Clinical Trials

NCT06502691 | RECRUITING | PHASE1/PHASE2

22 Participants

[18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-22

Completion: 2027-12-31

Conditions

Anatomic Stage IV Breast Cancer AJCC v8 Metastatic Breast Carcinoma

Interventions

OTHER PROCEDURE RADIATION DRUG

No Results Yet

NCT06501963 | COMPLETED | PHASE4

51 Participants

Revealing Protective Immunity to Influenza Using Systems Immunology

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-10-14

Completion: 2025-04-01

Conditions

Influenza

Interventions

BIOLOGICAL

No Results Yet

NCT06487533 | RECRUITING

20 Participants

Sensing Physiological Symptoms of Opioid Withdrawal and Cravings in Patients With Opioid Use Disorder

Study Type: OBSERVATIONAL

Last Updated: 2025-11-06

Start Date: 2025-02-19

Completion: 2026-03-31

Conditions

Opioid Withdrawal Opioid Use Disorder

Interventions

DEVICE

No Results Yet

NCT06478212 | RECRUITING | PHASE1/PHASE2

42 Participants

Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-01-22

Completion: 2027-11-30

Conditions

IDH1-mutant Glioma IDH2-mutant Glioma

Interventions

DRUG

No Results Yet

NCT06475768 | COMPLETED

48 Participants

The Influence of Menopausal Status on Myocardial Stiffness and Exercise Capacity Among Female Masters Endurance Athletes.

Study Type: OBSERVATIONAL

Last Updated: 2025-11-06

Start Date: 2024-09-14

Completion: 2025-10-06

Conditions

Myocardial Stiffness

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06464315 | NOT_YET_RECRUITING | NA

36 Participants

Functional Substrate-Only Guided VT Ablation

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-11-17

Completion: 2029-09-28

Conditions

Ventricular Tachycardia Sudden Cardiac Death

Interventions

PROCEDURE

No Results Yet

NCT06450639 | RECRUITING | PHASE2

50 Participants

A Study to Assess the Efficacy and Safety of Satralizumab in Duchenne Muscular Dystrophy (DMD)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-04-04

Completion: 2026-11-30

Conditions

Duchenne Muscular Dystrophy

Interventions

DRUG

No Results Yet

NCT06446115 | RECRUITING | NA

70 Participants

Decreasing Chemotherapy Induced Distress Using Immersive Virtual Reality in Patients With Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-11-05

Completion: 2026-01-30

Conditions

Malignant Neoplasm Cancer

Interventions

DEVICE OTHER

No Results Yet

NCT06439277 | RECRUITING | PHASE3

300 Participants

A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-06-03

Completion: 2027-10-31

Conditions

Obesity Weight Gain

Interventions

DRUG

No Results Yet

NCT06435845 | ACTIVE_NOT_RECRUITING | PHASE2

8 Participants

Phase 2 Study on the Pharmacokinetics and Safety of RLYB212 in Pregnant Women at Higher Risk for HPA-1a Alloimmunization

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-11-21

Completion: 2025-10-01

Conditions

Fetal and Neonatal Alloimmune Thrombocytopenia

Interventions

DRUG

No Results Yet

NCT06431256 | TERMINATED | PHASE3

26 Participants

Efficacy, Safety & Pharmacokinetic (PK) Study of HLD200 in Children Aged 4-5 Years With ADHD

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-09-13

Completion: 2025-07-11

Conditions

Attention Deficit Hyperactivity Disorder

Interventions

DRUG

No Results Yet

NCT06418971 | RECRUITING | NA

80 Participants

Testing & Refinement of CarePair: An Assessment and Referral Platform to Support Family Caregivers of Alzheimer's Disease and Related Dementias.

