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Clinical Trials

Showing trials with last updates posted in 2024.

NCT04861584 | RECRUITING | PHASE2
41 Participants

Neoadjuvant Toripalimab in Combination with Gemcitabine and Cisplatin Therapy in Local Advanced Bladder Cancer Subjects

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2021-06-03
Completion: 2026-10-03
Conditions
Urinary Bladder Cancer
Interventions
DRUG
No Results Yet
NCT04843488 | COMPLETED | NA
30 Participants

Effectiveness of Different Membrane Applications in Vertical Ridge Augmentation

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2021-04-15
Completion: 2022-11-12
Conditions
Bone Regeneration Dental Implants Polytetrafluoroethylene
Interventions
PROCEDURE
No Results Yet
NCT04795531 | COMPLETED | PHASE3
588 Participants

A Research Study to Compare Two Types of Insulin, a New Insulin, Insulin Icodec and an Available Insulin, Insulin Degludec, in People With Type 2 Diabetes Who Have Not Used Insulin Before (ONWARDS 3)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2021-03-24
Completion: 2022-06-23
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
Results Available
NCT04792190 | COMPLETED | PHASE4
25 Participants

Use of Dapagliflozin to Reduce Burden of Atrial Fibrillation in Patients Undergoing Catheter Ablation of Symptomatic Atrial Fibrillation

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2021-07-27
Completion: 2023-03-31
Conditions
Atrial Fibrillation
Interventions
DRUG
Results Available
NCT04779099 | COMPLETED | NA
60 Participants

Trial of a Brief Psychological Intervention for Suicidal Patients with Borderline Personality Disorder in the Emergency Department

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2021-10-22
Completion: 2023-05-24
Conditions
Borderline Personality Disorder Suicide and Self-harm
Interventions
BEHAVIORAL
No Results Yet
NCT04746417 | RECRUITING
70 Participants

Assessment of Skeletal Maturity Using Proximal Femoral Epiphysis in Patients With Scoliosis

Study Type: OBSERVATIONAL
Last Updated: 2024-12-04
Start Date: 2021-02-01
Completion: 2025-12-31
Conditions
Idiopathic Scoliosis
No Results Yet
NCT04708535 | ENROLLING_BY_INVITATION
50 Participants

Adaptive Immune Response in Visceral and Subcutaneous Fat: Role in Human Insulin Resistance

Study Type: OBSERVATIONAL
Last Updated: 2024-12-04
Start Date: 2017-08-01
Completion: 2025-08-31
Conditions
Insulin Resistance Insulin Sensitivity Obesity Inflammation
No Results Yet
NCT04696146 | COMPLETED | PHASE1/PHASE2
45 Participants

Berinert (C1INH) vs Placebo for DGF/IRI

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2021-03-03
Completion: 2022-07-31
Conditions
End Stage Renal Disease Chronic Kidney Diseases
Interventions
DRUG
Results Available
NCT04683913 | COMPLETED | NA
20 Participants

Telerehabilitation Gait Modification

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2021-01-01
Completion: 2022-05-20
Conditions
Osteoarthritis, Knee
Interventions
BEHAVIORAL OTHER
Results Available
NCT04682665 | COMPLETED
81 Participants

Prebiotic Effect of Eicosapentaenoic Acid Treatment for Colorectal Cancer Liver Metastases

Study Type: OBSERVATIONAL
Last Updated: 2024-12-04
Start Date: 2021-09-16
Completion: 2024-07-31
Conditions
Colon Cancer Liver Metastasis
Interventions
DRUG OTHER
No Results Yet
NCT04675827 | TERMINATED | PHASE2
139 Participants

De-escalation Adjuvant Chemo in HER2+/ER-/node-neg Early BC Patients Who Achieved PCR After Neoadjuvant Chemo & Dual HER2 Blockade

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2022-01-17
Completion: 2024-11-26
Conditions
HER2-positive Breast Cancer ER-Negative Breast Cancer PR-Negative Breast Cancer Node-negative Breast Cancer
Interventions
DRUG
No Results Yet
NCT04615546 | RECRUITING | NA
60 Participants

Role of Nutrient Transit in Hyperinsulinemic Hypoglycemia

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-05-06
Completion: 2025-12-31
Conditions
Post-Bariatric Hypoglycemia
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT04576494 | COMPLETED | NA
4 Participants

Study of the Functional Effects of Nusinersen in 5q-spinal Muscular Amyotrophy Adults (SMA Type 2 or 3 Forms)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2022-01-24
Completion: 2023-01-24
Conditions
Spinal Muscular Atrophy
Interventions
OTHER DRUG
No Results Yet
NCT04562311 | ACTIVE_NOT_RECRUITING | PHASE2
45 Participants

