Clinical Trials

NCT04305431 | RECRUITING | NA
55 Participants

Dietary Behavior Intervention in African Americans at Risk for Cardiovascular Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-02-25
Completion: 2026-12-19
Conditions
Diet Cooking
Interventions
BEHAVIORAL
No Results Yet
NCT04272086 | COMPLETED | PHASE4
140 Participants

Utility of Liposomal Bupivacaine Transversus Abdominal Plane Block for Open Myomectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-11-09
Completion: 2025-10-28
Conditions
Fibroid Uterus
Interventions
DRUG
No Results Yet
NCT04240821 | ENROLLING_BY_INVITATION | PHASE2
34 Participants

Theophylline for Treatment of Pseudohypoparathyroidism

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-05-22
Completion: 2026-12-31
Conditions
Pseudohypoparathyroidism Pseudohypoparathyroidism Type 1a Albright Hereditary Osteodystrophy
Interventions
DRUG
No Results Yet
NCT04228367 | RECRUITING | NA
104 Participants

JuggerStitch Post Market Clinical Follow-up Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-09-25
Completion: 2026-03-31
Conditions
Meniscus Tear, Tibial Meniscus Lesion
Interventions
DEVICE
No Results Yet
NCT04221438 | TERMINATED | PHASE2
3 Participants

Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-09-22
Completion: 2024-06-10
Conditions
Melanoma of Unknown Primary Metastatic Malignant Neoplasm in Lymph Node Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 Pathologic Stage IIID Cutaneous Melanoma AJCC v8 Recurrent Cutaneous Melanoma
Interventions
DRUG PROCEDURE OTHER
NCT04216290 | ACTIVE_NOT_RECRUITING | PHASE2
95 Participants

A Study of Chemotherapy and Radiation Therapy Compared to Chemotherapy and Radiation Therapy Plus MEDI4736 (Durvalumab) Immunotherapy for Bladder Cancer Which Has Spread to the Lymph Nodes, INSPIRE Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-03-17
Completion: 2026-06-30
Conditions
Bladder Urothelial Carcinoma Stage III Bladder Cancer AJCC v8
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER RADIATION
No Results Yet
NCT04214067 | ACTIVE_NOT_RECRUITING | PHASE3
168 Participants

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to the Usual Radiation Treatment for Newly Diagnosed Early Stage High Intermediate Risk Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-04-09
Completion: 2025-12-30
Conditions
Endometrial Endometrioid Adenocarcinoma Stage I Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8 Stage II Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Interventions
PROCEDURE RADIATION BIOLOGICAL OTHER
No Results Yet
NCT04204616 | ACTIVE_NOT_RECRUITING | PHASE3
500 Participants

A Long-term Study of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-01-11
Completion: 2026-10-26
Conditions
Prurigo Nodularis
Interventions
DRUG
No Results Yet
NCT04198870 | ACTIVE_NOT_RECRUITING | NA
500 Participants

MitraClip REPAIR MR Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-07-21
Completion: 2027-12-31
Conditions
Mitral Valve Regurgitation
Interventions
DEVICE PROCEDURE
No Results Yet
NCT04196530 | COMPLETED | PHASE1
40 Participants

BDB001-102: Open Label Dose Escalation of BDB001 in Combination w Atezolizumab

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-11-21
Completion: 2024-07-31
Conditions
Tumor, Solid
Interventions
DRUG
No Results Yet
NCT04196374 | COMPLETED | NA
48 Participants

Return of Genomic Results and Aggregate Penetrance in Population-Based Cohorts

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-06-09
Completion: 2025-05-30
Conditions
Seemingly Healthy Genetic Predisposition to Disease
Interventions
GENETIC
No Results Yet
NCT04166409 | RECRUITING | PHASE3
170 Participants

A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-01-31
Completion: 2030-12-31
Conditions
Low Grade Astrocytoma Low Grade Glioma Metastatic Low Grade Astrocytoma Metastatic Low Grade Glioma WHO Grade 1 Glioma WHO Grade 2 Glioma
Interventions
PROCEDURE DRUG OTHER
No Results Yet
NCT04150614 | RECRUITING | PHASE4
90 Participants

BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-05-14
Completion: 2026-07-31
Conditions
Nausea With Vomiting Chemotherapy-Induced
Interventions
DRUG
No Results Yet
NCT04145141 | RECRUITING
500 Participants

National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2021-07-28
Completion: 2025-12-31
Conditions
Hepatocellular Carcinoma Liver Cancer Cholangiocarcinoma
No Results Yet
NCT04122976 | ACTIVE_NOT_RECRUITING
805 Participants

A Study in Which Non-metastatic Castration-resistant Prostate Cancer (nmCRPC) Patients for Whom a Decision to Treat With Darolutamide Has Been Made Before Enrollment Are Observed and Certain Outcomes Are Described

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2020-01-30
Completion: 2026-07-07
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT04122196 | COMPLETED | PHASE2/PHASE3
118 Participants

