Clinical Trials
901
Participants
Open Label, Long-term Study Evaluating Safety and Efficacy of Subcutaneous Amlitelimab in Participants Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-04-03
Completion:
2031-06-11
Conditions
Dermatitis Atopic
Interventions
DRUG
No Results Yet
272
Participants
Pivotal Evaluation of Abdominal Neuromuscular Electrical Stimulation (VentFree) for Weaning From Mechanical Ventilation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-02-15
Completion:
2025-12-31
Conditions
Respiration, Artificial
Ventilators, Mechanical
Interventions
DEVICE
No Results Yet
50
Participants
An Open-Label Exploratory Study of Fosigotifator in Participants With Vanishing White Matter Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-03-13
Completion:
2027-11-30
Conditions
Vanishing White Matter Disease
Interventions
DRUG
No Results Yet
60
Participants
Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-05-01
Completion:
2027-11-30
Conditions
Primary Progressive Aphasia
Dementia
Dementia, Frontotemporal
Alzheimer Disease
Neurodegenerative Diseases
Frontotemporal Lobar Degeneration
Apraxia, Motor
Dysarthria
Communication Disorders
Language Disorders
Speech Disorders
Neurocognitive Disorders
Aphasia
Bilingual Aphasia
Interventions
BEHAVIORAL
No Results Yet
75
Participants
An Extension Study to a Clinical Study That Will Continue to Evaluate the Effectiveness and Safety of SEP-363856 in People With Schizophrenia That Switch to SEP-363856 From Their From Their Current Antipsychotic Medication
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-03-31
Completion:
2024-09-23
Conditions
Schizophrenia
Interventions
DRUG
500
Participants
Natural History of Inflammatory Muscle Diseases
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2023-06-01
Completion:
2032-02-25
Conditions
Inflammation In Skeletal Muscle
No Results Yet
1200
Participants
A Prospective Natural History Study of Lymphatic Anomalies
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2023-03-20
Completion:
2026-12-31
Conditions
Lymphatic Diseases
Lymphatic Abnormalities
No Results Yet
48
Participants
A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-08-19
Completion:
2028-04-06
Conditions
Acute HIV Infection
Interventions
BIOLOGICAL
OTHER
DRUG
No Results Yet
250
Participants
Nicotinamide and Pyruvate for Open Angle Glaucoma: A Randomized Clinical Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-03-14
Completion:
2026-06-30
Conditions
Primary Open Angle Glaucoma
Interventions
DRUG
No Results Yet
1122
Participants
A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-03-03
Completion:
2030-03-20
Conditions
High Grade Osteosarcoma
Localized Osteosarcoma
Metastatic Osteosarcoma
Secondary Osteosarcoma
Interventions
PROCEDURE
DRUG
No Results Yet
12327
Participants
A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-01-26
Completion:
2025-10-23
Conditions
Prevention of Ischemic Stroke
Acute Non-cardioembolic Ischemic Stroke
High-risk Transient Ischemic Attack
Interventions
DRUG
No Results Yet
28
Participants
Botensilimab, Balstilimab and Regorafenib for the Treatment of Patients With Microsatellite Stable Metastatic Colorectal Cancer Who Have Progressed on Prior Chemotherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-05-11
Completion:
2025-05-10
Conditions
Advanced Colorectal Adenocarcinoma
Advanced Microsatellite Stable Colorectal Carcinoma
Metastatic Colorectal Adenocarcinoma
Metastatic Microsatellite Stable Colorectal Carcinoma
Stage III Colorectal Cancer AJCC v8
Stage IV Colorectal Cancer AJCC v8
Interventions
BIOLOGICAL
PROCEDURE
DRUG
No Results Yet
68
Participants
Premedication to Reduce Amivantamab Associated Infusion Related Reactions
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-05-18
Completion:
2024-03-29
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
90
Participants
A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-12-30
Completion:
2026-03-02
Conditions
Warm Autoimmune Hemolytic Anemia (wAIHA)
Interventions
BIOLOGICAL
DRUG
No Results Yet
256
Participants
Vamikibart in Participants With Uveitic Macular Edema
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-03-23
Completion:
2025-05-07
Conditions
Uveitic Macular Edema
Interventions
DRUG
OTHER
No Results Yet
111
Participants
Observational Study Evaluating the Efficacy and Safety of Zanubrutinib in Participants With Waldenstrรถm Macroglobulinemia
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2023-03-03
Completion:
2026-12-31
Conditions
Waldenstrom Macroglobulinemia
Interventions
DRUG
No Results Yet
50
Participants
A Multi-Institution Study of TGFฮฒ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-11-14
Completion:
2026-12-01
Conditions
Pediatric Sarcoma, Refractory
Pediatric Sarcoma, Relapsed
Interventions
BIOLOGICAL
No Results Yet
593
Participants
Study of Novel Treatment Combinations in Patients With Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-03-16
Completion:
2029-09-30
Conditions
Lung Cancer
Advanced or Metastatic Non-Small-Cell Lung Cancer
Resectable Non-Small-Cell Lung Cancer
Interventions
DRUG
No Results Yet
101
Participants
A Clinical Study That Will Evaluate How Well SEP-363856 Works and How Safe it is in People With Schizophrenia That Switch to SEP-363856 From Their Current Antipsychotic Medication
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-12-19
Completion:
2024-04-01
Conditions
Schizophrenia
Interventions
