Clinical Trials
1334
Participants
A Frontline Therapy Trial in Participants With Advanced Classical Hodgkin Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2012-11-09
Completion:
2017-04-20
Conditions
Hodgkin Lymphoma
Interventions
DRUG
125
Participants
Erlotinib Hydrochloride and Cabozantinib-s-Malate Alone or in Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2013-02-13
Completion:
2015-08-14
Conditions
Recurrent Lung Non-Small Cell Carcinoma
Stage IV Lung Non-Small Cell Cancer AJCC v7
Interventions
DRUG
OTHER
68
Participants
Cognitive Behavioral Therapy and Multimodal Therapy in Treating Sleep Disturbance in Patients With Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2014-01-15
Completion:
2025-12-31
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm
Sleep Disorder
Interventions
OTHER
DRUG
PROCEDURE
No Results Yet
25
Participants
AAV2-GDNF for Advanced Parkinson s Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2013-03-13
Completion:
2022-02-04
Conditions
Parkinson's Disease
Interventions
GENETIC
No Results Yet
28
Participants
Gene Transfer for X-Linked Severe Combined Immunodeficiency in Newly Diagnosed Infants
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2016-08-17
Completion:
2026-08-31
Conditions
Severe Combined Immunodeficiency Disease, X-linked
Interventions
GENETIC
DRUG
DEVICE
No Results Yet
700
Participants
The Hurria Older PatiEnts (HOPE) With Breast Cancer Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2011-09-09
Completion:
2018-12-02
Conditions
Breast Cancer
No Results Yet
44
Participants
Acute Changes in Endothelial Function in Germ Cell Tumor Patients Treated With Cisplatin and Untreated Germ Cell Tumor Controls
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2011-10-11
Completion:
2026-10-31
Conditions
Germ Cell Cancer
Interventions
OTHER
No Results Yet
120
Participants
Combination of Lenalidomide and Rituximab in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL-SLL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2011-12-12
Completion:
2025-11-30
Conditions
Leukemia
Lymphoma
Interventions
DRUG
No Results Yet
40
Participants
Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2012-09-25
Completion:
2032-12-31
Conditions
X-linked Severe Combined Immunodeficiency (XSCID)
Interventions
BIOLOGICAL
DRUG
No Results Yet
1328
Participants
Evaluation and Diagnosis of Potential Research Subjects With Traumatic Brain Injury
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2013-01-10
Conditions
Traumatic Brain Injury
No Results Yet
135
Participants
Ofatumumab and Bendamustine Hydrochloride With or Without Bortezomib in Treating Patients With Untreated Follicular Non-Hodgkin Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2011-04-28
Completion:
2017-05-24
Conditions
Ann Arbor Stage III Grade 1 Follicular Lymphoma
Ann Arbor Stage III Grade 2 Follicular Lymphoma
Ann Arbor Stage III Grade 3 Follicular Lymphoma
Ann Arbor Stage IV Grade 1 Follicular Lymphoma
Ann Arbor Stage IV Grade 2 Follicular Lymphoma
Ann Arbor Stage IV Grade 3 Follicular Lymphoma
Grade 3a Follicular Lymphoma
Interventions
DRUG
RADIATION
OTHER
BIOLOGICAL
PROCEDURE
1673
Participants
Ipilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2011-05-25
Completion:
2019-02-15
Conditions
Melanoma of Unknown Primary
Recurrent Melanoma
Stage IIIB Cutaneous Melanoma AJCC v7
Stage IIIC Cutaneous Melanoma AJCC v7
Stage IV Cutaneous Melanoma AJCC v6 and v7
Interventions
BIOLOGICAL
OTHER
5018
Participants
Tamoxifen Citrate, Letrozole, Anastrozole, or Exemestane With or Without Chemotherapy in Treating Patients With Invasive RxPONDER Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2011-01-15
Completion:
2023-02-01
Conditions
Breast Ductal Carcinoma In Situ
Invasive Breast Carcinoma
Multicentric Breast Carcinoma
Multifocal Breast Carcinoma
Synchronous Bilateral Breast Carcinoma
Interventions
DRUG
OTHER
50126
Participants
Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2012-04-30
Completion:
2028-12-01
Conditions
Colorectal Cancer
