Ultrasound-Based Airway Assessment for Predicting Difficult Intubation in Adult Female Patients

NCT ID: NCT07343557

Last Updated: 2026-01-15

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 400 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-05-15
• Study Completion Date: 2025-12-15

Brief Summary

This prospective observational study aims to evaluate the ability of selected ultrasonographic airway measurements to predict difficult intubation in adult female patients undergoing elective surgery. Pre-induction airway ultrasonography will be performed to measure tongue thickness and anterior neck soft tissue-related parameters. These measurements will be compared with laryngoscopic findings during direct laryngoscopy. The results of this study may help identify practical and reliable ultrasound-based markers for preoperative airway assessment and improve patient safety.

Detailed Description

This is a prospective, single-center observational study conducted in adult female patients scheduled for elective surgery under general anesthesia. The study was performed at the University of Health Sciences Adana City Training and Research Hospital after approval by the institutional ethics committee.

Before induction of anesthesia, standardized ultrasonographic airway assessments were performed by an experienced anesthesiologist. Measurements included tongue thickness, the distance from the skin to the anterior commissure of the vocal cords, the distance from the skin to the hyoid bone, and the distance from the skin to the epiglottis. All measurements were obtained under static pre-induction conditions using portable ultrasound equipment.

Following anesthesia induction, direct laryngoscopy was performed, and laryngoscopic view was graded according to the Cormack-Lehane classification. Difficult intubation was defined based on predefined laryngoscopic criteria. Ultrasonographic measurements were then analyzed for their diagnostic performance in predicting difficult intubation.

The primary objective of the study was to determine the most informative ultrasonographic parameter for predicting difficult intubation in this population. Secondary objectives included comparing the relative diagnostic value of different ultrasound measurements and evaluating their potential role in routine preoperative airway assessment.

Conditions

Difficult Intubation; Airway Assessment

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Airway Ultrasound Assessment Cohort

Adult female patients undergoing elective surgery in whom preoperative airway ultrasonography was performed for observational assessment of airway anatomy. No intervention was assigned as part of the study.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Female patients aged 18-65 years
• American Society of Anesthesiologists (ASA) physical status I-III physical status I-III
• Scheduled for elective surgery under general anesthesia requiring tracheal intubation
• Ability to provide informed consent

Exclusion Criteria

• Body mass index ≥30 kg/m²
• Known history of difficult intubation
• Anatomical airway abnormalities or head and neck pathology
• Pregnancy
• Emergency surgery

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Adana City Training and Research Hospital

OTHER

Sponsor Role: lead

Responsible Party

Uğur serkan Çitilcioğlu

Anesthesiologist

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Adana City Training and Research Hospital

Adana, Adana, Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

ADN-USG-AIRWAY-2025

Identifier Type: -

Identifier Source: org_study_id