DRUG
966
Participants
A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135), Daratumumab, Lenalidomide or Elranatamab and Lenalidomide Compared With Daratumumab, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-11-10
Completion:
2028-03-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
614
Participants
Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) โฅ50% (MK-3475-D46)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-02-06
Completion:
2027-01-12
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
BIOLOGICAL
No Results Yet
182
Participants
Dose-finding Study of SAR443122 in Adult Participants With Ulcerative Colitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-11-25
Completion:
2026-02-25
Conditions
Colitis Ulcerative
Interventions
DRUG
No Results Yet
45155
Participants
Suicide Prevention for Justice Involved Managed Care Subscribers
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-09-01
Completion:
2024-09-03
Conditions
Suicide and Self-harm
Interventions
BEHAVIORAL
15
Participants
Withdrawal of Tiratricol Treatment in Males With Monocarboxylate Transporter 8 Deficiency (MCT8 Deficiency)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-07-21
Completion:
2025-09-03
Conditions
Monocarboxylate Transporter 8 Deficiency
Allan-Herndon-Dudley Syndrome
Interventions
DRUG
No Results Yet
84
Participants
A Study of RP-3500 in Combination With Standard Radiation Therapy in People With Solid Tumor Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-09-30
Completion:
2026-09-30
Conditions
Solid Tumor
Metastatic Cancer
Interventions
DRUG
RADIATION
No Results Yet
34
Participants
Remote Cognitive Assessment for Surgical Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2022-06-29
Completion:
2024-02-29
Conditions
Mild Cognitive Impairment
Delirium
No Results Yet
214
Participants
A Study in People With Systemic Sclerosis to Test Whether Avenciguat (BI 685509) Has an Effect on Lung Function and Other Systemic Sclerosis Symptoms
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-12-13
Completion:
2025-10-22
Conditions
Scleroderma, Systemic
Interventions
DRUG
No Results Yet
153
Participants
Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-09-13
Completion:
2025-12-31
Conditions
Acute Myeloid Leukemia
Interventions
DRUG
PROCEDURE
No Results Yet
280
Participants
A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2024-11-22
Completion:
2034-03-30
Conditions
Alzheimers Disease
Dementia
Alzheimers Disease, Familial
Interventions
DRUG
No Results Yet
26
Participants
Trial of Suvorexant for Sleep in Children With Autism
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-08-09
Completion:
2028-02-28
Conditions
Autism
Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
76
Participants
A Study of EDG-5506 in Children With Duchenne Muscular Dystrophy (LYNX)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-10-24
Completion:
2027-01-31
Conditions
Duchenne Muscular Dystrophy
Interventions
DRUG
No Results Yet
26
Participants
Trial of Zolpidem for Sleep in Children With Autism
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-08-09
Completion:
2028-04-30
Conditions
Autism
Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
124
Participants
A Study to Learn About the Study Medicine Called PF-07799544 in People With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-11-30
Completion:
2027-02-02
Conditions
Melanoma
Glioma
Thyroid Cancer
Non-Small Cell Lung Cancer
Malignant Neoplasms
Brain Neoplasms
Colorectal Cancer
Interventions
DRUG
No Results Yet
90
Participants
A Study Evaluating the Efficacy and Safety of Cevostamab in Prior B Cell Maturation Antigen (BCMA)-Exposed Participants With Relapsed/Refractory Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-10-17
Completion:
2027-02-26
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
20
Participants
A Study of Imlunestrant (LY3484356) in Healthy Women
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-09-12
Completion:
2022-11-30
Conditions
Healthy
Interventions
DRUG
26
Participants
Trial of Diphenhydramine for Sleep in Children With Autism
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-08-09
Completion:
2027-12-31
Conditions
Autism
Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
102
Participants
JAB-2485 Activity in Adult Patients With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-12-20
Completion:
2026-08-31
Conditions
Solid Tumors
ER+ Breast Cancer
Triple Negative Breast Cancer, TNBC
ARID1A Gene Mutation
Small Cell Lung Cancer, SCLC
Interventions
DRUG
No Results Yet
40
Participants
An Intervention to Enhance Well-Being in Trauma Exposed New Mothers
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-02-13
Completion:
2025-09-01
Conditions
Post-traumatic Stress Disorder
Dissociation
Maternal Care Patterns
Infant Behavior
Maternal Behavior
Maternal Distress
Mood Disturbance
Emotional Regulation
Interventions
DEVICE
No Results Yet
100
Participants
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-11-08
Completion:
2029-01-28
Conditions
Chronic Kidney Disease
Proteinuria
Children
Interventions
DRUG
No Results Yet
27
Participants
A Study of Imlunestrant (LY3484356) in Female Participants With Impaired Liver Function
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-07-05
Completion:
2024-02-28
Conditions
Hepatic Insufficiency
Healthy
Interventions
DRUG
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