Clinical Trials

NCT04851288 | ACTIVE_NOT_RECRUITING | PHASE2

112 Participants

Mitochondrial-targeted Antioxidant Supplementation for Improving Age-related Vascular Dysfunction in Humans

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-04-02

Completion: 2025-12-31

Conditions

Aging

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT04840394 | COMPLETED | PHASE1

1 Participants

Clinical Study of BDB018: Monotherapy and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-06-22

Completion: 2024-03-31

Conditions

Tumor, Solid

Interventions

DRUG

No Results Yet

NCT04819373 | COMPLETED | PHASE2

1 Participants

BDB001-201: A Clinical Study of BDB001 in Patients With PD-(L)1 Refractory Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-08-30

Completion: 2023-04-01

Conditions

Tumor, Solid

Interventions

DRUG

No Results Yet

NCT04808427 | RECRUITING | NA

21 Participants

Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2023-11-20

Completion: 2027-05-01

Conditions

Prostate Cancer

Interventions

DEVICE

No Results Yet

NCT04801420 | COMPLETED | PHASE2

625 Participants

Phase 2 Study Of VLA15, A Vaccine Candidate Against Lyme Borreliosis, In A Healthy Pediatric And Adult Study Population

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-03-08

Completion: 2022-03-25

Conditions

Lyme Borreliosis

Interventions

BIOLOGICAL

Results Available

NCT04798274 | RECRUITING | NA

106 Participants

Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-06-15

Completion: 2027-06-30

Conditions

Autism Spectrum Disorder

Interventions

DEVICE

No Results Yet

NCT04794699 | RECRUITING | PHASE1

180 Participants

Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-04-14

Completion: 2026-12-31

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT04792697 | RECRUITING | NA

100 Participants

Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-05-01

Completion: 2026-03-31

Conditions

Delayed Sleep Phase Syndrome

Interventions

OTHER BEHAVIORAL

No Results Yet

NCT04784715 | ACTIVE_NOT_RECRUITING | PHASE3

1157 Participants

Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-04-26

Completion: 2026-07-06

Conditions

Breast Cancer; HER2-positive; Metastatic

Interventions

DRUG

No Results Yet

NCT04779177 | COMPLETED | PHASE1

26 Participants

Safety, Tolerability, and Pharmacokinetics of Lumateperone in Pediatric Patients With Schizophrenia or Schizoaffective Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-03-12

Completion: 2022-07-30

Conditions

Schizophrenia Pediatric

Interventions

DRUG

Results Available

NCT04777357 | RECRUITING | PHASE3

380 Participants

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-04-28

Completion: 2027-03-31

Conditions

Depression Bipolar I Disorder

Interventions

DRUG

No Results Yet

NCT04771130 | RECRUITING | PHASE1/PHASE2

260 Participants

A Study of BGB-11417 in Participants With Myeloid Malignancies

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-05-24

Completion: 2028-02-08

Conditions

Acute Myeloid Leukemia Myelodysplastic Syndromes Myelodysplastic/Myeloproliferative Neoplasm

Interventions

DRUG

No Results Yet

NCT04752722 | RECRUITING | PHASE1/PHASE2

350 Participants

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-04-22

Completion: 2026-06-30

Conditions

Superficial Bladder Cancer Non-muscle Invasive Bladder Cancer With Carcinoma in Situ

Interventions

DRUG

No Results Yet

NCT04743141 | RECRUITING | PHASE3

600 Participants

Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-04-28

Completion: 2030-07-31

Conditions

Acute Treatment of Migraine

Interventions

DRUG

No Results Yet

NCT04671667 | RECRUITING | PHASE2

188 Participants

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-04-27

Completion: 2029-06-30

Conditions

Recurrent Head and Neck Squamous Cell Carcinoma Recurrent Hypopharyngeal Squamous Cell Carcinoma Recurrent Laryngeal Squamous Cell Carcinoma Recurrent Oral Cavity Squamous Cell Carcinoma Recurrent Oropharyngeal Squamous Cell Carcinoma

Interventions

DRUG PROCEDURE RADIATION BIOLOGICAL

No Results Yet

NCT04657146 | SUSPENDED

40 Participants

Longitudinal Assessment of Marrow and Blood in Patients With Glioblastoma

Study Type: OBSERVATIONAL

Last Updated: 2025-11-12

Start Date: 2024-02-05

Completion: 2027-11-01

Conditions

Glioblastoma

Interventions

OTHER

No Results Yet

NCT04649242 | RECRUITING | PHASE3

2100 Participants

Randomized Study in Children and Adolescents With Migraine: Acute Treatment

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-01-15

Completion: 2029-01-09

Conditions

Pediatric Migraine

Interventions

DRUG

No Results Yet

NCT04647487 | COMPLETED | PHASE1

87 Participants

A Study of LY3484356 in Women With Breast Cancer Before Having Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-04-21

