Clinical Trials

NCT03672539 | ACTIVE_NOT_RECRUITING | PHASE2

50 Participants

Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-11-07

Completion: 2027-11-30

Conditions

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome Chronic Myelomonocytic Leukemia High Risk Myelodysplastic Syndrome Myelodysplastic Syndrome Recurrent Acute Myeloid Leukemia Refractory Acute Myeloid Leukemia

Interventions

DRUG OTHER

No Results Yet

NCT03657394 | ACTIVE_NOT_RECRUITING | NA

3442 Participants

Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2022-10-17

Completion: 2025-09-01

Conditions

Hypoxic-Ischemic Encephalopathy Birth Asphyxia

Interventions

OTHER

No Results Yet

NCT03653637 | COMPLETED | NA

294 Participants

Group ("Project Life Force") vs. Individual Suicide Safety Planning RCT

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-10-15

Completion: 2023-12-31

Conditions

Suicide

Interventions

BEHAVIORAL

Results Available

NCT03652064 | ACTIVE_NOT_RECRUITING | PHASE3

395 Participants

A Study Comparing Daratumumab, VELCADE (Bortezomib), Lenalidomide, and Dexamethasone (D-VRd) With VELCADE, Lenalidomide, and Dexamethasone (VRd) in Participants With Untreated Multiple Myeloma and for Whom Hematopoietic Stem Cell Transplant is Not Planned as Initial Therapy

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-11-06

Completion: 2024-05-07

Conditions

Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT03650114 | ACTIVE_NOT_RECRUITING | PHASE3

1882 Participants

Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-12-28

Completion: 2027-12-30

Conditions

Relapsing Multiple Sclerosis

Interventions

BIOLOGICAL

No Results Yet

NCT03617939 | RECRUITING

20000 Participants

A Lifetime Partnership With Patients Who Have or May be at Risk of Having Cancer

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2015-09-16

Completion: 2035-09-30

Conditions

Cancer Risk

Interventions

PROCEDURE OTHER

No Results Yet

NCT03616483 | RECRUITING

2500 Participants

The Indiana Myeloma Registry

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2018-06-18

Completion: 2028-06-30

Conditions

Plasma Cell Dyscrasias

Interventions

OTHER

No Results Yet

NCT03583684 | RECRUITING | NA

36 Participants

Neuroimaging Predictors of Improvement to Pivotal Response Treatment (PRT) in Young Children With Autism

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-12-07

Completion: 2026-11-30

Conditions

Autism Spectrum Disorder Autism

Interventions

BEHAVIORAL

No Results Yet

NCT03578367 | COMPLETED | PHASE2

104 Participants

Study of Efficacy and Safety of Asciminib in Combination With Imatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-11-22

Completion: 2021-11-08

Conditions

CML Chronic Myelogenous Leukemia Leukemia, Myeloid Chronic Hematologic Diseases

Interventions

DRUG

Results Available

NCT03565783 | ACTIVE_NOT_RECRUITING | PHASE2

44 Participants

Cemiplimab in Treating Patients With Recurrent and Resectable Stage II-IV Head and Neck Cutaneous Squamous Cell Cancer Before Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-07-03

Completion: 2025-12-31

Conditions

Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck Stage II Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8

Interventions

BIOLOGICAL

No Results Yet

NCT03527537 | RECRUITING | PHASE4

416 Participants

Gestational Diabetes and Pharmacotherapy (GAP)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2021-05-04

Completion: 2026-03-31

Conditions

Gestational Diabetes

Interventions

DRUG

No Results Yet

NCT03527277 | COMPLETED | NA

56 Participants

Orange Juice And Sugar Intervention Study

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-06-01

Completion: 2023-05-28

Conditions

Cardiovascular Risk Factor Type2 Diabetes Mellitus Insulin Sensitivity Metabolic Syndrome

Interventions

OTHER

Results Available

NCT03520647 | RECRUITING | PHASE2

56 Participants

Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-02-19

Completion: 2026-06-01

Conditions

Severe Aplastic Anemia (SAA) Hypo-Plastic Myelodysplastic Syndrome (MDS) Paroxysmal Nocturnal Hemoglobinuria (PNH)

Interventions

DRUG OTHER

No Results Yet

NCT03494569 | RECRUITING | PHASE1

36 Participants

Total Marrow and Lymphoid Irradiation, Fludarabine, and Melphalan Before Donor Stem Cell Transplant in Treating Participants With High-Risk Acute Leukemia or Myelodysplastic Syndrome

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-07-06

Completion: 2026-09-08

Conditions

Acute Lymphoblastic Leukemia Acute Lymphoblastic Leukemia in Remission Acute Myeloid Leukemia Acute Myeloid Leukemia in Remission Hematopoietic Cell Transplantation Recipient Minimal Residual Disease Myelodysplastic Syndrome Secondary Acute Myeloid Leukemia

