
Pneumonia
Interventions
OTHER
No Results Yet
NCT06364228 | RECRUITING | PHASE2
32 Participants

Intranasal Oxytocin Intervention for Caregivers to Persons With Dementia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-01-05
Completion: 2027-02-28
Conditions
Stress
Interventions
DRUG PROCEDURE
No Results Yet
NCT06356220 | RECRUITING | NA
120 Participants

GF-NOURISH (Gluten Free Nutrition Optimization Through Ultra-processed Food Reduction and Improved Strategies for Health)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-29
Completion: 2026-05-31
Conditions
Celiac Disease in Children Nutrition Disorder, Child
Interventions
OTHER
No Results Yet
NCT06353386 | RECRUITING | PHASE1/PHASE2
220 Participants

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-05-20
Completion: 2029-01-15
Conditions
Prostatic Neoplasms, Castration-Resistant
Interventions
DRUG
No Results Yet
NCT06351644 | TERMINATED | PHASE1/PHASE2
2 Participants

ON 123300 (Narazaciclib) and Dexamethasone in Patients With Relapsed and/or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-10-02
Completion: 2025-04-28
Conditions
Relapsed and/or Refractory Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06342986 | RECRUITING | PHASE1
33 Participants

Intraperitoneal FT536 in Recurrent Ovarian, Fallopian Tube, and Primary Peritoneal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-07-11
Completion: 2026-12-31
Conditions
Gynecologic Cancer Ovarian Cancer Fallopian Tube Cancer Primary Peritoneal Cavity Cancer
Interventions
DRUG
No Results Yet
NCT06338748 | ACTIVE_NOT_RECRUITING | NA
28 Participants

Accuracy of the Dexcom G7 Continuous Glucose Monitoring System Following Cardiac Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-02
Completion: 2025-10-01
Conditions
Continuous Glucose Monitoring
Interventions
DEVICE
No Results Yet
NCT06335303 | ACTIVE_NOT_RECRUITING | PHASE2
322 Participants

A Study to Test Whether BI 1819479 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-05
Completion: 2025-11-14
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
DRUG
No Results Yet
NCT06333652 | RECRUITING | PHASE2
14 Participants

Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2026-03-01
Completion: 2026-12-31
Conditions
Preeclampsia
Interventions
DRUG
No Results Yet
NCT06325683 | RECRUITING | PHASE2
184 Participants

Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-11-08
Completion: 2028-07-15
Conditions
Progressive Glioblastoma Recurrent Glioblastoma
Interventions
PROCEDURE DRUG BIOLOGICAL
No Results Yet
NCT06324357 | RECRUITING | PHASE1/PHASE2
582 Participants

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-03
Completion: 2029-09-28
Conditions
Metastatic Breast Cancer Metastatic Gastric Adenocarcinoma Gastroesophageal Junction Adenocarcinoma Esophageal Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT06317662 | RECRUITING | PHASE2
153 Participants

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-06-05
Completion: 2028-12-31
Conditions
Acute Leukemia of Ambiguous Lineage B Acute Lymphoblastic Leukemia
Interventions
DRUG PROCEDURE BIOLOGICAL
No Results Yet
NCT06317649 | RECRUITING | PHASE2
147 Participants

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-27
Completion: 2025-10-31
Conditions
Acute Myeloid Leukemia
Interventions
DRUG PROCEDURE
No Results Yet
NCT06317285 | TERMINATED | PHASE2
158 Participants

A Study to Evaluate the Efficacy and Safety of GSK3915393 in Participants With Idiopathic Pulmonary Fibrosis (IPF)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-04-04
Completion: 2025-10-01
Conditions
Idiopathic Pulmonary Fibrosis
Interventions
DRUG
No Results Yet
NCT06287775 | RECRUITING | PHASE1/PHASE2
45 Participants

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-04-08
Completion: 2029-07-25
Conditions
Extensive Stage Lung Small Cell Carcinoma Stage IV Lung Cancer AJCC v8
Interventions
BIOLOGICAL PROCEDURE DRUG
No Results Yet
NCT06286033 | RECRUITING | PHASE1
112 Participants

Single and Multiple Ascending Dose Study and Food Effect Study for AG181

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-20
Completion: 2026-03-31
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT06283394 | ACTIVE_NOT_RECRUITING | NA
224 Participants

Penn Medicine Food Market Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-01
Completion: 2025-05-01
Conditions
Obesity Diabetes
Interventions
BEHAVIORAL
No Results Yet
NCT06257628 | WITHDRAWN
0 Participants

MACE CDS Software Master Enrollment Protocol

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-09-14
Completion: 2025-05-31
Conditions
Cardiac Events
Interventions
DEVICE
No Results Yet
NCT06254326 | ACTIVE_NOT_RECRUITING | PHASE1
12 Participants

ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-09-19
Completion: 2027-12-31
Conditions
Recurrent Oligodendroglioma Progressive Oligodendroglioma
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06246110 | RECRUITING | PHASE2
70 Participants

A Phase 2 Study of EIK1001 in Combo With Pembrolizumab and Chemotherapy in Patients With Stage 4 NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-06
Completion: 2026-12-31
Conditions
NSCLC
Interventions
DRUG
No Results Yet
NCT06227026 | RECRUITING | PHASE1
10 Participants

Pilot Study of Anti-CD19 Chimeric Antigen Receptor T Cells (CAR-T Cells) for the Treatment of Relapsed/Refractory CD19+ Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-20
Completion: 2026-01-15
Conditions
Acute Lymphoblastic Leukemia Diffuse Large B Cell Lymphoma
Interventions
BIOLOGICAL
No Results Yet
NCT06226805 | RECRUITING | PHASE2
156 Participants

Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-07-31
Completion: 2027-06-30
Conditions
Acute Ischemic Stroke
Interventions
DRUG
No Results Yet
NCT06223555 | RECRUITING | NA
79 Participants

Variability In Mixed Meal Tests: Fixed Versus Adjusted to Energy Needs Caloric Dose

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-08-23
Completion: 2026-06-30
Conditions
Obesity Healthy Volunteer
Interventions
OTHER
No Results Yet
NCT06215118 | RECRUITING | PHASE1
87 Participants

A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-20
Completion: 2027-04-10
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06214741 | ACTIVE_NOT_RECRUITING | PHASE3
307 Participants

A Study to Test Whether Survodutide (BI 456906) Helps Chinese People Living With Overweight or Obesity to Lose Weight

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-06
Completion: 2025-07-29
Conditions
Obesity Overweight
Interventions
DRUG
No Results Yet
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