Clinical Trials

NCT04065399 | RECRUITING | PHASE1/PHASE2

413 Participants

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-11-05

Completion: 2027-12-15

Conditions

Acute Myeloid Leukemia Acute Lymphoblastic Leukemia Mixed Lineage Acute Leukemia Mixed Phenotype Acute Leukemia Acute Leukemia of Ambiguous Lineage

Interventions

DRUG

No Results Yet

NCT04054154 | ACTIVE_NOT_RECRUITING | NA

27 Participants

An Investigational Device (Millar Mikro-Tip Catheter) and Imaging Scan (Shear Wave Elastography) in Measuring Tumor Pressure and Stiffness in Patients With Solid Tumors Undergoing Ultrasound-Guided Biopsy

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2015-12-29

Completion: 2026-12-31

Conditions

Solid Neoplasm

Interventions

DEVICE PROCEDURE

No Results Yet

NCT04009499 | ACTIVE_NOT_RECRUITING | PHASE3

1131 Participants

A Study to Assess the Long-term Safety, Tolerability, and Efficacy of Bimekizumab in the Treatment of Subjects With Active Psoriatic Arthritis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-08-13

Completion: 2026-05-25

Conditions

Psoriatic Arthritis

Interventions

DRUG

No Results Yet

NCT03991962 | RECRUITING | PHASE2

28 Participants

Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-09-19

Completion: 2026-08-31

Conditions

Pancreatic Cancer

Interventions

DRUG RADIATION

No Results Yet

NCT03981055 | ACTIVE_NOT_RECRUITING | NA

40 Participants

Parkinson's Disease: Enhancing Physical Therapy With Brain Stimulation for Treating Postural Instability.

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2020-01-23

Completion: 2024-04-30

Conditions

Parkinson Disease

Interventions

DEVICE OTHER

Results Available

NCT03975231 | RECRUITING | PHASE1

6 Participants

Dabrafenib, Trametinib, and IMRT in Treating Patients With BRAF Mutated Anaplastic Thyroid Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2020-09-14

Completion: 2026-02-28

Conditions

BRAF NP_004324.2:p.V600E BRAF V600K Mutation Present Thyroid Gland Anaplastic Carcinoma

Interventions

DRUG RADIATION

No Results Yet

NCT03955627 | COMPLETED | NA

12 Participants

REJOIN Trial for Older Breast Cancer Survivors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-06-15

Completion: 2025-07-29

Conditions

Breast Cancer Female

Interventions

BEHAVIORAL

No Results Yet

NCT03941756 | RECRUITING | NA

252 Participants

Lymphovenous Bypass Procedure Before Underarm Lymph Node Surgery in Preventing Lymphedema in Patients With Inflammatory or Locally Advanced Non-inflammatory Breast Cancer or Melanoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-08-14

Completion: 2025-12-31

Conditions

Anatomic Stage III Breast Cancer AJCC v8 Breast Inflammatory Carcinoma Locally Advanced Breast Carcinoma Melanoma

Interventions

DRUG PROCEDURE

No Results Yet

NCT03933631 | RECRUITING | PHASE3

142 Participants

Pilocarpine Use After Kahook Goniotomy

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-05-01

Completion: 2028-06-30

Conditions

Glaucoma

Interventions

DRUG

No Results Yet

NCT03922724 | RECRUITING | PHASE2

330 Participants

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-04-18

Completion: 2026-10-31

Conditions

Peripheral T-cell Lymphomas Lymphoproliferative Disorders Immune System Diseases

Interventions

DRUG PROCEDURE

No Results Yet

NCT03920774 | RECRUITING

400 Participants

The Natural History of Familial Dysautonomia

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2017-02-22

Completion: 2027-02-21

Conditions

Familial Dysautonomia (Riley-Day Syndrome) Hereditary Sensory and Autonomic Neuropathies Hereditary Sensory and Autonomic Neuropathy 3

No Results Yet

NCT03909178 | ACTIVE_NOT_RECRUITING | NA

110 Participants

Arthroscopic Labral Repair Versus Physical Therapy for Tears of the Acetabular Labrum

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2013-10-21

Completion: 2020-06-20

Conditions

Acetabular Labrum Tear Femoro Acetabular Impingement Hip Arthroscopy Physical Therapy Osteoarthritis, Hip