Chidamide With Immunotherapy for Patients With Locally Advanced or Metastatic Urothelial Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2021-01-01
Completion: 2024-08-30
Conditions
Bladder Cancer Stage IV
Interventions
DRUG
No Results Yet
NCT04551495 | ACTIVE_NOT_RECRUITING | PHASE2
65 Participants

Neoadjuvant Study of Targeting ROS1 in Combination With Endocrine Therapy in Invasive Lobular Carcinoma of the Breast (ROSALINE)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2021-01-14
Completion: 2025-01-31
Conditions
Invasive Lobular Breast Carcinoma ER+ Breast Cancer HER2-negative Breast Cancer
Interventions
DRUG
No Results Yet
NCT04548973 | COMPLETED | PHASE4
600 Participants

A Multicenter Study of the Efficacy and Safety of Esketamine for Analgesia During Cesarean Section

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2021-09-18
Completion: 2022-09-20
Conditions
Fetal or Neonatal Effect of Damage to Placenta From Caesarean Section
Interventions
DRUG
No Results Yet
NCT04519931 | COMPLETED | NA
60 Participants

The Effect of Stress Ball Used During Endoscopy

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-11-05
Completion: 2021-03-04
Conditions
Pain Anxiety Satisfaction
Interventions
OTHER
No Results Yet
NCT04518501 | RECRUITING | PHASE1/PHASE2
50 Participants

Fuzuloparib Arsenic Trioxide Platinum Resistance Relapsed Ovarian Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-07-01
Completion: 2024-12-03
Conditions
Efficacy and Safety
Interventions
DRUG
No Results Yet
NCT04513808 | RECRUITING | PHASE3
1614 Participants

Total Intravenous Anesthesia and Recurrence Free Survival

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-08-15
Completion: 2025-12-31
Conditions
Esophageal Cancer
Interventions
DRUG
No Results Yet
NCT04512573 | COMPLETED
232 Participants

Patient Outcomes: Real World Evidence in Rheumatoid Arthritis (POWER)

Study Type: OBSERVATIONAL
Last Updated: 2024-12-04
Start Date: 2020-05-21
Completion: 2022-08-31
Conditions
Patient Outcomes: Real World Evidence in Rheumatoid Arthritis (POWER)
No Results Yet
NCT04504955 | ENROLLING_BY_INVITATION
10000 Participants

CorEvitas Atopic Dermatitis Registry: a Study of Post Approval Drug Safety and Effectiveness

Study Type: OBSERVATIONAL
Last Updated: 2024-12-04
Start Date: 2020-07-14
Completion: 2100-12-31
Conditions
Atopic Dermatitis
Interventions
OTHER
No Results Yet
NCT04445909 | RECRUITING
30 Participants

Validation of Continuous Transcutaneous Carbon Dioxide Monitoring in VA-ECMO Patients

Study Type: OBSERVATIONAL
Last Updated: 2024-12-04
Start Date: 2019-11-18
Completion: 2025-01-31
Conditions
Carbon Dioxide
Interventions
DEVICE
No Results Yet
NCT04443088 | ACTIVE_NOT_RECRUITING | PHASE1
78 Participants

An Open-Label Study of INV-1120 As a Single Agent and in Combination with Pembrolizumab in Adult Patients with Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-06-26
Completion: 2026-03-31
Conditions
Cancer Solid Tumor, Adult Cancer Metastatic Solid Carcinoma Solid Tumor, Unspecified, Adult Tumor, Solid
Interventions
DRUG COMBINATION_PRODUCT
No Results Yet
NCT04401462 | RECRUITING | NA
68 Participants

Scandinavian Olecranon Research in the Elderly

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-10-05
Completion: 2027-12-31
Conditions
Olecranon Fracture
Interventions
PROCEDURE BEHAVIORAL
No Results Yet
NCT04378153 | COMPLETED
987 Participants

Impact of Discontinuing Chronic Therapies in People With Cystic Fibrosis on Highly Effective CFTR Modulator Therapy

Study Type: OBSERVATIONAL
Last Updated: 2024-12-04
Start Date: 2020-08-25
Completion: 2022-07-11
Conditions
Cystic Fibrosis
Results Available
NCT04375527 | TERMINATED | PHASE2
3 Participants

Binimetinib and Nivolumab for the Treatment of Locally Advanced Unresectable or Metastatic BRAF V600 Wildtype Melanoma

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-12-03
Completion: 2024-11-22
Conditions
Clinical Stage III Cutaneous Melanoma AJCC V8 Clinical Stage IV Cutaneous Melanoma AJCC V8 Locally Advanced Cutaneous Melanoma Metastatic Cutaneous Melanoma Pathologic Stage III Cutaneous Melanoma AJCC V8 Pathologic Stage IIIA Cutaneous Melanoma AJCC V8 Pathologic Stage IIIB Cutaneous Melanoma AJCC V8 Pathologic Stage IIIC Cutaneous Melanoma AJCC V8 Pathologic Stage IIID Cutaneous Melanoma AJCC V8 Pathologic Stage IV Cutaneous Melanoma AJCC V8 Unresectable Cutaneous Melanoma
Interventions
DRUG BIOLOGICAL OTHER
No Results Yet
NCT04364555 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
90 Participants

Efficacy of Topical Treatment With Clobetasol in Symptomatic Oral Lichen Planus.

