Clinical Trials

NCT07215520 | RECRUITING | PHASE2

200 Participants

Safety and Tolerability of a Newcastle Disease Virus-Based Mucosal COVID-19 Vaccine in Previously Vaccinated Adults

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-03

Completion: 2026-08-19

Conditions

COVID-19

Interventions

BIOLOGICAL

No Results Yet

NCT07215455 | COMPLETED | NA

50 Participants

Ashwagandha Extract for Weight and Stress Management in Overweight and Obese Adults

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-06-17

Completion: 2025-10-22

Conditions

Weight Management Stress

Interventions

DIETARY_SUPPLEMENT OTHER

No Results Yet

NCT07215234 | RECRUITING | PHASE1/PHASE2

104 Participants

A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-10-09

Completion: 2027-10-13

Conditions

Geographic Atrophy

Interventions

DRUG

No Results Yet

NCT07211035 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated: 2025-11-06

No Results Yet

NCT07210580 | NOT_YET_RECRUITING | NA

250 Participants

Testing the Impact of Measurement-Based Care on Quality of Life and Disease Management Among Veterans With Inflammatory Bowel Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2026-01-05

Completion: 2028-12-29

Conditions

Inflammatory Bowel Disease

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT07203378 | RECRUITING | PHASE2

80 Participants

Nurturing Exercise Routine for Greater Improvement in Zest and Energy on Enhertu

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-04

Completion: 2027-11-30

Conditions

Metastatic Breast Cancer

Interventions

OTHER

No Results Yet

NCT07199309 | RECRUITING | PHASE2

30 Participants

A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-09-26

Completion: 2026-07-31

Conditions

Hypertriglyceridemia

Interventions

DRUG

No Results Yet

NCT07191314 | RECRUITING | NA

20 Participants

Long-term Evaluation of a Nasopharyngeal Airway

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-10-21

Completion: 2027-09-30

Conditions

Sleep Apnea, Obstructive

Interventions

DEVICE

No Results Yet

NCT07187401 | RECRUITING | PHASE1/PHASE2

24 Participants

A First-in-Human Safety and Efficacy Study of ALN-CFB, a Small Interfering RNA (siRNA) Targeting Complement Factor B, in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria With Persistent Anemia on a C5 Inhibitor

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-28

Completion: 2029-10-11

Conditions

Paroxysmal Nocturnal Hemoglobinuria (PNH) Persistent Anemia

Interventions

DRUG

No Results Yet

NCT07182149 | RECRUITING | PHASE1

150 Participants

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-10-30

Completion: 2027-05-30

Conditions

HNSCC ESCC Esophageal Adenocarcinoma Gastric Adenocarcinoma GEJ Adenocarcinoma Ovarian Cancer NSCLC Cervical Cancer Endometrial Cancer Triple Negative Breast Cancer (TNBC)

Interventions

DRUG

No Results Yet

NCT07175285 | RECRUITING

223 Participants

A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants

Study Type: OBSERVATIONAL

Last Updated: 2025-11-06

Start Date: 2025-10-08

Completion: 2028-03-01

Conditions

Systemic Lupus Erythematosus (SLE)

Interventions

DRUG

No Results Yet

NCT07173088 | RECRUITING | NA

60 Participants

Efficacy and Clinical Feasibility of the Ankle Muscle Power (AMP) Program for Return to Duty After an Ankle Fracture

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-30

Completion: 2028-03-31

Conditions

Ankle Fractures

Interventions

OTHER BEHAVIORAL

No Results Yet

NCT07168499 | RECRUITING | NA

160 Participants

Diet and Stress Management Combined With Advanced Therapy for Crohn's and Ulcerative Colitis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-09-15

Completion: 2027-05-01

Conditions

IBD (Inflammatory Bowel Disease)

Interventions

BEHAVIORAL

No Results Yet

NCT07161765 | NOT_YET_RECRUITING | NA

100 Participants

Rectal Evacuation Disorders and Straining-associated Symptoms in Bleeding Hemorrhoids

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-30

Completion: 2026-09-30

Conditions

Bleeding Hemorrhoids Rectal Evacuation Disorders

Interventions

DEVICE

No Results Yet

NCT07160179 | RECRUITING | PHASE1/PHASE2

66 Participants

Study to Assess the Adverse Events and How Intravitreal ABBV-6628 Moves Through the Body of Adult Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-08-13

Completion: 2029-10-31

Conditions

Geographic Atrophy Age-Related Macular Degeneration

Interventions

DRUG

No Results Yet

NCT07155902 | NOT_YET_RECRUITING | NA

5000 Participants

Implementing WHO HEARTS-D Guidelines in Bangladesh for Diabetes Control and Prevention

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2026-01-31

Completion: 2029-09-30

Conditions

Type 2 Diabetes (T2DM)

Interventions

OTHER

No Results Yet

NCT07153900 | ACTIVE_NOT_RECRUITING | NA

24 Participants

BACK4 Safety Evaluation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-10-01

Completion: 2025-10-31

Conditions

Safety and Tolerability in Healthy Subjects

Interventions

DEVICE

No Results Yet

NCT07145346 | NOT_YET_RECRUITING | PHASE4

80 Participants

Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-13

Completion: 2027-08-31

Conditions

Rib Fractures

Interventions

DRUG

No Results Yet

NCT07143370 | COMPLETED | NA

30 Participants

Microbial Colonization in Three Dimensional (3D) Printed Orthodontic Clear Aligners

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-09-02

Completion: 2025-10-17

Conditions

Orthodontic Aligner Microbial Colonization

Interventions

DEVICE

No Results Yet

NCT07142499 | RECRUITING | NA

7 Participants

Memory Support System for Older Chinese Americans With Mild Cognitive Impairment

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-07-29

Completion: 2026-03-31

Conditions

Mild Cognitive Impairment (MCI)

