Clinical Trials
3062
Participants
Sleep for Stroke Management and Recovery Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2019-05-09
Completion:
2026-11-30
Conditions
Ischemic Stroke
Sleep Apnea
Sleep Apnea, Obstructive
Stroke
CPAP
Telemedicine
Home Sleep Apnea Test
Randomized Clinical Trial
Multicenter Trial
Interventions
DEVICE
No Results Yet
636
Participants
Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2019-08-16
Completion:
2027-01-01
Conditions
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Interventions
PROCEDURE
DRUG
OTHER
RADIATION
BIOLOGICAL
No Results Yet
500
Participants
Men at High Genetic Risk for Prostate Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2019-03-27
Completion:
2029-01-01
Conditions
Prostatic Neoplasms
No Results Yet
620
Participants
Healthy Eating and Active Living Taught at Home (HEALTH) Dissemination & Implementation (D&I)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2019-01-25
Completion:
2024-07-31
Conditions
Obesity
Interventions
BEHAVIORAL
40
Participants
Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2019-01-07
Completion:
2022-05-01
Conditions
Cervical Adenocarcinoma
Cervical Adenosquamous Carcinoma
Cervical Squamous Cell Carcinoma
Stage IB2 Cervical Cancer AJCC v8
Stage II Cervical Cancer AJCC v8
Stage IIA Cervical Cancer AJCC v8
Stage IIA1 Cervical Cancer AJCC v8
Stage IIA2 Cervical Cancer AJCC v8
Stage IIB Cervical Cancer AJCC v8
Stage IIIB Cervical Cancer AJCC v8
Stage IVA Cervical Cancer AJCC v8
Interventions
DRUG
RADIATION
40
Participants
Serial Amnioinfusions as Regenerative Therapy for Pulmonary Hypoplasia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-10-01
Completion:
2026-12-31
Conditions
Renal Failure Congenital
Congenital Renal Anomaly Nos
Renal Agenesis and Dysgenesis
Lower Urinary Tract Obstructive Syndrome
Interventions
DRUG
No Results Yet
288
Participants
Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-09-27
Completion:
2024-12-06
Conditions
Endometrial Adenocarcinoma
Endometrial Mixed Cell Adenocarcinoma
Endometrial Serous Adenocarcinoma
Endometrial Undifferentiated Carcinoma
Endometrioid Adenocarcinoma
Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Interventions
PROCEDURE
DRUG
BIOLOGICAL
139
Participants
A Study of Subcutaneous Nivolumab Monotherapy With or Without Recombinant Human Hyaluronidase PH20 (rHuPH20)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-10-29
Completion:
2022-09-07
Conditions
Neoplasms by Site
Interventions
BIOLOGICAL
DRUG
1055
Participants
This is an Extension Study of the Roche P-trials to Investigate Safety and Effectiveness of Ocrelizumab in Participants With Multiple Sclerosis (MS)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-07-12
Completion:
2025-07-17
Conditions
Multiple Sclerosis
Interventions
DRUG
No Results Yet
15
Participants
A Study to Compare Treatments for a Type of Kidney Cancer Called TFE/Translocation Renal Cell Carcinoma (tRCC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2019-01-08
Completion:
2024-09-30
Conditions
Metastatic Renal Cell Carcinoma
Stage III Renal Cell Cancer AJCC v8
Stage IV Renal Cell Cancer AJCC v8
TFE3-Rearranged Renal Cell Carcinoma
Unresectable Renal Cell Carcinoma
Interventions
DRUG
BIOLOGICAL
22
Participants
A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2019-03-13
Completion:
2027-05-03
Conditions
FLT3-mutated Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
15
Participants
Pembrolizumab With Combination Chemotherapy in Treating Participants With Locally Advanced or Metastatic Small Cell/Neuroendocrine Cancers of Urothelium or Prostate
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2019-01-11
Completion:
2025-12-01
Conditions