Interventions

DRUG OTHER RADIATION

No Results Yet

NCT03491176 | ACTIVE_NOT_RECRUITING

100 Participants

Magnetic Resonance (MR) Imaging & Blood Biomarkers for Head and Neck Cancer

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2017-05-18

Completion: 2027-10-31

Conditions

Cutaneous Squamous Cell Carcinoma of the Head and Neck Healthy Subject Head and Neck Cancer

Interventions

PROCEDURE OTHER

No Results Yet

NCT03486873 | RECRUITING | PHASE3

3500 Participants

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-08-21

Completion: 2043-08-04

Conditions

Solid Tumors Hematologic Malignancies

Interventions

DRUG BIOLOGICAL

No Results Yet

NCT03481205 | RECRUITING | NA

10 Participants

Ischemic Conditioning During Air tRansport Save penUmbral Tissue

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2020-06-01

Completion: 2026-12-01

Conditions

Acute Stroke

Interventions

DEVICE

No Results Yet

NCT03468426 | COMPLETED | PHASE1

252 Participants

A Study to Test Different Doses of BI 836880 Combined With Ezabenlimab in Patients With Advanced Non-small Cell Lung Cancer Followed by Other Types of Advanced Solid Tumours

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-07-05

Completion: 2024-07-31

Conditions

Non-squamous, Non-Small-Cell Lung Cancer Neoplasms

Interventions

DRUG

Results Available

NCT03430037 | ENROLLING_BY_INVITATION | PHASE2

40 Participants

Alleviation by Fisetin of Frailty, Inflammation, and Related Measures in Older Women

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-02-06

Completion: 2026-04-30

Conditions

Frail Elderly Syndrome

Interventions

DIETARY_SUPPLEMENT DRUG

No Results Yet

NCT03423628 | RECRUITING | PHASE1

180 Participants

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-04-02

Completion: 2026-09-16

Conditions

Recurrent Glioblastoma Multiforme Primary Glioblastoma Multiforme Brain Neoplasms, Malignant Leptomeningeal Disease (LMD)

Interventions

DRUG RADIATION

No Results Yet

NCT03399799 | ACTIVE_NOT_RECRUITING | PHASE1

279 Participants

Dose Escalation Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-12-16

Completion: 2022-07-07

Conditions

Hematological Malignancies

Interventions

DRUG

No Results Yet

NCT03393884 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

130 Participants

Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-09-05

Completion: 2024-07-25

Conditions

Epithelial Ovarian Cancer Fallopian Tube Cancer Primary Peritoneal Cancer

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT03391869 | ACTIVE_NOT_RECRUITING | PHASE3

339 Participants

Nivolumab and Ipilimumab With or Without Local Consolidation Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-12-29

Completion: 2025-12-31

Conditions

Lung Adenocarcinoma Lung Non-Small Cell Carcinoma Stage IV Lung Cancer AJCC v8

Interventions

BIOLOGICAL PROCEDURE OTHER RADIATION

No Results Yet

NCT03375619 | RECRUITING

500 Participants

Long-term Follow-up Study of Patients Receiving CAR-T Cells

Study Type: OBSERVATIONAL

Last Updated: 2025-11-10

Start Date: 2017-12-01

Completion: 2035-01-01

Conditions

Chronic Lymphocytic Leukemia Lymphomas Non-Hodgkin's B-Cell Lymphoma, Small Lymphocytic Mantle Cell Lymphoma Central Nervous System Lymphoma Diffuse Large B Cell Lymphoma Follicular Lymphoma Burkitt Lymphoma Multiple Myeloma

Interventions

OTHER

No Results Yet

NCT03371719 | ACTIVE_NOT_RECRUITING | PHASE2

324 Participants

Radiation Therapy With or Without Apalutamide in Treating Patients With Recurrent Prostate Cancer, the BALANCE Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-06-20

Completion: 2025-03-10

Conditions

Recurrent Prostate Carcinoma Stage III Prostate Adenocarcinoma AJCC v7 Stage IV Prostate Adenocarcinoma AJCC v7

Interventions

DRUG RADIATION OTHER

No Results Yet

NCT03340506 | RECRUITING | PHASE4

100 Participants

Dabrafenib and/or Trametinib Rollover Study

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-12-28

Completion: 2029-12-18

Conditions

Melanoma Non Small Cell Lung Cancer Solid Tumor Rare Cancers High Grade Glioma

Interventions

DRUG

No Results Yet

NCT03301220 | ACTIVE_NOT_RECRUITING | PHASE3

390 Participants

A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-11-07

Completion: 2024-05-01

Conditions

Smoldering Multiple Myeloma

Interventions

DRUG

No Results Yet

NCT03288545 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

348 Participants

A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-10-11

Completion: 2026-05-11

Conditions

Carcinoma, Transitional Cell Urinary Bladder Neoplasms Urologic Neoplasms Renal Pelvis Neoplasms Urothelial Cancer Ureteral Neoplasms Urethral Neoplasms

Interventions

DRUG

No Results Yet

NCT03281889 | ACTIVE_NOT_RECRUITING | NA

20 Participants

Proton Craniospinal Irradiation With Bone Sparing to Decrease Growth Decrement From Radiation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-01-04

