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Clinical Trials

Showing trials with last updates posted in 2024.

NCT05136417 | COMPLETED | NA
100 Participants

Study of Intra-Cardiac Echocardiography in Guiding Left Atrial Appendage Occlusion With the Watchman Device

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2022-01-04
Completion: 2023-12-15
Conditions
Left Atrial Appendage Occlusion
Interventions
DEVICE
Results Available
NCT05116709 | COMPLETED | PHASE1
28 Participants

Assessment of Safety and Preliminary Clinical Efficacy with BAT6005 in Advanced Malignant Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-11-12
Completion: 2024-01-10
Conditions
Locally Advanced or Metastatic Solid Tumors
Interventions
DRUG
No Results Yet
NCT05103904 | RECRUITING | PHASE2
19 Participants

Lenvatinib for the Treatment of Recurrent Hepatocellular Carcinoma After Liver Transplant

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2022-04-19
Completion: 2025-11-04
Conditions
Recurrent Hepatocellular Carcinoma Stage III Hepatocellular Carcinoma AJCC V8 Stage IIIA Hepatocellular Carcinoma AJCC V8 Stage IIIB Hepatocellular Carcinoma AJCC V8 Stage IV Hepatocellular Carcinoma AJCC V8 Stage IVA Hepatocellular Carcinoma AJCC V8 Stage IVB Hepatocellular Carcinoma AJCC V8 Unresectable Hepatocellular Carcinoma
Interventions
OTHER DRUG
No Results Yet
NCT05100251 | RECRUITING | PHASE1
90 Participants

Clinical Trial of WBC100 on Advanced Solid Tumor

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-10-25
Completion: 2025-10-25
Conditions
Solid Tumor
Interventions
DRUG
No Results Yet
NCT05094271 | RECRUITING | PHASE1
260 Participants

Is Obstructive Sleep Apnea Important in the Development of Alzheimer's Disease?

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-06-30
Completion: 2025-05-20
Conditions
OSA Sleep Apnea Obstructive Sleep Apnea Alzheimer Disease
Interventions
OTHER DEVICE
No Results Yet
NCT05073510 | COMPLETED
187 Participants

Clinical Evaluation of the BlueDop Vascular Expert for Assessing Peripheral Arterial Disease

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2021-10-11
Completion: 2023-09-11
Conditions
Peripheral Arterial Disease
Interventions
DEVICE
Results Available
NCT05072340 | COMPLETED | NA
203 Participants

Evaluation of Resilience Skills Enhancement (RISE) Training Among University Students

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-12-01
Completion: 2022-01-31
Conditions
Resilience, Psychological Adaptation, Psychological
Interventions
BEHAVIORAL
No Results Yet
NCT05067478 | COMPLETED
403 Participants

Composur: Study to Understand the Performance of Vibegron in Participants with Overactive Bladder (OAB)

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2021-10-28
Completion: 2024-07-22
Conditions
Overactive Bladder
Interventions
DRUG
No Results Yet
NCT05061095 | COMPLETED
51 Participants

Understanding What Matters Most to Patients: Establishing the Validity of a Best-Worst Scaling Survey

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2022-03-21
Completion: 2023-09-26
Conditions
Hematologic Neoplasms
Interventions
OTHER
Results Available
NCT05034952 | COMPLETED | PHASE2
303 Participants

A Study Evaluating Efficacy and Safety of VX-548 for Acute Pain After an Abdominoplasty

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-08-30
Completion: 2021-12-05
Conditions
Acute Pain
Interventions
DRUG
Results Available
NCT05024760 | RECRUITING | EARLY_PHASE1
150 Participants

Antiseptic Effects on the Dental Implant Internal Surface Microbiome

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2022-07-28
Completion: 2025-11-30
Conditions
Peri-Implantitis Peri-implant Mucositis Implant Infection Dental Implant Failed
Interventions
DRUG
No Results Yet
NCT05021640 | COMPLETED | PHASE1
36 Participants

Study of DCR-AUD in Healthy Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-09-21
Completion: 2022-12-31
Conditions
Alcohol Use Disorder (AUD)
Interventions
DRUG
Results Available
NCT05017012 | ACTIVE_NOT_RECRUITING | PHASE1
72 Participants

A Study to Evaluate the Bioavailability of Pembrolizumab (MK-3475) Via Subcutaneous (SC) Injection of Pembrolizumab Formulated With Berahyaluronidase Alfa (MK-5180) [MK-3475A] In Advanced Solid Tumors (MK-3475A-C18)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-09-21
Completion: 2026-09-26
Conditions
Advanced or Metastatic Solid Tumors
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT05002647 | COMPLETED
2601 Participants

Relationship Between the Clinical Pharmacist & Antibiotic Use by Using the Electronic Program

