Clinical Trials

NCT03933631 | RECRUITING | PHASE3
142 Participants

Pilocarpine Use After Kahook Goniotomy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-05-01
Completion: 2028-06-30
Conditions
Glaucoma
Interventions
DRUG
No Results Yet
NCT03922724 | RECRUITING | PHASE2
330 Participants

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-04-18
Completion: 2026-10-31
Conditions
Peripheral T-cell Lymphomas Lymphoproliferative Disorders Immune System Diseases
Interventions
DRUG PROCEDURE
No Results Yet
NCT03920774 | RECRUITING
400 Participants

The Natural History of Familial Dysautonomia

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2017-02-22
Completion: 2027-02-21
Conditions
Familial Dysautonomia (Riley-Day Syndrome) Hereditary Sensory and Autonomic Neuropathies Hereditary Sensory and Autonomic Neuropathy 3
No Results Yet
NCT03909178 | ACTIVE_NOT_RECRUITING | NA
110 Participants

Arthroscopic Labral Repair Versus Physical Therapy for Tears of the Acetabular Labrum

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2013-10-21
Completion: 2020-06-20
Conditions
Acetabular Labrum Tear Femoro Acetabular Impingement Hip Arthroscopy Physical Therapy Osteoarthritis, Hip
Interventions
PROCEDURE
NCT03891953 | ACTIVE_NOT_RECRUITING | PHASE1
98 Participants

Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-05-07
Completion: 2026-03-30
Conditions
Carcinoma, Non-Small-Cell Lung Melanoma Nasopharyngeal Carcinoma Microsatellite Stable Colorectal Cancer Triple Negative Breast Cancer
Interventions
DRUG
No Results Yet
NCT03887715 | RECRUITING | NA
6800 Participants

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-09-26
Completion: 2028-02-28
Conditions
Treatment Resistant Depression
Interventions
DEVICE
No Results Yet
NCT03872401 | COMPLETED | PHASE3
12301 Participants

Effect of Evolocumab in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-06-11
Completion: 2025-07-25
Conditions
Coronary Heart Disease (CHD)
Interventions
DRUG
No Results Yet
NCT03869190 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
272 Participants

Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-06-01
Completion: 2025-10-08
Conditions
Urothelial Carcinoma Bladder Cancer
Interventions
DRUG
No Results Yet
NCT03865992 | ACTIVE_NOT_RECRUITING | NA
42 Participants

Curcumin in Reducing Joint Pain in Breast Cancer Survivors With Aromatase Inhibitor-Induced Joint Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-03-04
Completion: 2026-09-08
Conditions
Breast Cancer Joint Pain
Interventions
DIETARY_SUPPLEMENT OTHER BEHAVIORAL
No Results Yet
NCT03851302 | COMPLETED | NA
21 Participants

Effects of Remote Ischemic Conditioning on Hand Use in Individuals With SCI and ALS

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-10-28
Completion: 2022-07-30
Conditions
Spinal Cord Injuries Amyotrophic Lateral Sclerosis
Interventions
OTHER
NCT03833154 | ACTIVE_NOT_RECRUITING | PHASE3
724 Participants

Durvalumab With Stereotactic Body Radiation Therapy (SBRT) vs Placebo With SBRT in Early Stage Unresected Non-small Cell Lung Cancer (NSCLC) Patients/ Osimertinib Following SBRT in Patients With Early Stage Unresected NSCLC Harboring an EGFR Mutation

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-03-06
Completion: 2027-04-16
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG OTHER
No Results Yet
NCT03813407 | RECRUITING | PHASE3
140 Participants

An Open-label Study to Assess Safety and Efficacy of SZC in Paediatric Patients With Hyperkalaemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-04-02
Completion: 2026-06-29
Conditions
Hyperkalaemia
Interventions
DRUG
No Results Yet
NCT03803774 | ACTIVE_NOT_RECRUITING | PHASE1
13 Participants

Birinapant and Intensity Modulated Re-Irradiation Therapy in Treating Patients With Locally Recurrent Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-09-25
Completion: 2023-11-15
Conditions
Locally Recurrent Head and Neck Squamous Cell Carcinoma Nasopharyngeal Squamous Cell Carcinoma Sinonasal Squamous Cell Carcinoma
Interventions
PROCEDURE DRUG RADIATION
NCT03803423 | RECRUITING | NA
1000 Participants

Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2017-11-27
Completion: 2026-11-27
Conditions
End Stage Renal Disease End Stage Liver Disease
Interventions
OTHER
No Results Yet
NCT03801876 | RECRUITING | PHASE3
300 Participants

Comparing Proton Therapy to Photon Radiation Therapy for Esophageal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-06-26
Completion: 2026-12-21
Conditions
Clinical Stage I Esophageal Adenocarcinoma AJCC v8 Clinical Stage I Esophageal Squamous Cell Carcinoma AJCC v8 Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8 Clinical Stage II Esophageal Adenocarcinoma AJCC v8 Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8 Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8 Clinical Stage III Esophageal Adenocarcinoma AJCC v8 Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8 Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8 Clinical Stage IVA Esophageal Squamous Cell Carcinoma AJCC v8 Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8 Thoracic Esophagus Squamous Cell Carcinoma
Interventions
PROCEDURE DRUG RADIATION OTHER
No Results Yet
NCT03778827 | RECRUITING | NA
44 Participants

A Center Based Study of Pivotal Response Treatment for Preschoolers With Autism

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-05-13
Completion: 2026-12-31
Conditions
Autism Spectrum Disorder Autism
Interventions
BEHAVIORAL
No Results Yet
NCT03767244 | ACTIVE_NOT_RECRUITING | PHASE3
2517 Participants

A Study of Apalutamide in Participants With High-Risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-06-11
Completion: 2026-02-10
Conditions
Prostatic Neoplasms
Interventions
DRUG
No Results Yet
NCT03767231 | NOT_YET_RECRUITING | NA
200 Participants

ED Patient's Perceptions and Acceptability Toward a Novel POC HCV Viral Load Testing

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2026-11-30
Completion: 2027-11-30
Conditions
Hepatitis C
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03762590 | ACTIVE_NOT_RECRUITING | NA
1000 Participants

GENetic Education Risk Assessment and TEsting Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-05-08
Completion: 2022-12-12
Conditions
Candidates for Hereditary Pancreatic Cancer Testing
Interventions
OTHER
No Results Yet
NCT03747757 | ACTIVE_NOT_RECRUITING | PHASE2
48 Participants

Cognitive Behavioral Therapy in Helping Patients With Acute Myeloid Leukemia or Lymphoma With Cancer-Related Fatigue

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2018-11-29
Completion: 2027-09-11
Conditions
Acute Myeloid Leukemia Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome Cancer Fatigue Lymphoma Secondary Acute Myeloid Leukemia
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT03729453 | ACTIVE_NOT_RECRUITING
100 Participants

Intra-operative Pancreatoscopy in Patients With IPMN

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2019-03-20
Completion: 2022-08-11
Conditions
Intraductal Papillary Mucinous Neoplasm
Interventions
DEVICE
No Results Yet
NCT03706690 | ACTIVE_NOT_RECRUITING | PHASE3
407 Participants

A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2018-11-27
Completion: 2024-06-23
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG OTHER
NCT03695978 | RECRUITING
200 Participants

Efficacy, Safety & Utilisation of Nuwiq, Octanate and Wilate in Previously Untreated & Minimally Treated Haemophilia A Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2018-02-13
Completion: 2030-06-30
Conditions
Haemophilia A
No Results Yet
NCT03694756 | RECRUITING | NA
95 Participants

TMEM-MRI: A Pilot Feasibility Study of MRI for Imaging of TMEM in Patients With Operable Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2018-12-12
Completion: 2026-12-31
Conditions
Breast Cancer
Interventions
DEVICE PROCEDURE
No Results Yet
NCT03678441 | ACTIVE_NOT_RECRUITING | NA
100 Participants

Electronic Neurocognitive Tools in Screening for Mental Capability in Patients Undergoing Liver Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2018-08-17
Completion: 2027-04-30
Conditions
Liver and Intrahepatic Bile Duct Disorder
Interventions
BEHAVIORAL PROCEDURE
No Results Yet
NCT03674047 | ACTIVE_NOT_RECRUITING | PHASE2
50 Participants

Ruxolitinib for Bronchiolitis Obliterans Syndrome (BOS) After Allogeneic Hematopoietic Cell Transplantation (HCT)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-04-19
Completion: 2022-12-02
Conditions
Other Cancer
Interventions
DRUG
No Results Yet
NCT03672773 | ACTIVE_NOT_RECRUITING | PHASE2
35 Participants