Bladder Small Cell Neuroendocrine Carcinoma
Castration-Resistant Prostate Carcinoma
Metastatic Bladder Urothelial Carcinoma
Metastatic Urethral Urothelial Carcinoma
Prostate Carcinoma Metastatic in the Bone
Prostate Neuroendocrine Neoplasm
Prostate Small Cell Carcinoma
Stage III Bladder Cancer American Joint Committee on Cancer ( AJCC) v8
Stage III Prostate Cancer AJCC v8
Stage III Urethral Cancer AJCC v8
Stage IV Bladder Cancer AJCC v8
Stage IV Prostate Cancer AJCC v8
Stage IV Urethral Cancer AJCC v8
Stage IVA Bladder Cancer AJCC v8
Stage IVB Bladder Cancer AJCC v8
Ureter Small Cell Carcinoma
Urothelial Carcinoma
Interventions
DRUG
BIOLOGICAL
800
Participants
Study of the Safety and Effectiveness of Motiva Implants®
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-04-06
Completion:
2032-08-30
Conditions
Breast Implants
Interventions
DEVICE
No Results Yet
19
Participants
A Study of Androgen Receptor (AR) Antagonist Apalutamide in Chinese Participants With Metastatic Castration-Resistant Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-08-31
Completion:
2019-07-09
Conditions
Prostatic Neoplasms
Interventions
DRUG
No Results Yet
565
Participants
Financial Burden Assessment in Patients With Stage I-III Colon or Rectal Cancer Undergoing Treatment
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2018-06-11
Completion:
2023-12-31
Conditions
Stage I Colon Cancer AJCC v8
Stage I Rectal Cancer AJCC v8
Stage II Colon Cancer AJCC v8
Stage II Rectal Cancer AJCC v8
Stage IIA Colon Cancer AJCC v8
Stage IIA Rectal Cancer AJCC v8
Stage IIB Colon Cancer AJCC v8
Stage IIB Rectal Cancer AJCC v8
Stage IIC Colon Cancer AJCC v8
Stage IIC Rectal Cancer AJCC v8
Stage III Colon Cancer AJCC v8
Stage III Rectal Cancer AJCC v8
Stage IIIA Colon Cancer AJCC v8
Stage IIIA Rectal Cancer AJCC v8
Stage IIIB Colon Cancer AJCC v8
Stage IIIB Rectal Cancer AJCC v8
Stage IIIC Colon Cancer AJCC v8
Stage IIIC Rectal Cancer AJCC v8
Interventions
OTHER
9
Participants
Pembrolizumab in Untreated B-Cell Non-Hodgkin Lymphoproliferative Diseases
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-07-09
Completion:
2021-06-09
Conditions
Follicular Lymphoma
Indolent B-Cell Non-Hodgkin Lymphoma
Marginal Zone Lymphoma
Interventions
OTHER
BIOLOGICAL
63
Participants
A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertension
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-07-23
Completion:
2022-03-28
Conditions
Pulmonary Arterial Hypertension
Interventions
DRUG
87
Participants
BDB001-101: Clinical Study of BDB001 as a Mono-therapy or in Combination With Pembrolizumab
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-02-15
Completion:
2024-03-31
Conditions
Tumor, Solid
Interventions
DRUG
No Results Yet
31
Participants
Automated Abdominal Binder for Orthostatic Hypotension
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-03-01
Completion:
2026-07-01
Conditions
Orthostatic Hypotension
Autonomic Failure
Pure Autonomic Failure
Multiple System Atrophy
Interventions
DEVICE
DRUG
No Results Yet
125
Participants
A Study of Erdafitinib in Participants With Metastatic or Locally Advanced Urothelial Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-04-05
Completion:
2022-09-30
Conditions
Urothelial Carcinoma
Interventions
DRUG
1409
Participants
A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-04-13
Completion:
2023-10-20
Conditions
Crohn's Disease
Interventions
DRUG
136
Participants
A Study of Niraparib Combination Therapies for the Treatment of Metastatic Castration-Resistant Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-03-02
Completion:
2021-08-31
Conditions
Prostatic Neoplasms, Castration-Resistant
Interventions
DRUG
48
Participants
Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2018-06-21
Completion:
2027-12-31
Conditions
Anesthesia
Intravenous Fluid
Blood Pressure
Interventions
OTHER
No Results Yet
298
Participants
Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-10-26
Completion:
2023-08-23
Conditions
Lung Neuroendocrine Tumor
Lung Neuroendocrine Tumor G2
Metastatic Digestive System Neuroendocrine Neoplasm
Functioning Pancreatic Neuroendocrine Tumor
Intermediate Grade Lung Neuroendocrine Neoplasm
Locally Advanced Digestive System Neuroendocrine Neoplasm
Locally Advanced Digestive System Neuroendocrine Tumor G1
Locally Advanced Lung Neuroendocrine Neoplasm
Locally Advanced Pancreatic Neuroendocrine Tumor
Locally Advanced Unresectable Digestive System Neuroendocrine Neoplasm
Low Grade Lung Neuroendocrine Neoplasm
Metastatic Digestive System Neuroendocrine Tumor G1
Metastatic Lung Neuroendocrine Neoplasm
Metastatic Lung Neuroendocrine Tumor
Metastatic Pancreatic Neuroendocrine Neoplasm
Metastatic Pancreatic Neuroendocrine Tumor
Metastatic Thymus Neuroendocrine Neoplasm
Neuroendocrine Neoplasm
Neuroendocrine Tumor
Neuroendocrine Tumor G2
Non-Functioning Pancreatic Neuroendocrine Tumor
Pancreatic Serotonin-Producing Neuroendocrine Tumor
Thymus Neuroendocrine Tumor
Unresectable Digestive System Neuroendocrine Neoplasm
Unresectable Digestive System Neuroendocrine Tumor G1
Unresectable Lung Neuroendocrine Neoplasm
Unresectable Pancreatic Neuroendocrine Neoplasm
Unresectable Thymus Neuroendocrine Neoplasm
Interventions
PROCEDURE
DRUG
OTHER
595
Participants
A Study of the Efficacy and Safety of Atezolizumab Plus Chemotherapy for Patients With Early Relapsing Recurrent Triple-Negative Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-01-11
Completion:
2024-10-23
Conditions
Triple Negative Breast Neoplasms
Interventions
DRUG
135
Participants
Dexamethasone in Controlling Dyspnea in Patients With Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2017-12-04
Completion:
2021-05-05
Conditions
Dyspnea
Malignant Neoplasm
Interventions
DRUG
OTHER
124
Participants
Modular Study to Evaluate CT7001 Alone in Cancer Patients With Advanced Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2017-11-14
Completion:
2022-12-15
Conditions
Advanced Solid Malignancies
Interventions
DRUG
No Results Yet
434
Participants
Obstructive Sleep Apnea in Survivors of Hodgkin Lymphoma Treated With Thoracic Radiation
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2018-01-23
Completion:
2023-07-31
Conditions
Obstructive Sleep Apnea
Hodgkin Lymphoma
No Results Yet
62
Participants
Tazemetostat in Treating Patients With Recurrent Ovarian or Endometrial Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2019-05-01
Completion:
2023-07-28
Conditions
Recurrent Endometrial Endometrioid Adenocarcinoma
Recurrent Malignant Uterine Corpus Neoplasm
Recurrent Ovarian Carcinoma
Recurrent Ovarian Clear Cell Adenocarcinoma
Recurrent Ovarian Endometrioid Adenocarcinoma
Interventions
PROCEDURE
DRUG
9
Participants
Testing the Addition of Radiation Therapy to Immunotherapy for Merkel Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-06-12
Completion:
2022-06-07
Conditions
Advanced Merkel Cell Carcinoma
Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8
Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8
Metastatic Merkel Cell Carcinoma
Pathologic Stage III Cutaneous Merkel Cell Carcinoma AJCC v8
Pathologic Stage IIIA Cutaneous Merkel Cell Carcinoma AJCC v8
Pathologic Stage IIIB Cutaneous Merkel Cell Carcinoma AJCC v8
Pathologic Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8
Interventions
BIOLOGICAL
RADIATION
68
Participants
Developing a Dyadic Intervention for Sexually Transmitted Infection (STI)/HIV Prevention in Youth