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2021-09-15
Completion: 2022-01-01
Conditions
Clinical Pharmacists Electronic Medical Record
Interventions
OTHER
No Results Yet
NCT05001009 | ENROLLING_BY_INVITATION | NA
72 Participants

Goals of Care Conversations Study

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2022-09-13
Completion: 2024-09-30
Conditions
Seriously Ill Patients Cancer Heart Failure Interstitial Lung Disease Chronic Obstructive Pulmonary Disease End-stage Renal Disease End-stage Liver Disease Dementia
Interventions
BEHAVIORAL
No Results Yet
NCT04992104 | RECRUITING
800 Participants

Microbiome and Malnutrition in Pregnancy

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2023-02-22
Completion: 2027-03-31
Conditions
Pregnancy Related Pregnancy Loss Pregnancy Complications Pregnancy; Parasitic Disease Microbial Colonization Microbial Disease Parasitic Disease Metabolomics Malnutrition Malnutrition, Infant Malnutrition Pregnancy Breast Feeding
No Results Yet
NCT04980248 | COMPLETED | PHASE1
15 Participants

Study of ALXN1850 in Participants With Hypophosphatasia (HPP)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-09-28
Completion: 2022-08-24
Conditions
Hypophosphatasia
Interventions
BIOLOGICAL
Results Available
NCT04972201 | COMPLETED
2305 Participants

A Proof of Concept Study of Pan-cancer Early Detection by Liquid Biopsy

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2021-06-01
Completion: 2022-03-31
Conditions
Cancer
Interventions
DEVICE
No Results Yet
NCT04971109 | COMPLETED | PHASE3
467 Participants

Safety, Tolerability and Pharmacokinetics of TPOXX When Administered Orally for 28 Days

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2022-03-29
Completion: 2023-05-12
Conditions
Smallpox
Interventions
DRUG OTHER
Results Available
NCT04969471 | RECRUITING | NA
148 Participants

NATURE (EnVast As an Adjunct PPCI in Subjects Presenting with STEMI)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-12-09
Completion: 2025-07-31
Conditions
Segment Elevation Myocardial Infarction (STEMI)
Interventions
DEVICE PROCEDURE
No Results Yet
NCT04948749 | RECRUITING | NA
792 Participants

Drug Eluting Stenting and Aggressive Medical Treatment for Preventing Recurrent Stroke in Intracranial Atherosclerotic Disease Trial

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-07-02
Completion: 2026-12-31
Conditions
ICAD - Intracranial Atherosclerotic Disease ICAS - Intracranial Atherosclerosis Drug-eluting Stent Stroke Drug Eluting Stents (DES) Medical Treatment
Interventions
DEVICE DRUG BEHAVIORAL
No Results Yet
NCT04937868 | RECRUITING
12000 Participants

Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2018-01-15
Completion: 2026-01-15
Conditions
Abdominal Injury Pelvic Fracture Genital Hemorrhage Lumbar Spine Injury Hip Injuries Liver Injury Spleen Injury Renal Injury Diaphragm Injury Aortic Rupture Aortic Dissection Bowel Disease Vascular System Injuries Sacral Fracture
Interventions
OTHER
No Results Yet
NCT04934176 | RECRUITING
125 Participants

3D Dynamic and Patient-Centered Outcomes of Facial Reanimation Surgery in Patients With Facial Paralysis

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2021-06-03
Completion: 2026-01-03
Conditions
Facial Paralysis
Interventions
OTHER
No Results Yet
NCT04930432 | RECRUITING | PHASE1/PHASE2
400 Participants

Study of MCLA-129, a Human Bispecific EGFR and cMet Antibody, in Patients With Advanced NSCLC and Other Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-09-24
Completion: 2028-04-30
Conditions
Solid Tumor Non-Small Cell Lung Cancer Head and Neck Cancer Colorectal Cancer
Interventions
DRUG
No Results Yet
NCT04913012 | COMPLETED | NA
150 Participants

Exercise Booster Sessions in People With Multiple Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-08-01
Completion: 2024-10-04
Conditions
Multiple Sclerosis
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT04908410 | ACTIVE_NOT_RECRUITING
1650 Participants

The Norwegian Addiction, Pain and Trauma Study

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2021-03-23
Completion: 2024-06-02
Conditions
Chronic Pain Post-traumatic Stress Disorder Substance Use Disorders
No Results Yet
NCT04907929 | COMPLETED | NA
9 Participants

Effectiveness Speech and Cognitive Therapy Implant Pre-cohlear Implantation

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-12-15
Completion: 2024-12-15
Conditions
Cochlear Implants
Interventions
BEHAVIORAL
No Results Yet
NCT04898777 | COMPLETED | NA
100 Participants