Talazoparib and Low-Dose Temozolomide in Treating Participants With Relapsed or Refractory Extensive-Stage Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2018-10-31
Completion: 2026-10-01
Conditions
Recurrent Extensive Stage Small Cell Lung Carcinoma Refractory Extensive Stage Small Cell Lung Carcinoma
Interventions
DRUG
No Results Yet
NCT03672539 | ACTIVE_NOT_RECRUITING | PHASE2
50 Participants

Liposome-encapsulated Daunorubicin-Cytarabine and Gemtuzumab Ozogamicin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) or High Risk Myelodysplastic Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2018-11-07
Completion: 2027-11-30
Conditions
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome Chronic Myelomonocytic Leukemia High Risk Myelodysplastic Syndrome Myelodysplastic Syndrome Recurrent Acute Myeloid Leukemia Refractory Acute Myeloid Leukemia
Interventions
DRUG OTHER
No Results Yet
NCT03657394 | ACTIVE_NOT_RECRUITING | NA
3442 Participants

Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2022-10-17
Completion: 2025-09-01
Conditions
Hypoxic-Ischemic Encephalopathy Birth Asphyxia
Interventions
OTHER
No Results Yet
NCT03653637 | COMPLETED | NA
294 Participants

Group ("Project Life Force") vs. Individual Suicide Safety Planning RCT

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2018-10-15
Completion: 2023-12-31
Conditions
Suicide
Interventions
BEHAVIORAL
NCT03652064 | ACTIVE_NOT_RECRUITING | PHASE3
395 Participants
NCT03650114 | ACTIVE_NOT_RECRUITING | PHASE3
1882 Participants

Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2018-12-28
Completion: 2027-12-30
Conditions
Relapsing Multiple Sclerosis
Interventions
BIOLOGICAL
No Results Yet
NCT03617939 | RECRUITING
20000 Participants

A Lifetime Partnership With Patients Who Have or May be at Risk of Having Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2015-09-16
Completion: 2035-09-30
Conditions
Cancer Risk
Interventions
PROCEDURE OTHER
No Results Yet
NCT03616483 | RECRUITING
2500 Participants

The Indiana Myeloma Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-11-10
Start Date: 2018-06-18
Completion: 2028-06-30
Conditions
Plasma Cell Dyscrasias
Interventions
OTHER
No Results Yet
NCT03583684 | RECRUITING | NA
36 Participants

Neuroimaging Predictors of Improvement to Pivotal Response Treatment (PRT) in Young Children With Autism

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2018-12-07
Completion: 2026-11-30
Conditions
Autism Spectrum Disorder Autism
Interventions
BEHAVIORAL
No Results Yet
NCT03578367 | COMPLETED | PHASE2
104 Participants

Study of Efficacy and Safety of Asciminib in Combination With Imatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase (CML-CP)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2018-11-22
Completion: 2021-11-08
Conditions
CML Chronic Myelogenous Leukemia Leukemia, Myeloid Chronic Hematologic Diseases
Interventions
DRUG
NCT03565783 | ACTIVE_NOT_RECRUITING | PHASE2
44 Participants

Cemiplimab in Treating Patients With Recurrent and Resectable Stage II-IV Head and Neck Cutaneous Squamous Cell Cancer Before Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2018-07-03
Completion: 2025-12-31
Conditions
Recurrent Cutaneous Squamous Cell Carcinoma of the Head and Neck Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck Stage II Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8
Interventions
BIOLOGICAL
No Results Yet
NCT03527537 | RECRUITING | PHASE4
416 Participants

Gestational Diabetes and Pharmacotherapy (GAP)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2021-05-04
Completion: 2026-03-31
Conditions
Gestational Diabetes
Interventions
DRUG
No Results Yet
NCT03527277 | COMPLETED | NA
56 Participants

Orange Juice And Sugar Intervention Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2018-06-01
Completion: 2023-05-28
Conditions
Cardiovascular Risk Factor Type2 Diabetes Mellitus Insulin Sensitivity Metabolic Syndrome
Interventions
OTHER
NCT03520647 | RECRUITING | PHASE2
56 Participants

Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-10
Start Date: 2019-02-19
Completion: 2026-06-01
Conditions
Severe Aplastic Anemia (SAA) Hypo-Plastic Myelodysplastic Syndrome (MDS) Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions
DRUG OTHER
No Results Yet
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