Perioperative Pregabalin in Ureteroscopy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-06-01
Completion: 2023-07-01
Conditions
Kidney Stone Pain, Postoperative Addiction Opioid Use
Interventions
DRUG
NCT04115306 | RECRUITING | PHASE1/PHASE2
61 Participants

Phase 1/1b/2 Study of Oral PMD-026 in Patients With Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-11-14
Completion: 2026-09-30
Conditions
Metastatic Breast Cancer
Interventions
DRUG
No Results Yet
NCT04102371 | ACTIVE_NOT_RECRUITING | PHASE3
8800 Participants

Pragmatic Pediatric Trial of Balanced Versus Normal Saline Fluid in Sepsis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-08-25
Completion: 2026-01-31
Conditions
Shock Septic
Interventions
DRUG
No Results Yet
NCT04083976 | ACTIVE_NOT_RECRUITING | PHASE2
316 Participants

A Study of Erdafitinib in Participants With Advanced Solid Tumors and Fibroblast Growth Factor Receptor (FGFR) Gene Alterations

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-11-20
Completion: 2023-12-04
Conditions
Advanced Solid Tumor
Interventions
DRUG
NCT04074512 | AVAILABLE

Copper Histidinate Treatment for Menkes Disease

Study Type: EXPANDED_ACCESS
Last Updated: 2025-11-12
Conditions
Menkes Disease
Interventions
DRUG
No Results Yet
NCT04064060 | RECRUITING | PHASE3
665 Participants

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-08-12
Completion: 2028-05-12
Conditions
Myelodysplastic Syndromes (MDS) Beta-thalassemia Myeloproliferative Neoplasm(MPN)-Associated Myelofibrosis
Interventions
DRUG
No Results Yet
NCT04033445 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
1064 Participants

A Study of Guselkumab in Participants With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-09-26
Completion: 2023-09-19
Conditions
Ulcerative Colitis
Interventions
DRUG
NCT04026386 | RECRUITING | NA
75 Participants

A Center Based Early Intervention Program For Preschoolers With Developmental Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-10-19
Completion: 2034-12-30
Conditions
Development Disorder, Child Developmental Disability Development Delay Autism Spectrum Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT04008797 | RECRUITING | PHASE1/PHASE2
301 Participants

A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-07-11
Completion: 2027-08-31
Conditions
Endometrial Neoplasms Neoplasms Carcinoma, Hepatocellular Liver Neoplasms Colorectal Neoplasms
Interventions
DRUG
No Results Yet
NCT04008368 | RECRUITING | PHASE1/PHASE2
32 Participants

Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-10-24
Completion: 2030-01-30
Conditions
Myeloid Chimerism
Interventions
DEVICE
No Results Yet
NCT04001829 | ACTIVE_NOT_RECRUITING | PHASE2
249 Participants

Taxane and Taxane-Induced Peripheral Neuropathy in African American Patients With Stage I-III Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-08-09
Completion: 2023-09-19
Conditions
Anatomic Stage I Breast Cancer AJCC v8 Anatomic Stage IA Breast Cancer AJCC v8 Anatomic Stage IB Breast Cancer AJCC v8 Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage IIA Breast Cancer AJCC v8 Anatomic Stage IIB Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IIIA Breast Cancer AJCC v8 Anatomic Stage IIIB Breast Cancer AJCC v8 Anatomic Stage IIIC Breast Cancer AJCC v8 Invasive Breast Carcinoma Prognostic Stage I Breast Cancer AJCC v8 Prognostic Stage IA Breast Cancer AJCC v8 Prognostic Stage IB Breast Cancer AJCC v8 Prognostic Stage II Breast Cancer AJCC v8 Prognostic Stage IIA Breast Cancer AJCC v8 Prognostic Stage IIB Breast Cancer AJCC v8 Prognostic Stage III Breast Cancer AJCC v8 Prognostic Stage IIIA Breast Cancer AJCC v8 Prognostic Stage IIIB Breast Cancer AJCC v8 Prognostic Stage IIIC Breast Cancer AJCC v8
Interventions
DRUG OTHER
NCT03987386 | ACTIVE_NOT_RECRUITING | PHASE3
186 Participants

Conventional or Hypofractionated Radiation Therapy in Treating Patients With Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-05-30
Completion: 2027-11-01
Conditions
Stage I Prostate Cancer AJCC v8 Stage II Prostate Cancer AJCC v8 Stage III Prostate Cancer AJCC v8 Stage IVA Prostate Cancer AJCC v8
Interventions
RADIATION OTHER
No Results Yet
NCT03986021 | RECRUITING
400 Participants

Reproductive Axis Maturation in the Early Post-Menarchal Years

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2019-12-19
Completion: 2029-07-01
Conditions
Reproductive Physiological Processes Pediatrics Adolescent Health Adolescent Development
No Results Yet
NCT03979508 | TERMINATED | PHASE2
26 Participants

