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Effect of the Quadratus Lumborum Block Versus the Lumbar Plexus for Spiral Thighplasty Surgery

NCT ID: NCT07280182

Last Updated: 2025-12-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-11-27

Study Completion Date

2026-02-10

Brief Summary

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Whether trans muscular QLB provides postoperative analgesia compared with LPB after thigh lift surgery

Detailed Description

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Adequate analgesia after spiral thigh reduction (thigh lift) is essential for early mobilization and patient satisfaction. Quadratus lumborum block (QLB) has shown analgesic efficacy comparable to lumbar plexus block (LPB) for hip area surgery with potential advantages in motor-sparing and safety

Conditions

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Analgesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Prospective, randomized, parallel-group, double-blind, clinical trial. Primary endpoint: time for first analgesic request postoperatively. Key secondary endpoints: 24-hour opioid consumption (oral morphine equivalents), pain on movement at 6/12/24 hours, time to first ambulation, postoperative nausea/vomiting (PONV), block performance time, and block-related complications. Hypothesis: QLB is non-inferior to LPB for 24-hour pain scores and will yield less motor weakness
Primary Study Purpose

OTHER

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors
Computer-generated randomization in variable blocks; allocation sealed in opaque envelopes. Blocks performed by an anesthesiologist not involved in postoperative assessment. Patients and outcome assessors are blinded. Drape and opaque dressings conceal injection sites for both groups to preserve blinding

Study Groups

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Group QLB

Ultrasound-Guided Trans-muscular QLB

Group Type OTHER

Ultrasound-Guided Trans-muscular QLB

Intervention Type OTHER

With the patient lateral decubitus position, a low-frequency curvilinear probe in the 'Shamrock' view at L2-L4. In-plane posterior-to-anterior needle advancement through the Quadratus lumborum to the interfascial plane anterior to QL and posterior to Psoas major. Inject 30 mL Bupivacaine 0.25% after negative aspiration and hydrodissection to confirm proper spread . Then the patient will be turned to the other side, and the block will be done with the same technique

Group LPB

Ultrasound-Guided Posterior Lumbar Plexus (Psoas Compartment) Block

Group Type OTHER

Ultrasound-Guided Posterior Lumbar Plexus (Psoas Compartment) Block

Intervention Type OTHER

Lateral decubitus, Shamrock view to identify the Psoas compartment; in-plane needle advancement to the Psoas compartment adjacent to the transverse process. Inject 30 mL of Bupivacaine 0.25% in 5 mL increments, aspirating frequently. This will be done in the same position for both sides

Interventions

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Ultrasound-Guided Trans-muscular QLB

With the patient lateral decubitus position, a low-frequency curvilinear probe in the 'Shamrock' view at L2-L4. In-plane posterior-to-anterior needle advancement through the Quadratus lumborum to the interfascial plane anterior to QL and posterior to Psoas major. Inject 30 mL Bupivacaine 0.25% after negative aspiration and hydrodissection to confirm proper spread . Then the patient will be turned to the other side, and the block will be done with the same technique

Intervention Type OTHER

Ultrasound-Guided Posterior Lumbar Plexus (Psoas Compartment) Block

Lateral decubitus, Shamrock view to identify the Psoas compartment; in-plane needle advancement to the Psoas compartment adjacent to the transverse process. Inject 30 mL of Bupivacaine 0.25% in 5 mL increments, aspirating frequently. This will be done in the same position for both sides

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ASA ( American Society of Anaesthesia) I-II
* elective bilateral spiral thigh lift under general anesthesia
* consent to regional block and trial participation

Exclusion Criteria

* Coagulopathy or therapeutic anticoagulation not meeting ASRA safety windows
* infection at injection sites
* allergy to local anesthetics
* preexisting significant neuropathy
* BMI \> 35 kg/m² if impeding ultrasound visualization; renal/hepatic failure; pregnancy; inability to use NRS; chronic opioid use \>60 mg oral morphine equivalents/day; contraindication to study analgesics.
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Menoufia University

OTHER

Sponsor Role lead

Responsible Party

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Amal Gouda Elsayed Safan

lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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AMAL G SAFAN, MD

Role: STUDY_DIRECTOR

Menoufia University

Locations

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Faculty of medicine,Menofia university hospitals

Cairo, Shibin El Kom, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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Menoufia University

Identifier Type: REGISTRY

Identifier Source: secondary_id

11/2025ANET2

Identifier Type: -

Identifier Source: org_study_id