Interventions
PROCEDURE
No Results Yet
59
Participants
Developing Biomarkers of Dietary Intake
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2010-10-24
Completion:
2020-03-31
Conditions
Diet Therapy
Healthy Volunteers
Interventions
OTHER
No Results Yet
493
Participants
Culturally-Informed Counseling in Latinas at High Risk for Hereditary Breast or Ovarian Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2010-09-03
Completion:
2016-11-10
Conditions
No Evidence of Disease
BRCA1 Syndrome
BRCA2 Syndrome
Hereditary Female Breast Carcinoma
Hereditary Ovarian Carcinoma
Interventions
OTHER
No Results Yet
120
Participants
Dynamic Contrast Enhancement Computed Tomography for Evaluating Tumor Perfusion in Patients With Metastatic Renal Cell Carcinoma Receiving Targeted Therapies: Renal Cell Carcinoma (RCC) Scramble
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2011-01-05
Completion:
2029-04-30
Conditions
Renal Cell Carcinoma
Interventions
PROCEDURE
No Results Yet
9
Participants
Vaccine Therapy in Treating Patients With Lymphoplasmacytic Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2015-02-26
Completion:
2026-02-20
Conditions
Lymphoplasmacytic Lymphoma
Interventions
BIOLOGICAL
OTHER
No Results Yet
203
Participants
Cellular and Molecular Characterization of the Immune Response in Healthy NIH Employees atBaseline, and After Immunization With the H1N1 or Seasonal Influenza Vaccines
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2009-09-18
Conditions
Healthy Volunteers
Influenza
No Results Yet
155
Participants
Neurobehavioral Functioning in Pediatric Brain Tumor Patients After Proton Beam Radiation Treatment
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2009-10-31
Completion:
2017-12-31
Conditions
Brain Tumor
Central Nervous System Neoplasms
No Results Yet
120
Participants
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2010-12-10
Completion:
2027-12-30
Conditions
Severe Aplastic Anemia
MDS (Myelodysplastic Syndrome)
Interventions
DEVICE
OTHER
No Results Yet
226
Participants
Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2011-01-24
Completion:
2019-01-25
Conditions
Light Chain Deposition Disease
Smoldering Multiple Myeloma
Interventions
OTHER
DRUG
15000
Participants
Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2010-08-30
Conditions
Malaria
No Results Yet
128
Participants
Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2010-07-09
Completion:
2025-12-31
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
RADIATION
OTHER
No Results Yet
104
Participants
Excision Followed by Radiofrequency Ablation for Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2010-06-30
Completion:
2027-06-30
Conditions
Breast Cancer
Interventions
DEVICE
No Results Yet
51
Participants
Smoking Cessation Treatment for Head & Neck Cancer Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2010-03-24
Completion:
2027-09-30
Conditions
Head and Neck Cancer
Smoking Cessation
Interventions
BEHAVIORAL
DRUG
No Results Yet
5326
Participants
Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and Testing
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2010-03-02
Conditions
Exposure
No Results Yet
300
Participants
Top-Down Attentional Control of Visual-Processing
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2012-07-23
Conditions
Focal Brain Lesion
Focal Lesions
fMRI
No Results Yet
4902
Participants
Health Behavior in School-Age Children: NEXT Longitudinal Study 2009-2016
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2010-02-17
Conditions
Adolescent Health
No Results Yet
2415
Participants
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2009-10-07
Conditions
Endocrine Tumors
Thyroid Neoplasms
Parathyroid Neoplasms
Adrenal Neoplasm
Neuroblastoma
No Results Yet
35
Participants
Aggressive Local Therapy for Limited Bone-Only Metastasis to Improve Progression-Free Survival in Breast Cancer Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2009-06-24
Completion:
2025-12-01
Conditions
Breast Cancer
Interventions
DRUG
