Molecular HistoMx Assessment for Kidney Transplant Rejection and Management
NCT ID: NCT07347353
Last Updated: 2026-01-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
400 participants
OBSERVATIONAL
2020-02-01
2024-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Kidney transplant recipients from two referral academic center were enrolled in the study
No intervention
No intervention
Interventions
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No intervention
No intervention
Eligibility Criteria
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Inclusion Criteria
* Patients receiving a kidney transplant from a living or brain-dead donor
Exclusion Criteria
* Patients without available graft biopsy material for molecular HistoMx testing
18 Years
ALL
No
Sponsors
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Paris Translational Research Center for Organ Transplantation
OTHER
Responsible Party
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Principal Investigators
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Carmen Lefaucheur
Role: PRINCIPAL_INVESTIGATOR
Paris Translational Research Center for Organ Transplantation
Alexandre Loupy
Role: PRINCIPAL_INVESTIGATOR
Paris Translational Research Center for Organ Transplantation
Locations
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Paris Bichat university hospital
Paris, , France
Paris Saint Louis University hospital
Paris, , France
Countries
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References
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Giarraputo A, Goutaudier V, Robin B, Angelini A, Sablik M, Aubert O, Rosales IA, Smith RN, Roufosse C, Adam B, Haas M, Colvin RB, Lefaucheur C, Mengel M, Zielinski D, Loupy A. Relevance of the Banff Human Organ Transplant Consensus Gene Panel for Detecting Antibody and T-Cell-Mediated Rejection of Kidney Allografts. Kidney Int Rep. 2024 May 4;9(7):2290-2294. doi: 10.1016/j.ekir.2024.04.054. eCollection 2024 Jul. No abstract available.
Zielinski D, Goutaudier V, Sablik M, Divard G, Aubert O, Piedrafita A, Mezine F, Dagobert J, Certain A, Robin B, Gueguen J, Rabant M, Duong van Huyen JP, Sannier A, Randoux-Lebrun C, Maanaoui M, Lionet A, Gibier JB, Gnemmi V, Le Quintrec M, Chauveau B, Vermorel A, Couzi L, Bestard O, Elias M, Louis K, Rosales IA, Smith RN, Kung VL, Anglicheau D, Legendre C, Del Bello A, Huang E, Adam B, Kamar N, Colvin RB, Mengel M, Lefaucheur C, Loupy A. Molecular diagnosis of kidney allograft rejection based on the Banff Human Organ Transplant gene panel: A multicenter international study. Am J Transplant. 2025 Aug;25(8):1631-1642. doi: 10.1016/j.ajt.2025.04.025. Epub 2025 May 8.
Other Identifiers
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Molecular_kidney rejection
Identifier Type: -
Identifier Source: org_study_id
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