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-09-15

Completion: 2026-05-31

Conditions

Caregiver Burden Caregiver Burnout Dementia

Interventions

BEHAVIORAL

No Results Yet

NCT06413706 | RECRUITING | PHASE2

45 Participants

A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-10-25

Completion: 2027-11-30

Conditions

Glioma

Interventions

DRUG

No Results Yet

NCT06412029 | ENROLLING_BY_INVITATION

144 Participants

Understanding and Enhancing Health-Related Social Needs (HRSN) Screening Among Community Oncology Practices

Study Type: OBSERVATIONAL

Last Updated: 2025-11-06

Start Date: 2024-10-31

Completion: 2026-08-31

Conditions

Cancer

Interventions

OTHER

No Results Yet

NCT06408259 | RECRUITING | PHASE3

194 Participants

Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-04-08

Completion: 2031-04-11

Conditions

Multiple Sclerosis, Relapsing-Remitting

Interventions

DRUG OTHER

No Results Yet

NCT06406790 | RECRUITING | PHASE4

224 Participants

CraniSeal Post Approval Study

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-05-29

Completion: 2026-02-28

Conditions

Leak, Cerebrospinal Fluid

Interventions

DEVICE

No Results Yet

NCT06401044 | RECRUITING | PHASE1/PHASE2

88 Participants

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-05-30

Completion: 2027-02-22

Conditions

Thyroid Eye Disease

Interventions

DRUG OTHER

No Results Yet

NCT06400472 | RECRUITING | PHASE1

495 Participants

A Study of LY4170156 in Participants With Selected Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-05-20

Completion: 2027-02-28

Conditions

Ovarian Neoplasms Endometrial Neoplasms Uterine Cervical Neoplasms Carcinoma, Non-Small-Cell Lung Triple Negative Breast Neoplasms Pancreatic Neoplasm Colorectal Neoplasms

Interventions

DRUG

No Results Yet

NCT06390085 | COMPLETED | NA

5 Participants

Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-04-20

Completion: 2024-04-22

Conditions

Tissue Pain

Interventions

OTHER

Results Available

NCT06374238 | RECRUITING | NA

470 Participants

Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-03-10

Completion: 2027-07-31

Conditions

Pain Sickle Cell Disease

Interventions

BEHAVIORAL

No Results Yet

NCT06372249 | NOT_YET_RECRUITING | PHASE2

105 Participants

A Clinical Trial of Soluble Fiber for Asthma

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-12-31

Completion: 2027-04-30

Conditions

Asthma in Children

Interventions

DRUG

No Results Yet

NCT06372145 | RECRUITING | PHASE3

2500 Participants

A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-04-16

Completion: 2029-04-30

Conditions

Relapsing Multiple Sclerosis Secondary Progressive Multiple Sclerosis Progressive Relapsing Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT06360900 | RECRUITING | NA

80 Participants

Synergistic Gut-brain Axis Modulation Via Vagal Stimulation and Support Therapy in Functional Dyspepsia

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-10-29

Completion: 2029-03-31

Conditions

Functional Dyspepsia

Interventions

DEVICE BEHAVIORAL

No Results Yet

NCT06357754 | RECRUITING

50 Participants

Transgene Assay Testing Service of Tumor Samples From Patients Who Received a Bristol-Myers Squibb Manufactured Gene Modified Cell Therapy and Have a Qualifying Second Primary Malignancy

Study Type: OBSERVATIONAL

Last Updated: 2025-11-06

Start Date: 2023-10-06

Completion: 2038-10-06

Conditions

Non-Hodgkin Lymphoma Chronic Lymphocytic Leukaemia Multiple Myeloma

Interventions

BIOLOGICAL

No Results Yet

NCT06345872 | RECRUITING | NA

165 Participants

Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-12-11

Completion: 2028-01-31

Conditions

Chronic Pain Chronic Insomnia Opioid Use

Interventions

BEHAVIORAL OTHER

No Results Yet

NCT06345183 | COMPLETED

327 Participants

Real-World Outcomes of Nivolumab+Ipilimumab and Pembrolizumab+Lenvatinib Among US Advanced Renal Cell Carcinoma (aRCC) Patients