Completion: 2027-06-30

Conditions

Brain Tumor

Interventions

RADIATION

No Results Yet

NCT03280563 | COMPLETED | PHASE1/PHASE2

144 Participants

A Study of Multiple Immunotherapy-Based Treatment Combinations in Hormone Receptor (HR)-Positive Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-12-22

Completion: 2024-09-26

Conditions

Breast Neoplasms

Interventions

DRUG

Results Available

NCT03263572 | RECRUITING | PHASE2

90 Participants

Blinatumomab, Methotrexate, Cytarabine, and Ponatinib in Treating Patients With Philadelphia Chromosome-Positive, or BCR-ABL Positive, or Relapsed/Refractory, Acute Lymphoblastic Leukemia

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-11-29

Completion: 2027-11-30

Conditions

Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive Acute Lymphoblastic Leukemia BCR-ABL1 Fusion Protein Expression Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive Philadelphia Chromosome Positive Recurrent Acute Lymphoblastic Leukemia Refractory Acute Lymphoblastic Leukemia t(9;22)

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT03259503 | COMPLETED | PHASE1

50 Participants

Olaparib and High-Dose Chemotherapy in Treating Patients With Relapsed or Refractory Lymphomas Undergoing Stem Cell Transplant

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2019-09-13

Completion: 2025-11-05

Conditions

Recurrent Diffuse Large B-Cell Lymphoma Recurrent T-Cell Non-Hodgkin Lymphoma Refractory Diffuse Large B-Cell Lymphoma Refractory Hodgkin Lymphoma Refractory T-Cell Non-Hodgkin Lymphoma

Interventions

DRUG PROCEDURE OTHER BIOLOGICAL

No Results Yet

NCT03228537 | ACTIVE_NOT_RECRUITING | PHASE1

28 Participants

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-07-16

Completion: 2022-10-01

Conditions

Biphasic Mesothelioma Epithelioid Mesothelioma Stage I Pleural Malignant Mesothelioma AJCC v7 Stage IA Pleural Malignant Mesothelioma AJCC v7 Stage IB Pleural Malignant Mesothelioma AJCC v7 Stage II Pleural Malignant Mesothelioma AJCC v7 Stage III Pleural Malignant Mesothelioma AJCC v7

Interventions

DRUG PROCEDURE RADIATION

Results Available

NCT03203525 | RECRUITING | PHASE1

52 Participants

Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2020-06-23

Completion: 2026-12-31

Conditions

Advanced Malignant Neoplasm Colorectal Carcinoma Metastatic in the Liver Metastatic Malignant Neoplasm in the Liver Refractory Malignant Neoplasm

Interventions

BIOLOGICAL DRUG PROCEDURE

No Results Yet

NCT03187951 | ACTIVE_NOT_RECRUITING | NA

152 Participants

PancFit: Multimodal Exercise During Preoperative Therapy for Pancreatic Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-06-13

Completion: 2022-12-31

Conditions

Other Disorders of Glucose Regulation and Pancreatic Internal Secretion Pancreatic Cancer

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT03186898 | RECRUITING | PHASE3

186 Participants

Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2018-01-26

Completion: 2027-06-30

Conditions

Recurrent Hepatocellular Carcinoma Stage III Hepatocellular Carcinoma AJCC v7 Unresectable Hepatocellular Carcinoma

Interventions

PROCEDURE OTHER RADIATION

No Results Yet

NCT03180268 | RECRUITING | PHASE3

163 Participants

Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-09-12

Completion: 2027-06-15

Conditions

Grade 2 Meningioma Intracranial Meningioma

Interventions

PROCEDURE OTHER RADIATION

No Results Yet

NCT03173248 | ACTIVE_NOT_RECRUITING | PHASE3

146 Participants

Study of AG-120 (Ivosidenib) vs. Placebo in Combination With Azacitidine in Participants With Previously Untreated Acute Myeloid Leukemia With an IDH1 Mutation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-06-26

Completion: 2021-03-18

Conditions

Newly Diagnosed Acute Myeloid Leukemia (AML) Untreated AML AML Arising From Myelodysplastic Syndrome (MDS) Leukemia, Myeloid, Acute

Interventions

DRUG

Results Available

NCT03160079 | COMPLETED | PHASE1/PHASE2

16 Participants

Blinatumomab & Pembrolizumab for Adults With Relapsed/Refractory B-cell ALL With High Marrow Lymphoblasts

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-08-04

Completion: 2021-12-21

Conditions

B-Cell Acute Lymphoblastic Leukemia, Adult

Interventions

DRUG

Results Available

NCT03153475 | ACTIVE_NOT_RECRUITING | NA

400 Participants

ATTUNE Revision System in the Revision Total Knee Arthroplasty Population

Study Type: INTERVENTIONAL

Last Updated: 2025-11-10

Start Date: 2017-05-30

Completion: 2029-03-31

Conditions

Revision Total Knee Arthroplasty

Interventions

DEVICE

No Results Yet