Interventions

PROCEDURE

Results Available

NCT03891953 | ACTIVE_NOT_RECRUITING | PHASE1

98 Participants

Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-05-07

Completion: 2026-03-30

Conditions

Carcinoma, Non-Small-Cell Lung Melanoma Nasopharyngeal Carcinoma Microsatellite Stable Colorectal Cancer Triple Negative Breast Cancer

Interventions

DRUG

No Results Yet

NCT03887715 | RECRUITING | NA

6800 Participants

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-09-26

Completion: 2028-02-28

Conditions

Treatment Resistant Depression

Interventions

DEVICE

No Results Yet

NCT03872401 | COMPLETED | PHASE3

12301 Participants

Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-06-11

Completion: 2025-07-25

Conditions

Coronary Heart Disease (CHD)

Interventions

DRUG

No Results Yet

NCT03869190 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

272 Participants

Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-06-01

Completion: 2025-10-08

Conditions

Urothelial Carcinoma Bladder Cancer

Interventions

DRUG

No Results Yet

NCT03865992 | ACTIVE_NOT_RECRUITING | NA

42 Participants

Curcumin in Reducing Joint Pain in Breast Cancer Survivors With Aromatase Inhibitor-Induced Joint Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-03-04

Completion: 2026-09-08

Conditions

Breast Cancer Joint Pain

Interventions

DIETARY_SUPPLEMENT OTHER BEHAVIORAL

No Results Yet

NCT03851302 | COMPLETED | NA

21 Participants

Effects of Remote Ischemic Conditioning on Hand Use in Individuals With SCI and ALS

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-10-28

Completion: 2022-07-30

Conditions

Spinal Cord Injuries Amyotrophic Lateral Sclerosis

Interventions

OTHER

Results Available

NCT03833154 | ACTIVE_NOT_RECRUITING | PHASE3

724 Participants

Durvalumab With Stereotactic Body Radiation Therapy (SBRT) vs Placebo With SBRT in Early Stage Unresected Non-small Cell Lung Cancer (NSCLC) Patients/ Osimertinib Following SBRT in Patients With Early Stage Unresected NSCLC Harboring an EGFR Mutation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-03-06

Completion: 2027-04-16

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG OTHER

No Results Yet

NCT03813407 | RECRUITING | PHASE3

140 Participants

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-04-02

Completion: 2026-06-29

Conditions

Hyperkalaemia

Interventions

DRUG

No Results Yet

NCT03803774 | ACTIVE_NOT_RECRUITING | PHASE1

13 Participants

Birinapant and Intensity Modulated Re-Irradiation Therapy in Treating Patients With Locally Recurrent Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-09-25

Completion: 2023-11-15

Conditions

Locally Recurrent Head and Neck Squamous Cell Carcinoma Nasopharyngeal Squamous Cell Carcinoma Sinonasal Squamous Cell Carcinoma

Interventions

PROCEDURE DRUG RADIATION

Results Available

NCT03803423 | RECRUITING | NA

1000 Participants

Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-11-27

Completion: 2026-11-27

Conditions

End Stage Renal Disease End Stage Liver Disease

Interventions

OTHER

No Results Yet

NCT03801876 | RECRUITING | PHASE3

300 Participants

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-06-26

Completion: 2026-12-21

Conditions

Clinical Stage I Esophageal Adenocarcinoma AJCC v8 Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8 Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8 Clinical Stage II Esophageal Adenocarcinoma AJCC v8 Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8 Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8 Clinical Stage III Esophageal Adenocarcinoma AJCC v8 Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8 Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8 Clinical Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8 Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8 Thoracic Esophagus Squamous Cell Carcinoma

Interventions

PROCEDURE DRUG RADIATION OTHER

No Results Yet

NCT03778827 | RECRUITING | NA

44 Participants

A Center Based Study of Pivotal Response Treatment for Preschoolers With Autism

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-05-13

Completion: 2026-12-31

Conditions

Autism Spectrum Disorder Autism

Interventions

BEHAVIORAL

No Results Yet

NCT03767244 | ACTIVE_NOT_RECRUITING | PHASE3

2517 Participants

A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-06-11

Completion: 2026-02-10

Conditions

Prostatic Neoplasms

Interventions

DRUG

No Results Yet

NCT03767231 | NOT_YET_RECRUITING | NA

200 Participants

ED Patient's Perceptions and Acceptability Toward a Novel POC HCV Viral Load Testing

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2026-11-30

Completion: 2027-11-30

Conditions

Hepatitis C

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03762590 | ACTIVE_NOT_RECRUITING | NA