Study Type: OBSERVATIONAL

Last Updated: 2025-11-06

Start Date: 2024-02-19

Completion: 2024-04-04

Conditions

Advanced Renal Cell Carcinoma (aRCC)

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT06341608 | NOT_YET_RECRUITING | NA

60 Participants

Improving Access to Opioid Use Disorder Treatment Among Marginalized Patients With a Tailored Telehealth Intervention

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-12-01

Completion: 2028-04-30

Conditions

Opioid Use Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06335329 | RECRUITING | NA

200 Participants

Point-of-Care Ultrasound (POCUS) Findings and Impact on Vaping

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-07-17

Completion: 2026-01-31

Conditions

Vaping

Interventions

BEHAVIORAL

No Results Yet

NCT06319963 | RECRUITING | PHASE1/PHASE2

72 Participants

A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-08-08

Completion: 2026-06-30

Conditions

HPV-Related Cervical Carcinoma HPV Positive Oropharyngeal Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT06318169 | RECRUITING | PHASE3

1350 Participants

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-03-13

Completion: 2029-02-28

Conditions

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

Interventions

BIOLOGICAL OTHER

No Results Yet

NCT06316102 | COMPLETED | NA

121 Participants

Promoting Viral Suppression Among Transgender Women Living With HIV in Santo Domingo

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2023-07-14

Completion: 2025-07-30

Conditions

HIV

Interventions

BEHAVIORAL

No Results Yet

NCT06315283 | COMPLETED | PHASE1

153 Participants

An Open-Label Trial to Assess the Comparative Bioavailability of TV-44749 to Oral Olanzapine in Participants With Schizophrenia

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-03-20

Completion: 2025-08-14

Conditions

Schizophrenia

Interventions

DRUG

No Results Yet

NCT06299111 | RECRUITING | PHASE2

195 Participants

A Trial to Learn How Well REGN9933 and REGN7508 Work for Preventing Blood Clots, and How Safe They Are, in Adults Who Have a Peripherally Inserted Central Catheter (PICC)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-09-20

Completion: 2026-06-08

Conditions

Venous Thromboembolism

Interventions

DRUG

No Results Yet

NCT06271265 | RECRUITING | PHASE1

48 Participants

Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-03-29

Completion: 2027-01-31

Conditions

Postoperative Pain

Interventions

DRUG

No Results Yet

NCT06268730 | TERMINATED | NA

14 Participants

Effects of SinuSonic on Psychological and Physical Well-Being

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-04-08

Completion: 2025-04-15

Conditions

Nasal Congestion and Inflammations Sinus Congestion Chronic

Interventions

OTHER

No Results Yet

NCT06268704 | RECRUITING | PHASE4

230 Participants

Particulate vs. Non-Particulate Steroid for Sacroiliac Joint Injection

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-03-27

Completion: 2027-01-01

Conditions

Sacroiliac Joint Dysfunction Sacro-Iliac Spondylosis

Interventions

DRUG

No Results Yet

NCT06262178 | RECRUITING | NA

120 Participants

Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2025-07-21

Completion: 2026-05-31

Conditions

PTSD Depression Parent-Child Relations

Interventions

BEHAVIORAL

No Results Yet

NCT06249165 | ACTIVE_NOT_RECRUITING | PHASE4

130 Participants

VictORION-INCLUSION: Evaluating Inclisiran for Cholesterol Managment in Heart Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-12-16

Completion: 2026-12-31

Conditions

Atherosclerotic Cardiovascular Disease

Interventions

DRUG

No Results Yet

NCT06247995 | RECRUITING | PHASE1/PHASE2

58 Participants

A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-08-14

Completion: 2031-09-09

Conditions

Breast Cancer

Interventions

DRUG

No Results Yet

NCT06246916 | RECRUITING | PHASE3

560 Participants

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

Study Type: INTERVENTIONAL

Last Updated: 2025-11-06

Start Date: 2024-09-09

Completion: 2027-03-22

Conditions

Melanoma

Interventions

DRUG

No Results Yet