EUS-Guided Choledochoduodenostomy Versus ERCP for Primary Biliary Decompression in Distal Malignant Biliary Obstruction

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-07-01
Completion: 2024-07-01
Conditions
Malignant Biliary Obstruction
Interventions
PROCEDURE
No Results Yet
NCT04892433 | RECRUITING
150 Participants

Tissue Study in Patients Undergoing CAR-T Cell Therapy (CAR_21_01)

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2021-05-14
Completion: 2025-04-30
Conditions
CAR-T Therapy Complications
No Results Yet
NCT04890171 | RECRUITING | NA
708 Participants

Comparison of Endoscopic Resection and Surgery for Early Gastric Cancer With Undifferentiated Histological Type

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-06-11
Completion: 2028-02-28
Conditions
Stomach Cancer Undifferentiated Type Expanded Indication of Endoscopic Resection
Interventions
PROCEDURE
No Results Yet
NCT04871568 | RECRUITING | NA
100 Participants

Central Vein Stenosis Due to Dialysis Catheter Insertion in Subclavian Compared to Jugular Vein

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-11-15
Completion: 2025-09-30
Conditions
Subclavian Vein Stenosis Jugular Vein Occlusion
Interventions
PROCEDURE
No Results Yet
NCT04840355 | RECRUITING
100 Participants

Multi-Centre, Prospective, Non-Interventional Study to Intensively Monitor the Safety of Sintilimab in Clinical Practice Among Chinese Patients

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2021-02-26
Completion: 2025-11-14
Conditions
Immune Related Adverse Events PD-1
Interventions
DRUG
No Results Yet
NCT04831320 | ACTIVE_NOT_RECRUITING | PHASE2
46 Participants

Nab-Paclitaxel in Combination With Nivolumab to Treat Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma That Progressed on a PD-1 or PD-L1 Inhibitor

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-09-28
Completion: 2025-12-31
Conditions
Metastatic Head-and-neck Squamous-cell Carcinoma
Interventions
DRUG
No Results Yet
NCT04827875 | COMPLETED | PHASE1
25 Participants

Safety and Efficacy of AIV001 on Scar Formation and Keloid Recurrence Following Keloidectomy

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-06-23
Completion: 2022-12-15
Conditions
Keloid Scar Incision Excision Margin
Interventions
DRUG
No Results Yet
NCT04823689 | COMPLETED | NA
120 Participants

Reduction of Anterior Glenohumeral Dislocation in Ventral Decubitus Versus Dorsal Decubitus Under Procedural Sedation

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-07-21
Completion: 2024-02-10
Conditions
Reduction Emergencies Anterior Shoulder Dislocation
Interventions
PROCEDURE
No Results Yet
NCT04816227 | RECRUITING
180 Participants

Expression Profile Study of Macrophages From Patients Affected by ALS or Other Related Motor Impairments

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2021-09-29
Completion: 2026-10-30
Conditions
Amyotrophic Lateral Sclerosis
No Results Yet
NCT04813055 | RECRUITING
510 Participants

Prospective Registry Of Therapeutic EndoscopiC ulTrasound

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2020-12-01
Completion: 2025-12-01
Conditions
Gastric Outlet Obstruction Biliary Obstruction Acute Pancreatic Fluid Collection Acute Pancreatitis With Infected Necrosis Acute Cholecystitis Chronic Pancreatitis
Interventions
PROCEDURE
No Results Yet
NCT04807777 | TERMINATED | PHASE2
3 Participants

Study of Ruxolitinib in Solid Organ Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2022-04-07
Completion: 2023-04-04
Conditions
Advanced Cutaneous Squamous Cell Carcinoma
Interventions
DRUG
Results Available
NCT04802967 | COMPLETED | PHASE1
141 Participants

A Study on Ketoprofen Lysine Salt (KLS) + Gabapentin (GABA) vs KLS to Investigate Their Pharmacodynamic in Healthy Males

Study Type: INTERVENTIONAL
Last Updated: 2024-12-27
Start Date: 2021-02-08
Completion: 2022-03-30
Conditions
No Condition
Interventions
DRUG OTHER
Results Available
NCT04795245 | COMPLETED
805 Participants

Non-interventional Study for Real-world Data of Afatinib Treatment in First-line Setting and of Subsequent Therapies for Patients With Advanced Epidermal Growth Factor Receptor (EGFR) Mutation-positive Lung Adenocarcinoma

Study Type: OBSERVATIONAL
Last Updated: 2024-12-27
Start Date: 2021-08-26
Completion: 2023-10-16
Conditions
Non-squamous, Non-Small Cell Lung Cancer
Interventions
DRUG
Results Available
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