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-05-18
Completion: 2024-07-03
Conditions
Oral Lichen Planus
Interventions
DRUG
No Results Yet
NCT04362306 | COMPLETED | NA
89 Participants

Radiation Oncology Patient Medical Physics Intervention Study

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-03-03
Completion: 2024-06-28
Conditions
Anxiety Patient Satisfaction Radiation Therapy
Interventions
BEHAVIORAL
No Results Yet
NCT04351594 | COMPLETED | PHASE2/PHASE3
70 Participants

Biofreeze and the Effect on Knee Osteoarthritis

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-11-01
Completion: 2024-01-01
Conditions
Knee Osteoarthritis
Interventions
DRUG OTHER
No Results Yet
NCT04321005 | COMPLETED
973 Participants

Surgical Safety and Effectiveness in Orthopedics: Swiss-wide Multicenter Evaluation and Prediction of Core Outcomes in Arthroscopic Rotator Cuff Reconstruction

Study Type: OBSERVATIONAL
Last Updated: 2024-12-04
Start Date: 2020-06-01
Completion: 2023-12-21
Conditions
Rotator Cuff Tear
Interventions
PROCEDURE
No Results Yet
NCT04289779 | ACTIVE_NOT_RECRUITING | PHASE2
46 Participants

Study of CAbozantinib in Combination with AtezolizumaB for Muscle-Invasive BladdEr Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-05-21
Completion: 2025-06-30
Conditions
Bladder Cancer
Interventions
DRUG PROCEDURE
No Results Yet
NCT04273165 | COMPLETED | PHASE2
30 Participants

Safety and Efficacy of Etravirine in Friedreich Ataxia Patients

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-09-17
Completion: 2023-01-17
Conditions
Friedreich Ataxia
Interventions
DRUG
No Results Yet
NCT04207320 | TERMINATED | NA
3 Participants

Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) for Patients With Severe Sickle Cell Disease

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2020-04-07
Completion: 2023-05-22
Conditions
Sickle Cell Disease
Interventions
DEVICE
Results Available
NCT04188951 | COMPLETED | EARLY_PHASE1
10 Participants

HFHS-1801-A Pilot Study of Immunotherapy As Consolidation Therapy for Patients with Recurrent Head and Neck Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2019-10-04
Completion: 2023-06-15
Conditions
Head and Neck Neoplasms
Interventions
DRUG
No Results Yet
NCT04182685 | COMPLETED
410 Participants

Evaluation of Medical Conditions Associated With Zika Virus Infection in Managua, Nicaragua

Study Type: OBSERVATIONAL
Last Updated: 2024-12-04
Start Date: 2019-10-01
Completion: 2020-12-31
Conditions
Zika Virus
No Results Yet
NCT04172766 | RECRUITING
300000 Participants

Apple Hearing Study

Study Type: OBSERVATIONAL
Last Updated: 2024-12-04
Start Date: 2019-11-14
Completion: 2029-08-31
Conditions
Hearing Loss, Noise-Induced Hearing Loss Tinnitus
No Results Yet
NCT04122378 | COMPLETED | NA
29 Participants

Acupuncture for Pain in Sickle Cell Disease

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2018-10-23
Completion: 2020-08-01
Conditions
Sickle Cell Disease
Interventions
OTHER
No Results Yet
NCT04106115 | RECRUITING | PHASE1/PHASE2
64 Participants

DURvalumab in Combination With S-488210/S-488211 vAccine in Non-muscle Invasive Bladder CancEr

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2022-03-25
Completion: 2025-05-31
Conditions
Bladder Cancer
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT04103242 | COMPLETED
23 Participants

Abundance of Lactobacillus in Endometrium Affected by Chronic Endometritis

Study Type: OBSERVATIONAL
Last Updated: 2024-12-04
Start Date: 2018-01-02
Completion: 2020-02-12
Conditions
Non Specific Chronic Endometritis Infertility, Female
Interventions
OTHER
No Results Yet
NCT04098705 | WITHDRAWN | NA
0 Participants

Emergency Department Triage in a Resource Constrained Setting: Application of the World Health Organization Triage Scale in Regional Papua New Guinea

Study Type: INTERVENTIONAL
Last Updated: 2024-12-04
Start Date: 2019-08-30
Completion: 2019-12-30
Conditions
Emergencies
Interventions
OTHER
No Results Yet
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