Abemaciclib in Treating Patients With Surgically Resectable, Chemotherapy Resistant, Triple Negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-01-10
Completion: 2024-12-26
Conditions
Anatomic Stage I Breast Cancer AJCC v8 Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8 Breast Ductal Carcinoma In Situ Breast Fibrocystic Change Breast Lobular Carcinoma In Situ Invasive Breast Carcinoma Prognostic Stage I Breast Cancer AJCC v8 Prognostic Stage IA Breast Cancer AJCC v8 Prognostic Stage IB Breast Cancer AJCC v8 Prognostic Stage II Breast Cancer AJCC v8 Prognostic Stage IIA Breast Cancer AJCC v8 Prognostic Stage IIB Breast Cancer AJCC v8 Prognostic Stage III Breast Cancer AJCC v8 Prognostic Stage IIIA Breast Cancer AJCC v8 Prognostic Stage IIIB Breast Cancer AJCC v8 Prognostic Stage IIIC Breast Cancer AJCC v8 Triple-Negative Breast Carcinoma
Interventions
DRUG PROCEDURE
No Results Yet
NCT03970603 | COMPLETED | NA
40 Participants

Syndesmosis Ankle Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-10-15
Completion: 2023-10-26
Conditions
Syndesmotic Disruption Weight-bearing Status
Interventions
OTHER
No Results Yet
NCT03950817 | COMPLETED | PHASE4
80 Participants

Nebulized Sub-dissociative Dose Ketamine at Three Different Dosing Regimens for Treating Acute Pain in the Pediatric ED

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-05-13
Completion: 2024-09-24
Conditions
Pain
Interventions
DRUG
NCT03942770 | ACTIVE_NOT_RECRUITING | NA
91 Participants

Remote Alcohol Monitoring to Facilitate Abstinence From Alcohol: Exp 2

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-07-15
Completion: 2025-09-01
Conditions
Alcohol Use Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT03916419 | COMPLETED | PHASE2
26 Participants

Magnetic Resonance-Guided Hypofractionated Adaptive Radiation Therapy With Concurrent Chemotherapy and Consolidation Durvalumab for Inoperable Stage IIB, IIIA, and Select IIIB and IIIC Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-06-20
Completion: 2025-09-28
Conditions
Stage IIB Non-Small Cell Lung Cancer Stage IIIA Non-small Cell Lung Cancer Stage IIIB Non-small Cell Lung Cancer Stage IIIC Non-Small Cell Lung Cancer
Interventions
DEVICE RADIATION DRUG BIOLOGICAL
No Results Yet
NCT03911557 | COMPLETED | PHASE2
14 Participants

Durvalumab and Tremelimumab Combination in Somatically Hypermutated Recurrent Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-06-08
Completion: 2025-10-10
Conditions
Tumor, Solid
Interventions
DRUG
No Results Yet
NCT03907488 | ACTIVE_NOT_RECRUITING | PHASE3
994 Participants

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-08-29
Completion: 2024-03-31
Conditions
Ann Arbor Stage III Hodgkin Lymphoma Ann Arbor Stage III Lymphocyte-Depleted Classic Hodgkin Lymphoma Ann Arbor Stage III Mixed Cellularity Classic Hodgkin Lymphoma Ann Arbor Stage III Nodular Sclerosis Classic Hodgkin Lymphoma Ann Arbor Stage IV Hodgkin Lymphoma Ann Arbor Stage IV Lymphocyte-Depleted Classic Hodgkin Lymphoma Ann Arbor Stage IV Mixed Cellularity Classic Hodgkin Lymphoma Ann Arbor Stage IV Nodular Sclerosis Classic Hodgkin Lymphoma Classic Hodgkin Lymphoma Lymphocyte-Rich Classic Hodgkin Lymphoma
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER RADIATION
NCT03893318 | TERMINATED | PHASE4
15 Participants

IV Lidocaine in Pediatric AIS

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-07-30
Completion: 2024-12-31
Conditions
Systemic Lidocaine Improves Pain Control After Surgery by Attenuating the Systemic Inflammatory Response to Surgery
Interventions
DRUG
NCT03883126 | ACTIVE_NOT_RECRUITING | NA
211 Participants

Remote Alcohol Monitoring to Facilitate Abstinence From Alcohol: Exp 1

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2020-06-16
Completion: 2025-09-01
Conditions
Alcohol Use Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT03866668 | RECRUITING | PHASE2
25 Participants

A Study of Esomeprazole in Children With Autism

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2019-05-29
Completion: 2028-12-31
Conditions
Autism Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
NCT03846830 | COMPLETED | NA
24 Participants

Incremental Velocity Error as a New Treatment in Vestibular Rehabilitation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2021-10-11
Completion: 2025-04-01
Conditions
Mild Traumatic Brain Injury Vestibular Neuropathy
Interventions
DEVICE BEHAVIORAL
No Results Yet
NCT03838627 | COMPLETED
34 Participants

Feasibility and Agreement of Remote Evaluation of Resting Heart Rate and Heart Rate Variability in Survivors of Hodgkin Lymphoma Treated With Chest Radiation (PILOT STUDY-SURVIVOR)

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2019-02-05
Completion: 2021-01-19
Conditions
Hodgkin Disease
No Results Yet
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