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-01-15
Completion:
2021-10-01
Conditions
Exposure to Sexually Transmissible Disorder (Event)
Interventions
BEHAVIORAL
202
Participants
Simplified Patient Care Strategy in Decreasing Early Death in Patients With Acute Promyelocytic Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2017-09-26
Completion:
2023-04-27
Conditions
Acute Promyelocytic Leukemia With PML-RARA
t(15;17)
Interventions
OTHER
1376
Participants
Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2017-07-31
Completion:
2025-03-31
Conditions
Advanced Malignant Solid Neoplasm
Ann Arbor Stage III Non-Hodgkin Lymphoma
Ann Arbor Stage IV Non-Hodgkin Lymphoma
Histiocytic Sarcoma
Juvenile Xanthogranuloma
Langerhans Cell Histiocytosis
Malignant Glioma
Recurrent Childhood Rhabdomyosarcoma
Recurrent Ependymoma
Recurrent Ewing Sarcoma
Recurrent Glioma
Recurrent Hepatoblastoma
Recurrent Langerhans Cell Histiocytosis
Recurrent Malignant Germ Cell Tumor
Recurrent Malignant Solid Neoplasm
Recurrent Medulloblastoma
Recurrent Neuroblastoma
Recurrent Non-Hodgkin Lymphoma
Recurrent Osteosarcoma
Recurrent Peripheral Primitive Neuroectodermal Tumor
Recurrent Primary Central Nervous System Neoplasm
Recurrent Rhabdoid Tumor
Recurrent Soft Tissue Sarcoma
Refractory Ewing Sarcoma
Refractory Glioma
Refractory Hepatoblastoma
Refractory Langerhans Cell Histiocytosis
Refractory Malignant Germ Cell Tumor
Refractory Malignant Solid Neoplasm
Refractory Medulloblastoma
Refractory Neuroblastoma
Refractory Non-Hodgkin Lymphoma
Refractory Osteosarcoma
Refractory Peripheral Primitive Neuroectodermal Tumor
Refractory Primary Central Nervous System Neoplasm
Refractory Rhabdoid Tumor
Refractory Rhabdomyosarcoma
Rhabdoid Tumor
Stage III Osteosarcoma AJCC v7
Stage III Soft Tissue Sarcoma AJCC v7
Stage IV Osteosarcoma AJCC v7
Stage IV Soft Tissue Sarcoma AJCC v7
Stage IVA Osteosarcoma AJCC v7
Stage IVB Osteosarcoma AJCC v7
Wilms Tumor
Interventions
PROCEDURE
DRUG
OTHER
No Results Yet
36
Participants
Tesamorelin to Improve Functional Outcomes After Peripheral Nerve Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2018-06-01
Completion:
2027-12-31
Conditions
Peripheral Nerve Injuries
Interventions
DRUG
No Results Yet
48
Participants
Osimertinib and Gefitinib in EGFR Inhibitor naïve Advanced EGFR Mutant Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2017-05-09
Completion:
2026-10-31
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
8000
Participants
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2017-03-10
Completion:
2026-12-31
Conditions
Lumbar Spinal Stenosis
Interventions
DEVICE
No Results Yet
85
Participants
Clinical and Physiological Studies of Tremor Syndromes
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2017-05-05
Completion:
2022-03-23
Conditions
Parkinson Disease
Dystonia
Essential Tremor
No Results Yet
17
Participants
Trial of Nivolumab as a Novel Neoadjuvant Pre-Surgical Therapy for Locally Advanced Oral Cavity Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2017-05-30
Completion:
2021-11-15
Conditions
Oral Cavity SCC
Interventions
DRUG
43
Participants
An Extension Protocol for Subjects Who Successfully Completed PRO140_CD02 or PRO140_CD02_Open Label Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2016-11-03
Completion:
2022-06-30
Conditions
Human Immunodeficiency Virus (HIV)
Interventions
DRUG
43
Participants
Continuous Non-Invasive SpHb and PVI Monitoring on Intra-Operative and Post-Surgical Clinical Outcomes
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2016-12-15
Completion:
2018-08-31
Conditions
Surgery
Interventions
DEVICE
Showing 40 trials per page · Total 557382 trials