Effect of Ultrasound-Guided Quadro-Iliac Plane Block on Postoperative Analgesia After Lumbar Spinal Surgery

NCT ID: NCT07326774

Last Updated: 2026-01-12

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 60 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2026-01-01
• Study Completion Date: 2026-09-30

Brief Summary

This prospective observational study aims to evaluate the effect of ultrasound-guided Quadro-Iliac Plane Block (QIPB) on postoperative analgesia in patients undergoing lumbar spinal surgery. Lumbar spinal procedures are commonly associated with significant postoperative pain, which may impair early mobilization and increase opioid consumption. In routine clinical practice, QIPB is increasingly used as part of multimodal analgesia to improve pain control and reduce opioid-related adverse effects.

Adult patients scheduled for elective lumbar spinal surgery under general anesthesia will be followed according to routine clinical care. Postoperative analgesia will be managed with intravenous patient-controlled analgesia (PCA) using tramadol, with or without the addition of ultrasound-guided QIPB, based on the preference of the attending anesthesiologist. No intervention or treatment assignment will be performed by the investigators.

Postoperative pain scores at rest and during movement, opioid consumption, need for rescue analgesics, incidence of nausea and vomiting, and patient satisfaction will be recorded during the first 24 hours after surgery. The findings of this study are expected to provide further clinical evidence regarding the effectiveness of QIPB as part of multimodal analgesia in lumbar spinal surgery.

Detailed Description

This is a single-center, prospective observational cohort study conducted in patients undergoing elective lumbar spinal surgery under general anesthesia. The study is designed to assess the effects of ultrasound-guided Quadro-Iliac Plane Block (QIPB) on postoperative analgesia when used as part of routine multimodal pain management.

Eligible patients aged 18-65 years with American Society of Anesthesiologists (ASA) physical status I-III and a body mass index below 35 kg/m² will be included after providing written informed consent. All patients will receive standardized general anesthesia and postoperative intravenous patient-controlled analgesia (PCA) with tramadol as part of routine care. The decision to perform QIPB will be made by the attending anesthesiologist according to clinical judgment and routine practice, without any intervention or assignment by the research team.

Ultrasound-guided QIPB, when applied, will be performed bilaterally under sterile conditions in the prone position at the end of surgery. Patients will be observed in two cohorts: those receiving PCA alone and those receiving PCA in combination with QIPB.

Postoperative outcomes will be assessed in the post-anesthesia care unit and at 1, 6, 12, and 24 hours postoperatively. Pain intensity will be evaluated using the Numeric Rating Scale (NRS) at rest and during movement. Secondary outcomes will include total opioid consumption, time to first rescue analgesic requirement, incidence of postoperative nausea and vomiting, sedation level, and patient satisfaction assessed using a 5-point Likert scale at 24 hours. Any block-related complications will also be recorded.

Data will be analyzed using appropriate statistical methods to compare postoperative analgesic outcomes between the two cohorts. This observational study aims to reflect real-world clinical practice and contribute to the growing evidence on the role of QIPB in postoperative pain management after lumbar spinal surgery.

Conditions

Postoperative Pain; Lumbar Spine Surgery; Postoperative Analgesia

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

PCA + QIPB Group

Patients who receive standard postoperative intravenous patient-controlled analgesia (PCA) with tramadol in combination with ultrasound-guided Quadro-Iliac Plane Block (QIPB) as part of routine clinical care following lumbar spinal surgery.

QIPB

Intervention Type: OTHER

Quadro-Iliac Plane Block using local anesthetic.

PCA Only Group

Patients who receive standard postoperative intravenous patient-controlled analgesia (PCA) with tramadol alone without the addition of any regional analgesic block following lumbar spinal surgery.

No interventions assigned to this group

Interventions

QIPB

Quadro-Iliac Plane Block using local anesthetic.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Patients aged between 18 and 65 years
• American Society of Anesthesiologists (ASA) physical status I-III
• Body mass index (BMI) <35 kg/m²
• Scheduled for elective posterior lumbar spinal instrumentation surgery under general anesthesia

Exclusion Criteria

• Refusal to participate in the study
• Emergency surgery
• Local infection or hematoma at the block application site
• Previous surgery at the block application site
• Presence of coagulopathy
• Known allergy or toxicity to local anesthetics
• History of hematological, renal, or hepatic disease, or advanced respiratory or cardiac failure
• Chronic analgesic use, chronic alcohol consumption, or substance abuse
• Inability to speak Turkish or presence of language/communication barriers

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Fatih Sultan Mehmet Training and Research Hospital

OTHER

Sponsor Role: lead

Responsible Party

Elif Acar Değer

Dr

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Oznur Demiroluk, Assoc. Prof.

Role: PRINCIPAL_INVESTIGATOR

Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Türkiye

Locations

Fatih Sultan Mehmet Training and Research Hospital

Istanbul, Istanbul, Turkey (Türkiye)

Countries

Turkey (Türkiye)

Central Contacts

Elif Acar Deger, Dr.

Role: CONTACT

drelifacardeger@gmail.com

+905069435510

Facility Contacts

Elif Acar Deger, MD

Role: primary

drelifacardeger@gmail.com

+90 506 943 55 10

Other Identifiers

2025/397

Identifier Type: -

Identifier Source: org_study_id