Completion: 2022-11-11

Conditions

Breast Cancer

Interventions

DRUG

Results Available

NCT04628767 | RECRUITING | PHASE2/PHASE3

249 Participants

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-11-12

Completion: 2027-09-30

Conditions

Renal Pelvis and Ureter Urothelial Carcinoma

Interventions

PROCEDURE DRUG BIOLOGICAL

No Results Yet

NCT04628494 | ACTIVE_NOT_RECRUITING | PHASE3

484 Participants

A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-01-13

Completion: 2025-10-13

Conditions

Diffuse Large B-cell Lymphoma

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT04622332 | COMPLETED | PHASE1

45 Participants

A Pilot Study to Assess Safety and Efficacy of SIR1-365 in Patients With Severe COVID-19

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2020-12-18

Completion: 2021-11-27

Conditions

Corona Virus Infection

Interventions

DRUG

Results Available

NCT04614103 | RECRUITING | PHASE2

170 Participants

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2021-05-07

Completion: 2030-12-31

Conditions

Metastatic Non Small Cell Lung Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT04613596 | RECRUITING | PHASE2/PHASE3

806 Participants

Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2020-12-02

Completion: 2028-10-31

Conditions

Advanced Non-Small Cell Lung Cancer Metastatic Non-Small Cell Lung Cancer

Interventions

DRUG

No Results Yet

NCT04606095 | RECRUITING | NA

150 Participants

Explosive Synchronization of Brain Network Activity in Chronic Pain

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2020-11-13

Completion: 2026-02-20

Conditions

Fibromyalgia Healthy Volunteers

Interventions

DIAGNOSTIC_TEST DEVICE

No Results Yet

NCT04561518 | RECRUITING

Study Type: OBSERVATIONAL

Last Updated: 2025-11-12

Start Date: 2020-11-23

Completion: 2024-04-10

Conditions

Neoplasms Solid Tumors Prostate Cancer Lung Cancer Colon Cancer

No Results Yet

NCT04440228 | COMPLETED | NA

90 Participants

TeamSTEPPS in School Mental Health

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2022-05-23

Completion: 2024-04-30

Conditions

Child Behavior Problem Multidisciplinary Communication Interprofessional Relations

Interventions

BEHAVIORAL

Results Available

NCT04415515 | TERMINATED | NA

592023 Participants

Standard Care Coordination Expansion Pilot

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2015-10-31

Completion: 2023-12-31

Conditions

Superutilizers, Health Care Utilization

Interventions

BEHAVIORAL

No Results Yet

NCT04384172 | COMPLETED | NA

9 Participants

Effect of Peripheral Neuromodulation on Vaginal Blood Flow

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2020-11-11

Completion: 2022-03-15

Conditions

Female Sexual Dysfunction Spinal Cord Injuries

Interventions

DEVICE

Results Available

NCT04375072 | COMPLETED | NA

208 Participants

Home-based tDCS and Mindfulness-based Meditation for Self-management of Clinical Pain and Symptoms

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2020-08-13

Completion: 2025-01-30

Conditions

Osteo Arthritis Knee

Interventions

DEVICE

Results Available

NCT04353492 | COMPLETED | PHASE3

562 Participants

An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Fumarate-based RMS Approved Therapies or Fingolimod to Ofatumumab

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2020-07-14

Completion: 2024-10-09

Conditions

Relapsing Multiple Sclerosis

Interventions

BIOLOGICAL

Results Available

NCT04349059 | RECRUITING | NA

46 Participants

The Impact of Dietary Pattern on Erectile Function

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2023-10-30

Completion: 2026-12-31

Conditions

Erectile Dysfunction

Interventions

OTHER

No Results Yet

NCT04325828 | ACTIVE_NOT_RECRUITING | PHASE2

31 Participants

A Study of Apalutamide Combined With GnRH Agonist in Participants With Androgen Receptor Positive Salivary Gland Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-12

Start Date: 2020-04-07

Completion: 2021-06-09

Conditions

Salivary Gland Neoplasms

Interventions

DRUG

Results Available