Clinical Trials
50126
Participants
Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2012-04-30
Completion:
2028-12-01
Conditions
Colorectal Cancer
Interventions
PROCEDURE
No Results Yet
59
Participants
Developing Biomarkers of Dietary Intake
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2010-10-24
Completion:
2020-03-31
Conditions
Diet Therapy
Healthy Volunteers
Interventions
OTHER
No Results Yet
493
Participants
Culturally-Informed Counseling in Latinas at High Risk for Hereditary Breast or Ovarian Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2010-09-03
Completion:
2016-11-10
Conditions
No Evidence of Disease
BRCA1 Syndrome
BRCA2 Syndrome
Hereditary Female Breast Carcinoma
Hereditary Ovarian Carcinoma
Interventions
OTHER
No Results Yet
120
Participants
Dynamic Contrast Enhancement Computed Tomography for Evaluating Tumor Perfusion in Patients With Metastatic Renal Cell Carcinoma Receiving Targeted Therapies: Renal Cell Carcinoma (RCC) Scramble
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2011-01-05
Completion:
2029-04-30
Conditions
Renal Cell Carcinoma
Interventions
PROCEDURE
No Results Yet
9
Participants
Vaccine Therapy in Treating Patients With Lymphoplasmacytic Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2015-02-26
Completion:
2026-02-20
Conditions
Lymphoplasmacytic Lymphoma
Interventions
BIOLOGICAL
OTHER
No Results Yet
203
Participants
Cellular and Molecular Characterization of the Immune Response in Healthy NIH Employees atBaseline, and After Immunization With the H1N1 or Seasonal Influenza Vaccines
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2009-09-18
Conditions
Healthy Volunteers
Influenza
No Results Yet
155
Participants
Neurobehavioral Functioning in Pediatric Brain Tumor Patients After Proton Beam Radiation Treatment
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2009-10-31
Completion:
2017-12-31
Conditions
Brain Tumor
Central Nervous System Neoplasms
No Results Yet
120
Participants
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2010-12-10
Completion:
2027-12-30
Conditions
Severe Aplastic Anemia
MDS (Myelodysplastic Syndrome)
Interventions
DEVICE
OTHER
No Results Yet
226
Participants
Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2011-01-24
Completion:
2019-01-25
Conditions
Light Chain Deposition Disease
Smoldering Multiple Myeloma
Interventions
OTHER
DRUG
15000
Participants
Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2010-08-30
Conditions
Malaria
No Results Yet
128
Participants
Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2010-07-09
Completion:
2025-12-31
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
RADIATION
OTHER
No Results Yet
104
Participants
Excision Followed by Radiofrequency Ablation for Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2010-06-30
Completion:
2027-06-30
Conditions
Breast Cancer
Interventions
DEVICE
No Results Yet
51
Participants
Smoking Cessation Treatment for Head & Neck Cancer Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2010-03-24
Completion:
2027-09-30
Conditions
Head and Neck Cancer
Smoking Cessation
Interventions
BEHAVIORAL
DRUG
No Results Yet
5326
Participants
Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and Testing
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2010-03-02
Conditions
Exposure
No Results Yet
300
Participants
Top-Down Attentional Control of Visual-Processing
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2012-07-23
Conditions
Focal Brain Lesion
Focal Lesions
fMRI
No Results Yet
4902
Participants
Health Behavior in School-Age Children: NEXT Longitudinal Study 2009-2016
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2010-02-17
Conditions
Adolescent Health
No Results Yet
2415
Participants
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2009-10-07
Conditions
Endocrine Tumors
Thyroid Neoplasms
Parathyroid Neoplasms
Adrenal Neoplasm
Neuroblastoma
No Results Yet
35
Participants
Aggressive Local Therapy for Limited Bone-Only Metastasis to Improve Progression-Free Survival in Breast Cancer Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2009-06-24
Completion:
2025-12-01
Conditions
Breast Cancer
Interventions
DRUG
PROCEDURE
No Results Yet
116
Participants
Ixabepilone in Treating Participants With Significant Residual Disease of HER2/Neu Negative Invasive Breast Cancer After Systemic Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2009-03-30
Completion:
2026-12-31
Conditions
Bilateral Breast Carcinoma
HER2/Neu Negative
Invasive Breast Carcinoma
Interventions
OTHER
DRUG
No Results Yet
224
Participants
Mycobacterial and Opportunistic Infections in HIV-Negative Thai and Taiwanese Patients Associated With Autoantibodies to Interferon-gamma
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2010-01-07
Conditions
Nontuberculous Mycobacteria
Mycobacterium Tuberculosis
Opportunistic Infections
No Results Yet
35
Participants
Natural Killer Cells and Bortezomib to Treat Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2008-08-01
Completion:
2021-04-06
Conditions
Chronic Myeloid Leukemia (CML)
Pancreatic Ca
Colon/Rectal Ca
Multiple Myeloma
Carcinoma, Non-Small -Cell Lung
Interventions
DRUG
BIOLOGICAL
No Results Yet
80
Participants
A New Method for Determining Gastric Acid Output Using a Wireless Capsule
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2008-06-18
Conditions
Gastric Acid Secretory Disorders
Interventions
DEVICE
DRUG
No Results Yet
90
Participants
Tai Chi Effects on Chronic Insomnia in Breast Cancer Survivors: Immune Mechanisms
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2008-03-31
Completion:
2026-07-31
Conditions
Sleep Disorders
Sleep Initiation and Maintenance Disorders
Dyssomnias
Mental Disorders
Nervous System Diseases
Interventions
BEHAVIORAL
No Results Yet
66
Participants
Growth Hormone Administration and the Human Immune System
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2006-10-19