PROCEDURE
No Results Yet
116
Participants
Ixabepilone in Treating Participants With Significant Residual Disease of HER2/Neu Negative Invasive Breast Cancer After Systemic Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2009-03-30
Completion:
2026-12-31
Conditions
Bilateral Breast Carcinoma
HER2/Neu Negative
Invasive Breast Carcinoma
Interventions
OTHER
DRUG
No Results Yet
224
Participants
Mycobacterial and Opportunistic Infections in HIV-Negative Thai and Taiwanese Patients Associated With Autoantibodies to Interferon-gamma
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2010-01-07
Conditions
Nontuberculous Mycobacteria
Mycobacterium Tuberculosis
Opportunistic Infections
No Results Yet
35
Participants
Natural Killer Cells and Bortezomib to Treat Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2008-08-01
Completion:
2021-04-06
Conditions
Chronic Myeloid Leukemia (CML)
Pancreatic Ca
Colon/Rectal Ca
Multiple Myeloma
Carcinoma, Non-Small -Cell Lung
Interventions
DRUG
BIOLOGICAL
No Results Yet
80
Participants
A New Method for Determining Gastric Acid Output Using a Wireless Capsule
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2008-06-18
Conditions
Gastric Acid Secretory Disorders
Interventions
DEVICE
DRUG
No Results Yet
90
Participants
Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune Mechanisms
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2008-03-31
Completion:
2026-07-31
Conditions
Sleep Disorders
Sleep Initiation and Maintenance Disorders
Dyssomnias
Mental Disorders
Nervous System Diseases
Interventions
BEHAVIORAL
No Results Yet
66
Participants
Growth Hormone Administration and the Human Immune System
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2006-10-19
Completion:
2014-10-06
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
4970
Participants
A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2007-05-31
Conditions
Crohn's Disease
Ulcerative Colitis
Indeterminate Colitis
Inflammatory Bowel Diseases
Interventions
BIOLOGICAL
DRUG
No Results Yet
403
Participants
Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2008-08-08
Completion:
2018-06-05
Conditions
Neck Squamous Cell Carcinoma of Unknown Primary
Recurrent Hypopharyngeal Squamous Cell Carcinoma
Recurrent Laryngeal Squamous Cell Carcinoma
Recurrent Laryngeal Verrucous Carcinoma
Recurrent Lip and Oral Cavity Squamous Cell Carcinoma
Recurrent Neck Squamous Cell Carcinoma of Unknown Primary
Recurrent Oral Cavity Verrucous Carcinoma
Recurrent Oropharyngeal Squamous Cell Carcinoma
Recurrent Salivary Gland Carcinoma
Recurrent Sinonasal Squamous Cell Carcinoma
Salivary Gland Squamous Cell Carcinoma
Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7
Stage IV Major Salivary Gland Cancer AJCC v7
Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IVA Laryngeal Verrucous Carcinoma AJCC v7
Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVA Major Salivary Gland Cancer AJCC v7
Stage IVA Oral Cavity Cancer AJCC v6 and v7
Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVA Sinonasal Squamous Cell Carcinoma AJCC v7
Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IVB Laryngeal Verrucous Carcinoma AJCC v7
Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVB Major Salivary Gland Cancer AJCC v7
Stage IVB Oral Cavity Cancer AJCC v6 and v7
Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVB Sinonasal Squamous Cell Carcinoma AJCC v7
Stage IVC Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IVC Laryngeal Verrucous Carcinoma AJCC v7
Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVC Major Salivary Gland Cancer AJCC v7
Stage IVC Oral Cavity Cancer AJCC v6 and v7
Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVC Sinonasal Squamous Cell Carcinoma AJCC v7
Tongue Carcinoma
Interventions
BIOLOGICAL
DRUG
OTHER
15842
Participants
Psoriasis Longitudinal Assessment and Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2007-06-21
Completion:
2029-12-31
Conditions
Psoriasis
No Results Yet
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