Comparison of Quadratus Lumborum and Combined Groin Nerve Blocks for Postoperative Analgesia After Open Inguinal Hernia Repair.

NCT ID: NCT07343570

Last Updated: 2026-01-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

PHASE3

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-01-28

Study Completion Date

2026-12-30

Brief Summary

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This double-blind randomized controlled trial aimes to compares two ultrasound-guided regional techniques-lateral quadratus lumborum block versus combined ilio-inguinal/ilio-hypogastric/genitofemoral (II-IH-GFN) block-for postoperative analgesia after elective unilateral open inguinal hernia repair under spinal anesthesia in adults.

Detailed Description

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Conditions

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Postoperative Analgesia of Inguinal Hernia Repair in Adults

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Group 1 (Quadratus lumborum block)

Ultrasound-guided lateral quadratus lumborum block. Local anesthetic: 30 ml of (Ropivacaine 0.2%) is injected at the appropriate fascial level.

Group Type ACTIVE_COMPARATOR

Ultrasound-guided lateral quadratus lumborum block

Intervention Type PROCEDURE

Ultrasound-guided lateral quadratus lumborum block. Local anesthetic: 30 ml of (Ropivacaine 0.2%) is injected at the appropriate fascial level.

Group 2 ( Ilio-inguinal and ilio-hypogastric block)

Ultrasound-guided ilio-inguinal and ilio-hypogastric block. Local anesthesia: 20 ml of 0.2% ropivacaine for ilio-inguinal and ilio-hypogastric block + 10 ml of 0.2% ropivacaine for genitofemoral anaesthesia, total injection volume = 30 ml.

Group Type ACTIVE_COMPARATOR

Combined ilio-inguinal/ilio-hypogastric/genitofemoral (II-IH-GFN) block

Intervention Type PROCEDURE

Ultrasound-guided ilio-inguinal and ilio-hypogastric block. Local anesthesia: 20 ml of 0.2% ropivacaine for ilio-inguinal and ilio-hypogastric block + 10 ml of 0.2% ropivacaine for genitofemoral anaesthesia, total injection volume = 30 ml.

Interventions

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Ultrasound-guided lateral quadratus lumborum block

Ultrasound-guided lateral quadratus lumborum block. Local anesthetic: 30 ml of (Ropivacaine 0.2%) is injected at the appropriate fascial level.

Intervention Type PROCEDURE

Combined ilio-inguinal/ilio-hypogastric/genitofemoral (II-IH-GFN) block

Ultrasound-guided ilio-inguinal and ilio-hypogastric block. Local anesthesia: 20 ml of 0.2% ropivacaine for ilio-inguinal and ilio-hypogastric block + 10 ml of 0.2% ropivacaine for genitofemoral anaesthesia, total injection volume = 30 ml.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Adults aged 18-75 years.
* ASA physical status I-III.
* Scheduled for elective unilateral open inguinal hernia repair under standardized spinal anesthesia.
* Able to understand and use the Visual Analogue Scale (VAS).
* Provided written informed consent.

Exclusion Criteria

* Allergy to local anesthetics.
* Coagulopathy or current use of anticoagulants contraindicating peripheral nerve blocks.
* Infection at the injection site.
* Chronic opioid use (daily opioids \>2 weeks) or chronic pain syndromes.
* Body mass index (BMI) \>40 kg/m².
* Conversion to other surgery or bilateral repair.
* Pregnant patients.
* Refusal to sign informed consent.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Benha University

OTHER

Sponsor Role collaborator

Al-Azhar University

OTHER

Sponsor Role lead

Responsible Party

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Neveen Abd El Maksoad Kohaf

Lecturer of Clinical Pharmacy

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Al Azhar University

Cairo, Egypt, Egypt

Site Status

Countries

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Egypt

Central Contacts

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Neveen A. Kohaf, Ph.D

Role: CONTACT

01060383012

Facility Contacts

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Neveen Kohaf, Ph.D

Role: primary

01060383012

Other Identifiers

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RC. 12.9.2025

Identifier Type: -

Identifier Source: org_study_id

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