Clinical Trials

NCT05602142 | NOT_YET_RECRUITING | PHASE1/PHASE2
20 Participants

Study of [11C]CPPC as a Clinical PET Radioligand Biomarker of Microglial Activation in ALS

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-02-28
Completion: 2027-01-31
Conditions
ALS
Interventions
DRUG
No Results Yet
NCT05595642 | RECRUITING | PHASE3
1290 Participants

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-12-29
Completion: 2025-06-24
Conditions
Chronic Obstructive Pulmonary Disease (COPD)
Interventions
DRUG
No Results Yet
NCT05592015 | RECRUITING | PHASE2
28 Participants

Ruxolitinib for the Treatment of T-Cell Large Granular Lymphocytic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-05-03
Completion: 2025-12-31
Conditions
T-Cell Large Granular Lymphocyte Leukemia
Interventions
DRUG
No Results Yet
NCT05588167 | RECRUITING
100 Participants

Establishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type C

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-28
Completion: 2026-09-30
Conditions
Niemann-Pick Disease, Type C
No Results Yet
NCT05582889 | COMPLETED | NA
64 Participants

Move For Your Health for Older Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-04
Completion: 2024-03-01
Conditions
Cancer Survivors
Interventions
BEHAVIORAL
NCT05580458 | RECRUITING | PHASE1/PHASE2
225 Participants

Safety and Immunogenicity of Recombinant Varicella Zoster Virus Vaccine in People With HIV Who Have a CD4 Count Less Than 300 or Greater Than or Equal to 300 and a Healthy Control Population

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-03-13
Completion: 2027-02-01
Conditions
Herpes Zoster
Interventions
BIOLOGICAL
No Results Yet
NCT05576090 | RECRUITING | NA
240 Participants

UCLA REST Study (REsearch on Sleep Techniques)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-04-03
Completion: 2026-06-30
Conditions
Sleep Disturbance Inflammation Psychosocial Functioning
Interventions
BEHAVIORAL
No Results Yet
NCT05570747 | COMPLETED
35 Participants

Simulated In-House Usability Study of Eclipse Continuous Positive Airway Pressure (CPAP) Device

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-19
Completion: 2022-11-11
Conditions
Obstructive Sleep Apnea
Interventions
OTHER
NCT05569122 | RECRUITING | PHASE1
90 Participants

Applying pGz in Mitochondrial Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-03-22
Completion: 2027-09-30
Conditions
Mitochondrial Myopathies Mitochondrial Diseases
Interventions
DIAGNOSTIC_TEST DEVICE DRUG
No Results Yet
NCT05568888 | TERMINATED | PHASE3
1366 Participants

Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( TAP Study )

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-03-28
Completion: 2024-10-29
Conditions
Traumatic Injury
Interventions
DRUG
NCT05559047 | COMPLETED
70 Participants

Field Usability Study of Eclipse Mask

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-10
Completion: 2023-01-25
Conditions
Obstructive Sleep Apnea
Interventions
DEVICE
NCT05558904 | RECRUITING | PHASE1/PHASE2
60 Participants

An Investigational Scan (Me-4FDG PET/CT) for the Detection of Sodium-Glucose Transport for Early Diagnosis of Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-01-19
Completion: 2026-10-01
Conditions
Lung Adenocarcinoma
Interventions
DRUG PROCEDURE OTHER
No Results Yet
NCT05554406 | RECRUITING | PHASE2
335 Participants

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-09-25
Completion: 2027-03-31
Conditions
Acute Myeloid Leukemia Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm Acute Myeloid Leukemia Post Cytotoxic Therapy Acute Myeloid Leukemia, Myelodysplasia-Related
Interventions
DRUG PROCEDURE
No Results Yet
NCT05552222 | RECRUITING | PHASE3
1590 Participants

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-25
Completion: 2031-04-30
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05546658 | RECRUITING | EARLY_PHASE1
30 Participants

Effects of Psilocybin in Obsessive Compulsive Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-28
Completion: 2026-09-12
Conditions
Obsessive-Compulsive Disorder
Interventions
DRUG
No Results Yet
NCT05543681 | RECRUITING | PHASE2
164 Participants

Clinical Trial on Agitation in Alzheimer's Dementia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-11
Completion: 2026-03-30
Conditions
Alzheimer Disease Agitation,Psychomotor Care Giving Burden NPS Aggression
Interventions
DRUG
No Results Yet
NCT05534932 | ACTIVE_NOT_RECRUITING | NA
20 Participants

Guideline-directed Management and Therapy (GDMT) for the Prevention of Postpartum Cardiac Dysfunction in Preeclamptic African American Women

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-27
Completion: 2026-07-01
Conditions
Preeclampsia Postpartum
Interventions
DEVICE
No Results Yet
NCT05532657 | ACTIVE_NOT_RECRUITING | PHASE3
629 Participants

ACHIEVE Brain Health Follow-Up Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-01-12
Completion: 2026-06-30
Conditions
Aging Cognitive Decline Mild Cognitive Impairment Dementia Hearing Loss
Interventions
OTHER
No Results Yet
NCT05523947 | RECRUITING | PHASE1/PHASE2
137 Participants

Clinical Trial of YH32367 in Patients With HER2 Positive Locally Advanced or Metastatic Solid Tumor

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-08-26
Completion: 2026-10-01
Conditions
HER2-Positive Solid Tumor
Interventions
DRUG
No Results Yet
NCT05522075 | RECRUITING | NA
55 Participants