Completion:
2014-10-06
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
4970
Participants
A Multicenter, Prospective, Long-term, Observational Registry of Pediatric Patients With Inflammatory Bowel Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2007-05-31
Conditions
Crohn's Disease
Ulcerative Colitis
Indeterminate Colitis
Inflammatory Bowel Diseases
Interventions
BIOLOGICAL
DRUG
No Results Yet
403
Participants
Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2008-08-08
Completion:
2018-06-05
Conditions
Neck Squamous Cell Carcinoma of Unknown Primary
Recurrent Hypopharyngeal Squamous Cell Carcinoma
Recurrent Laryngeal Squamous Cell Carcinoma
Recurrent Laryngeal Verrucous Carcinoma
Recurrent Lip and Oral Cavity Squamous Cell Carcinoma
Recurrent Neck Squamous Cell Carcinoma of Unknown Primary
Recurrent Oral Cavity Verrucous Carcinoma
Recurrent Oropharyngeal Squamous Cell Carcinoma
Recurrent Salivary Gland Carcinoma
Recurrent Sinonasal Squamous Cell Carcinoma
Salivary Gland Squamous Cell Carcinoma
Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7
Stage IV Major Salivary Gland Cancer AJCC v7
Stage IVA Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IVA Laryngeal Verrucous Carcinoma AJCC v7
Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVA Major Salivary Gland Cancer AJCC v7
Stage IVA Oral Cavity Cancer AJCC v6 and v7
Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVA Sinonasal Squamous Cell Carcinoma AJCC v7
Stage IVB Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IVB Laryngeal Verrucous Carcinoma AJCC v7
Stage IVB Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVB Major Salivary Gland Cancer AJCC v7
Stage IVB Oral Cavity Cancer AJCC v6 and v7
Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVB Sinonasal Squamous Cell Carcinoma AJCC v7
Stage IVC Laryngeal Squamous Cell Carcinoma AJCC v7
Stage IVC Laryngeal Verrucous Carcinoma AJCC v7
Stage IVC Lip and Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7
Stage IVC Major Salivary Gland Cancer AJCC v7
Stage IVC Oral Cavity Cancer AJCC v6 and v7
Stage IVC Oropharyngeal Squamous Cell Carcinoma AJCC v7
Stage IVC Sinonasal Squamous Cell Carcinoma AJCC v7
Tongue Carcinoma
Interventions
BIOLOGICAL
DRUG
OTHER
15842
Participants
Psoriasis Longitudinal Assessment and Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2007-06-21
Completion:
2029-12-31
Conditions
Psoriasis
No Results Yet
48
Participants
Sorafenib in Combination With Carboplatin and Paclitaxel in Treating Participants With Metastatic or Recurrent Head and Neck Squamous Cell Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2007-04-25
Completion:
2025-12-31
Conditions
Metastatic Head and Neck Squamous Cell Carcinoma
Metastatic Squamous Cell Carcinoma of the Hypopharynx
Metastatic Squamous Cell Carcinoma of the Larynx
Metastatic Squamous Cell Carcinoma of the Oral Cavity
Metastatic Squamous Cell Carcinoma of the Oropharynx
Recurrent Head and Neck Squamous Cell Carcinoma
Recurrent Hypopharyngeal Squamous Cell Carcinoma
Recurrent Laryngeal Squamous Cell Carcinoma
Recurrent Oral Cavity Squamous Cell Carcinoma
Recurrent Oropharyngeal Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
2000
Participants
Detection and Characterization of Infections and Infection Susceptibility
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2007-01-02
Conditions
Immune Deficiencies
No Results Yet
64
Participants
Sunitinib Malate With Hormonal Ablation for Patients Who Will Have Prostatectomy
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2006-05-15
Completion:
2025-12-31
Conditions
Prostate Cancer
Interventions
DRUG
PROCEDURE
No Results Yet
57
Participants
Real-Time Image Guided Lymphatic Mapping and Nodal Targeting in Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-10
Start Date:
2009-02-18
Completion:
2017-09-01
Conditions
Lung Cancer
Interventions
DRUG
No Results Yet
1750
Participants
Collection of Blood From Patients With Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
2002-07-16
Conditions
Prostate Cancer
Breast Cancer
Colon Cancer
Lung Cancer
Liver Cancer
No Results Yet
5950
Participants
Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
1998-03-12
Conditions
Malignant Neoplasms
Hereditary Neoplastic Syndromes
Kidney Cancer
Renal Cancer
Bladder Cancer
No Results Yet
Multicenter Study of Silent Myocardial Ischemia (MSSMI)
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
1988-04-30
Conditions
Cardiovascular Diseases
Coronary Disease
Myocardial Ischemia
Heart Diseases
Myocardial Infarction
Angina, Unstable
Arrhythmia
No Results Yet
700
Participants
A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients With Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
1996-06-13
Conditions
Lyme Disease
No Results Yet
3600
Participants
Detection and Characterization of Host Defense Defects
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
1993-09-01
Conditions
Immune Defects
No Results Yet
400
Participants
Viral Load in Blood and Lymph Tissues in People Living With HIV
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
1992-08-26
Conditions
HIV
No Results Yet
2419
Participants
Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIV
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
1993-03-09
Conditions
HIV
Immunodeficiencies
Infectious Diseases
No Results Yet
5000
Participants
Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-10
Start Date:
1990-12-05
Conditions
Kidney Cancer
Urologic Malignant Disorders
Renal Cell Carcinoma
Familial Renal Cancer (FRC)
Clear Cell Renal Cancer
No Results Yet
60
Participants
A Study of Combogesic® IV (Intravenous) in Pediatric Patients With Acute Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-06
Start Date:
2026-02-28
Completion:
2026-10-31
Conditions
Acute Pain
Interventions
DRUG
No Results Yet
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