1000 Participants

GENetic Education Risk Assessment and TEsting Study

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-05-08

Completion: 2022-12-12

Conditions

Candidates for Hereditary Pancreatic Cancer Testing

Interventions

OTHER

No Results Yet

NCT03747757 | ACTIVE_NOT_RECRUITING | PHASE2

48 Participants

Cognitive Behavioral Therapy in Helping Patients With Acute Myeloid Leukemia or Lymphoma With Cancer-Related Fatigue

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-11-29

Completion: 2027-09-11

Conditions

Acute Myeloid Leukemia Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome Cancer Fatigue Lymphoma Secondary Acute Myeloid Leukemia

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT03729453 | ACTIVE_NOT_RECRUITING

100 Participants

Intra-operative Pancreatoscopy in Patients With IPMN

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2019-03-20

Completion: 2022-08-11

Conditions

Intraductal Papillary Mucinous Neoplasm

Interventions

DEVICE

No Results Yet

NCT03706690 | ACTIVE_NOT_RECRUITING | PHASE3

407 Participants

A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-11-27

Completion: 2024-06-23

Conditions

Carcinoma, Non-Small-Cell Lung

Interventions

DRUG OTHER

Results Available

NCT03695978 | RECRUITING

200 Participants

Efficacy, Safety & Utilisation of Nuwiq, Octanate and Wilate in Previously Untreated & Minimally Treated Haemophilia A Patients

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2018-02-13

Completion: 2030-06-30

Conditions

Haemophilia A

No Results Yet

NCT03694756 | RECRUITING | NA

95 Participants

TMEM-MRI: A Pilot Feasibility Study of MRI for Imaging of TMEM in Patients With Operable Breast Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-12-12

Completion: 2026-12-31

Conditions

Breast Cancer

Interventions

DEVICE PROCEDURE

No Results Yet

NCT03678441 | ACTIVE_NOT_RECRUITING | NA

100 Participants

Electronic Neurocognitive Tools in Screening for Mental Capability in Patients Undergoing Liver Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-08-17

Completion: 2027-04-30

Conditions

Liver and Intrahepatic Bile Duct Disorder

Interventions

BEHAVIORAL PROCEDURE

No Results Yet

NCT03674047 | ACTIVE_NOT_RECRUITING | PHASE2

50 Participants

Ruxolitinib for Bronchiolitis Obliterans Syndrome (BOS) After Allogeneic Hematopoietic Cell Transplantation (HCT)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-04-19

Completion: 2022-12-02

Conditions

Other Cancer

Interventions

DRUG

No Results Yet

NCT03672773 | ACTIVE_NOT_RECRUITING | PHASE2

35 Participants

Talazoparib and Low-Dose Temozolomide in Treating Participants With Relapsed or Refractory Extensive-Stage Small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-10-31

Completion: 2026-10-01

Conditions

Recurrent Extensive Stage Small Cell Lung Carcinoma Refractory Extensive Stage Small Cell Lung Carcinoma

Interventions

DRUG

No Results Yet

NCT03672539 | ACTIVE_NOT_RECRUITING | PHASE2

50 Participants

Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-11-07

Completion: 2027-11-30

Conditions

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome Chronic Myelomonocytic Leukemia High Risk Myelodysplastic Syndrome Myelodysplastic Syndrome Recurrent Acute Myeloid Leukemia Refractory Acute Myeloid Leukemia

Interventions

DRUG OTHER

No Results Yet

NCT03657394 | ACTIVE_NOT_RECRUITING | NA

3442 Participants

Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-10-17

Completion: 2025-09-01

Conditions

Hypoxic-Ischemic Encephalopathy Birth Asphyxia

Interventions

OTHER

No Results Yet

NCT03653637 | COMPLETED | NA

294 Participants

Group ("Project Life Force") vs. Individual Suicide Safety Planning RCT

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-10-15

Completion: 2023-12-31

Conditions

Suicide

Interventions

BEHAVIORAL

Results Available

NCT03652064 | ACTIVE_NOT_RECRUITING | PHASE3

395 Participants

A Study Comparing Daratumumab, VELCADE (Bortezomib), Lenalidomide, and Dexamethasone (D-VRd) With VELCADE, Lenalidomide, and Dexamethasone (VRd) in Participants With Untreated Multiple Myeloma and for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-11-06

Completion: 2024-05-07

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT03650114 | ACTIVE_NOT_RECRUITING | PHASE3

1882 Participants

Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-12-28

Completion: 2027-12-30

Conditions

Relapsing Multiple Sclerosis

Interventions

BIOLOGICAL

No Results Yet