Interventions

BEHAVIORAL

No Results Yet

NCT07132177 | RECRUITING | PHASE2

20 Participants

Targeted Naltrexone to Support Individuals Participating in Dry January

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-03

Completion: 2026-04-01

Conditions

Alcohol Misuse

Interventions

DRUG

No Results Yet

NCT07121972 | RECRUITING | NA

400 Participants

Mirai-MRI: Validation of AI Models for Breast Cancer Risk

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-03

Completion: 2027-01-31

Conditions

Cancer Risk Breast Cancer Risk

Interventions

PROCEDURE DEVICE

No Results Yet

NCT07118202 | RECRUITING | NA

198 Participants

TheraBionic P1 Device in Subjects With Advanced Hepatocellular Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-10-20

Completion: 2027-08-31

Conditions

Hepatocellular Carcinoma Recurrent

Interventions

DEVICE

No Results Yet

NCT07115329 | NOT_YET_RECRUITING | PHASE2

164 Participants

GATE-251 or Placebo for the Reduction of Symptoms of Major Depressive Disorder With Comorbid Anxiety and Insomnia

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-30

Completion: 2027-11-30

Conditions

Major Depressive Disorder

Interventions

DRUG

No Results Yet

NCT07113691 | NOT_YET_RECRUITING | PHASE1

15 Participants

Iadademstat + SBRT With Atezo in ES-SCLC

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-30

Completion: 2029-11-30

Conditions

Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Interventions

DRUG RADIATION

No Results Yet

NCT07109414 | RECRUITING | PHASE2/PHASE3

380 Participants

Trial of NP-G2-044 (Prilukae) Combined With PLD for Treatment of Platinum-Resistant Ovarian Cancer (ULTIMUS-1)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-30

Completion: 2028-10-25

Conditions

Platinum-resistant Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT07109349 | RECRUITING | NA

50 Participants

tAN for First Responders

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-09-10

Completion: 2026-02-10

Conditions

Mental Fatigue Mental Stress

Interventions

DEVICE

No Results Yet

NCT07106762 | RECRUITING | PHASE2/PHASE3

470 Participants

Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-09-30

Completion: 2029-01-26

Conditions

Urothelial Cancer

Interventions

DRUG

No Results Yet

NCT07098299 | RECRUITING | PHASE1

60 Participants

Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-09-18

Completion: 2027-07-07

Conditions

Advanced Solid Tumor

Interventions

DRUG

No Results Yet

NCT07094113 | RECRUITING | PHASE1

434 Participants

AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-07-31

Completion: 2027-09-06

Conditions

KRAS Altered Advanced or Metastatic Solid Tumors

Interventions

DRUG

No Results Yet

NCT07085039 | RECRUITING | PHASE2

14 Participants

Ruxolitinib in Previously Treated Idiopathic Multicentric Castleman Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-12-15

Completion: 2028-12-31

Conditions

Castleman's Disease (CD) Idiopathic Multicentric Castleman's Disease

Interventions

DRUG

No Results Yet

NCT07071207 | RECRUITING | NA

132 Participants

Effect of Text Message Reminders on M-ISI Score After Prostate Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-09-15

Completion: 2028-05-01

Conditions

Incontinence, Urinary Stress Prostate Cancer Benign Prostate Hyperplasia

Interventions

BEHAVIORAL

No Results Yet

NCT07069738 | RECRUITING | NA

850 Participants

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-10-22

Completion: 2029-11-30

Conditions

Heart Failure - NYHA II - IV

Interventions

DEVICE

No Results Yet

NCT07059091 | NOT_YET_RECRUITING | PHASE2

334 Participants

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2026-01-31

Completion: 2031-01-31

Conditions

Chronic Obstructive Pulmonary Disease (COPD) Allergies

Interventions

DRUG

No Results Yet

NCT07055594 | RECRUITING | PHASE1/PHASE2

76 Participants

A Study to Investigate Safety and Preliminary Efficacy of SOA101 in Adult Subjects With Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-07-30

Completion: 2028-02-29

Conditions

Solid Tumors

Interventions

DRUG

No Results Yet

NCT07036705 | RECRUITING | NA

40 Participants

Optimizing an Integrated Mind and Body Treatment for Insomnia: The SLEEPS Study 2

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-09-29

Completion: 2027-07-31

Conditions

Insomnia Disorder

Interventions

BEHAVIORAL DEVICE

No Results Yet

NCT07032636 | NOT_YET_RECRUITING | NA

450 Participants

Reducing Crises and Suicide Within the Idaho Army National Guard

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2026-01-01

Completion: 2028-05-01

Conditions

Crisis Response Plan Crisis Intervention

Interventions

BEHAVIORAL

No Results Yet

NCT07029776 | NOT_YET_RECRUITING | PHASE2

50 Participants

MMulti-Immune HR; Multi-Target Immunotherapy for High-Risk Multiple Myeloma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2026-04-01

Completion: 2030-04-01

Conditions

Multiple Myeloma (MM)

Interventions

DRUG PROCEDURE

No Results Yet

NCT07020520 | RECRUITING | NA

60 Participants

EvaluatioN of Optilume Drug-Coated Balloon for the Endoscopic Treatment of UREteric Strictures

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-10-01

Completion: 2027-02-28

Conditions

Ureteral Stricture

Interventions

DEVICE

No Results Yet

NCT07018869 | RECRUITING | PHASE3

1057 Participants

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-10-15

Completion: 2029-05-23

Conditions

Colorectal Cancer Stage II Colorectal Cancer Stage III

Interventions

OTHER

No Results Yet