Diagnostic Evaluation of Viral Persistence in Cervical Cancer

NCT ID: NCT07325682

Last Updated: 2026-01-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-04-30

Study Completion Date

2030-12-30

Brief Summary

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This study aims to evaluate the diagnostic value of an electroacupuncture-based method for detecting viral persistence (human papillomavirus and SARS-CoV-2) in patients with cervical cancer. The study investigates whether persistent viral signatures can be identified through measurable electrodiagnostic responses at acupuncture points associated with organ systems affected by chronic viral infection. The goal is to assess the feasibility, reproducibility, and potential clinical relevance of this diagnostic approach in oncology patients.

Detailed Description

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This study investigates the diagnostic potential of an electroacupuncture-based measurement method to detect viral persistence in patients with cervical cancer. Increasing evidence indicates that oncologic processes may be influenced by chronic viral activity, including persistent human papillomavirus (HPV) infection and, in some cases, secondary viral signatures such as SARS-CoV-2. Although HPV is the primary etiologic agent in cervical cancer, clinical observations suggest that long-term viral presence may contribute to variations in disease behavior, immune dysfunction, and treatment response.

The diagnostic method used in this study is based on measurement of electrical parameters at standardized acupuncture points. These points are functionally connected to organ systems involved in chronic viral disease. Changes in their electrical characteristics may reflect physiological responses associated with viral persistence. The technique has been previously developed and refined in clinical practice and has demonstrated reproducibility in identifying characteristic response patterns in patients with viral and post-viral conditions.

This study aims to evaluate whether measurable electrodiagnostic responses correlate with persistent viral signatures in cervical cancer patients. All participants undergo standardized diagnostic measurements performed under controlled conditions. The study does not involve therapeutic intervention, drug administration, or device implantation. Only diagnostic data are collected.

The primary objective is to assess whether this method can reliably identify patterns consistent with viral persistence. Secondary objectives include evaluating repeatability of measurements, describing characteristic profiles in this patient population, and assessing feasibility of integrating this diagnostic approach into clinical oncology settings.

This research is expected to contribute to a better understanding of viral involvement in cancer microenvironments and to support the development of non-invasive diagnostic tools for evaluating viral activity in oncologic patients.

Conditions

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Cervical Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Diagnostic evaluation of viral persistence using EAV-based measurement of viral activity in cervical cancer patients.

Study Groups

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Diagnostic Group

Non-invasive diagnostic method assessing bioelectrical response patterns associated with viral markers in patients with cervical cancer.

Group Type EXPERIMENTAL

Electroacupuncture

Intervention Type DIAGNOSTIC_TEST

Non-invasive electrodiagnostic assessment using electroacupuncture measurements to evaluate bioelectrical response patterns associated with viral markers in patients with cervical cancer.

Interventions

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Electroacupuncture

Non-invasive electrodiagnostic assessment using electroacupuncture measurements to evaluate bioelectrical response patterns associated with viral markers in patients with cervical cancer.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Histologically confirmed cervical cancer (FIGO stage IIIA-IVA)
* Age ≥21 years
* ECOG performance status adequate for diagnostic procedures
* Adequate organ function
* Ability to provide informed consent

Exclusion Criteria

* Poor renal function (elevated creatinine)
* Significant liver dysfunction (elevated bilirubin or liver enzymes)
* Severe cardiovascular or pulmonary disease
* Pregnancy or breastfeeding
* Severe mental illness or inability to provide informed consent
* Known non-compliance or substance abuse
Minimum Eligible Age

21 Years

Maximum Eligible Age

70 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Oncology Center,Ministry Of Heath,Uzbekistan

OTHER

Sponsor Role lead

Responsible Party

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Naylya Djumaeva

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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City Branch of the National Oncology and Radiology Center

Tashkent, , Uzbekistan

Site Status

Countries

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Uzbekistan

Other Identifiers

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CC-DIAG-001

Identifier Type: -

Identifier Source: org_study_id

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