Reducing Blood Pressure in Mid-life Adult Binge Drinkers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-21
Completion: 2026-04-30
Conditions
Alcohol Drinking Binge Drinking Blood Pressure Alcohol Abstinence Aging Lifestyle Factors Vasodilation Behavioral Problem
Interventions
BEHAVIORAL
No Results Yet
NCT05509582 | WITHDRAWN | PHASE2
0 Participants

Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated Cytopenias

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-11-07
Completion: 2025-11-07
Conditions
Immune Mediated Anemia Immune Mediated Thrombocytopenia Chronic GVHD
Interventions
DRUG
No Results Yet
NCT05505110 | RECRUITING | EARLY_PHASE1
20 Participants

MOdification Of THe Early-Life Respiratory Microbiome Through Vaginal SEEDing

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-09
Completion: 2028-08-10
Conditions
C-section Vaginal Seeding Respiratory Microbiome
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT05500586 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
21 Participants

The Effects of Glucagon on Hepatic Metabolism

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-20
Completion: 2025-09-30
Conditions
Obesity Type2diabetes NAFLD
Interventions
DRUG
No Results Yet
NCT05498428 | RECRUITING | PHASE2
520 Participants

A Study of Amivantamab in Participants With Advanced or Metastatic Solid Tumors Including Epidermal Growth Factor Receptor (EGFR)-Mutated Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-11
Completion: 2027-08-17
Conditions
Carcinoma, Non-small-Cell Lung
Interventions
DRUG
No Results Yet
NCT05492942 | COMPLETED | NA
134 Participants

Records for Alcohol Care Enhancement

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-11
Completion: 2024-10-17
Conditions
Alcohol Use Disorder (AUD)
Interventions
BEHAVIORAL
NCT05488314 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
57 Participants

A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-12-13
Completion: 2026-06-09
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
No Results Yet
NCT05473598 | ACTIVE_NOT_RECRUITING | NA
234 Participants

Stand Down-Think Before You Drink: An RCT of a Mobile App for Hazardous Drinking With Peer Phone Support

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-12-01
Completion: 2025-12-01
Conditions
Alcoholism
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT05466929 | COMPLETED | NA
365 Participants

Engagement With Digital Mental Health (DMH) Technologies in Pediatric Primary Care

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2024-07-16
Completion: 2025-11-06
Conditions
Mental Health
Interventions
BEHAVIORAL
No Results Yet
NCT05458219 | RECRUITING | PHASE1
470 Participants

A First-in-human Study of IBI343 in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-26
Completion: 2027-06-30
Conditions
Locally Advanced Unresectable or Metastatic Solid Tumors
Interventions
DRUG
No Results Yet
NCT05455320 | ACTIVE_NOT_RECRUITING | PHASE3
864 Participants
NCT05453903 | RECRUITING | PHASE1
200 Participants

A Study of Bleximenib in Combination With Acute Myeloid Leukemia (AML) Directed Therapies

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-04
Completion: 2026-10-30
Conditions
Leukemia, Myeloid, Acute
Interventions
DRUG
No Results Yet
NCT05452642 | ACTIVE_NOT_RECRUITING | NA
223 Participants

The Supporting Understanding of PCOS Education and Research (SUPER) Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-08-15
Completion: 2026-07-15
Conditions
Polycystic Ovary
Interventions
BEHAVIORAL
No Results Yet
NCT05451212 | COMPLETED | PHASE1
7 Participants

Open-label Study to Evaluate the Safety of Various Dosing Regimens of MuSK-CAART for MuSK Myasthenia Gravis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-11-23
Completion: 2025-07-24
Conditions
MuSK Myasthenia Gravis
Interventions
BIOLOGICAL
No Results Yet
NCT05438212 | ACTIVE_NOT_RECRUITING | PHASE3
237 Participants

Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-24
Completion: 2027-03-16
Conditions
Metastatic Malignant Neoplasm in the Brain
Interventions
PROCEDURE OTHER RADIATION
No Results Yet
NCT05438043 | RECRUITING | PHASE3
500 Participants

A Study of Daratumumab

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-12-15
Completion: 2026-01-30
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05437562 | NOT_YET_RECRUITING | PHASE2
120 Participants

Randomized Clinical Trial for Ewing Amputation in the VA

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2025-12-01
Completion: 2030-12-01
Conditions
Peripheral Arterial Disease
Interventions
PROCEDURE
No Results Yet
NCT05434234 | RECRUITING | PHASE1/PHASE2
312 Participants

A Study of YL201 in Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-05-25
Completion: 2027-04-06
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT05425264 | RECRUITING | NA
80 Participants

Home-Based Exercise Tele-Rehabilitation After COVID-19

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2023-06-29
Completion: 2027-01-30
Conditions
Post SARS-CoV2 (COVID-19)
Interventions
OTHER
No Results Yet
NCT05424822 | ACTIVE_NOT_RECRUITING | PHASE1
167 Participants

A Study of JNJ-80948543, a T-cell Redirecting CD79b x CD20 x CD3 Trispecific Antibody, in Participants With Non-Hodgkin Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-08-18
Completion: 2026-06-12
Conditions
Lymphoma, Non-Hodgkin Leukemia, Lymphocytic, Chronic, B-Cell
Interventions
DRUG
No Results Yet
NCT05421663 | RECRUITING | PHASE1/PHASE2
385 Participants

A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-08-12
Completion: 2028-12-29
Conditions
Lymphoma, Non-Hodgkin Lymphoma, B-Cell Lymphoma, Large B-Cell, Diffuse
Interventions
BIOLOGICAL
No Results Yet
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